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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-hydroxynon-2-enal
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Accession:CHEBI:32585 term browser browse the term
Definition:An enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position.
Synonyms:related_synonym: 4-HNE;   4-Hydroxy-2,3-nonenal;   4-Hydroxy-2-nonenal;   4-Hydroxynonenal;   Formula=C9H16O2;   HNE;   InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3;   InChIKey=JVJFIQYAHPMBBX-UHFFFAOYSA-N;   SMILES=[H]C(=CC=O)C(O)CCCCC
 xref: CAS:29343-52-0;   LINCS:LSM-4344
 xref_mesh: MESH:C027576
 xref: Wikipedia:4-Hydroxynonenal


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4-hydroxynon-2-enal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ABCA1 mRNA CTD PMID:19191707 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects binding
increases expression
multiple interactions
ISO 4-hydroxy-2-nonenal binds to ABCC1 protein
4-hydroxy-2-nonenal results in increased expression of ABCC1 mRNA
[GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:15672542 PMID:19191707 PMID:21925487 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
EXP
ISO
ABCC2 protein affects the export of 4-hydroxy-2-nonenal metabolite
4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]
CTD PMID:12623073 PMID:19326901 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle affects binding EXP 4-hydroxy-2-nonenal binds to ACTA1 protein CTD PMID:15886073 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Actb actin, beta affects binding ISO ACTB protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actn1 actinin, alpha 1 affects binding ISO ACTN1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Actn4 actinin alpha 4 affects binding ISO ACTN4 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADH7 mRNA CTD PMID:19191707 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Adi1 acireductone dioxygenase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADI1 mRNA CTD PMID:19191707 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ADORA1 mRNA CTD PMID:12419474 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2b adenosine A2B receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ADORA2B mRNA CTD PMID:19191707 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADRB2 mRNA CTD PMID:19191707 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ago2 argonaute RISC catalytic component 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AGO2 mRNA CTD PMID:19191707 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Ago3 argonaute RISC catalytic component 3 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of AGO3 mRNA
4-hydroxy-2-nonenal results in increased expression of AGO3 mRNA
CTD PMID:19191707 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Agrn agrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AGRN mRNA CTD PMID:19191707 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Agt angiotensinogen affects binding
multiple interactions
ISO 4-hydroxy-2-nonenal binds to AGT protein modified form; AGT protein modified form binds to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal binds to and results in increased lipidation of AGT protein modified form; [AGT protein modified form results in increased chemical synthesis of Lipid Peroxides] which results in increased abundance of 4-hydroxy-2-nonenal; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]
CTD PMID:20977208 PMID:26111765 PMID:31144504 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AHSA2 mRNA CTD PMID:19191707 NCBI chr14:97,474,465...97,485,725
Ensembl chr14:97,476,817...97,485,657
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AIFM1 mRNA CTD PMID:19191707 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akna AT-hook transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AKNA mRNA CTD PMID:19191707 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction
increases expression
ISO AKR1A1 protein results in increased reduction of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased expression of AKR1A1 mRNA
CTD PMID:10510318 PMID:19191707 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B affects reduction
increases reduction
ISO AKR1B1 protein affects the reduction of 4-hydroxy-2-nonenal
AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal; AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal metabolite
CTD PMID:9890881 PMID:10510318 PMID:11306073 PMID:21329684 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
increases metabolic processing
ISO AKR1B10 protein results in increased reduction of 4-hydroxy-2-nonenal
Oleanolic Acid inhibits the reaction [AKR1B10 protein results in increased metabolism of 4-hydroxy-2-nonenal]
CTD PMID:19013440 PMID:21329684 PMID:27417252 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 4-hydroxy-2-nonenal CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
increases response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in increased expression of AKR1C3 mRNA; 4-hydroxy-2-nonenal results in increased expression of AKR1C3 protein
AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal
7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal]
CTD PMID:22964423 PMID:30849339 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases response to substance
affects response to substance
increases response to substance
multiple interactions
increases expression
ISO AKR7A2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
AKR7A2 protein affects the susceptibility to 4-hydroxy-2-nonenal
AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal
7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal]; AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal]
4-hydroxy-2-nonenal results in increased expression of AKR7A2 mRNA; 4-hydroxy-2-nonenal results in increased expression of AKR7A2 protein
CTD PMID:22001351 PMID:22964423 PMID:30849339 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects response to substance
decreases phosphorylation
increases activity
multiple interactions
EXP
ISO
AKT1 protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in decreased phosphorylation of AKT1 protein
4-hydroxy-2-nonenal results in increased activity of AKT1 protein
AKT1 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2 protein]
CTD PMID:18805481 PMID:23845594 PMID:24825450 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases metabolic processing
increases oxidation
multiple interactions
ISO ALDH1A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH1A1 protein results in increased oxidation of 4-hydroxy-2-nonenal
[APC protein mutant form results in increased expression of ALDH1A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:21256123 PMID:21967605 PMID:22339434 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions
increases oxidation
ISO [APC protein mutant form results in increased expression of ALDH2 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
ALDH2 protein results in increased oxidation of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal binds to and results in decreased activity of ALDH2 protein; ALDH2 protein inhibits the reaction [Rotenone results in increased abundance of 4-hydroxy-2-nonenal]
CTD PMID:21967605 PMID:22339434 PMID:25263579 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases response to substance
increases oxidation
multiple interactions
increases metabolic processing
affects response to substance
affects metabolic processing
ISO
EXP
ALDH3A1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
ALDH3A1 protein results in increased oxidation of 4-hydroxy-2-nonenal
[APC protein mutant form results in increased expression of ALDH3A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
ALDH3A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH3A1 protein affects the susceptibility to 4-hydroxy-2-nonenal
ALDH3A1 protein affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:11018474 PMID:11306050 PMID:15905174 PMID:21256123 PMID:21967605 More... NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding
decreases response to substance
ISO 4-hydroxy-2-nonenal binds to ALDH3B1 protein
ALDH3B1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:20699116 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALDH6A1 mRNA CTD PMID:19191707 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 increases metabolic processing
decreases response to substance
ISO ALDH7A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH7A1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:21338592 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A affects binding ISO ALDOA protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to ALDOA protein] CTD PMID:20889679 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein] CTD PMID:19837106 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALOX5AP mRNA CTD PMID:19191707 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Alpk1 alpha-kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ALPK1 mRNA CTD PMID:19191707 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALS2 mRNA CTD PMID:19191707 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
JBrowse link
G Amph amphiphysin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AMPH mRNA CTD PMID:12419474 NCBI chr17:45,739,385...45,982,905 JBrowse link
G Anln anillin, actin binding protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ANLN mRNA CTD PMID:19191707 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ANP32A mRNA CTD PMID:19191707
G Aoah acyloxyacyl hydrolase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AOAH mRNA CTD PMID:19191707 NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AOX1 mRNA CTD PMID:19191707 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AP1S3 mRNA CTD PMID:19191707 NCBI chr 9:80,950,402...81,039,685
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
affects oxidation
affects response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of APC mRNA
APC protein affects the oxidation of 4-hydroxy-2-nonenal
APC protein affects the susceptibility to 4-hydroxy-2-nonenal
[APC protein affects the oxidation of 4-hydroxy-2-nonenal] which affects the abundance of 4-hydroxynonenoic acid; [APC protein mutant form results in increased expression of ALDH1A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of ALDH2 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of ALDH3A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of GSTA4 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of SLC7A11 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:12419474 PMID:21967605 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of APEX1 mRNA CTD PMID:19191707 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa1 apolipoprotein A1 affects binding ISO 4-hydroxy-2-nonenal binds to APOA1 protein CTD PMID:18778096 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apod apolipoprotein D decreases abundance ISO APOD protein results in decreased abundance of 4-hydroxy-2-nonenal CTD PMID:28182653 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of APP mRNA
[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]
CTD PMID:12419474 PMID:17964426 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGAP11A mRNA CTD PMID:19191707 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARHGAP22 mRNA CTD PMID:19191707 NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548
JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARHGAP27 mRNA CTD PMID:19191707 NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGAP5 mRNA CTD PMID:12419474 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGDIA mRNA CTD PMID:12419474 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGEF3 mRNA CTD PMID:19191707 NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
JBrowse link
G Arid5a AT-rich interaction domain 5A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARID5A mRNA CTD PMID:19191707 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARRDC3 mRNA CTD PMID:19191707 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of ASF1B mRNA
4-hydroxy-2-nonenal results in increased expression of ASF1B mRNA
