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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxyaldehyde
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Accession:CHEBI:50413 term browser browse the term
Synonyms:related_synonym: hydroxyaldehydes
 alt_id: CHEBI:24671;   CHEBI:5798
 xref: KEGG:C06461


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4-hydroxynon-2-enal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ABCA1 mRNA CTD PMID:19191707 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects binding
increases expression
multiple interactions
ISO 4-hydroxy-2-nonenal binds to ABCC1 protein
4-hydroxy-2-nonenal results in increased expression of ABCC1 mRNA
[GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:15672542, PMID:19191707, PMID:21925487 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
EXP
ISO
ABCC2 protein affects the export of 4-hydroxy-2-nonenal metabolite
4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]
CTD PMID:12623073, PMID:19326901 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle affects binding EXP 4-hydroxy-2-nonenal binds to ACTA1 protein CTD PMID:15886073 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Actb actin, beta affects binding ISO ACTB protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actn1 actinin, alpha 1 affects binding ISO ACTN1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 affects binding ISO ACTN4 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADH7 mRNA CTD PMID:19191707 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Adi1 acireductone dioxygenase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADI1 mRNA CTD PMID:19191707 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ADORA1 mRNA CTD PMID:12419474 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2b adenosine A2B receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ADORA2B mRNA CTD PMID:19191707 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ADRB2 mRNA CTD PMID:19191707 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ago2 argonaute RISC catalytic component 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AGO2 mRNA CTD PMID:19191707 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Ago3 argonaute RISC catalytic component 3 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of AGO3 mRNA
4-hydroxy-2-nonenal results in increased expression of AGO3 mRNA
CTD PMID:19191707 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Agrn agrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AGRN mRNA CTD PMID:19191707 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Agt angiotensinogen affects binding
multiple interactions
ISO 4-hydroxy-2-nonenal binds to AGT protein modified form; AGT protein modified form binds to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal binds to and results in increased lipidation of AGT protein modified form; [AGT protein modified form results in increased chemical synthesis of Lipid Peroxides] which results in increased abundance of 4-hydroxy-2-nonenal; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]
CTD PMID:20977208, PMID:26111765, PMID:31144504 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AHSA2 mRNA CTD PMID:19191707 NCBI chr14:108,262,795...108,274,000
Ensembl chr14:108,265,207...108,273,938
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AIFM1 mRNA CTD PMID:19191707 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akna AT-hook transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AKNA mRNA CTD PMID:19191707 NCBI chr 5:79,184,087...79,232,370
Ensembl chr 5:79,184,088...79,222,687
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction
increases expression
ISO AKR1A1 protein results in increased reduction of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased expression of AKR1A1 mRNA
CTD PMID:10510318, PMID:19191707 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B affects reduction
increases reduction
ISO AKR1B1 protein affects the reduction of 4-hydroxy-2-nonenal
AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal; AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal metabolite
CTD PMID:9890881, PMID:10510318, PMID:11306073, PMID:21329684 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
increases metabolic processing
ISO AKR1B10 protein results in increased reduction of 4-hydroxy-2-nonenal
Oleanolic Acid inhibits the reaction [AKR1B10 protein results in increased metabolism of 4-hydroxy-2-nonenal]
CTD PMID:19013440, PMID:21329684, PMID:27417252 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 4-hydroxy-2-nonenal CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
increases response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in increased expression of AKR1C3 mRNA; 4-hydroxy-2-nonenal results in increased expression of AKR1C3 protein
AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal
7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal]
CTD PMID:22964423, PMID:30849339 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases response to substance
affects response to substance
increases response to substance
multiple interactions
increases expression
ISO AKR7A2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
AKR7A2 protein affects the susceptibility to 4-hydroxy-2-nonenal
AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal
7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal]; AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal]
4-hydroxy-2-nonenal results in increased expression of AKR7A2 mRNA; 4-hydroxy-2-nonenal results in increased expression of AKR7A2 protein
CTD PMID:22001351, PMID:22964423, PMID:30849339 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects response to substance
decreases phosphorylation
increases activity
multiple interactions
EXP
ISO
AKT1 protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in decreased phosphorylation of AKT1 protein
4-hydroxy-2-nonenal results in increased activity of AKT1 protein
AKT1 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2 protein]
CTD PMID:18805481, PMID:23845594, PMID:24825450 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases metabolic processing
increases oxidation
multiple interactions
ISO ALDH1A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH1A1 protein results in increased oxidation of 4-hydroxy-2-nonenal
[APC protein mutant form results in increased expression of ALDH1A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:21256123, PMID:21967605, PMID:22339434 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions
increases oxidation
ISO [APC protein mutant form results in increased expression of ALDH2 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
ALDH2 protein results in increased oxidation of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal binds to and results in decreased activity of ALDH2 protein; ALDH2 protein inhibits the reaction [Rotenone results in increased abundance of 4-hydroxy-2-nonenal]
CTD PMID:21967605, PMID:22339434, PMID:25263579 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases response to substance
increases oxidation
multiple interactions
increases metabolic processing
affects response to substance
affects metabolic processing
ISO
EXP
ALDH3A1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
ALDH3A1 protein results in increased oxidation of 4-hydroxy-2-nonenal
[APC protein mutant form results in increased expression of ALDH3A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
ALDH3A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH3A1 protein affects the susceptibility to 4-hydroxy-2-nonenal
ALDH3A1 protein affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:11018474, PMID:11306050, PMID:15905174, PMID:21256123, PMID:21967605, PMID:22339434 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding
decreases response to substance
ISO 4-hydroxy-2-nonenal binds to ALDH3B1 protein
ALDH3B1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:20699116 NCBI chr 1:219,145,457...219,181,536
Ensembl chr 1:219,145,459...219,186,860
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALDH6A1 mRNA CTD PMID:19191707 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 increases metabolic processing
decreases response to substance
ISO ALDH7A1 protein results in increased metabolism of 4-hydroxy-2-nonenal
ALDH7A1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:21338592 NCBI chr18:51,619,007...51,651,267
Ensembl chr18:51,619,007...51,651,267
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A affects binding ISO ALDOA protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein] CTD PMID:19837106 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALOX5AP mRNA CTD PMID:19191707 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Alpk1 alpha-kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ALPK1 mRNA CTD PMID:19191707 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ALS2 mRNA CTD PMID:19191707 NCBI chr 9:65,961,361...66,034,396
Ensembl chr 9:65,961,346...66,033,871
JBrowse link
G Amph amphiphysin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AMPH mRNA CTD PMID:12419474 NCBI chr17:48,304,324...48,562,838
Ensembl chr17:48,304,322...48,562,905
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ANLN mRNA CTD PMID:19191707 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ANP32A mRNA CTD PMID:19191707 NCBI chr 8:67,295,578...67,333,075
Ensembl chr 8:67,295,727...67,333,247
JBrowse link
G Aoah acyloxyacyl hydrolase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AOAH mRNA CTD PMID:19191707 NCBI chr17:45,872,414...46,115,026
Ensembl chr17:45,872,414...46,115,004
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of AOX1 mRNA CTD PMID:19191707 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AP1S3 mRNA CTD PMID:19191707 NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
affects oxidation
affects response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of APC mRNA
APC protein affects the oxidation of 4-hydroxy-2-nonenal
APC protein affects the susceptibility to 4-hydroxy-2-nonenal
[APC protein affects the oxidation of 4-hydroxy-2-nonenal] which affects the abundance of 4-hydroxynonenoic acid; [APC protein mutant form results in increased expression of ALDH1A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of ALDH2 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of ALDH3A1 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of GSTA4 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal; [APC protein mutant form results in increased expression of SLC7A11 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal
CTD PMID:12419474, PMID:21967605 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of APEX1 mRNA CTD PMID:19191707 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa1 apolipoprotein A1 affects binding ISO 4-hydroxy-2-nonenal binds to APOA1 protein CTD PMID:18778096 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apod apolipoprotein D decreases abundance ISO APOD protein results in decreased abundance of 4-hydroxy-2-nonenal CTD PMID:28182653 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of APP mRNA
[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]
CTD PMID:12419474, PMID:17964426 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGAP11A mRNA CTD PMID:19191707 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARHGAP22 mRNA CTD PMID:19191707 NCBI chr16:9,454,269...9,613,508
Ensembl chr16:9,486,832...9,613,528
JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARHGAP27 mRNA CTD PMID:19191707 NCBI chr10:91,418,535...91,451,831
Ensembl chr10:91,419,912...91,448,477
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGAP5 mRNA CTD PMID:12419474 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGDIA mRNA CTD PMID:12419474 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARHGEF3 mRNA CTD PMID:19191707 NCBI chr16:2,743,714...3,026,768
Ensembl chr16:2,743,823...3,026,760
JBrowse link
G Arid5a AT-rich interaction domain 5A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ARID5A mRNA CTD PMID:19191707 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ARRDC3 mRNA CTD PMID:19191707 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of ASF1B mRNA
4-hydroxy-2-nonenal results in increased expression of ASF1B mRNA
CTD PMID:19191707 NCBI chr19:25,077,918...25,092,491
Ensembl chr19:25,077,918...25,092,491
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ASPM mRNA CTD PMID:19191707 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ATAD5 mRNA CTD PMID:19191707 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATF3 protein CTD PMID:19041636 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of ATF4 mRNA; 4-hydroxy-2-nonenal results in increased expression of ATF4 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein]
CTD PMID:24291486 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form]
CTD PMID:24291486 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATM mRNA CTD PMID:19191707 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ATP1B3 mRNA CTD PMID:12419474 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects binding ISO 4-hydroxy-2-nonenal binds to ATP5F1A protein CTD PMID:19374891 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ATP6V1A mRNA CTD PMID:19191707 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atr ATR serine/threonine kinase decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of ATR mRNA
