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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-fluoxetine hydrochloride
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Accession:CHEBI:86996 term browser browse the term
Definition:A hydrochloride obtained by reaction of (R)-fluoxetine with one equivalent of hydrochloric acid.
Synonyms:exact_synonym: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
 related_synonym: (-)-fluoxetine hydrochloride;   (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium chloride;   (R)-fluoxetine HCl;   Formula=C17H19ClF3NO;   InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1;   InChIKey=GIYXAJPCNFJEHY-PKLMIRHRSA-N;   SMILES=Cl.CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: CAS:114247-09-5
 cyclic_relationship: is_enantiomer_of CHEBI:86997



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fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        pharmacological role 18850
          neurotransmitter agent 16461
            serotonergic drug 4006
              serotonin uptake inhibitor 3379
                (R)-fluoxetine hydrochloride 1
                  fluoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      halogen 18186
                        chlorine atom 18027
                          chlorine molecular entity 18027
                            elemental chlorine 8461
                              monoatomic chlorine 8445
                                chloride 8445
                                  chloride salt 8445
                                    organic chloride salt 909
                                      hydrochloride 686
                                        (R)-fluoxetine hydrochloride 1
                                          fluoxetine hydrochloride 1
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