CTD PMID:19191707 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ASPM mRNA CTD PMID:19191707 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ATAD5 mRNA CTD PMID:19191707 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATF3 protein CTD PMID:19041636 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of ATF4 mRNA; 4-hydroxy-2-nonenal results in increased expression of ATF4 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein]
CTD PMID:24291486 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form]
CTD PMID:24291486 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATM mRNA CTD PMID:19191707 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ATP1B3 mRNA CTD PMID:12419474 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects binding ISO 4-hydroxy-2-nonenal binds to ATP5F1A protein CTD PMID:19374891 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATP6V1A mRNA CTD PMID:19191707 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atr ATR serine/threonine kinase decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of ATR mRNA
4-hydroxy-2-nonenal results in increased expression of ATR mRNA
CTD PMID:12419474 PMID:19191707 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Avil advillin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AVIL mRNA CTD PMID:19191707 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of B2M mRNA CTD PMID:19191707 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BABAM2 mRNA CTD PMID:19191707 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of BAD mRNA
4-hydroxy-2-nonenal results in increased expression of BAD protein
CTD PMID:12419474 PMID:24825450 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Batf2 basic leucine zipper ATF-like transcription factor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BATF2 mRNA CTD PMID:19191707 NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of BAX mRNA
4-hydroxy-2-nonenal results in increased expression of BAX protein
CTD PMID:12419474 PMID:15607904 PMID:21187080 PMID:24825450 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
EXP 4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA] CTD PMID:24291486 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bbx BBX high mobility group box domain containing increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BBX mRNA CTD PMID:19191707 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCAR3 mRNA CTD PMID:19191707 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL2A1B mRNA CTD PMID:19191707 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL2L1 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BCL2L11 mRNA CTD PMID:19191707 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL3 mRNA CTD PMID:19191707 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BCL6 mRNA CTD PMID:19191707 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA
CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA]
CTD PMID:16337876 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BHLHE40 mRNA CTD PMID:19191707 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BHLHE41 mRNA CTD PMID:19191707 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BID mRNA CTD PMID:19191707 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of BIRC5 mRNA
4-hydroxy-2-nonenal results in decreased expression of BIRC5 mRNA
CTD PMID:19191707 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BLM mRNA CTD PMID:19191707 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BLVRB mRNA CTD PMID:19191707 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BMP1 mRNA CTD PMID:12419474 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BNIP3 mRNA CTD PMID:12419474 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BRAF mRNA CTD PMID:12419474 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BUB1 mRNA CTD PMID:19191707 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BUB1B mRNA CTD PMID:19191707 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BZW1 mRNA CTD PMID:19191707 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C5ar1 complement C5a receptor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of C5AR1 mRNA CTD PMID:19191707 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAR12 mRNA CTD PMID:19191707 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CACNA1A mRNA CTD PMID:19191707 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cadps calcium dependent secretion activator increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CADPS mRNA CTD PMID:19191707 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779
JBrowse link
G Calca calcitonin-related polypeptide alpha increases secretion EXP 4-hydroxy-2-nonenal results in increased secretion of CALCA protein CTD PMID:17684094 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CALCOCO1 mRNA CTD PMID:19191707 NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422
JBrowse link
G Calr3 calreticulin 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CALR3 mRNA CTD PMID:19191707 NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAMK1D mRNA CTD PMID:19191707 NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 affects binding ISO CAP1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Capn2 calpain 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CAPN2 mRNA CTD PMID:12419474 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CAPNS1 mRNA CTD PMID:12419474 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta affects binding ISO CAPZB protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Car2 carbonic anhydrase 2 affects binding ISO CA2 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CARHSP1 mRNA CTD PMID:19191707 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASK mRNA CTD PMID:12419474 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Casp1 caspase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP1 mRNA CTD PMID:19191707 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
ISO
EXP
4-hydroxy-2-nonenal results in increased cleavage of and results in increased activity of CASP3 protein; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]
4-hydroxy-2-nonenal results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]
CTD PMID:11488593 PMID:16322078 PMID:16337876 PMID:17263905 PMID:19326901 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP4 mRNA CTD PMID:19191707 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP7 mRNA CTD PMID:19191707 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP8 mRNA CTD PMID:12419474 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased activity of CASP9 protein
pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP9 protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP9 protein]
CTD PMID:16322078 PMID:17263905 PMID:21187080 PMID:24825450 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAT mRNA CTD PMID:19191707 PMID:24423726 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CBLB mRNA CTD PMID:12419474 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CCL17 mRNA
4-hydroxy-2-nonenal results in increased expression of CCL17 mRNA
CTD PMID:19191707 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL2 mRNA CTD PMID:19191707 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL22 mRNA CTD PMID:19191707 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL3 mRNA CTD PMID:12419474 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL4 mRNA CTD PMID:19191707 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression
ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein]
4-hydroxy-2-nonenal results in decreased expression of CCL5 mRNA
CTD PMID:19191707 PMID:19627980 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL6 mRNA CTD PMID:19191707 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL7 mRNA CTD PMID:19191707 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNA2 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNB1 mRNA CTD PMID:19191707 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of CCND1]
4-hydroxy-2-nonenal results in increased expression of CCND1; 4-hydroxy-2-nonenal results in increased expression of CCND1 mRNA
CTD PMID:16328008 PMID:19191707 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCND2 protein CTD PMID:15607904 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnf cyclin F decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNF mRNA CTD PMID:19191707 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Ccng1 cyclin G1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CCNG1 mRNA CTD PMID:19191707 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNG2 mRNA CTD PMID:19191707 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccnk cyclin K decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNK mRNA CTD PMID:12419474 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
JBrowse link
G Ccnt1 cyclin T1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNT1 mRNA CTD PMID:12419474 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCR1 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd14 CD14 molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD14 mRNA CTD PMID:19191707 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd300a Cd300a molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD300A mRNA CTD PMID:19191707 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd300lb CD300 molecule-like family member b increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD300LB mRNA CTD PMID:19191707 NCBI chr10:99,964,801...99,974,790
Ensembl chr10:99,964,801...99,974,790
JBrowse link
G Cd300lf Cd300 molecule-like family member F decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD300LF mRNA CTD PMID:19191707 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041
JBrowse link
G Cd36 CD36 molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD36 mRNA CTD PMID:19191707 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd40 CD40 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD40 mRNA CTD PMID:19191707 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD44 mRNA CTD PMID:19191707 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd47 Cd47 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD47 mRNA CTD PMID:12419474 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd83 CD83 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD83 mRNA CTD PMID:19191707 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD86 mRNA CTD PMID:19191707 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC20 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC25A mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC25C mRNA CTD PMID:19191707 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDCA2 mRNA CTD PMID:19191707 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDH2 mRNA CTD PMID:12419474 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh3 cadherin 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDH3 mRNA CTD PMID:12419474 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO 4-hydroxy-2-nonenal binds to and results in increased alkylation of and results in decreased activity of CDK2 protein CTD PMID:26910110 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CDK6 mRNA CTD PMID:19191707 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDK9 mRNA CTD PMID:12419474 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CDKN1A protein CTD PMID:15607904 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDKN1C mRNA CTD PMID:12419474 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDKN2D mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CEBPA mRNA CTD PMID:19191707 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cenpa centromere protein A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CENPA mRNA CTD PMID:19191707 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CEP290 mRNA CTD PMID:19191707 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Ces1d carboxylesterase 1D decreases activity ISO 4-hydroxy-2-nonenal results in decreased activity of CES1 protein CTD PMID:21878322 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2h carboxylesterase 2H increases activity ISO 4-hydroxy-2-nonenal results in increased activity of CES2 protein CTD PMID:21878322 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfb complement factor B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CFB mRNA CTD PMID:19191707 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Cfl1 cofilin 1 affects binding ISO CFL1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CHEK1 mRNA CTD PMID:19191707 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chml CHM like Rab escort protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CHML mRNA CTD PMID:19191707 NCBI chr13:87,613,610...87,615,475