4-hydroxy-2-nonenal results in increased expression of ATR mRNA
CTD PMID:12419474, PMID:19191707 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Avil advillin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AVIL mRNA CTD PMID:19191707 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of B2M mRNA CTD PMID:19191707 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BABAM2 mRNA CTD PMID:19191707 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of BAD mRNA
4-hydroxy-2-nonenal results in increased expression of BAD protein
CTD PMID:12419474, PMID:24825450 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Batf2 basic leucine zipper ATF-like transcription factor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BATF2 mRNA CTD PMID:19191707 NCBI chr 1:221,538,006...221,546,650
Ensembl chr 1:221,538,104...221,545,782
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of BAX mRNA
4-hydroxy-2-nonenal results in increased expression of BAX protein
CTD PMID:12419474, PMID:15607904, PMID:21187080, PMID:24825450 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
EXP 4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA] CTD PMID:24291486 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bbx BBX high mobility group box domain containing increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BBX mRNA CTD PMID:19191707 NCBI chr11:52,983,286...53,228,557
Ensembl chr11:53,081,025...53,228,716
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCAR3 mRNA CTD PMID:19191707 NCBI chr 2:226,563,050...226,679,449
Ensembl chr 2:226,563,050...226,679,438
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL2A1B mRNA CTD PMID:19191707 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL2L1 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BCL2L11 mRNA CTD PMID:19191707 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BCL3 mRNA CTD PMID:19191707 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BCL6 mRNA CTD PMID:19191707 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA
CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA]
CTD PMID:16337876 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BHLHE40 mRNA CTD PMID:19191707 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BHLHE41 mRNA CTD PMID:19191707 NCBI chr 4:180,230,742...180,235,138
Ensembl chr 4:180,232,382...180,234,804
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BID mRNA CTD PMID:19191707 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of BIRC5 mRNA
4-hydroxy-2-nonenal results in decreased expression of BIRC5 mRNA
CTD PMID:19191707 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BLM mRNA CTD PMID:19191707 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BLVRB mRNA CTD PMID:19191707 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BMP1 mRNA CTD PMID:12419474 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BNIP3 mRNA CTD PMID:12419474 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BRAF mRNA CTD PMID:12419474 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BUB1 mRNA CTD PMID:19191707 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of BUB1B mRNA CTD PMID:19191707 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of BZW1 mRNA CTD PMID:19191707 NCBI chr 9:65,279,675...65,293,471
Ensembl chr 9:65,279,675...65,291,651
JBrowse link
G C5ar1 complement C5a receptor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of C5AR1 mRNA CTD PMID:19191707 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAR12 mRNA CTD PMID:19191707 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CACNA1A mRNA CTD PMID:19191707 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cadps calcium dependent secretion activator increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CADPS mRNA CTD PMID:19191707 NCBI chr15:15,275,489...15,690,575
Ensembl chr15:15,275,541...15,667,778
JBrowse link
G Calca calcitonin-related polypeptide alpha increases secretion EXP 4-hydroxy-2-nonenal results in increased secretion of CALCA protein CTD PMID:17684094 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CALCOCO1 mRNA CTD PMID:19191707 NCBI chr 7:144,307,562...144,322,253
Ensembl chr 7:144,307,509...144,322,240
JBrowse link
G Calr3 calreticulin 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CALR3 mRNA CTD PMID:19191707 NCBI chr16:19,097,391...19,124,062
Ensembl chr16:19,097,391...19,124,062
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAMK1D mRNA CTD PMID:19191707 NCBI chr17:76,532,611...76,938,956
Ensembl chr17:76,532,611...76,938,956
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 affects binding ISO CAP1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capn2 calpain 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CAPN2 mRNA CTD PMID:12419474 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CAPNS1 mRNA CTD PMID:12419474 NCBI chr 1:91,058,528...91,064,880 JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta affects binding ISO CAPZB protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Car2 carbonic anhydrase 2 affects binding ISO CA2 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CARHSP1 mRNA CTD PMID:19191707 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASK mRNA CTD PMID:12419474 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp1 caspase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP1 mRNA CTD PMID:19191707 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
ISO
EXP
4-hydroxy-2-nonenal results in increased cleavage of and results in increased activity of CASP3 protein; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]
4-hydroxy-2-nonenal results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]
CTD PMID:11488593, PMID:16322078, PMID:16337876, PMID:17263905, PMID:19326901, PMID:20114059, PMID:21187080, PMID:24291486, PMID:24825450 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP4 mRNA CTD PMID:19191707 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP7 mRNA CTD PMID:19191707 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CASP8 mRNA CTD PMID:12419474 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased activity of CASP9 protein
pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP9 protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP9 protein]
CTD PMID:16322078, PMID:17263905, PMID:21187080, PMID:24825450 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CAT mRNA CTD PMID:19191707, PMID:24423726 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CBLB mRNA CTD PMID:12419474 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CCL17 mRNA
4-hydroxy-2-nonenal results in increased expression of CCL17 mRNA
CTD PMID:19191707 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL2 mRNA CTD PMID:19191707 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL22 mRNA CTD PMID:19191707 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL3 mRNA CTD PMID:12419474 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL4 mRNA CTD PMID:19191707 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression
ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein]
4-hydroxy-2-nonenal results in decreased expression of CCL5 mRNA
CTD PMID:19191707, PMID:19627980 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL6 mRNA CTD PMID:19191707 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCL7 mRNA CTD PMID:19191707 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNA2 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNB1 mRNA CTD PMID:19191707 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of CCND1]
4-hydroxy-2-nonenal results in increased expression of CCND1; 4-hydroxy-2-nonenal results in increased expression of CCND1 mRNA
CTD PMID:16328008, PMID:19191707 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCND2 protein CTD PMID:15607904 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnf cyclin F decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNF mRNA CTD PMID:19191707 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccng1 cyclin G1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CCNG1 mRNA CTD PMID:19191707 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNG2 mRNA CTD PMID:19191707 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccnk cyclin K decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNK mRNA CTD PMID:12419474 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Ccnt1 cyclin T1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCNT1 mRNA CTD PMID:12419474 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CCR1 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd14 CD14 molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD14 mRNA CTD PMID:19191707 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd300a Cd300a molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD300A mRNA CTD PMID:19191707 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Cd300lb CD300 molecule-like family member b increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD300LB mRNA CTD PMID:19191707 NCBI chr10:103,471,082...103,481,071
Ensembl chr10:103,467,725...103,481,153
JBrowse link
G Cd300lf Cd300 molecule-like family member F decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD300LF mRNA CTD PMID:19191707 NCBI chr10:103,669,781...103,690,584
Ensembl chr10:103,670,028...103,687,425
JBrowse link
G Cd36 CD36 molecule increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CD36 mRNA CTD PMID:19191707 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40 CD40 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD40 mRNA CTD PMID:19191707 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD44 mRNA CTD PMID:19191707 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD47 mRNA CTD PMID:12419474 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd83 CD83 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD83 mRNA CTD PMID:19191707 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CD86 mRNA CTD PMID:19191707 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC20 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC25A mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDC25C mRNA CTD PMID:19191707 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDCA2 mRNA CTD PMID:19191707 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDH2 mRNA CTD PMID:12419474 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh3 cadherin 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDH3 mRNA CTD PMID:12419474 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO 4-hydroxy-2-nonenal binds to and results in increased alkylation of and results in decreased activity of CDK2 protein CTD PMID:26910110 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CDK6 mRNA CTD PMID:19191707 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDK9 mRNA CTD PMID:12419474 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CDKN1A protein CTD PMID:15607904 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CDKN1C mRNA CTD PMID:12419474 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CEBPA mRNA CTD PMID:19191707 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cenpa centromere protein A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CENPA mRNA CTD PMID:19191707 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CEP290 mRNA CTD PMID:19191707 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Ces1d carboxylesterase 1D decreases activity ISO 4-hydroxy-2-nonenal results in decreased activity of CES1 protein CTD PMID:21878322 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H increases activity ISO 4-hydroxy-2-nonenal results in increased activity of CES2 protein CTD PMID:21878322 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfb complement factor B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CFB mRNA CTD PMID:19191707 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfl1 cofilin 1 affects binding ISO CFL1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CHEK1 mRNA CTD PMID:19191707 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chml CHM like Rab escort protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CHML mRNA CTD PMID:19191707 NCBI chr13:93,740,759...93,742,624 JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CILK1 mRNA CTD PMID:19191707 NCBI chr 8:85,413,998...85,473,374
Ensembl chr 8:85,413,537...85,472,694
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CISH mRNA CTD PMID:19191707 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CKS1B mRNA CTD PMID:19191707 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CKS2 mRNA CTD PMID:19191707 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn11 claudin 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CLDN11 mRNA CTD PMID:19191707 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clec12a C-type lectin domain family 12, member A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC12A mRNA CTD PMID:19191707 NCBI chr 4:163,112,100...163,130,979
Ensembl chr 4:163,112,301...163,126,864
JBrowse link
G Clec2d C-type lectin domain family 2, member D decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC2D mRNA CTD PMID:19191707 NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CLEC4D mRNA CTD PMID:19191707 NCBI chr 4:156,253,084...156,264,766
Ensembl chr 4:156,253,079...156,264,769
