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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-fluoxetine(1+)
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Accession:CHEBI:86993 term browser browse the term
Definition:An organic cation resulting from the protonation of the amino group of (R)-fluoxetine.
Synonyms:exact_synonym: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium
 related_synonym: (+)-fluoxetine(1+);   Formula=C17H19F3NO;   InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m1/s1;   InChIKey=RTHCYVBBDHJXIQ-MRXNPFEDSA-O;   SMILES=C[NH2+]CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: Reaxys:25263171
 cyclic_relationship: is_conjugate_acid_of CHEBI:86991;   is_enantiomer_of CHEBI:86995


show annotations for term's descendants           Sort by:
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      molecular entity 19806
        ion 16690
          organic ion 9858
            organic cation 8908
              (R)-fluoxetine(1+) 1
                (R)-fluoxetine hydrochloride + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  ammonium 8298
                                    ammonium ion derivative 8293
                                      (R)-fluoxetine(1+) 1
                                        (R)-fluoxetine hydrochloride + 1
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