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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:protoporphyrinogen
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Accession:CHEBI:15435 term browser browse the term
Definition:A porphyrinogen that has formula C34H40N4O4.
Synonyms:related_synonym: 7,12-diethenyl-3,8,13,17-tetramethyl-5,10,15,20,22,24-hexahydroporphyrin-2,18-dipropanoic acid;   Formula=C34H40N4O4;   InChI=1S/C34H40N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,35-38H,1-2,9-16H2,3-6H3,(H,39,40)(H,41,42);   InChIKey=UHSGPDMIQQYNAX-UHFFFAOYSA-N;   Protoporphyrinogen IX;   SMILES=Cc1c2Cc3[nH]c(Cc4[nH]c(Cc5[nH]c(Cc([nH]2)c1CCC(O)=O)c(CCC(O)=O)c5C)c(C=C)c4C)c(C=C)c3C
 alt_id: CHEBI:14962;   CHEBI:26359;   CHEBI:26360;   CHEBI:8593
 xref: Beilstein:1201533;   CAS:7412-77-3;   KEGG:C01079;   KNApSAcK:C00007371
 xref_mesh: MESH:C011539
 cyclic_relationship: is_conjugate_acid_of CHEBI:57307


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protoporphyrinogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpox coproporphyrinogen oxidase increases chemical synthesis
multiple interactions		 ISO CPOX protein results in increased chemical synthesis of protoporphyrinogen
Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]; TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]		 CTD PMID:11248690 PMID:19339664 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen] CTD PMID:11248690 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          cofactor 16167
            porphyrins 372
              porphyrinogens 2
                protoporphyrinogen 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  organonitrogen heterocyclic compound 18151
                                    polypyrrole 697
                                      tetrapyrrole 585
                                        cyclic tetrapyrrole 455
                                          porphyrins 372
                                            porphyrinogens 2
                                              protoporphyrinogen 2
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