JBrowse link
G Clec5a C-type lectin domain containing 5A decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CLEC5A mRNA
4-hydroxy-2-nonenal results in increased expression of CLEC5A mRNA
CTD PMID:19191707 NCBI chr 4:68,810,330...68,819,921
Ensembl chr 4:68,808,359...68,819,928
JBrowse link
G Clk3 CDC-like kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CLK3 mRNA CTD PMID:12419474 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO 4-hydroxy-2-nonenal results in increased expression of COL1A1 mRNA; 4-hydroxy-2-nonenal results in increased expression of COL1A1 protein CTD PMID:14672615 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Comt catechol-O-methyltransferase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of COMT mRNA CTD PMID:12419474 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cp ceruloplasmin decreases expression
affects abundance
ISO 4-hydroxy-2-nonenal results in decreased expression of CP mRNA
CP protein affects the abundance of 4-hydroxy-2-nonenal
CTD PMID:12572680, PMID:19191707 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpe carboxypeptidase E decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CPE mRNA CTD PMID:12419474 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression
increases phosphorylation
ISO 4-hydroxy-2-nonenal results in decreased expression of CREB1 mRNA
4-hydroxy-2-nonenal results in increased phosphorylation of CREB1 protein
CTD PMID:12419474, PMID:16337876 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crebbp CREB binding protein multiple interactions EXP CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA] CTD PMID:16337876 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CREG1 mRNA CTD PMID:19191707 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CROT mRNA CTD PMID:19191707 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRY1 mRNA CTD PMID:19191707 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRY2 mRNA CTD PMID:19191707 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Cryz crystallin zeta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CRYZ mRNA CTD PMID:12419474 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CSF1R mRNA CTD PMID:19191707 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CSF2 mRNA CTD PMID:19191707 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of CSF3 mRNA
4-hydroxy-2-nonenal results in increased expression of CSF3 mRNA; 4-hydroxy-2-nonenal results in increased expression of CSF3 protein
CTD PMID:19191707 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CSNK1G2 mRNA CTD PMID:12419474 NCBI chr 7:11,944,957...11,963,268
Ensembl chr 7:11,944,958...11,963,268
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of AXUD1 mRNA CTD PMID:19191707 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTNNB1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of CTNNB1 protein CTD PMID:12419474, PMID:24825450 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsl cathepsin L decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTSL mRNA CTD PMID:12419474 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cttn cortactin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CTTN mRNA CTD PMID:12419474 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cux1 cut-like homeobox 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CUX1 mRNA CTD PMID:12419474 NCBI chr12:23,150,886...23,470,095
Ensembl chr12:23,151,180...23,445,074
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein] CTD PMID:19627980 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CXCL14 mRNA CTD PMID:19191707 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CXCL1 mRNA CTD PMID:19191707 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of CXCR4 mRNA CTD PMID:19191707 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cybb cytochrome b-245 beta chain increases abundance ISO CYBB protein results in increased abundance of 4-hydroxy-2-nonenal CTD PMID:19417757 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal affects the localization of CYCS protein
pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal affects the localization of CYCS protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal affects the localization of CYCS protein]
CTD PMID:16322078, PMID:17263905, PMID:21187080 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP1A2 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYP1B1 mRNA CTD PMID:12419474 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [CYP2B6 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2B6 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2B6 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO [CYP2C29 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2C29 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2C29 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 multiple interactions ISO [CYP2J2 protein results in increased oxidation of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 4-hydroxy-2-nonenoic acid; [CYP2J2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene; CYP2J2 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal CTD PMID:21766881 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYSLTR1 mRNA CTD PMID:19191707 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cyth4 cytohesin 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of CYTH4 mRNA CTD PMID:19191707 NCBI chr 7:119,820,521...119,845,003
Ensembl chr 7:119,820,537...119,845,003
JBrowse link
G Dap death-associated protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of DAP mRNA CTD PMID:19191707 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DAPK1 mRNA CTD PMID:12419474 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DBF4 mRNA CTD PMID:19191707 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dcn decorin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DCN mRNA CTD PMID:19191707 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA; 4-hydroxy-2-nonenal results in increased expression of DDIT3 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA]
CTD PMID:24291486 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDIT4 mRNA CTD PMID:19191707 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDR2 mRNA CTD PMID:12419474 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx58 DEXD/H-box helicase 58 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DDX58 mRNA CTD PMID:19191707 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Denr density regulated reinitiation and release factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DENR mRNA CTD PMID:19191707 NCBI chr12:38,095,717...38,117,758
Ensembl chr12:38,096,034...38,116,919
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DFFA mRNA CTD PMID:12419474 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DFFB mRNA CTD PMID:12419474 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dgkh diacylglycerol kinase, eta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DGKH mRNA CTD PMID:19191707 NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769
JBrowse link
G Dhx58 DEXH-box helicase 58 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DHX58 mRNA CTD PMID:19191707 NCBI chr10:88,599,722...88,611,562
Ensembl chr10:88,599,680...88,611,105
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DIO2 mRNA CTD PMID:19191707 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of DLGAP5 mRNA
4-hydroxy-2-nonenal results in increased expression of DLGAP5 mRNA
CTD PMID:19191707 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of DNAJB4 mRNA CTD PMID:19191707 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DNAJC3 mRNA CTD PMID:12419474 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DNPH1 mRNA CTD PMID:12419474 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 affects binding ISO 4-hydroxy-2-nonenal binds to DPYSL2 protein CTD PMID:19374891 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP 4-hydroxy-2-nonenal results in decreased expression of DRD2 protein CTD PMID:20570720 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dst dystonin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of DST mRNA CTD PMID:12419474 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 affects binding ISO DYNLT3 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr  X:14,633,342...14,642,356
Ensembl chr  X:14,633,342...14,642,424
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of E2F1 mRNA CTD PMID:12419474 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of E2F2 mRNA CTD PMID:19191707 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of E2F8 mRNA CTD PMID:19191707 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ECHDC3 mRNA CTD PMID:19191707 NCBI chr17:76,002,304...76,022,813
Ensembl chr17:76,002,275...76,022,813
JBrowse link
G Edn1 endothelin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EDN1 mRNA CTD PMID:19191707 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression EXP 4-hydroxy-2-nonenal results in decreased expression of EEF2 protein CTD PMID:16469450 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Efna4 ephrin A4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EFNA4 mRNA CTD PMID:12419474 NCBI chr 2:188,655,920...188,660,179
Ensembl chr 2:188,655,912...188,660,179
JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EID3 mRNA CTD PMID:19191707 NCBI chr 7:26,976,154...26,977,479 JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2A protein CTD PMID:19041636 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EIF2AK2 mRNA CTD PMID:19191707 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2AK3 protein CTD PMID:19041636 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
EXP Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein] CTD PMID:24291486 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF4E mRNA CTD PMID:19191707 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF4E2 mRNA CTD PMID:19191707 NCBI chr 9:94,310,476...94,325,445
Ensembl chr 9:94,307,852...94,336,831
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation EXP 4-hydroxy-2-nonenal results in increased phosphorylation of EIF4EBP1 protein CTD PMID:9890986 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EIF5A mRNA CTD PMID:19191707 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Elk1 ETS transcription factor ELK1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELK1 mRNA CTD PMID:12419474 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Eloc elongin C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELOC mRNA CTD PMID:12419474 NCBI chr 5:2,042,991...2,059,357
Ensembl chr 5:2,042,991...2,059,351
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ELP1 mRNA CTD PMID:12419474 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EME1 mRNA CTD PMID:19191707 NCBI chr10:82,366,820...82,375,510
Ensembl chr10:82,367,084...82,374,171
JBrowse link
G Eno1 enolase 1 affects binding ISO 4-hydroxy-2-nonenal binds to ENO1 protein CTD PMID:19374891 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of EPHX1 mRNA CTD PMID:19191707 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPS15 mRNA CTD PMID:12419474 NCBI chr 5:128,923,809...129,022,268
Ensembl chr 5:128,923,934...129,022,054
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPS8 mRNA CTD PMID:12419474 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Epsti1 epithelial stromal interaction 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EPSTI1 mRNA CTD PMID:19191707 NCBI chr15:60,084,966...60,190,360
Ensembl chr15:60,084,918...60,190,363
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERBB2 mRNA CTD PMID:12419474 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERBB4 mRNA CTD PMID:12419474 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC1 mRNA CTD PMID:19191707 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC2 mRNA CTD PMID:12419474 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC5 mRNA CTD PMID:12419474 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERCC6L mRNA CTD PMID:19191707 NCBI chr  X:72,018,373...72,034,140
Ensembl chr  X:72,018,373...72,034,099
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ERN1 mRNA CTD PMID:19191707 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ESPL1 mRNA CTD PMID:19191707 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETS1 mRNA CTD PMID:12419474 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETS2 mRNA CTD PMID:12419474 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Etv3 ETS variant transcription factor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETV3 mRNA CTD PMID:12419474 NCBI chr 2:186,872,483...186,887,294
Ensembl chr 2:186,872,520...186,886,592
JBrowse link
G Etv6 ETS variant transcription factor 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ETV6 mRNA CTD PMID:12419474 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Ezr ezrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of EZR mRNA CTD PMID:12419474 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F10 coagulation factor X increases expression ISO 4-hydroxy-2-nonenal results in increased expression of F10 mRNA CTD PMID:19191707 NCBI chr16:81,803,169...81,822,476
Ensembl chr16:81,803,110...81,822,716
