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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzoquinolizine
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Accession:CHEBI:64027 term browser browse the term
Definition:Any organic heterotricyclic compound with a skeleton consisting of a quinolizine fused to a benzene ring.
Synonyms:related_synonym: benzoquinolizines


show annotations for term's descendants           Sort by:
9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 multiple interactions ISO Tetrabenazine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin] CTD PMID:8245983 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases activity
multiple interactions
affects binding		 ISO
EXP		 Tetrabenazine results in decreased activity of SLC18A2 protein
Tetrabenazine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]
Tetrabenazine binds to SLC18A2 protein		 CTD PMID:1438304 PMID:7912402 PMID:15475732 PMID:19616025 PMID:33378168 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
tetrabenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 multiple interactions ISO Tetrabenazine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin] CTD PMID:8245983 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding
decreases activity
multiple interactions		 ISO
EXP		 Tetrabenazine binds to SLC18A2 protein
Tetrabenazine results in decreased activity of SLC18A2 protein
Tetrabenazine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]
Tetrabenazine binds to Slc8a2 protein		 CTD
RGD		 PMID:1438304 PMID:7912402 PMID:15475732 PMID:19616025 PMID:33378168 More... RGD:5130957 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          nitrogen atom 18933
            nitrogen molecular entity 18933
              organonitrogen compound 18783
                organonitrogen heterocyclic compound 18126
                  benzoquinolizine 2
                    9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic heterocyclic compound 18848
                                  organic heteropolycyclic compound 18278
                                    organic heterotricyclic compound 15623
                                      benzoquinolizine 2
                                        9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one + 2
paths to the root