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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:S-(hydroxymethyl)glutathione
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Accession:CHEBI:48926 term browser browse the term
Definition:An S-substituted glutathione that is glutathione in which the mercapto hydrogen has been replaced by a hydroxymethyl group.
Synonyms:related_synonym: Formula=C11H19N3O7S;   InChI=1S/C11H19N3O7S/c12-6(11(20)21)1-2-8(16)14-7(4-22-5-15)10(19)13-3-9(17)18/h6-7,15H,1-5,12H2,(H,13,19)(H,14,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1;   InChIKey=PIUSLWSYOYFRFR-BQBZGAKWSA-N;   L-gamma-glutamyl-S-(hydroxymethyl)-L-cysteinylglycine;   S-hydroxymethylglutathione;   SMILES=N[C@@H](CCC(=O)N[C@@H](CSCO)C(=O)NCC(O)=O)C(O)=O
 alt_id: CHEBI:34963;   CHEBI:40619
 xref: CAS:32260-87-0;   KEGG:C14180
 xref_mesh: MESH:C029469
 xref: PDBeChem:AHE
 cyclic_relationship: is_conjugate_acid_of CHEBI:58758


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S-(hydroxymethyl)glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases oxidation
multiple interactions		 ISO ADH5 protein results in increased oxidation of S-hydroxymethylglutathione
Cimetidine inhibits the reaction [ADH5 protein results in increased oxidation of S-hydroxymethylglutathione]		 CTD PMID:23220590 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      chemical role 19420
        antioxidant 16122
          glutathione 383
            glutathione derivative 58
              S-substituted glutathione 6
                S-(hydroxymethyl)glutathione 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      carboacyl group 17677
                                        univalent carboacyl group 17677
                                          carbamoyl group 17526
                                            carboxamide 17526
                                              peptide 11122
                                                oligopeptide 1339
                                                  tripeptide 972
                                                    glutathione 383
                                                      glutathione derivative 58
                                                        S-substituted glutathione 6
                                                          S-(hydroxymethyl)glutathione 1
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