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of F2R mRNA CTD PMID:12419474 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of F3 mRNA CTD PMID:19191707 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fancd2 FA complementation group D2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FANCD2 mRNA CTD PMID:19191707 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FASTK mRNA CTD PMID:12419474 NCBI chr 4:7,260,521...7,264,590
Ensembl chr 4:7,260,575...7,264,589
JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXL17 mRNA CTD PMID:19191707 NCBI chr 9:110,515,558...110,936,631
Ensembl chr 9:110,515,558...110,936,631
JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of FBXL20 mRNA
4-hydroxy-2-nonenal results in increased expression of FBXL20 mRNA
CTD PMID:19191707 NCBI chr10:86,036,745...86,099,699
Ensembl chr10:86,043,235...86,098,694
JBrowse link
G Fbxo15 F-box protein 15 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO15 mRNA CTD PMID:19191707 NCBI chr18:81,785,408...81,882,796
Ensembl chr18:81,821,127...81,882,796
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO22 mRNA CTD PMID:19191707 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxo30 F-box protein 30 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO30 mRNA CTD PMID:19191707 NCBI chr 1:5,366,119...5,389,774
Ensembl chr 1:5,366,379...5,388,069
JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FBXO31 mRNA CTD PMID:19191707 NCBI chr19:53,487,610...53,625,673
Ensembl chr19:53,487,613...53,625,673
JBrowse link
G Fbxo39 F-box protein 39 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO39 mRNA CTD PMID:19191707 NCBI chr10:58,874,028...58,878,445
Ensembl chr10:58,875,826...58,878,445
JBrowse link
G Fbxo5 F-box protein 5 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of FBXO5 mRNA
4-hydroxy-2-nonenal results in increased expression of FBXO5 mRNA
CTD PMID:19191707 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FCGR1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of FCGR1A mRNA CTD PMID:19191707 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FCGR2B mRNA CTD PMID:19191707 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fcrl1 Fc receptor-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FCRL1 mRNA CTD PMID:19191707 NCBI chr 2:186,702,311...186,724,205
Ensembl chr 2:186,555,632...186,724,205
JBrowse link
G Fech ferrochelatase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FECH mRNA CTD PMID:12419474 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fem1c fem-1 homolog C decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FEM1C mRNA CTD PMID:19191707 NCBI chr18:40,493,156...40,518,988
Ensembl chr18:40,493,156...40,518,988
JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of FEN1 mRNA
4-hydroxy-2-nonenal results in decreased expression of FEN1 mRNA
CTD PMID:19191707 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FGFR1 mRNA CTD PMID:12419474 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression
decreases expression
ISO 4-hydroxy-2-nonenal results in increased expression of FGR mRNA
4-hydroxy-2-nonenal results in decreased expression of FGR mRNA
CTD PMID:19191707 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FKBP14 mRNA CTD PMID:19191707 NCBI chr 4:84,753,628...84,768,314
Ensembl chr 4:84,753,633...84,768,249
JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of FKBPL mRNA CTD PMID:19191707 NCBI chr20:4,411,890...4,413,360
Ensembl chr20:4,411,876...4,413,366
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO 4-hydroxy-2-nonenal results in decreased expression of FOS mRNA
resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of FOS protein]
CTD PMID:12419474, PMID:16322078 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]] CTD PMID:9890986 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FOXM1 mRNA CTD PMID:19191707 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO FOXO3 protein inhibits the reaction [SRT1720 inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal]] CTD PMID:24633890 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp1 forkhead box P1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FOXP1 mRNA CTD PMID:19191707 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Fpr3 formyl peptide receptor 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FPR3 mRNA CTD PMID:19191707 NCBI chr 1:116,152,526...116,161,873
Ensembl chr 1:116,152,667...116,153,722
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of FUBP1 mRNA CTD PMID:12419474 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of G6PDX mRNA CTD PMID:19191707 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GABARAPL1 mRNA CTD PMID:19191707 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA]
CTD PMID:19191707, PMID:24291486 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gak cyclin G associated kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GAK mRNA CTD PMID:12419474 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO [Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]] which results in decreased activity of GAPDH protein; [Hydroxyurea results in increased abundance of Free Radicals] promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]; Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein] CTD PMID:20889679, PMID:23696560 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata3 GATA binding protein 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GATA3 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GATAD2B mRNA CTD PMID:19191707 NCBI chr 2:189,654,871...189,735,056
Ensembl chr 2:189,655,702...189,733,540
JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GATB mRNA CTD PMID:19191707 NCBI chr 2:184,600,695...184,679,980
Ensembl chr 2:184,600,721...184,679,683
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP1 mRNA CTD PMID:19191707 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP3 mRNA CTD PMID:19191707 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gbp5 guanylate binding protein 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GBP5 mRNA CTD PMID:19191707 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GCLC mRNA
4-hydroxy-2-nonenal results in increased expression of GCLC protein
NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GCLC mRNA]
CTD PMID:19191707, PMID:24291486 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GCLM mRNA CTD PMID:19191707 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GEN1 mRNA CTD PMID:19191707 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Ggnbp1 gametogenetin binding protein 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GGNBP1 mRNA CTD PMID:19191707 NCBI chr20:5,618,973...5,625,320
Ensembl chr20:5,619,012...5,625,320
JBrowse link
G Gna13 G protein subunit alpha 13 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNA13 mRNA CTD PMID:19191707 NCBI chr10:97,647,196...97,680,030
Ensembl chr10:97,647,111...97,684,730
JBrowse link
G Gnaq G protein subunit alpha q increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GNAQ mRNA CTD PMID:19191707 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gnas GNAS complex locus decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNAS mRNA CTD PMID:12419474 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnat3 G protein subunit alpha transducin 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GNAT3 mRNA CTD PMID:19191707 NCBI chr 4:13,827,764...13,878,126
Ensembl chr 4:13,827,756...13,878,126
JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNB1 mRNA CTD PMID:12419474 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GNB2 mRNA CTD PMID:12419474 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GOT2 protein] CTD PMID:20889679 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpr183 G protein-coupled receptor 183 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GPR183 mRNA CTD PMID:19191707 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221
JBrowse link
G Gpx1 glutathione peroxidase 1 increases abundance ISO GPX1 gene mutant form results in increased abundance of 4-hydroxy-2-nonenal CTD PMID:24296279 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GPX2 mRNA CTD PMID:12419474 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
decreases phosphorylation
ISO 4-hydroxy-2-nonenal results in decreased expression of GSK3B mRNA
4-hydroxy-2-nonenal results in decreased phosphorylation of GSK3B protein
CTD PMID:12419474, PMID:24825450 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSN mRNA CTD PMID:19191707 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSR mRNA CTD PMID:19191707 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSS mRNA CTD PMID:19191707 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases response to substance
multiple interactions
affects metabolic processing
increases expression
ISO
EXP
GSTA1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
[GSTA1 protein binds to GSTA3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
GSTA1 protein affects the metabolism of 4-hydroxy-2-nonenal analog
4-hydroxy-2-nonenal results in increased expression of GSTA1 mRNA
CTD PMID:9799558, PMID:11256969, PMID:15829614 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased expression of GSTA3 mRNA
[GSTA1 protein binds to GSTA3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969, PMID:24423726 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
affects metabolic processing
increases expression
ISO
EXP
GSTA4 protein binds to and affects the metabolism of 4-hydroxy-2-nonenal
GSTA4 protein affects the metabolism of 4-hydroxy-2-nonenal; GSTA4 protein affects the metabolism of 4-hydroxy-2-nonenal analog
4-hydroxy-2-nonenal results in increased expression of GSTA4 mRNA; 4-hydroxy-2-nonenal results in increased expression of GSTA4 protein
CTD PMID:2619714, PMID:7878679, PMID:8142470, PMID:8203886, PMID:9461507, PMID:9799558, PMID:10514034, PMID:11162605, PMID:11256969, PMID:11302754, PMID:11488593, PMID:12600725, PMID:15829614, PMID:16005854 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of GSTA1 mRNA CTD PMID:19191707 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
affects metabolic processing
ISO
EXP
[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione; [GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal
[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
GSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969, PMID:21925487 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases response to substance
affects metabolic processing
multiple interactions
ISO
EXP
GSTM2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
GSTM2 protein affects the metabolism of 4-hydroxy-2-nonenal analog
[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog
CTD PMID:11256969, PMID:15829614 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression
affects binding
decreases response to substance
ISO
EXP
4-hydroxy-2-nonenal binds to and results in decreased activity of GSTP1 protein
4-hydroxy-2-nonenal results in increased expression of GSTP1 mRNA
Glutathione inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of GSTP1 protein]
4-hydroxy-2-nonenal analog binds to GSTP1
4-hydroxy-2-nonenal results in increased expression of GSTP1 protein
GSTP1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:9463521, PMID:11600134, PMID:15829614, PMID:18232660, PMID:19191707, PMID:20570720 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gtf2b general transcription factor IIB decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of GTF2B mRNA CTD PMID:12419474 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
ISO POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLK protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLL protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV3L protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein] CTD PMID:22331492 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) decreases activity ISO 4-hydroxy-2-nonenal results in decreased activity of H6PD protein CTD PMID:20211231 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Haspin histone H3 associated protein kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HASPIN mRNA CTD PMID:19191707 NCBI chr10:59,695,403...59,698,398
Ensembl chr10:59,695,913...59,698,168
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HBEGF mRNA CTD PMID:12419474 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HBP1 mRNA CTD PMID:19191707 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HCAR2 mRNA CTD PMID:19191707 NCBI chr12:38,160,464...38,161,546
Ensembl chr12:38,160,464...38,161,546
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HCK mRNA CTD PMID:19191707 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hdc histidine decarboxylase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HDC mRNA CTD PMID:19191707 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HELLS mRNA CTD PMID:19191707 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HERC3 mRNA CTD PMID:19191707 NCBI chr 4:89,078,670...89,169,150
Ensembl chr 4:89,078,711...89,169,146
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HERC5 mRNA CTD PMID:19191707 NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HGF mRNA CTD PMID:12419474 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HINT1 mRNA CTD PMID:12419474 NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
JBrowse link
G Hivep2 HIVEP zinc finger 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HIVEP2 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 1:8,129,354...8,333,890
