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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:all-cis-docosa-7,10,13,16-tetraenoic acid
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Accession:CHEBI:53487 term browser browse the term
Definition:The all-cis-isomer of a C22 polyunsaturated fatty acid having four double bonds in the 7-, 10-, 13- and 16-positions. One of the most abundant fatty acids in the early human brain.
Synonyms:related_synonym: (7Z,10Z,13Z,16Z)-Docosa-7,10,13,16-tetraenoic acid;   7,10,13,16-Docosatetraenoic acid;   7Z,10Z,13Z,16Z-docosatetraenoic acid;   Formula=C22H36O2;   InChI=1S/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-;   InChIKey=TWSWSIQAPQLDBP-DOFZRALJSA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCCCC(O)=O;   adrenic acid;   all-cis-7,10,13,16-docosatetraenoic acid;   cis,cis,cis,cis-Docosa-7,10,13,16-tetraensaeure
 xref: Beilstein:1914611;   CAS:28874-58-0;   HMDB:HMDB0002226;   KEGG:C16527;   LIPID_MAPS_instance:LMFA01030178
 xref_mesh: MESH:C011395
 xref: PMID:11971947;   PMID:1532827;   PMID:17291553;   PMID:2538146;   PMID:3021726;   Reaxys:1914611;   Wikipedia:Adrenic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:77225


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all-cis-docosa-7,10,13,16-tetraenoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha multiple interactions ISO adrenic acid binds to and results in increased activity of RXRA protein CTD PMID:16258897 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of adrenic acid CTD PMID:30258081 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        biochemical role 19529
          metabolite 19515
            eukaryotic metabolite 19337
              algal metabolite 15575
                all-cis-docosa-7,10,13,16-tetraenoic acid 2
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl group 0
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA 0
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
                  1,2-di-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 0
                  1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-2-octadecanoyl-sn-glycero-3-phosphocholine 0
                  1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-[(9Z)-octadecenoyl]-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-hexadecanoyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-icosyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine 0
                  1-octadecyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-oleoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoethanolamine 0
                  1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoserine 0
                  1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  CE(22:4(7Z,10Z,13Z,16Z)) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18008
                                        fatty acid 16809
                                          unsaturated fatty acid 1094
                                            polyunsaturated fatty acid 838
                                              essential fatty acid 563
                                                omega-6 fatty acid 556
                                                  all-cis-docosa-7,10,13,16-tetraenoic acid 2
                                                    (7Z,10Z,13Z,16Z)-docosatetraenoyl group 0
                                                    (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA 0
                                                    (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
                                                    1,2-di-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                    1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 0
                                                    1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-2-octadecanoyl-sn-glycero-3-phosphocholine 0
                                                    1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                    1-[(9Z)-octadecenoyl]-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                    1-hexadecanoyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                    1-icosyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                    1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine 0
                                                    1-octadecyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                    1-oleoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                    1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                    1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                    1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoserine 0
                                                    1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                    CE(22:4(7Z,10Z,13Z,16Z)) 0
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