Ensembl chr13:87,589,298...87,619,862
JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CILK1 mRNA CTD PMID:19191707 NCBI chr 8:78,984,075...79,042,695
Ensembl chr 8:78,984,258...79,042,691
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CISH mRNA CTD PMID:19191707 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CKS1B mRNA CTD PMID:19191707 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CKS2 mRNA CTD PMID:19191707 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn11 claudin 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CLDN11 mRNA CTD PMID:19191707 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clec12a C-type lectin domain family 12, member A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC12A mRNA CTD PMID:19191707 NCBI chr 4:162,798,125...162,816,757
Ensembl chr 4:162,798,125...162,816,753
JBrowse link
G Clec4a C-type lectin domain family 4, member A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC4N mRNA CTD PMID:19191707 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CLEC4D mRNA CTD PMID:19191707 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clec5a C-type lectin domain containing 5A decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC5A mRNA
4-hydroxy-2-nonenal results in increased expression of CLEC5A mRNA
CTD PMID:19191707 NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859
JBrowse link
G Clk3 CDC-like kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLK3 mRNA CTD PMID:12419474 NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO 4-hydroxy-2-nonenal results in increased expression of COL1A1 mRNA; 4-hydroxy-2-nonenal results in increased expression of COL1A1 protein CTD PMID:14672615 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Comt catechol-O-methyltransferase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of COMT mRNA CTD PMID:12419474 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cp ceruloplasmin decreases expression
affects abundance
ISO 4-hydroxy-2-nonenal results in decreased expression of CP mRNA
CP protein affects the abundance of 4-hydroxy-2-nonenal
CTD PMID:12572680 PMID:19191707 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpe carboxypeptidase E decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CPE mRNA CTD PMID:12419474 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression
increases phosphorylation
ISO 4-hydroxy-2-nonenal results in decreased expression of CREB1 mRNA
4-hydroxy-2-nonenal results in increased phosphorylation of CREB1 protein
CTD PMID:12419474 PMID:16337876 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein multiple interactions EXP CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA] CTD PMID:16337876 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CREG1 mRNA CTD PMID:19191707 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CROT mRNA CTD PMID:19191707 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRY1 mRNA CTD PMID:19191707 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRY2 mRNA CTD PMID:19191707 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Cryz crystallin zeta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRYZ mRNA CTD PMID:12419474 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CSF1R mRNA CTD PMID:19191707 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CSF2 mRNA CTD PMID:19191707 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CSF3 mRNA
4-hydroxy-2-nonenal results in increased expression of CSF3 mRNA; 4-hydroxy-2-nonenal results in increased expression of CSF3 protein
CTD PMID:19191707 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CSNK1G2 mRNA CTD PMID:12419474 NCBI chr 7:9,076,739...9,095,082
Ensembl chr 7:9,076,740...9,095,052
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AXUD1 mRNA CTD PMID:19191707 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTNNB1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of CTNNB1 protein CTD PMID:12419474 PMID:24825450 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsl cathepsin L decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTSL mRNA CTD PMID:12419474 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cttn cortactin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTTN mRNA CTD PMID:12419474 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cux1 cut-like homeobox 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CUX1 mRNA CTD PMID:12419474 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein] CTD PMID:19627980 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CXCL14 mRNA CTD PMID:19191707 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CXCL1 mRNA CTD PMID:19191707 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CXCR4 mRNA CTD PMID:19191707 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cybb cytochrome b-245 beta chain increases abundance ISO CYBB protein results in increased abundance of 4-hydroxy-2-nonenal CTD PMID:19417757 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal affects the localization of CYCS protein
pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal affects the localization of CYCS protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal affects the localization of CYCS protein]
CTD PMID:16322078 PMID:17263905 PMID:21187080 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP1A2 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYP1B1 mRNA CTD PMID:12419474 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [CYP2B6 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2B6 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2B6 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO [CYP2C29 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2C29 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2C29 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 multiple interactions ISO [CYP2J2 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2J2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2J2 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [[CYP3A4 protein co-treated with Oxygen co-treated with NADP] results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; [CYP3A4 protein co-treated with Oxygen co-treated with NADP] results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal; [CYP3A4 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid CTD PMID:21766881 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYSLTR1 mRNA CTD PMID:19191707 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Cyth4 cytohesin 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYTH4 mRNA CTD PMID:19191707 NCBI chr 7:110,152,232...110,176,741
Ensembl chr 7:110,152,272...110,176,741
JBrowse link
G Dap death-associated protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of DAP mRNA CTD PMID:19191707 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DAPK1 mRNA CTD PMID:12419474 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DBF4 mRNA CTD PMID:19191707 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Dcn decorin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DCN mRNA CTD PMID:19191707 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA; 4-hydroxy-2-nonenal results in increased expression of DDIT3 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA]
CTD PMID:24291486 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDIT4 mRNA CTD PMID:19191707 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDR2 mRNA CTD PMID:12419474 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Ddx58 DEXD/H-box helicase 58 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDX58 mRNA CTD PMID:19191707 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Denr density regulated reinitiation and release factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DENR mRNA CTD PMID:19191707 NCBI chr12:32,662,512...32,685,283
Ensembl chr12:32,662,516...32,683,843
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DFFA mRNA CTD PMID:12419474 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DFFB mRNA CTD PMID:12419474 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dgkh diacylglycerol kinase, eta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DGKH mRNA CTD PMID:19191707 NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706
JBrowse link
G Dhx58 DEXH-box helicase 58 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DHX58 mRNA CTD PMID:19191707 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DIO2 mRNA CTD PMID:19191707 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of DLGAP5 mRNA
4-hydroxy-2-nonenal results in increased expression of DLGAP5 mRNA
CTD PMID:19191707 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of DNAJB4 mRNA CTD PMID:19191707 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DNAJC3 mRNA CTD PMID:12419474 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DNPH1 mRNA CTD PMID:12419474 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 affects binding ISO 4-hydroxy-2-nonenal binds to DPYSL2 protein CTD PMID:19374891 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP 4-hydroxy-2-nonenal results in decreased expression of DRD2 protein CTD PMID:20570720 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dst dystonin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DST mRNA CTD PMID:12419474 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 affects binding ISO DYNLT3 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr  X:13,327,933...13,337,139
Ensembl chr  X:13,327,892...13,337,139
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of E2F1 mRNA CTD PMID:12419474 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of E2F2 mRNA CTD PMID:19191707 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of E2F8 mRNA CTD PMID:19191707 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ECHDC3 mRNA CTD PMID:19191707 NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
JBrowse link
G Edn1 endothelin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EDN1 mRNA CTD PMID:19191707 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression EXP 4-hydroxy-2-nonenal results in decreased expression of EEF2 protein CTD PMID:16469450 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Efna4 ephrin A4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EFNA4 mRNA CTD PMID:12419474 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EID3 mRNA CTD PMID:19191707 NCBI chr 7:20,860,073...20,861,395 JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2A protein CTD PMID:19041636 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EIF2AK2 mRNA CTD PMID:19191707 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2AK3 protein CTD PMID:19041636 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
EXP Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein] CTD PMID:24291486 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF4E mRNA CTD PMID:19191707 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF4E2 mRNA CTD PMID:19191707 NCBI chr 9:87,886,078...87,901,058
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation EXP 4-hydroxy-2-nonenal results in increased phosphorylation of EIF4EBP1 protein CTD PMID:9890986 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF5A mRNA CTD PMID:19191707 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Elk1 ETS transcription factor ELK1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELK1 mRNA CTD PMID:12419474 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Eloc elongin C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELOC mRNA CTD PMID:12419474 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELP1 mRNA CTD PMID:12419474 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EME1 mRNA CTD PMID:19191707 NCBI chr10:79,586,736...79,595,515
Ensembl chr10:79,586,729...79,595,435
JBrowse link