Ensembl chr 1:8,310,577...8,333,885
JBrowse link
G Hivep3 HIVEP zinc finger 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HIVEP3 mRNA CTD PMID:19191707 NCBI chr 5:138,774,501...139,077,403
Ensembl chr 5:139,007,642...139,077,377
JBrowse link
G Hlx H2.0-like homeobox decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HLX mRNA CTD PMID:19191707 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223
JBrowse link
G Hmga1 high mobility group AT-hook 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HMGA1 mRNA CTD PMID:12419474 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HMGA2 mRNA CTD PMID:19191707 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal analog results in increased expression of HMOX1; 4-hydroxy-2-nonenal results in increased expression of HMOX1; 4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA; 4-hydroxy-2-nonenal results in increased expression of HMOX1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; methyl-beta-cyclodextrin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]
4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]
CTD PMID:18232660, PMID:19191707, PMID:20638469, PMID:23845594, PMID:24291486, PMID:24423726, PMID:30849339 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HNF4A mRNA CTD PMID:12419474 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HPRT1 mRNA CTD PMID:19191707 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSD17B11 mRNA CTD PMID:19191707 NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects binding EXP
ISO
4-hydroxy-2-nonenal binds to HSP90AA1 protein
4-hydroxy-2-nonenal analog binds to HSP90AA1
CTD PMID:18232660, PMID:21749116 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects binding EXP 4-hydroxy-2-nonenal binds to HSP90AB1 protein CTD PMID:21749116 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA1A CTD PMID:18232660 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPA1B mRNA CTD PMID:19191707 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA1L CTD PMID:18232660 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HSPA2 mRNA CTD PMID:12419474 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPA4L mRNA CTD PMID:19191707 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects binding
multiple interactions
increases expression
ISO
EXP
4-hydroxy-2-nonenal analog binds to HSPA5
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA]
4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA; 4-hydroxy-2-nonenal results in increased expression of HSPA5 protein
CTD PMID:18232660, PMID:24291486 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPA9 CTD PMID:18232660 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects binding ISO 4-hydroxy-2-nonenal analog binds to HSPD1 CTD PMID:18232660 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HSPH1 mRNA CTD PMID:19191707 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of HTATIP2 mRNA CTD PMID:19191707 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Htt huntingtin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HD mRNA CTD PMID:12419474 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of HUS1 mRNA CTD PMID:19191707 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of ICAM1 mRNA CTD PMID:19191707 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ID1 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IDH1 mRNA CTD PMID:19191707 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IER3 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFI44L mRNA CTD PMID:19191707 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIH1 mRNA CTD PMID:19191707 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIT2 mRNA CTD PMID:19191707 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFIT3 mRNA CTD PMID:19191707 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFITM2 mRNA CTD PMID:19191707 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:19627980 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Trichloroethylene co-treated with 4-hydroxy-2-nonenal analog] results in increased expression of IFNG protein CTD PMID:18267128 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IGF1 mRNA CTD PMID:19191707 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IGF1R mRNA CTD PMID:12419474 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IKBKE mRNA CTD PMID:19191707 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IKZF1 mRNA CTD PMID:19191707 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Il10 interleukin 10 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL10 mRNA CTD PMID:19191707 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of IL10RA mRNA CTD PMID:19191707 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL12RB1 mRNA CTD PMID:12419474 NCBI chr16:20,370,722...20,383,576
Ensembl chr16:20,371,338...20,383,337
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL13RA1 mRNA CTD PMID:19191707 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il17a interleukin 17A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL17A mRNA CTD PMID:12419474 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18rap interleukin 18 receptor accessory protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL18RAP mRNA CTD PMID:19191707 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1A mRNA CTD PMID:19191707 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1B mRNA CTD PMID:19191707 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1RL1 mRNA CTD PMID:19191707 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1RN mRNA CTD PMID:19191707 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Trichloroethylene co-treated with 4-hydroxy-2-nonenal analog] results in increased expression of IL2 protein CTD PMID:18267128 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il27 interleukin 27 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL27 mRNA CTD PMID:19191707 NCBI chr 1:198,003,615...198,010,112
Ensembl chr 1:198,003,683...198,008,893
JBrowse link
G Il3 interleukin 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL3 mRNA CTD PMID:12419474 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il36a interleukin 36, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL1F6 mRNA CTD PMID:19191707 NCBI chr 3:1,330,790...1,335,811
Ensembl chr 3:1,331,226...1,335,775
JBrowse link
G Il4r interleukin 4 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL4RA mRNA CTD PMID:19191707 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6 mRNA CTD PMID:19191707 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6R mRNA CTD PMID:12419474 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL6ST mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Il7r interleukin 7 receptor decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of IL7R mRNA
4-hydroxy-2-nonenal results in increased expression of IL7R mRNA
CTD PMID:12419474, PMID:19191707
G Il9 interleukin 9 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IL9 mRNA CTD PMID:12419474 NCBI chr17:8,558,827...8,561,950
Ensembl chr17:8,558,827...8,561,950
JBrowse link
G Impact impact RWD domain protein decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of IMPACT mRNA
4-hydroxy-2-nonenal results in increased expression of IMPACT mRNA
CTD PMID:19191707 NCBI chr18:4,325,872...4,346,734
Ensembl chr18:4,325,875...4,346,769
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of INPPL1 mRNA CTD PMID:19191707 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Insig2 insulin induced gene 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of INSIG2 mRNA CTD PMID:19191707 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRAK3 mRNA CTD PMID:19191707 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein] CTD PMID:19627980 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRF7 mRNA CTD PMID:19191707 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irf8 interferon regulatory factor 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRF8 mRNA CTD PMID:19191707 NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640
JBrowse link
G Irgm immunity-related GTPase M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IRGM mRNA CTD PMID:19191707 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ISG15 mRNA CTD PMID:19191707 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ISG20 mRNA CTD PMID:19191707 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA5 mRNA CTD PMID:12419474 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA6 mRNA CTD PMID:12419474 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itga7 integrin subunit alpha 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGA7 mRNA CTD PMID:12419474 NCBI chr 7:3,355,079...3,383,886
Ensembl chr 7:3,355,116...3,384,675
JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGAL mRNA CTD PMID:19191707 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGAM mRNA CTD PMID:19191707 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITGB6 mRNA CTD PMID:12419474 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Itsn1 intersectin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of ITSN1 mRNA CTD PMID:12419474 NCBI chr11:31,943,119...32,069,249
Ensembl chr11:31,893,489...32,069,249
JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of JAK2 mRNA CTD PMID:19191707 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of JDP2 mRNA CTD PMID:19191707 NCBI chr 6:109,464,910...109,505,591
Ensembl chr 6:109,466,060...109,505,161
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
increases phosphorylation
affects response to substance
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of JUN mRNA
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; 4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]]; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]
JUN protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]; 4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUN protein]]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of and results in increased phosphorylation of JUN protein]
CTD PMID:9890986, PMID:11488593, PMID:12419474, PMID:16322078, PMID:16337876, PMID:17263905 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]] CTD PMID:9890986 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of JUND mRNA
4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]; FOSL1 protein affects the reaction [4-hydroxy-2-nonenal results in increased activity of [JUN protein binds to JUND protein binds to JUNB protein]]
CTD PMID:9890986, PMID:12419474 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of KAT8 mRNA CTD PMID:19191707 NCBI chr 1:199,360,645...199,372,925
Ensembl chr 1:199,360,645...199,372,923
JBrowse link
G Kdm6b lysine demethylase 6B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KDM6B mRNA CTD PMID:19191707 NCBI chr10:56,000,494...56,009,582
Ensembl chr10:56,001,799...56,008,885
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KIF11 mRNA CTD PMID:19191707 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KIF20B mRNA CTD PMID:19191707 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kitlg KIT ligand increases expression ISO 4-hydroxy-2-nonenal results in increased expression of KITL mRNA CTD PMID:19191707 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf7 Kruppel like factor 7 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KLF7 mRNA CTD PMID:19191707 NCBI chr 9:70,740,480...70,787,913
Ensembl chr 9:70,740,480...70,787,913
JBrowse link
G Klhl6 kelch-like family member 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KLHL6 mRNA CTD PMID:19191707 NCBI chr11:84,745,958...84,785,315
Ensembl chr11:84,745,904...84,785,893
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of KPNA2 mRNA CTD PMID:19191707 NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
JBrowse link
G Lat linker for activation of T cells decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LAT mRNA CTD PMID:12419474 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LCAT mRNA CTD PMID:12419474 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LCK mRNA CTD PMID:12419474 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LIF mRNA CTD PMID:19191707 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LIPA mRNA CTD PMID:19191707 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LIPG mRNA CTD PMID:19191707 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of H2-Q1 mRNA CTD PMID:19191707 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100910669 paired immunoglobulin-like type 2 receptor alpha-like increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PILRA mRNA CTD PMID:19191707 NCBI chr12:21,678,550...21,689,821
Ensembl chr12:21,678,580...21,690,678
JBrowse link
G LOC103694381 lymphotoxin-beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LTB mRNA CTD PMID:19191707 NCBI chr20:4,861,343...4,863,513
Ensembl chr20:4,861,335...4,863,198
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LPAR1 mRNA CTD PMID:19191707 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
JBrowse link
G Lpin1 lipin 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LPIN1 mRNA CTD PMID:19191707 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrrc59 leucine rich repeat containing 59 affects binding ISO LRRC59 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr10:82,352,390...82,367,047
Ensembl chr10:82,352,390...82,367,047
JBrowse link
