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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:aflatoxin Q1
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Accession:CHEBI:78582 term browser browse the term
Definition:A member of the class of aflatoxins that is aflatoxin B1 in which the hydrogen at the pro-3S position is replaced by a hydroxy group.
Synonyms:exact_synonym: (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
 related_synonym: AFQ1;   Formula=C17H12O7;   InChI=1S/C17H12O7/c1-21-9-5-10-11(6-2-3-22-17(6)23-10)15-14(9)12-7(18)4-8(19)13(12)16(20)24-15/h2-3,5-7,17-18H,4H2,1H3/t6-,7-,17+/m0/s1;   InChIKey=GYNOTJLCULOEIM-XKRJZGAWSA-N;   SMILES=COc1cc2O[C@H]3OC=C[C@H]3c2c2oc(=O)c3C(=O)C[C@H](O)c3c12
 xref: CAS:52819-96-2;   HMDB:HMDB0030753;   KEGG:C19585;   KNApSAcK:C00023624
 xref_mesh: MESH:C033759
 xref: PMID:1185319;   PMID:1643250;   PMID:3099349;   PMID:3116726;   PMID:3141079;   PMID:4081304;   PMID:6622820;   PMID:6712219;   PMID:6766512;   PMID:7987484;   PMID:9385444;   Reaxys:8866397


show annotations for term's descendants           Sort by:
aflatoxin Q1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin Q1 CTD PMID:20707407 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gnmt glycine N-methyltransferase decreases secretion ISO GNMT results in decreased secretion of aflatoxin Q1 CTD PMID:19146867 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        aetiopathogenetic role 19196
          carcinogenic agent 18519
            aflatoxin Q1 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteropolycyclic compound 18301
                                    organic heteropentacyclic compound 13513
                                      cyclopentafurofurochromene 11152
                                        aflatoxin 11152
                                          aflatoxin B1 11152
                                            aflatoxin Q1 2
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