G Eno1 enolase 1 affects binding ISO 4-hydroxy-2-nonenal binds to ENO1 protein CTD PMID:19374891 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EPHX1 mRNA CTD PMID:19191707 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPS15 mRNA CTD PMID:12419474 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPS8 mRNA CTD PMID:12419474 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Epsti1 epithelial stromal interaction 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPSTI1 mRNA CTD PMID:19191707 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERBB2 mRNA CTD PMID:12419474 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERBB4 mRNA CTD PMID:12419474 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC1 mRNA CTD PMID:19191707 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC2 mRNA CTD PMID:12419474 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC5 mRNA CTD PMID:12419474 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC6L mRNA CTD PMID:19191707 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERN1 mRNA CTD PMID:19191707 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ESPL1 mRNA CTD PMID:19191707 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETS1 mRNA CTD PMID:12419474 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETS2 mRNA CTD PMID:12419474 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Etv3 ETS variant transcription factor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETV3 mRNA CTD PMID:12419474 NCBI chr 2:172,965,461...172,980,320
Ensembl chr 2:172,965,588...172,980,314
JBrowse link
G Etv6 ETS variant transcription factor 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETV6 mRNA CTD PMID:12419474 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Ezr ezrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EZR mRNA CTD PMID:12419474 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F10 coagulation factor X increases expression ISO 4-hydroxy-2-nonenal results in increased expression of F10 mRNA CTD PMID:19191707 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of F2R mRNA CTD PMID:12419474 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of F3 mRNA CTD PMID:19191707 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fancd2 FA complementation group D2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FANCD2 mRNA CTD PMID:19191707 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FASTK mRNA CTD PMID:12419474 NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430
JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXL17 mRNA CTD PMID:19191707 NCBI chr 9:102,780,573...103,206,755
Ensembl chr 9:102,782,440...103,208,950
JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of FBXL20 mRNA
4-hydroxy-2-nonenal results in increased expression of FBXL20 mRNA
CTD PMID:19191707 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162
JBrowse link
G Fbxo15 F-box protein 15 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO15 mRNA CTD PMID:19191707 NCBI chr18:78,296,999...78,634,695
Ensembl chr18:78,319,534...78,390,765
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO22 mRNA CTD PMID:19191707 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
JBrowse link
G Fbxo30 F-box protein 30 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO30 mRNA CTD PMID:19191707 NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO31 mRNA CTD PMID:19191707 NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010
JBrowse link
G Fbxo39 F-box protein 39 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO39 mRNA CTD PMID:19191707 NCBI chr10:56,929,699...56,934,911
Ensembl chr10:56,932,297...56,934,906
JBrowse link
G Fbxo5 F-box protein 5 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO5 mRNA
4-hydroxy-2-nonenal results in increased expression of FBXO5 mRNA
CTD PMID:19191707 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FCGR1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of FCGR1A mRNA CTD PMID:19191707 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FCGR2B mRNA CTD PMID:19191707 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcrl1 Fc receptor-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FCRL1 mRNA CTD PMID:19191707 NCBI chr 2:172,809,451...172,829,780
Ensembl chr 2:172,790,934...172,829,753
JBrowse link
G Fech ferrochelatase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FECH mRNA CTD PMID:12419474 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fem1c fem-1 homolog C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FEM1C mRNA CTD PMID:19191707 NCBI chr18:39,232,900...39,258,692
Ensembl chr18:39,232,900...39,258,692
JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of FEN1 mRNA
4-hydroxy-2-nonenal results in decreased expression of FEN1 mRNA
CTD PMID:19191707 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FGFR1 mRNA CTD PMID:12419474 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of FGR mRNA
4-hydroxy-2-nonenal results in decreased expression of FGR mRNA
CTD PMID:19191707 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FKBP14 mRNA CTD PMID:19191707 NCBI chr 4:83,705,531...83,721,515
Ensembl chr 4:83,705,652...83,721,528
JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FKBPL mRNA CTD PMID:19191707 NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of FOS mRNA
resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of FOS protein]
CTD PMID:12419474 PMID:16322078 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]] CTD PMID:9890986 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FOXM1 mRNA CTD PMID:19191707 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO FOXO3 protein inhibits the reaction [SRT1720 inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal]] CTD PMID:24633890 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp1 forkhead box P1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FOXP1 mRNA CTD PMID:19191707 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Fpr3 formyl peptide receptor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FPR3 mRNA CTD PMID:19191707 NCBI chr 1:58,884,400...58,893,475
Ensembl chr 1:58,845,118...58,893,467
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FUBP1 mRNA CTD PMID:12419474 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fxn frataxin multiple interactions ISO 4-hydroxy-2-nonenal affects the reaction [Ethanol affects the expression of FXN protein] CTD PMID:33017621 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of G6PDX mRNA CTD PMID:19191707 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GABARAPL1 mRNA CTD PMID:19191707 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA]
CTD PMID:19191707 PMID:24291486 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gak cyclin G associated kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GAK mRNA CTD PMID:12419474 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO [Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]] which results in decreased activity of GAPDH protein; [Hydroxyurea results in increased abundance of Free Radicals] promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]; Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein] CTD PMID:20889679 PMID:23696560 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gata3 GATA binding protein 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GATA3 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GATAD2B mRNA CTD PMID:19191707 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GATB mRNA CTD PMID:19191707 NCBI chr 2:170,930,536...171,017,062
Ensembl chr 2:170,930,542...171,016,695
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP1 mRNA CTD PMID:19191707 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gbp4 guanylate binding protein 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP3 mRNA CTD PMID:19191707 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
JBrowse link
G Gbp5 guanylate binding protein 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP5 mRNA CTD PMID:19191707 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GCLC mRNA
4-hydroxy-2-nonenal results in increased expression of GCLC protein
NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GCLC mRNA]
CTD PMID:19191707 PMID:24291486 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GCLM mRNA CTD PMID:19191707 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GEN1 mRNA CTD PMID:19191707 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
JBrowse link
G Ggnbp1 gametogenetin binding protein 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GGNBP1 mRNA CTD PMID:19191707 NCBI chr20:5,109,849...5,116,185
Ensembl chr20:5,099,311...5,116,183
JBrowse link
G Gna13 G protein subunit alpha 13 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNA13 mRNA CTD PMID:19191707 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Gnaq G protein subunit alpha q increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GNAQ mRNA CTD PMID:19191707 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gnas GNAS complex locus decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNAS mRNA CTD PMID:12419474 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnat3 G protein subunit alpha transducin 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GNAT3 mRNA CTD PMID:19191707 NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283
JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNB1 mRNA CTD PMID:12419474 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNB2 mRNA CTD PMID:12419474 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GOT2 protein] CTD PMID:20889679 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpr183 G protein-coupled receptor 183 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GPR183 mRNA CTD PMID:19191707 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Gpx1 glutathione peroxidase 1 increases abundance ISO GPX1 gene mutant form results in increased abundance of 4-hydroxy-2-nonenal CTD PMID:24296279 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GPX2 mRNA CTD PMID:12419474 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
decreases phosphorylation
ISO 4-hydroxy-2-nonenal results in decreased expression of GSK3B mRNA
4-hydroxy-2-nonenal results in decreased phosphorylation of GSK3B protein
CTD PMID:12419474 PMID:24825450 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSN mRNA CTD PMID:19191707 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSR mRNA CTD PMID:19191707 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSS mRNA CTD PMID:19191707 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases response to substance
multiple interactions
affects metabolic processing
increases expression
ISO
EXP
GSTA1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
[GSTA1 protein binds to GSTA3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
GSTA1 protein affects the metabolism of 4-hydroxy-2-nonenal analog
4-hydroxy-2-nonenal results in increased expression of GSTA1 mRNA
CTD PMID:9799558 PMID:11256969 PMID:15829614 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GSTA3 mRNA
[GSTA1 protein binds to GSTA3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969 PMID:24423726 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
affects metabolic processing
increases expression
ISO
EXP
GSTA4 protein binds to and affects the metabolism of 4-hydroxy-2-nonenal
GSTA4 protein affects the metabolism of 4-hydroxy-2-nonenal; GSTA4 protein affects the metabolism of 4-hydroxy-2-nonenal analog
4-hydroxy-2-nonenal results in increased expression of GSTA4 mRNA; 4-hydroxy-2-nonenal results in increased expression of GSTA4 protein
CTD PMID:2619714 PMID:7878679 PMID:8142470 PMID:8203886 PMID:9461507 More... NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSTA1 mRNA CTD PMID:19191707 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
affects metabolic processing
ISO
EXP
[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione; [GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal
[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
GSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969 PMID:21925487 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases response to substance
affects metabolic processing
multiple interactions
ISO
EXP
GSTM2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
GSTM2 protein affects the metabolism of 4-hydroxy-2-nonenal analog
[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969 PMID:15829614 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression
affects binding
decreases response to substance