G Lrrfip2 LRR binding FLII interacting protein 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LRRFIP2 mRNA CTD PMID:19191707 NCBI chr 8:119,381,666...119,484,125
Ensembl chr 8:119,382,011...119,483,043
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LY6E mRNA CTD PMID:19191707 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of LY96 mRNA CTD PMID:19191707 NCBI chr 5:1,972,212...1,989,448 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of LYN mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAF1 mRNA CTD PMID:19191707 NCBI chr 7:117,417,643...117,420,722
Ensembl chr 7:117,417,687...117,420,719
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAFB mRNA CTD PMID:19191707 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAFG mRNA CTD PMID:19191707 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MAP1LC3B mRNA CTD PMID:19191707 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAP2K5 mRNA CTD PMID:12419474 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MAP3K20 mRNA CTD PMID:19191707 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases activity
multiple interactions
increases phosphorylation
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of MAPK1 protein
4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; 4-hydroxy-2-nonenal results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]; 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK1 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK1 protein
4-hydroxy-2-nonenal results in increased activity of and results in increased phosphorylation of MAPK1 protein
CTD PMID:16322078, PMID:17263905, PMID:23845594, PMID:24291486, PMID:24423726 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]
4-hydroxy-2-nonenal results in increased expression of MAPK14 mRNA
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]
CTD PMID:12684028, PMID:16322078, PMID:19191707 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases activity
multiple interactions
increases phosphorylation
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of MAPK3 protein
4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; 4-hydroxy-2-nonenal results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]; 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK3 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK3 protein
4-hydroxy-2-nonenal results in increased activity of and results in increased phosphorylation of MAPK3 protein
CTD PMID:16322078, PMID:17263905, PMID:23845594, PMID:24291486, PMID:24423726 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
increases phosphorylation
affects response to substance
multiple interactions
ISO 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein
4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein
MAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein; GSTA4 protein inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]
4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein; Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]
CTD PMID:11488593, PMID:12684028, PMID:15064094, PMID:16322078, PMID:17263905, PMID:24825450 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK9 protein CTD PMID:24825450 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Marcksl1 MARCKS-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MARCKSL1 mRNA CTD PMID:12419474 NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MARK3 mRNA CTD PMID:12419474 NCBI chr 6:136,040,957...136,129,780
Ensembl chr 6:136,041,777...136,129,661
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MCM4 mRNA CTD PMID:12419474 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MCM6 mRNA CTD PMID:19191707 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) increases expression ISO 4-hydroxy-2-nonenal results in increased expression of METAP1D mRNA CTD PMID:19191707 NCBI chr 3:58,084,558...58,160,748
Ensembl chr 3:58,084,606...58,162,675
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MITF mRNA CTD PMID:23489423 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MKI67 mRNA CTD PMID:19191707 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MKNK1 mRNA CTD PMID:19191707 NCBI chr 5:134,691,852...134,730,887
Ensembl chr 5:134,691,881...134,730,893
JBrowse link
G Mlh1 mutL homolog 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MLH1 mRNA CTD PMID:12419474 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases activity
increases expression
ISO 4-hydroxy-2-nonenal results in increased activity of MMP1 protein
4-hydroxy-2-nonenal results in increased expression of MMP1 mRNA
CTD PMID:14672615 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity
increases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in increased activity of MMP2 protein
4-hydroxy-2-nonenal results in increased expression of MMP2 mRNA
1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2]; 4-hydroxy-2-nonenal results in increased expression of and results in increased secretion of and results in increased activity of MMP2 protein; AKT1 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2 protein]
CTD PMID:14672615, PMID:18805481 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
increases activity
multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of MMP9 mRNA
4-hydroxy-2-nonenal results in increased activity of MMP9 protein
ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; MK-886 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; U 75302 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]
4-hydroxy-2-nonenal results in increased expression of MMP9 mRNA; 4-hydroxy-2-nonenal results in increased expression of MMP9 protein
CTD PMID:19191707, PMID:19837106 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of IFI16 mRNA; 4-hydroxy-2-nonenal results in decreased expression of IFI204 mRNA
4-hydroxy-2-nonenal results in decreased expression of MNDA mRNA
CTD PMID:12419474, PMID:19191707 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Mocos molybdenum cofactor sulfurase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MOCOS mRNA CTD PMID:19191707 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MOV10 mRNA CTD PMID:19191707 NCBI chr 2:207,277,088...207,301,245
Ensembl chr 2:207,278,161...207,300,854
JBrowse link
G Ms4a6e membrane spanning 4-domains A6E decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MS4A6C mRNA CTD PMID:19191707 NCBI chr 1:227,757,444...227,769,336
Ensembl chr 1:227,757,425...227,818,305
Ensembl chr 1:227,757,425...227,818,305
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MSH5 mRNA CTD PMID:19191707 NCBI chr20:5,020,690...5,037,125
Ensembl chr20:5,020,667...5,037,088
JBrowse link
G Mt1 metallothionein 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MT1 mRNA CTD PMID:20979157 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MT2 mRNA CTD PMID:19191707 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MTHFS mRNA CTD PMID:19191707 NCBI chr 8:96,564,877...96,614,386
Ensembl chr 8:96,564,877...96,614,348
JBrowse link
G Mtmr10 myotubularin related protein 10 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MTMR10 mRNA CTD PMID:19191707 NCBI chr 1:125,124,743...125,175,857
Ensembl chr 1:125,124,743...125,175,857
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MTOR mRNA CTD PMID:12419474 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MTSS1 mRNA CTD PMID:19191707 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Mutyh mutY DNA glycosylase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of MUTYH mRNA CTD PMID:19191707 NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MX1 mRNA; 4-hydroxy-2-nonenal results in decreased expression of MX2 mRNA CTD PMID:19191707 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Mxd1 max dimerization protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MXD1 mRNA CTD PMID:19191707 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYBL2 mRNA CTD PMID:12419474 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYC mRNA CTD PMID:12419474 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of MYLK mRNA CTD PMID:12419474 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Nab2 Ngfi-A binding protein 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NAB2 mRNA CTD PMID:19191707 NCBI chr 7:70,963,580...70,971,471
Ensembl chr 7:70,961,575...70,969,905
JBrowse link
G Napb NSF attachment protein beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NAPB mRNA CTD PMID:19191707 NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
JBrowse link
G Nbn nibrin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NBN mRNA CTD PMID:12419474, PMID:19191707 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Nck1 NCK adaptor protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NCK1 mRNA CTD PMID:12419474 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NDC80 mRNA CTD PMID:19191707 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NECTIN1 mRNA CTD PMID:12419474 NCBI chr 8:48,094,233...48,198,499
Ensembl chr 8:48,094,673...48,157,305
JBrowse link
G Neil3 nei-like DNA glycosylase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEIL3 mRNA CTD PMID:19191707 NCBI chr16:41,079,444...41,138,505
Ensembl chr16:41,079,444...41,138,505
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of NEK2 mRNA
4-hydroxy-2-nonenal results in increased expression of NEK2 mRNA
CTD PMID:19191707 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Nek3 NIMA-related kinase 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NEK3 mRNA CTD PMID:19191707 NCBI chr16:74,781,371...74,806,567
Ensembl chr16:74,785,281...74,806,149
JBrowse link
G Nek6 NIMA-related kinase 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEK6 mRNA CTD PMID:19191707 NCBI chr 3:22,811,927...22,888,598
Ensembl chr 3:22,811,927...22,888,598
JBrowse link
G Neo1 neogenin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NEO1 mRNA CTD PMID:12419474 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Nf2 neurofibromin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NF2 mRNA CTD PMID:12419474 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFAM1 mRNA CTD PMID:19191707 NCBI chr 7:123,856,718...123,893,790
Ensembl chr 7:123,856,567...123,892,429
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFATC1 mRNA CTD PMID:12419474 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFE2L1 mRNA CTD PMID:12419474 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases activity
multiple interactions
affects response to substance
affects localization
increases expression
ISO
EXP
4-hydroxy-2-nonenal results in decreased activity of NFE2L2 protein
AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal]
4-hydroxy-2-nonenal affects the localization of NFE2L2 protein
4-hydroxy-2-nonenal affects the localization of and results in increased activity of NFE2L2 protein; [GSTA4 protein mutant form results in decreased glutathionylation of 4-hydroxy-2-nonenal] which results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; NFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased activity of NFE2L2 protein]
4-hydroxy-2-nonenal results in increased expression of NFE2L2 protein
NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]
CTD PMID:16322078, PMID:19880816, PMID:24291486, PMID:24423726, PMID:24633890, PMID:29108775, PMID:30849339 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfic nuclear factor I/C increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFIC mRNA CTD PMID:19191707 NCBI chr 7:11,151,941...11,179,544
Ensembl chr 7:11,152,038...11,177,664
JBrowse link
G Nfix nuclear factor I X decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFIX mRNA CTD PMID:12419474 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression
multiple interactions
ISO
EXP
4-hydroxy-2-nonenal results in decreased expression of NFKB1 mRNA
4-hydroxy-2-nonenal results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; 4-hydroxy-2-nonenal results in decreased activity of [RELA protein binds to NFKB1 protein]
CTD PMID:11146106, PMID:12419474, PMID:19191707 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
4-hydroxy-2-nonenal results in increased expression of NFKBIA mRNA
CTD PMID:19191707, PMID:19627980 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NFKBIE mRNA CTD PMID:19191707 NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
JBrowse link
G Nfkbiz NFKB inhibitor zeta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFKBIZ mRNA CTD PMID:19191707 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFRKB mRNA CTD PMID:12419474 NCBI chr 8:32,530,412...32,561,955
Ensembl chr 8:32,530,412...32,561,955
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NFX1 mRNA CTD PMID:12419474 NCBI chr 5:57,290,916...57,348,720
Ensembl chr 5:57,291,156...57,348,720
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NKIRAS1 mRNA CTD PMID:19191707 NCBI chr15:8,179,090...8,188,656
Ensembl chr15:8,179,102...8,183,682
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRC4 mRNA CTD PMID:19191707 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250
JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRP10 mRNA CTD PMID:19191707 NCBI chr 1:173,521,412...173,528,969
Ensembl chr 1:173,520,413...173,528,943
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NLRP3 mRNA CTD PMID:19191707 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nmb neuromedin B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NMB mRNA CTD PMID:12419474 NCBI chr 1:142,721,263...142,724,646
