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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:protoporphyrinogen
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Accession:CHEBI:15435 term browser browse the term
Definition:A porphyrinogen that has formula C34H40N4O4.
Synonyms:related_synonym: 7,12-diethenyl-3,8,13,17-tetramethyl-5,10,15,20,22,24-hexahydroporphyrin-2,18-dipropanoic acid;   Formula=C34H40N4O4;   InChI=1S/C34H40N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,35-38H,1-2,9-16H2,3-6H3,(H,39,40)(H,41,42);   InChIKey=UHSGPDMIQQYNAX-UHFFFAOYSA-N;   Protoporphyrinogen IX;   SMILES=Cc1c2Cc3[nH]c(Cc4[nH]c(Cc5[nH]c(Cc([nH]2)c1CCC(O)=O)c(CCC(O)=O)c5C)c(C=C)c4C)c(C=C)c3C
 alt_id: CHEBI:14962;   CHEBI:26359;   CHEBI:26360;   CHEBI:8593
 xref: Beilstein:1201533;   CAS:7412-77-3;   KEGG:C01079;   KNApSAcK:C00007371
 xref_mesh: MESH:C011539
 cyclic_relationship: is_conjugate_acid_of CHEBI:57307


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protoporphyrinogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpox coproporphyrinogen oxidase increases chemical synthesis
multiple interactions
ISO CPOX protein results in increased chemical synthesis of protoporphyrinogen
Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]; TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]
CTD PMID:11248690 PMID:19339664 NCBI chr11:44,039,665...44,049,648
Ensembl chr11:44,039,669...44,049,648
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen] CTD PMID:11248690 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        biochemical role 19360
          cofactor 15575
            porphyrins 343
              porphyrinogens 2
                protoporphyrinogen 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic molecule 19586
                              organic cyclic compound 19395
                                organic heterocyclic compound 18511
                                  organonitrogen heterocyclic compound 17579
                                    polypyrrole 612
                                      tetrapyrrole 499
                                        cyclic tetrapyrrole 370
                                          porphyrins 343
                                            porphyrinogens 2
                                              protoporphyrinogen 2
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