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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4-diaminobutyric acid
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Accession:CHEBI:64307 term browser browse the term
Definition:A diamino acid that is butyric acid in which a hydrogen at position 2 and a hydrogen at position 4 are replaced by amino groups.
Synonyms:related_synonym: 2,4-diaminobutanoic acid;   Dbu;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8);   InChIKey=OGNSCSPNOLGXSM-UHFFFAOYSA-N;   SMILES=NCCC(N)C(O)=O;   alpha,gamma-diaminobutanoic acid;   alpha,gamma-diaminobutyric acid
 xref: CAS:305-62-4
 xref_mesh: MESH:C005959
 xref: Reaxys:1721676



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2,4-diaminobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions EXP [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CASP3 protein CTD PMID:28634653 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G COX6B1 cytochrome c oxidase subunit 6B1 multiple interactions EXP [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of COX6B1 mRNA CTD PMID:28634653 NCBI chr19:35,648,323...35,658,782
Ensembl chr19:35,648,323...35,658,782
JBrowse link
G CTSB cathepsin B multiple interactions EXP [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSB protein CTD PMID:28634653 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CTSL cathepsin L multiple interactions EXP [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSL protein CTD PMID:28634653 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 multiple interactions EXP [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of GPT2 mRNA CTD PMID:28634653 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      application 25177
        NMR chemical shift reference compound 20291
          ammonia 19945
            organic amino compound 19945
              amino acid 17161
                diamino acid 57
                  2,4-diaminobutyric acid 5
                    D-2,4-diaminobutyric acid 0
                    L-2,4-diaminobutyric acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            heteroorganic entity 24770
                              organochalcogen compound 24383
                                organooxygen compound 24060
                                  carbon oxoacid 22761
                                    carboxylic acid 22741
                                      monocarboxylic acid 21745
                                        fatty acid 19090
                                          short-chain fatty acid 17994
                                            fatty acid 4:0 8284
                                              butyric acid 6785
                                                2,4-diaminobutyric acid 5
                                                  D-2,4-diaminobutyric acid 0
                                                  L-2,4-diaminobutyric acid + 0
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