ISO
EXP
4-hydroxy-2-nonenal binds to and results in decreased activity of GSTP1 protein
4-hydroxy-2-nonenal results in increased expression of GSTP1 mRNA
Glutathione inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of GSTP1 protein]
4-hydroxy-2-nonenal analog binds to GSTP1
4-hydroxy-2-nonenal results in increased expression of GSTP1 protein
GSTP1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:9463521 PMID:11600134 PMID:15829614 PMID:18232660 PMID:19191707 More... NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtf2b general transcription factor IIB decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GTF2B mRNA CTD PMID:12419474 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
ISO POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLK protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLL protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV3L protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein] CTD PMID:22331492 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) decreases activity ISO 4-hydroxy-2-nonenal results in decreased activity of H6PD protein CTD PMID:20211231 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Haspin histone H3 associated protein kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HASPIN mRNA CTD PMID:19191707 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HBEGF mRNA CTD PMID:12419474 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HBP1 mRNA CTD PMID:19191707 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HCAR2 mRNA CTD PMID:19191707 NCBI chr12:32,726,334...32,727,416
Ensembl chr12:32,726,184...32,728,504
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HCK mRNA CTD PMID:19191707 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hdc histidine decarboxylase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HDC mRNA CTD PMID:19191707 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HELLS mRNA CTD PMID:19191707 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of HERC3 mRNA
4-hydroxy-2-nonenal results in decreased expression of HERC5 mRNA
CTD PMID:19191707 NCBI chr 4:87,952,202...88,042,492
Ensembl chr 4:87,952,274...88,042,488
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HGF mRNA CTD PMID:12419474 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HINT1 mRNA CTD PMID:12419474 NCBI chr10:38,989,516...38,993,259 JBrowse link
G Hivep2 HIVEP zinc finger 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HIVEP2 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
JBrowse link
G Hivep3 HIVEP zinc finger 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HIVEP3 mRNA CTD PMID:19191707 NCBI chr 5:133,325,327...133,727,797
Ensembl chr 5:133,658,052...133,727,795
JBrowse link
G Hlx H2.0-like homeobox decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HLX mRNA CTD PMID:19191707 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Hmga1 high mobility group AT-hook 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HMGA1 mRNA CTD PMID:12419474 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HMGA2 mRNA CTD PMID:19191707 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal analog results in increased expression of HMOX1; 4-hydroxy-2-nonenal results in increased expression of HMOX1; 4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA; 4-hydroxy-2-nonenal results in increased expression of HMOX1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; methyl-beta-cyclodextrin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]
4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]
CTD PMID:18232660 PMID:19191707 PMID:20638469 PMID:23845594 PMID:24291486 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HNF4A mRNA CTD PMID:12419474 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HPRT1 mRNA CTD PMID:19191707 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSD17B11 mRNA CTD PMID:19191707 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects binding EXP
ISO
4-hydroxy-2-nonenal binds to HSP90AA1 protein
4-hydroxy-2-nonenal analog binds to HSP90AA1
CTD PMID:18232660 PMID:21749116 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects binding EXP 4-hydroxy-2-nonenal binds to HSP90AB1 protein CTD PMID:21749116 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA1A CTD PMID:18232660
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPA1B mRNA CTD PMID:19191707 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA1L CTD PMID:18232660 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HSPA2 mRNA CTD PMID:12419474 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPA4L mRNA CTD PMID:19191707 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects binding
multiple interactions
increases expression
ISO
EXP
4-hydroxy-2-nonenal analog binds to HSPA5
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA]
4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA; 4-hydroxy-2-nonenal results in increased expression of HSPA5 protein
CTD PMID:18232660 PMID:24291486 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA9 CTD PMID:18232660 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPD1 CTD PMID:18232660 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPH1 mRNA CTD PMID:19191707 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HTATIP2 mRNA CTD PMID:19191707 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HUS1 mRNA CTD PMID:19191707 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ICAM1 mRNA CTD PMID:19191707 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ID1 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IDH1 mRNA CTD PMID:19191707 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IER3 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFI44L mRNA CTD PMID:19191707 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIH1 mRNA CTD PMID:19191707 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIT2 mRNA CTD PMID:19191707 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIT3 mRNA CTD PMID:19191707 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFITM2 mRNA CTD PMID:19191707 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:19627980 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Trichloroethylene co-treated with 4-hydroxy-2-nonenal analog] results in increased expression of IFNG protein CTD PMID:18267128 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IGF1 mRNA CTD PMID:19191707 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IGF1R mRNA CTD PMID:12419474 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IKBKE mRNA CTD PMID:19191707 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IKZF1 mRNA CTD PMID:19191707 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il10 interleukin 10 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL10 mRNA CTD PMID:19191707 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IL10RA mRNA CTD PMID:19191707 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL12RB1 mRNA CTD PMID:12419474 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL13RA1 mRNA CTD PMID:19191707 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681
JBrowse link
G Il17a interleukin 17A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL17A mRNA CTD PMID:12419474 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18rap interleukin 18 receptor accessory protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL18RAP mRNA CTD PMID:19191707 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1A mRNA CTD PMID:19191707 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1B mRNA CTD PMID:19191707 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1RL1 mRNA CTD PMID:19191707 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1RN mRNA CTD PMID:19191707 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Trichloroethylene co-treated with 4-hydroxy-2-nonenal analog] results in increased expression of IL2 protein CTD PMID:18267128 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il27 interleukin 27 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL27 mRNA CTD PMID:19191707 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il3 interleukin 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL3 mRNA CTD PMID:12419474 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il36a interleukin 36, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL36A mRNA CTD PMID:19191707 NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400
JBrowse link
G Il4r interleukin 4 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL4RA mRNA CTD PMID:19191707 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6 mRNA CTD PMID:19191707 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6R mRNA CTD PMID:12419474 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6ST mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Il7r interleukin 7 receptor decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of IL7R mRNA
4-hydroxy-2-nonenal results in increased expression of IL7R mRNA
CTD PMID:12419474 PMID:19191707 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Il9 interleukin 9 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL9 mRNA CTD PMID:12419474 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Impact impact RWD domain protein decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of IMPACT mRNA
4-hydroxy-2-nonenal results in increased expression of IMPACT mRNA
CTD PMID:19191707 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of INPPL1 mRNA CTD PMID:19191707 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Insig2 insulin induced gene 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of INSIG2 mRNA CTD PMID:19191707 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRAK3 mRNA CTD PMID:19191707 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein] CTD PMID:19627980 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRF7 mRNA CTD PMID:19191707 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irf8 interferon regulatory factor 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRF8 mRNA CTD PMID:19191707 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irgm immunity-related GTPase M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRGM mRNA CTD PMID:19191707 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ISG15 mRNA CTD PMID:19191707 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ISG20 mRNA CTD PMID:19191707 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA5 mRNA CTD PMID:12419474 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA6 mRNA CTD PMID:12419474 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itga7 integrin subunit alpha 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA7 mRNA CTD PMID:12419474 NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGAL mRNA CTD PMID:19191707 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGAM mRNA CTD PMID:19191707 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGB6 mRNA CTD PMID:12419474 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itsn1 intersectin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITSN1 mRNA CTD PMID:12419474 NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of JAK2 mRNA CTD PMID:19191707 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of JDP2 mRNA CTD PMID:19191707 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
increases phosphorylation
affects response to substance
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of JUN mRNA
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; 4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]
JUN protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]; 4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein]
CTD PMID:9890986 PMID:11488593 PMID:12419474 PMID:16322078 PMID:16337876 More... NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]] CTD PMID:9890986 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of JUND mRNA
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]]
CTD PMID:9890986 PMID:12419474 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of KAT8 mRNA CTD PMID:19191707 NCBI chr 1:182,524,355...182,536,638 JBrowse link
