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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:BAY 41-2272
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Accession:CHEBI:142435 term browser browse the term
Definition:A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted by a 2-fluorobenzyl group at position 1 and by a 4-amino-5-cyclopropylpyrimidin-2-yl group at position 3. It is an activator of soluble guanylate cyclase.
Synonyms:exact_synonym: 5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
 related_synonym: 5-cyclopropyl-2-(1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-4-pyrimidinamine;   BAY-412272;   Formula=C20H17FN6;   InChI=1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25);   InChIKey=ATOAHNRJAXSBOR-UHFFFAOYSA-N;   SMILES=C(N1N=C(C2=C1N=CC=C2)C=3N=C(C(=CN3)C4CC4)N)C=5C=CC=CC5F
 xref: CAS:256376-24-6;   PMID:11242081;   PMID:19188837;   PMID:20828552;   PMID:20977455;   PMID:21825001;   PMID:22044316;   PMID:22575520;   PMID:22634166;   PMID:24231204;   PMID:25230878;   PMID:25740897;   PMID:25742266;   PMID:26760319;   PMID:26873974;   PMID:27131967;   PMID:27895434;   PMID:29461815;   Patent:US6833364;   Reaxys:8867995


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        activator 107
          enzyme activator 68
            soluble guanylate cyclase activator 11
              BAY 41-2272 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    main group molecular entity 19782
                      s-block molecular entity 19620
                        hydrogen molecular entity 19607
                          hydrides 19113
                            inorganic hydride 18117
                              pnictogen hydride 18106
                                nitrogen hydride 18013
                                  azane 17821
                                    ammonia 17820
                                      organic amino compound 17820
                                        aromatic amine 15425
                                          aminopyrimidine 1928
                                            BAY 41-2272 0
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