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(E)-4-hydroxynon-2-enal - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(E)-4-hydroxynon-2-enal
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Accession:CHEBI:58968 term browser browse the term
Definition:The E (trans) stereoisomer of 4-hydroxynon-2-enal; it is the primary alpha,beta-unsaturated hydroxyalkenal produced by lipid peroxidation in cells.
Synonyms:exact_synonym: (2E)-4-hydroxynon-2-enal
 related_synonym: (E)-4-hydroxy-2-nonenal;   4-Hydroxy-2,3-trans-nonenal;   4-hydroxynonenal;   Formula=C9H16O2;   HNE;   InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+;   InChIKey=JVJFIQYAHPMBBX-FNORWQNLSA-N;   SMILES=[H]C(=O)\\C=C\\C(O)CCCCC;   trans-4-Hydroxy-2-nonenal
 xref: CAS:18286-49-2;   LIPID_MAPS_instance:LMFA06000051;   PMID:16603628;   PMID:17189262;   PMID:23543734;   PMID:26800898

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(E)-4-hydroxynon-2-enal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta4 glutathione S-transferase alpha 4 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gsta4 protein RGD PMID:11018474 RGD:1641942 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gstp1 protein RGD PMID:11018474 RGD:1641942 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        solvent 17470
          formic acid 9446
            formyl group 9407
              aldehyde 9407
                hydroxyaldehyde 811
                  4-hydroxynonenal 809
                    (E)-4-hydroxynon-2-enal 2
                      (2E,4R)-4-hydroxynon-2-enal 0
                      (2E,4S)-4-hydroxynon-2-enal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            heteroorganic entity 20215
                              organochalcogen compound 19902
                                organooxygen compound 19804
                                  carbon oxoacid 19150
                                    carboxylic acid 19147
                                      carboacyl group 18082
                                        univalent carboacyl group 18082
                                          formyl group 9407
                                            aldehyde 9407
                                              aliphatic aldehyde 2441
                                                fatty aldehyde 2168
                                                  unsaturated fatty aldehyde 821
                                                    monounsaturated fatty aldehyde 816
                                                      4-hydroxynonenal 809
                                                        4-hydroxynon-2-enal 809
                                                          (E)-4-hydroxynon-2-enal 2
                                                            (2E,4R)-4-hydroxynon-2-enal 0
                                                            (2E,4S)-4-hydroxynon-2-enal 0
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