G Kdm6b lysine demethylase 6B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KDM6B mRNA CTD PMID:19191707 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KIF11 mRNA CTD PMID:19191707 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KIF20B mRNA CTD PMID:19191707 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kitlg KIT ligand increases expression ISO 4-hydroxy-2-nonenal results in increased expression of KITL mRNA CTD PMID:19191707 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf7 Kruppel like factor 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KLF7 mRNA CTD PMID:19191707 NCBI chr 9:65,437,535...65,484,720
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Klhl6 kelch-like family member 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KLHL6 mRNA CTD PMID:19191707 NCBI chr11:80,970,917...81,010,593
Ensembl chr11:80,970,917...81,009,677
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KPNA2 mRNA CTD PMID:19191707 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Lat linker for activation of T cells decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LAT mRNA CTD PMID:12419474 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LCAT mRNA CTD PMID:12419474 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LCK mRNA CTD PMID:12419474 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LIF mRNA CTD PMID:19191707 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LIPA mRNA CTD PMID:19191707 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LIPG mRNA CTD PMID:19191707 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G LOC100910669 paired immunoglobulin-like type 2 receptor alpha-like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PILRA mRNA CTD PMID:19191707 NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LPAR1 mRNA CTD PMID:19191707 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lpin1 lipin 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LPIN1 mRNA CTD PMID:19191707 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrrc59 leucine rich repeat containing 59 affects binding ISO LRRC59 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533
JBrowse link
G Lrrfip2 LRR binding FLII interacting protein 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LRRFIP2 mRNA CTD PMID:19191707 NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255
JBrowse link
G Ltb lymphotoxin beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LTB mRNA CTD PMID:19191707 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LY6E mRNA CTD PMID:19191707 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LY96 mRNA CTD PMID:19191707 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LYN mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAF1 mRNA CTD PMID:19191707 NCBI chr 7:108,075,173...108,078,252
Ensembl chr 7:108,075,189...108,078,249
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAFB mRNA CTD PMID:19191707 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAFG mRNA CTD PMID:19191707 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAP1LC3B mRNA CTD PMID:19191707 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAP2K5 mRNA CTD PMID:12419474 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAP3K20 mRNA CTD PMID:19191707 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases activity
multiple interactions
increases phosphorylation
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of MAPK1 protein
4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; 4-hydroxy-2-nonenal results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]; 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK1 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK1 protein
4-hydroxy-2-nonenal results in increased activity of and results in increased phosphorylation of MAPK1 protein
CTD PMID:16322078 PMID:17263905 PMID:23845594 PMID:24291486 PMID:24423726 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]
4-hydroxy-2-nonenal results in increased expression of MAPK14 mRNA
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]
CTD PMID:12684028 PMID:16322078 PMID:19191707 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases activity
multiple interactions
increases phosphorylation
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of MAPK3 protein
4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; 4-hydroxy-2-nonenal results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]; 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK3 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK3 protein
4-hydroxy-2-nonenal results in increased activity of and results in increased phosphorylation of MAPK3 protein
CTD PMID:16322078 PMID:17263905 PMID:23845594 PMID:24291486 PMID:24423726 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
increases phosphorylation
affects response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein
MAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein; GSTA4 protein inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein; Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]
CTD PMID:11488593 PMID:12684028 PMID:15064094 PMID:16322078 PMID:17263905 More... NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK9 protein CTD PMID:24825450 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Marcksl1 MARCKS-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MARCKSL1 mRNA CTD PMID:12419474 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MARK3 mRNA CTD PMID:12419474 NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MCM4 mRNA CTD PMID:12419474 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MCM6 mRNA CTD PMID:19191707 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) increases expression ISO 4-hydroxy-2-nonenal results in increased expression of METAP1D mRNA CTD PMID:19191707 NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MITF mRNA CTD PMID:23489423 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MKI67 mRNA CTD PMID:19191707 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MKNK1 mRNA CTD PMID:19191707 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mlh1 mutL homolog 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MLH1 mRNA CTD PMID:12419474 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases activity
increases expression
ISO 4-hydroxy-2-nonenal results in increased activity of MMP1 protein
4-hydroxy-2-nonenal results in increased expression of MMP1 mRNA
CTD PMID:14672615 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity
increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased activity of MMP2 protein
4-hydroxy-2-nonenal results in increased expression of MMP2 mRNA
1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2]; 4-hydroxy-2-nonenal results in increased expression of and results in increased secretion of and results in increased activity of MMP2 protein; AKT1 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2 protein]
CTD PMID:14672615 PMID:18805481 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
increases activity
multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of MMP9 mRNA
4-hydroxy-2-nonenal results in increased activity of MMP9 protein
ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; MK-886 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; U 75302 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]
4-hydroxy-2-nonenal results in increased expression of MMP9 mRNA; 4-hydroxy-2-nonenal results in increased expression of MMP9 protein
CTD PMID:19191707 PMID:19837106 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFI16 mRNA; 4-hydroxy-2-nonenal results in decreased expression of IFI204 mRNA
4-hydroxy-2-nonenal results in decreased expression of MNDA mRNA
CTD PMID:12419474 PMID:19191707 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
JBrowse link
G Mocos molybdenum cofactor sulfurase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MOCOS mRNA CTD PMID:19191707 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MOV10 mRNA CTD PMID:19191707 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MS4A6C mRNA CTD PMID:19191707 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MSH5 mRNA CTD PMID:19191707 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Mt1 metallothionein 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MT1 mRNA CTD PMID:20979157 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MT2 mRNA CTD PMID:19191707 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MTHFS mRNA CTD PMID:19191707 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
G Mtmr10 myotubularin related protein 10 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MTMR10 mRNA CTD PMID:19191707 NCBI chr 1:117,859,355...117,910,839
Ensembl chr 1:117,859,267...117,910,849
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MTOR mRNA CTD PMID:12419474 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MTSS1 mRNA CTD PMID:19191707 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mutyh mutY DNA glycosylase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MUTYH mRNA CTD PMID:19191707 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MX1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of MX2 mRNA CTD PMID:19191707 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mxd1 max dimerization protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MXD1 mRNA CTD PMID:19191707 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYBL2 mRNA CTD PMID:12419474 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYC mRNA CTD PMID:12419474 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYLK mRNA CTD PMID:12419474 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nab2 Ngfi-A binding protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NAB2 mRNA CTD PMID:19191707 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Napb NSF attachment protein beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NAPB mRNA CTD PMID:19191707 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345
JBrowse link
G Nbn nibrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NBN mRNA CTD PMID:12419474 PMID:19191707 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Nck1 NCK adaptor protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NCK1 mRNA CTD PMID:12419474 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NDC80 mRNA CTD PMID:19191707 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NECTIN1 mRNA CTD PMID:12419474 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
JBrowse link
G Neil3 nei-like DNA glycosylase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEIL3 mRNA CTD PMID:19191707 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of NEK2 mRNA
4-hydroxy-2-nonenal results in increased expression of NEK2 mRNA
CTD PMID:19191707 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nek3 NIMA-related kinase 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NEK3 mRNA CTD PMID:19191707 NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508
JBrowse link
G Nek6 NIMA-related kinase 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEK6 mRNA CTD PMID:19191707 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990
JBrowse link
G Neo1 neogenin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEO1 mRNA CTD PMID:12419474 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Nf2 neurofibromin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NF2 mRNA CTD PMID:12419474 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFAM1 mRNA CTD PMID:19191707 NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFATC1 mRNA CTD PMID:12419474 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFE2L1 mRNA CTD PMID:12419474 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases activity
multiple interactions
affects response to substance
affects localization
increases expression
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of NFE2L2 protein
AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal]
4-hydroxy-2-nonenal affects the localization of NFE2L2 protein
4-hydroxy-2-nonenal affects the localization of and results in increased activity of NFE2L2 protein; [GSTA4 protein mutant form results in decreased glutathionylation of 4-hydroxy-2-nonenal] which results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased activity of NFE2L2 protein]
4-hydroxy-2-nonenal results in increased expression of NFE2L2 protein
NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]