Ensembl chr 1:142,721,002...142,724,511
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NME2 mRNA CTD PMID:12419474 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NOS2 protein CTD PMID:20940037 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NOTCH1 mRNA CTD PMID:19191707 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NQO1 mRNA
4-hydroxy-2-nonenal results in increased expression of NQO1 mRNA; 4-hydroxy-2-nonenal results in increased expression of NQO1 protein
CTD PMID:24423726, PMID:29108775, PMID:30849339 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR1D1 mRNA CTD PMID:19191707 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NR1D2 mRNA CTD PMID:19191707 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR1I3 mRNA CTD PMID:12419474 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR2F6 mRNA CTD PMID:12419474 NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR3C1 mRNA CTD PMID:19191707 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NR4A1 mRNA CTD PMID:19191707 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nrp1 neuropilin 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NRP1 mRNA CTD PMID:19191707 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NSL1 mRNA CTD PMID:19191707 NCBI chr13:109,669,646...109,697,849
Ensembl chr13:109,669,680...109,696,918
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUF2 mRNA CTD PMID:19191707 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Nufip1 nuclear FMR1 interacting protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUFIP1 mRNA CTD PMID:19191707 NCBI chr15:58,171,163...58,201,888
Ensembl chr15:58,170,967...58,201,970
JBrowse link
G Nup210 nucleoporin 210 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NUP210 mRNA CTD PMID:19191707 NCBI chr 4:122,643,952...122,741,322
Ensembl chr 4:122,644,135...122,741,110
JBrowse link
G Nup85 nucleoporin 85 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of NUP85 mRNA CTD PMID:19191707 NCBI chr10:104,118,999...104,137,258
Ensembl chr10:104,118,945...104,137,319
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of NUSAP1 mRNA CTD PMID:19191707 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of OAS3 mRNA CTD PMID:19191707 NCBI chr12:41,313,081...41,368,217
Ensembl chr12:41,316,764...41,336,562
JBrowse link
G Olr1271 olfactory receptor 1271 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of OLFR933 mRNA CTD PMID:19191707 NCBI chr 8:42,776,302...42,780,782
Ensembl chr 8:42,779,545...42,780,474
JBrowse link
G Osm oncostatin M decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of OSM mRNA CTD PMID:19191707 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G P2rx5 purinergic receptor P2X 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of P2RX5 mRNA CTD PMID:12419474 NCBI chr10:59,725,438...59,737,126
Ensembl chr10:59,725,398...59,737,126
JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of P2RY2 mRNA CTD PMID:19191707 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta affects metabolic processing EXP 4-hydroxy-2-nonenal affects the metabolism of P4HB protein CTD PMID:16097806 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PA2G4 mRNA CTD PMID:19191707 NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PAIP1 mRNA CTD PMID:12419474 NCBI chr 2:52,300,921...52,328,212
Ensembl chr 2:52,301,798...52,328,205
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases degradation ISO 4-hydroxy-2-nonenal results in increased degradation of PARP1 protein CTD PMID:11488593 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Parp12 poly (ADP-ribose) polymerase family, member 12 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PARP12 mRNA CTD PMID:19191707 NCBI chr 4:66,835,647...66,900,324
Ensembl chr 4:66,849,554...66,899,914
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PBK mRNA CTD PMID:19191707 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pcgf5 polycomb group ring finger 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PCGF5 mRNA CTD PMID:19191707 NCBI chr 1:254,974,688...255,090,925
Ensembl chr 1:254,974,789...255,086,207
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PCNA mRNA CTD PMID:19191707 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PCSK2 mRNA CTD PMID:12419474 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pcyox1 prenylcysteine oxidase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PCYOX1 mRNA CTD PMID:19191707 NCBI chr 4:118,187,133...118,198,029
Ensembl chr 4:118,187,134...118,198,029
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PDCD4 mRNA CTD PMID:19191707 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PDGFB mRNA CTD PMID:19191707 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects binding ISO 4-hydroxy-2-nonenal analog binds to PDIA3 CTD PMID:18232660 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PDSS1 mRNA CTD PMID:19191707 NCBI chr17:90,033,432...90,072,506
Ensembl chr17:90,033,539...90,071,408
JBrowse link
G Pdyn prodynorphin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PDYN mRNA CTD PMID:12419474 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Penk proenkephalin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PENK mRNA CTD PMID:19191707 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Per1 period circadian regulator 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PER1 mRNA CTD PMID:19191707 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pex7 peroxisomal biogenesis factor 7 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PEX7 mRNA CTD PMID:19191707 NCBI chr 1:15,311,768...15,374,702
Ensembl chr 1:15,311,770...15,374,850
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGD mRNA CTD PMID:19191707 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGLYRP3 mRNA CTD PMID:19191707 NCBI chr 2:191,903,626...192,264,872
Ensembl chr 2:192,253,629...192,264,840
JBrowse link
G Pgm2l1 phosphoglucomutase 2-like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PGM2L1 mRNA CTD PMID:19191707 NCBI chr 1:165,237,847...165,286,980
Ensembl chr 1:165,237,847...165,286,980
JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PGS1 mRNA CTD PMID:19191707 NCBI chr10:106,994,595...107,030,208
Ensembl chr10:106,991,935...107,030,260
JBrowse link
G Phb prohibitin decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHB mRNA CTD PMID:12419474 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phf11 PHD finger protein 11 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHF11 mRNA CTD PMID:19191707 NCBI chr15:38,692,817...39,683,417
Ensembl chr15:38,647,779...38,709,984
JBrowse link
G Phf21a PHD finger protein 21A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PHF21A mRNA CTD PMID:19191707 NCBI chr 3:81,099,765...81,271,841
Ensembl chr 3:81,134,505...81,271,849
JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects binding ISO PHGDH protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PHLDA1 mRNA CTD PMID:19191707 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PIK3CB mRNA CTD PMID:19191707 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PIK3CD mRNA CTD PMID:19191707 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PIK3R2 mRNA CTD PMID:12419474 NCBI chr16:20,415,109...20,424,982
Ensembl chr16:20,416,432...20,424,980
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PILRA mRNA CTD PMID:19191707 NCBI chr12:21,412,598...21,418,621
Ensembl chr12:21,412,538...21,420,169
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 affects binding
increases response to substance
ISO 4-hydroxy-2-nonenal binds to PIN1 protein
PIN1 protein results in increased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:23231502 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Pkm pyruvate kinase M1/2 affects binding
multiple interactions
ISO 4-hydroxy-2-nonenal analog binds to PKM protein
4-hydroxy-2-nonenal binds to and results in decreased activity of PKM protein; 4-hydroxy-2-nonenal promotes the reaction [PKM protein binds to PKM protein]
CTD PMID:27978618 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLA2G7 mRNA CTD PMID:19191707 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PLAGL2 mRNA CTD PMID:19191707 NCBI chr 3:148,709,564...148,722,777
Ensembl chr 3:148,709,531...148,722,742
JBrowse link
G Pld2 phospholipase D2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLD2 mRNA CTD PMID:19191707 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLEKHM1 mRNA CTD PMID:19191707 NCBI chr10:91,451,890...91,500,675
Ensembl chr10:91,451,865...91,500,661
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of PLEKHO1 mRNA
4-hydroxy-2-nonenal results in increased expression of PLEKHO1 mRNA
CTD PMID:19191707 NCBI chr 2:198,112,104...198,120,202
Ensembl chr 2:198,112,076...198,120,120
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PLK1 mRNA CTD PMID:19191707 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PLK2 mRNA CTD PMID:19191707 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Polb DNA polymerase beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLB mRNA CTD PMID:12419474 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLD1 mRNA CTD PMID:12419474 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit increases expression ISO 4-hydroxy-2-nonenal results in increased expression of POLE mRNA CTD PMID:19191707 NCBI chr12:52,403,533...52,452,075
Ensembl chr12:52,403,529...52,452,040
JBrowse link
G Polh DNA polymerase eta multiple interactions
affects response to substance
ISO POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
POLH protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polk DNA polymerase kappa multiple interactions ISO POLK protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein] CTD PMID:22331492 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link
G Poll DNA polymerase lambda affects response to substance
multiple interactions
ISO POLL protein affects the susceptibility to 4-hydroxy-2-nonenal
POLL protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
CTD PMID:22331492 NCBI chr 1:265,290,337...265,298,847
Ensembl chr 1:265,290,339...265,298,797
JBrowse link
G Polq DNA polymerase theta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POLQ mRNA CTD PMID:19191707 NCBI chr11:66,585,860...66,695,369
Ensembl chr11:66,585,881...66,695,353
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
ISO 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
4-hydroxy-2-nonenal results in decreased activity of PON1 protein
CTD PMID:15375178 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pou2f2 POU class 2 homeobox 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of POU2F2 mRNA CTD PMID:19191707 NCBI chr 1:81,966,791...82,049,116
Ensembl chr 1:81,964,104...82,004,538
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPARG protein CTD PMID:27417252 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppid peptidylprolyl isomerase D increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PPID mRNA CTD PMID:19191707 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PPIL1 mRNA CTD PMID:19191707 NCBI chr20:6,515,638...6,864,571
Ensembl chr20:6,515,638...6,864,571
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP1CA mRNA CTD PMID:12419474 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
multiple interactions
EXP 4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA]
CTD PMID:24291486 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP1R15B mRNA CTD PMID:19191707 NCBI chr13:49,933,155...49,940,961
Ensembl chr13:49,933,155...49,940,961
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PPP3CA mRNA CTD PMID:12419474 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PRDM1 mRNA CTD PMID:12419474 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prdx1 peroxiredoxin 1 affects binding
increases expression
ISO 4-hydroxy-2-nonenal analog binds to PRDX1
4-hydroxy-2-nonenal results in increased expression of PRDX1 mRNA
CTD PMID:18232660, PMID:19191707 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PRKDC mRNA CTD PMID:12419474 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Procr protein C receptor increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PROCR mRNA CTD PMID:19191707 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PSMB10 mRNA CTD PMID:19191707 NCBI chr19:37,909,543...37,912,027
Ensembl chr19:37,909,546...37,912,027
JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PSMC3IP mRNA CTD PMID:19191707 NCBI chr10:89,002,109...89,006,075
Ensembl chr10:89,002,116...89,005,213
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PSMD12 mRNA CTD PMID:19191707 NCBI chr10:95,706,808...95,725,452
Ensembl chr10:95,706,685...95,725,812
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTGER4 mRNA CTD PMID:19191707 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptges prostaglandin E synthase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PTGES mRNA CTD PMID:19191707 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions
decreases response to substance
EXP [PTGR1 protein co-treated with NADP] affects the reduction of 4-hydroxy-2-nonenal
PTGR1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal
