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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(E)-4-hydroxynon-2-enal
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Accession:CHEBI:58968 term browser browse the term
Definition:The E (trans) stereoisomer of 4-hydroxynon-2-enal; it is the primary alpha,beta-unsaturated hydroxyalkenal produced by lipid peroxidation in cells.
Synonyms:exact_synonym: (2E)-4-hydroxynon-2-enal
 related_synonym: (E)-4-hydroxy-2-nonenal;   4-Hydroxy-2,3-trans-nonenal;   4-hydroxynonenal;   Formula=C9H16O2;   HNE;   InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+;   InChIKey=JVJFIQYAHPMBBX-FNORWQNLSA-N;   SMILES=[H]C(=O)\\C=C\\C(O)CCCCC;   trans-4-Hydroxy-2-nonenal
 xref: CAS:18286-49-2;   LIPID_MAPS_instance:LMFA06000051;   PMID:16603628;   PMID:17189262;   PMID:23543734;   PMID:26800898


show annotations for term's descendants           Sort by:
(E)-4-hydroxynon-2-enal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta4 glutathione S-transferase alpha 4 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gsta4 protein RGD PMID:11018474 RGD:1641942 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gstp1 protein RGD PMID:11018474 RGD:1641942 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    role 19850
      application 19693
        solvent 17256
          formic acid 9424
            formyl group 9385
              aldehyde 9385
                hydroxyaldehyde 808
                  4-hydroxynonenal 806
                    (E)-4-hydroxynon-2-enal 2
                      (2E,4R)-4-hydroxynon-2-enal 0
                      (2E,4S)-4-hydroxynon-2-enal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      carbon group element atom 19756
                        carbon atom 19753
                          organic molecular entity 19753
                            heteroorganic entity 19521
                              organochalcogen compound 19281
                                organooxygen compound 19199
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      carboacyl group 17706
                                        univalent carboacyl group 17706
                                          formyl group 9385
                                            aldehyde 9385
                                              aliphatic aldehyde 2424
                                                fatty aldehyde 2152
                                                  unsaturated fatty aldehyde 818
                                                    monounsaturated fatty aldehyde 813
                                                      4-hydroxynonenal 806
                                                        4-hydroxynon-2-enal 806
                                                          (E)-4-hydroxynon-2-enal 2
                                                            (2E,4R)-4-hydroxynon-2-enal 0
                                                            (2E,4S)-4-hydroxynon-2-enal 0
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