CTD PMID:16322078 PMID:19880816 PMID:24291486 PMID:24423726 PMID:24633890 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfic nuclear factor I/C increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFIC mRNA CTD PMID:19191707 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936
JBrowse link
G Nfix nuclear factor I X decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFIX mRNA CTD PMID:12419474 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of NFKB1 mRNA
4-hydroxy-2-nonenal results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; 4-hydroxy-2-nonenal results in decreased activity of [RELA protein binds to NFKB1 protein]
CTD PMID:11146106 PMID:12419474 PMID:19191707 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
4-hydroxy-2-nonenal results in increased expression of NFKBIA mRNA
CTD PMID:19191707 PMID:19627980 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFKBIE mRNA CTD PMID:19191707 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Nfkbiz NFKB inhibitor zeta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFKBIZ mRNA CTD PMID:19191707 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFRKB mRNA CTD PMID:12419474 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFX1 mRNA CTD PMID:12419474 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NKIRAS1 mRNA CTD PMID:19191707 NCBI chr15:7,492,806...7,503,828
Ensembl chr15:7,493,531...7,503,854
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRC4 mRNA CTD PMID:19191707 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRP10 mRNA CTD PMID:19191707 NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRP3 mRNA CTD PMID:19191707 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nmb neuromedin B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NMB mRNA CTD PMID:12419474 NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NME2 mRNA CTD PMID:12419474 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NOS2 protein CTD PMID:20940037 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NOTCH1 mRNA CTD PMID:19191707 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NQO1 mRNA
4-hydroxy-2-nonenal results in increased expression of NQO1 mRNA; 4-hydroxy-2-nonenal results in increased expression of NQO1 protein
CTD PMID:24423726 PMID:29108775 PMID:30849339 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR1D1 mRNA CTD PMID:19191707 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NR1D2 mRNA CTD PMID:19191707 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR1I3 mRNA CTD PMID:12419474 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR2F6 mRNA CTD PMID:12419474 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR3C1 mRNA CTD PMID:19191707 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR4A1 mRNA CTD PMID:19191707 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrp1 neuropilin 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NRP1 mRNA CTD PMID:19191707 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NSL1 mRNA CTD PMID:19191707 NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUF2 mRNA CTD PMID:19191707 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nufip1 nuclear FMR1 interacting protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUFIP1 mRNA CTD PMID:19191707 NCBI chr15:51,429,518...51,460,308
Ensembl chr15:51,429,549...51,460,310
JBrowse link
G Nup210 nucleoporin 210 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NUP210 mRNA CTD PMID:19191707 NCBI chr 4:123,511,559...123,609,874
Ensembl chr 4:123,511,559...123,609,874
JBrowse link
G Nup85 nucleoporin 85 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NUP85 mRNA CTD PMID:19191707 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUSAP1 mRNA CTD PMID:19191707 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of OAS3 mRNA CTD PMID:19191707 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
JBrowse link
G Olr1271 olfactory receptor 1271 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of OLFR933 mRNA CTD PMID:19191707 NCBI chr 8:39,127,409...39,131,889
Ensembl chr 8:39,127,352...39,131,900
JBrowse link
G Osm oncostatin M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of OSM mRNA CTD PMID:19191707 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G P2rx5 purinergic receptor P2X 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of P2RX5 mRNA CTD PMID:12419474 NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of P2RY2 mRNA CTD PMID:19191707 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta affects metabolic processing EXP 4-hydroxy-2-nonenal affects the metabolism of P4HB protein CTD PMID:16097806 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PA2G4 mRNA CTD PMID:19191707 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PAIP1 mRNA CTD PMID:12419474 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases degradation ISO 4-hydroxy-2-nonenal results in increased degradation of PARP1 protein CTD PMID:11488593 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp12 poly (ADP-ribose) polymerase family, member 12 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PARP12 mRNA CTD PMID:19191707 NCBI chr 4:67,826,548...67,885,356
Ensembl chr 4:67,839,237...67,883,685
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PBK mRNA CTD PMID:19191707 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pcgf5 polycomb group ring finger 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PCGF5 mRNA CTD PMID:19191707 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PCNA mRNA CTD PMID:19191707 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PCSK2 mRNA CTD PMID:12419474 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pcyox1 prenylcysteine oxidase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PCYOX1 mRNA CTD PMID:19191707 NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PDCD4 mRNA CTD PMID:19191707 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PDGFB mRNA CTD PMID:19191707 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects binding ISO 4-hydroxy-2-nonenal analog binds to PDIA3 CTD PMID:18232660 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PDSS1 mRNA CTD PMID:19191707 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Pdyn prodynorphin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PDYN mRNA CTD PMID:12419474 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Penk proenkephalin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PENK mRNA CTD PMID:19191707 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per1 period circadian regulator 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PER1 mRNA CTD PMID:19191707 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pex7 peroxisomal biogenesis factor 7 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PEX7 mRNA CTD PMID:19191707 NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGD mRNA CTD PMID:19191707 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGLYRP3 mRNA CTD PMID:19191707 NCBI chr 2:177,479,693...177,490,867
Ensembl chr 2:176,855,732...176,874,162
Ensembl chr 2:176,855,732...176,874,162
JBrowse link
G Pgm2l1 phosphoglucomutase 2-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGM2L1 mRNA CTD PMID:19191707 NCBI chr 1:154,571,410...154,620,902
Ensembl chr 1:154,571,766...154,620,902
JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PGS1 mRNA CTD PMID:19191707 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254
JBrowse link
G Phb prohibitin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHB mRNA CTD PMID:12419474 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phf11 PHD finger protein 11 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHF11 mRNA CTD PMID:19191707 NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
JBrowse link
G Phf21a PHD finger protein 21A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PHF21A mRNA CTD PMID:19191707 NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865
JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects binding ISO PHGDH protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHLDA1 mRNA CTD PMID:19191707 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PIK3CB mRNA CTD PMID:19191707 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PIK3CD mRNA CTD PMID:19191707 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PIK3R2 mRNA CTD PMID:12419474 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PILRA mRNA CTD PMID:19191707
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 affects binding
increases response to substance
ISO 4-hydroxy-2-nonenal binds to PIN1 protein
PIN1 protein results in increased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:23231502 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Pkm pyruvate kinase M1/2 affects binding
multiple interactions
ISO 4-hydroxy-2-nonenal analog binds to PKM protein
4-hydroxy-2-nonenal binds to and results in decreased activity of PKM protein; 4-hydroxy-2-nonenal promotes the reaction [PKM protein binds to PKM protein]
CTD PMID:27978618 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLA2G7 mRNA CTD PMID:19191707 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PLAGL2 mRNA CTD PMID:19191707 NCBI chr 3:141,695,322...141,708,567
Ensembl chr 3:141,695,322...141,708,503
JBrowse link
G Pld2 phospholipase D2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLD2 mRNA CTD PMID:19191707 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLEKHM1 mRNA CTD PMID:19191707 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of PLEKHO1 mRNA
4-hydroxy-2-nonenal results in increased expression of PLEKHO1 mRNA
CTD PMID:19191707 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PLK1 mRNA CTD PMID:19191707 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLK2 mRNA CTD PMID:19191707 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Polb DNA polymerase beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLB mRNA CTD PMID:12419474 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLD1 mRNA CTD PMID:12419474 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit increases expression ISO 4-hydroxy-2-nonenal results in increased expression of POLE mRNA CTD PMID:19191707 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
JBrowse link
G Polh DNA polymerase eta multiple interactions
affects response to substance
ISO POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
POLH protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723
JBrowse link
G Polk DNA polymerase kappa multiple interactions ISO POLK protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein] CTD PMID:22331492 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Poll DNA polymerase lambda affects response to substance
multiple interactions
ISO POLL protein affects the susceptibility to 4-hydroxy-2-nonenal
POLL protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
CTD PMID:22331492 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
JBrowse link
G Polq DNA polymerase theta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLQ mRNA CTD PMID:19191707 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
ISO 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
4-hydroxy-2-nonenal results in decreased activity of PON1 protein
CTD PMID:15375178 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pou2f2 POU class 2 homeobox 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POU2F2 mRNA CTD PMID:19191707 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPARG protein CTD PMID:27417252 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppid peptidylprolyl isomerase D increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PPID mRNA CTD PMID:19191707 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PPIL1 mRNA CTD PMID:19191707 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP1CA mRNA CTD PMID:12419474 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA]
CTD PMID:24291486 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP1R15B mRNA CTD PMID:19191707 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP3CA mRNA CTD PMID:12419474 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PRDM1 mRNA CTD PMID:12419474 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prdx1 peroxiredoxin 1 affects binding
increases expression
ISO 4-hydroxy-2-nonenal analog binds to PRDX1
4-hydroxy-2-nonenal results in increased expression of PRDX1 mRNA