CTD PMID:11524419 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTK2 mRNA CTD PMID:12419474 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PTPN1 mRNA CTD PMID:12419474 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A increases expression ISO 4-hydroxy-2-nonenal results in increased expression of PTPRA mRNA CTD PMID:19191707 NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
JBrowse link
G Pxk PX domain containing serine/threonine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of PXK mRNA CTD PMID:19191707 NCBI chr15:18,548,209...18,616,617
Ensembl chr15:18,548,212...18,616,589
JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAB11A mRNA CTD PMID:19191707 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RABGEF1 mRNA CTD PMID:19191707 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAD23A mRNA CTD PMID:19191707 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression
ISO 4-hydroxy-2-nonenal results in decreased expression of RAD51 mRNA
4-hydroxy-2-nonenal results in increased expression of RAD51 mRNA
CTD PMID:19191707 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad54l RAD54 like decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RAD54L mRNA CTD PMID:19191707 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Raet1e retinoic acid early transcript 1E increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAET1E mRNA CTD PMID:19191707 NCBI chr 1:1,101,666...1,120,340
Ensembl chr 1:1,101,965...1,116,926
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RAF1 mRNA CTD PMID:19191707 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ralbp1 ralA binding protein 1 decreases response to substance ISO RALBP1 protein results in decreased susceptibility to 4-hydroxy-2-nonenal CTD PMID:15950949 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RALGDS mRNA CTD PMID:12419474 NCBI chr 3:7,090,134...7,130,548
Ensembl chr 3:7,109,920...7,130,548
JBrowse link
G Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RALGPS1 mRNA CTD PMID:19191707 NCBI chr 3:12,182,722...12,415,081
Ensembl chr 3:12,178,853...12,415,073
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RARA mRNA CTD PMID:19191707 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RARB mRNA CTD PMID:12419474 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rasgef1b RasGEF domain family, member 1B increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RASGEF1B mRNA CTD PMID:19191707 NCBI chr14:11,499,692...12,028,513
Ensembl chr14:11,988,671...12,027,381
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RASGRP3 mRNA CTD PMID:19191707 NCBI chr 6:21,072,634...21,171,619
Ensembl chr 6:21,072,634...21,135,880
JBrowse link
G Rassf2 Ras association domain family member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RASSF2 mRNA CTD PMID:19191707 NCBI chr 3:124,574,088...124,610,267
Ensembl chr 3:124,575,621...124,610,267
JBrowse link
G Rassf8 Ras association domain family member 8 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RASSF8 mRNA CTD PMID:19191707 NCBI chr 4:180,059,020...180,135,924
Ensembl chr 4:180,062,799...180,135,966
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO 4-hydroxy-2-nonenal results in decreased phosphorylation of RB1 protein CTD PMID:15607904 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RBL1 mRNA CTD PMID:19191707 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RBL2 mRNA CTD PMID:12419474 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of REL mRNA CTD PMID:12419474 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 4-hydroxy-2-nonenal results in decreased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11146106 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rev1 REV1, DNA directed polymerase multiple interactions
affects response to substance
ISO REV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
REV1 protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr 9:44,714,137...44,786,330
Ensembl chr 9:44,714,386...44,786,041
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit multiple interactions
affects response to substance
ISO REV3L protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]
REV3L protein affects the susceptibility to 4-hydroxy-2-nonenal
CTD PMID:22331492 NCBI chr20:44,803,664...44,961,362
Ensembl chr20:44,803,666...44,961,382
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RFFL mRNA CTD PMID:19191707 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rgs1 regulator of G-protein signaling 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RGS1 mRNA CTD PMID:19191707 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599
JBrowse link
G Riok3 RIO kinase 3 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RIOK3 mRNA CTD PMID:19191707 NCBI chr18:3,565,166...3,590,739
Ensembl chr18:3,565,166...3,590,739
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RIT1 mRNA CTD PMID:19191707 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RND1 mRNA CTD PMID:19191707 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Rnf128 ring finger protein 128 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RNF128 mRNA CTD PMID:19191707 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978
JBrowse link
G Rnf167 ring finger protein 167 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RNF167 mRNA CTD PMID:19191707 NCBI chr10:57,268,331...57,272,667
Ensembl chr10:57,268,375...57,272,660
JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RNF19B mRNA CTD PMID:19191707 NCBI chr 5:147,246,032...147,270,892
Ensembl chr 5:147,246,037...147,270,957
JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RPP38 mRNA CTD PMID:19191707 NCBI chr17:78,915,450...78,919,144
Ensembl chr17:78,915,604...78,919,143
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RPS6KA2 mRNA CTD PMID:12419474 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation EXP 4-hydroxy-2-nonenal results in increased phosphorylation of RPS6KB1 protein CTD PMID:19289642 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RSAD2 mRNA CTD PMID:19191707 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G RT1-DMb RT1 class II, locus DMb decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of H2-DMB2 mRNA CTD PMID:19191707 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of H2-T23 mRNA CTD PMID:19191707 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO 4-hydroxy-2-nonenal results in increased expression of RXRA mRNA CTD PMID:19191707 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of RXRB mRNA CTD PMID:12419474 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of S1PR2 mRNA CTD PMID:19191707 NCBI chr 8:21,984,914...21,995,806
Ensembl chr 8:21,984,914...21,995,806
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 affects binding ISO SAMHD1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 3:153,210,829...153,250,705
Ensembl chr 3:153,210,829...153,250,641
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SAMSN1 mRNA CTD PMID:19191707 NCBI chr11:14,252,088...14,405,825
Ensembl chr11:14,253,848...14,304,725
JBrowse link
G Sass6 SAS-6 centriolar assembly protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SASS6 mRNA CTD PMID:19191707 NCBI chr 2:219,626,851...219,660,975
Ensembl chr 2:219,628,695...219,652,968
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SATB1 mRNA CTD PMID:12419474 NCBI chr 9:2,181,135...2,277,949
Ensembl chr 9:2,190,915...2,274,629
JBrowse link
G Sbno2 strawberry notch homolog 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SBNO2 mRNA CTD PMID:19191707 NCBI chr 7:12,471,805...12,515,700
Ensembl chr 7:12,471,824...12,518,654
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
affects binding
ISO Tobacco Smoke Pollution promotes the reaction [4-hydroxy-2-nonenal binds to SCARB1 protein] CTD PMID:22442701 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SELENBP1 mRNA CTD PMID:12419474 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 affects binding ISO SERBP1 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr 4:98,027,563...98,044,717
Ensembl chr 4:98,027,554...98,044,566
JBrowse link
G Serpinb5 serpin family B member 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SERPINB5 mRNA CTD PMID:12419474 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SERPINB9 mRNA CTD PMID:19191707 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SERPINI1 mRNA CTD PMID:12419474 NCBI chr 2:174,013,058...174,111,693
Ensembl chr 2:174,013,288...174,111,752
JBrowse link
G Sesn2 sestrin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SESN2 mRNA CTD PMID:19191707 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGK1 mRNA CTD PMID:19191707 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGO1 mRNA CTD PMID:19191707 NCBI chr 9:4,420,158...4,435,939
Ensembl chr 9:4,421,069...4,436,601
JBrowse link
G Sgo2 shugoshin 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SGO2 mRNA CTD PMID:19191707 NCBI chr 9:64,898,380...64,923,023
Ensembl chr 9:64,898,459...64,923,012
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SGPL1 mRNA CTD PMID:19191707 NCBI chr20:30,699,936...30,769,178
Ensembl chr20:30,699,872...30,749,940
JBrowse link
G Shoc2 SHOC2 leucine-rich repeat scaffold protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SHOC2 mRNA CTD PMID:12419474 NCBI chr 1:274,700,621...274,751,195
Ensembl chr 1:274,688,580...274,751,816
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO SIRT1 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of 4-hydroxy-2-nonenal] CTD PMID:24633890 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO 4-hydroxy-2-nonenal binds to and results in decreased activity of SIRT3 protein CTD PMID:21449565 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Slc25a27 solute carrier family 25, member 27 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SLC25A27 mRNA CTD PMID:20385226 NCBI chr 9:19,880,468...19,907,506
Ensembl chr 9:19,880,473...19,907,458
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [APC protein mutant form results in increased expression of SLC7A11 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal CTD PMID:21967605 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SLC7A2 mRNA CTD PMID:19191707 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349
JBrowse link
G Smad1 SMAD family member 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SMAD1 mRNA CTD PMID:12419474 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SMC4 mRNA CTD PMID:19191707 NCBI chr 2:165,600,934...165,629,415
Ensembl chr 2:165,601,007...165,629,415
JBrowse link
G Snapc5 small nuclear RNA activating complex, polypeptide 5 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SNAPC5 mRNA CTD PMID:19191707 NCBI chr 8:69,127,708...69,131,539
Ensembl chr 8:69,127,708...69,131,539
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SOCS3 mRNA CTD PMID:19191707 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod2 superoxide dismutase 2 affects binding
increases abundance
multiple interactions
decreases abundance
increases expression
ISO 4-hydroxy-2-nonenal binds to SOD2 protein
SOD2 gene mutant form results in increased abundance of 4-hydroxy-2-nonenal
SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]
SOD2 protein results in decreased abundance of 4-hydroxy-2-nonenal
4-hydroxy-2-nonenal results in increased expression of SOD2 mRNA
CTD PMID:11507057, PMID:19191707, PMID:19374891, PMID:23199288 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp100 SP100 nuclear antigen decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP100 mRNA CTD PMID:19191707 NCBI chr 9:92,675,103...92,718,489
Ensembl chr 9:92,681,078...92,717,929
JBrowse link
G Sp110 SP110 nuclear body protein decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP110 mRNA CTD PMID:19191707 NCBI chr 9:92,593,909...92,618,867
Ensembl chr 9:92,593,910...92,616,165
JBrowse link
G Sp2 Sp2 transcription factor decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SP2 mRNA CTD PMID:12419474 NCBI chr10:84,890,930...84,920,886
Ensembl chr10:84,890,932...84,920,886
JBrowse link
G Spa17 sperm autoantigenic protein 17 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SPA17 mRNA CTD PMID:19191707 NCBI chr 8:40,066,954...40,078,131
Ensembl chr 8:40,067,076...40,078,165
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPAG5 mRNA CTD PMID:19191707 NCBI chr10:65,552,780...65,585,773
Ensembl chr10:65,566,171...65,585,760
Ensembl chr10:65,566,171...65,585,760
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPRY1 mRNA CTD PMID:19191707 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SPRY2 mRNA CTD PMID:12419474 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA CTD PMID:19191707 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases expression ISO 4-hydroxy-2-nonenal results in decreased expression of SRC mRNA CTD PMID:19191707 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srp9 signal recognition particle 9 affects binding ISO SRP9 protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 NCBI chr13:100,551,307...100,559,447
Ensembl chr13:100,551,307...100,559,447
JBrowse link
G Srpk2 SRSF protein kinase 2 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SRPK2 mRNA CTD PMID:19191707 NCBI chr 4:7,994,025...8,187,455
Ensembl chr 4:8,066,737...8,185,935
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 4-hydroxy-2-nonenal results in increased expression of SRXN1 mRNA CTD PMID:19191707, PMID:22003191 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G