CTD PMID:18232660 PMID:19191707 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PRKDC mRNA CTD PMID:12419474 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Procr protein C receptor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PROCR mRNA CTD PMID:19191707 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PSMB10 mRNA CTD PMID:19191707 NCBI chr19:33,830,958...33,833,442 JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PSMC3IP mRNA CTD PMID:19191707 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PSMD12 mRNA CTD PMID:19191707 NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTGER4 mRNA CTD PMID:19191707 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptges prostaglandin E synthase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PTGES mRNA CTD PMID:19191707 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions
decreases response to substance
EXP [PTGR1 protein co-treated with NADP] affects the reduction of 4-hydroxy-2-nonenal
PTGR1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:11524419 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTK2 mRNA CTD PMID:12419474 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTPN1 mRNA CTD PMID:12419474 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PTPRA mRNA CTD PMID:19191707 NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728
JBrowse link
G Pxk PX domain containing serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PXK mRNA CTD PMID:19191707 NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444
JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAB11A mRNA CTD PMID:19191707 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RABGEF1 mRNA CTD PMID:19191707 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAD23A mRNA CTD PMID:19191707 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of RAD51 mRNA
4-hydroxy-2-nonenal results in increased expression of RAD51 mRNA
CTD PMID:19191707 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad54l RAD54 like decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RAD54L mRNA CTD PMID:19191707 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Raet1e retinoic acid early transcript 1E increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAET1E mRNA CTD PMID:19191707 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAF1 mRNA CTD PMID:19191707 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Ralbp1 ralA binding protein 1 decreases response to substance ISO RALBP1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal CTD PMID:15950949 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RALGDS mRNA CTD PMID:12419474 NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059
JBrowse link
G Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RALGPS1 mRNA CTD PMID:19191707 NCBI chr 3:16,433,323...16,670,276
Ensembl chr 3:16,433,742...16,669,972
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RARA mRNA CTD PMID:19191707 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RARB mRNA CTD PMID:12419474 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rasgef1b RasGEF domain family, member 1B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RASGEF1B mRNA CTD PMID:19191707 NCBI chr14:9,859,512...10,380,044
Ensembl chr14:9,860,247...10,379,741
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RASGRP3 mRNA CTD PMID:19191707 NCBI chr 6:19,895,366...19,993,945
Ensembl chr 6:19,895,390...19,958,578
JBrowse link
G Rassf2 Ras association domain family member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RASSF2 mRNA CTD PMID:19191707 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
JBrowse link
G Rassf8 Ras association domain family member 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RASSF8 mRNA CTD PMID:19191707 NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO 4-hydroxy-2-nonenal results in decreased phosphorylation of RB1 protein CTD PMID:15607904 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RBL1 mRNA CTD PMID:19191707 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RBL2 mRNA CTD PMID:12419474 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of REL mRNA CTD PMID:12419474 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 4-hydroxy-2-nonenal results in decreased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11146106 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rev1 REV1, DNA directed polymerase multiple interactions
affects response to substance
ISO REV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
REV1 protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit multiple interactions
affects response to substance
ISO REV3L protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
REV3L protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RFFL mRNA CTD PMID:19191707 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rgs1 regulator of G-protein signaling 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RGS1 mRNA CTD PMID:19191707 NCBI chr13:56,018,529...56,022,939
Ensembl chr13:56,018,554...56,022,984
JBrowse link
G Riok3 RIO kinase 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RIOK3 mRNA CTD PMID:19191707 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RIT1 mRNA CTD PMID:19191707 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RND1 mRNA CTD PMID:19191707 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
JBrowse link
G Rnf128 ring finger protein 128 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RNF128 mRNA CTD PMID:19191707 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423
JBrowse link
G Rnf167 ring finger protein 167 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RNF167 mRNA CTD PMID:19191707 NCBI chr10:55,360,603...55,364,927
Ensembl chr10:55,360,543...55,364,927
JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RNF19B mRNA CTD PMID:19191707 NCBI chr 5:141,406,085...141,431,380
Ensembl chr 5:141,406,118...141,431,380
JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RPP38 mRNA CTD PMID:19191707 NCBI chr17:74,914,066...74,917,742
Ensembl chr17:74,908,932...74,927,431
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RPS6KA2 mRNA CTD PMID:12419474 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation EXP 4-hydroxy-2-nonenal results in increased phosphorylation of RPS6KB1 protein CTD PMID:19289642 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RSAD2 mRNA CTD PMID:19191707 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-DMb RT1 class II, locus DMb decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of H2-DMB2 mRNA CTD PMID:19191707 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of H2-T23 mRNA CTD PMID:19191707 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RXRA mRNA CTD PMID:19191707 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RXRB mRNA CTD PMID:12419474 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of S1PR2 mRNA CTD PMID:19191707 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 affects binding ISO SAMHD1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SAMSN1 mRNA CTD PMID:19191707 NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900
JBrowse link
G Sass6 SAS-6 centriolar assembly protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SASS6 mRNA CTD PMID:19191707 NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SATB1 mRNA CTD PMID:12419474 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Sbno2 strawberry notch homolog 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SBNO2 mRNA CTD PMID:19191707 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
affects binding
ISO Tobacco Smoke Pollution promotes the reaction [4-hydroxy-2-nonenal binds to SCARB1 protein] CTD PMID:22442701 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SELENBP1 mRNA CTD PMID:12419474
G Serbp1 Serpine1 mRNA binding protein 1 affects binding ISO SERBP1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
JBrowse link
G Serpinb5 serpin family B member 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SERPINB5 mRNA CTD PMID:12419474 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SERPINB9 mRNA CTD PMID:19191707 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SERPINI1 mRNA CTD PMID:12419474 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
JBrowse link
G Sesn2 sestrin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SESN2 mRNA CTD PMID:19191707 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGK1 mRNA CTD PMID:19191707 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGO1 mRNA CTD PMID:19191707 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805
JBrowse link
G Sgo2 shugoshin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGO2 mRNA CTD PMID:19191707 NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SGPL1 mRNA CTD PMID:19191707 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Shoc2 SHOC2 leucine-rich repeat scaffold protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SHOC2 mRNA CTD PMID:12419474 NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO SIRT1 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal] CTD PMID:24633890 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO 4-hydroxy-2-nonenal binds to and results in decreased activity of SIRT3 protein CTD PMID:21449565 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc25a27 solute carrier family 25, member 27 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SLC25A27 mRNA CTD PMID:20385226 NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [APC protein mutant form results in increased expression of SLC7A11 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal CTD PMID:21967605 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SLC7A2 mRNA CTD PMID:19191707 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
JBrowse link
G Smad1 SMAD family member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SMAD1 mRNA CTD PMID:12419474 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SMC4 mRNA CTD PMID:19191707 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Snapc5 small nuclear RNA activating complex, polypeptide 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SNAPC5 mRNA CTD PMID:19191707 NCBI chr 8:64,677,204...64,680,769
Ensembl chr 8:64,677,205...64,681,964
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SOCS3 mRNA CTD PMID:19191707 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 affects binding
increases abundance
multiple interactions
decreases abundance
increases expression
ISO 4-hydroxy-2-nonenal binds to SOD2 protein
SOD2 gene mutant form results in increased abundance of 4-hydroxy-2-nonenal
SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]
SOD2 protein results in decreased abundance of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased expression of SOD2 mRNA
CTD PMID:11507057 PMID:19191707 PMID:19374891 PMID:23199288 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp100 SP100 nuclear antigen decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP100 mRNA CTD PMID:19191707 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Sp110 SP110 nuclear body protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP110 mRNA CTD PMID:19191707 NCBI chr 9:86,200,503...86,225,355
Ensembl chr 9:86,200,503...86,222,670
JBrowse link
G Sp2 Sp2 transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP2 mRNA CTD PMID:12419474 NCBI chr10:81,940,580...81,970,548
Ensembl chr10:81,940,587...81,970,548
JBrowse link
G Spa17 sperm autoantigenic protein 17 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SPA17 mRNA CTD PMID:19191707 NCBI chr 8:37,307,432...37,318,645
Ensembl chr 8:37,307,557...37,318,639
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPAG5 mRNA CTD PMID:19191707 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPRY1 mRNA CTD PMID:19191707 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPRY2 mRNA CTD PMID:12419474 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA CTD PMID:19191707 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SRC mRNA CTD PMID:19191707 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srp9 signal recognition particle 9 affects binding ISO SRP9 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720
JBrowse link
G Srpk2 SRSF protein kinase 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SRPK2 mRNA CTD PMID:19191707 NCBI chr 4:11,464,684...11,655,993
Ensembl chr 4:11,464,674...11,655,990