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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chloroquine
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Accession:CHEBI:3638 term browser browse the term
Definition:An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Synonyms:exact_synonym: N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine
 related_synonym: Aralen;   Artrichin;   Bemaphate;   Capquin;   Chlorochin;   Formula=C18H26ClN3;   InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);   InChIKey=WHTVZRBIWZFKQO-UHFFFAOYSA-N;   N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine;   Nivaquine B;   Resoquine;   Reumachlor;   SMILES=CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12;   Sanoquin;   chloroquinum;   cloroquina
 xref: CAS:54-05-7;   DrugBank:DB00608;   Drug_Central:607;   Gmelin:781126;   HMDB:HMDB0014746;   KEGG:C07625;   KEGG:D02366;   LINCS:LSM-1901
 xref_mesh: MESH:D002738
 xref: PDBeChem:CLQ;   PMID:11198399;   PMID:17594118;   PMID:18052874;   PMID:19426658;   PMID:23288916;   PMID:23580861;   PMID:23635029;   PMID:23644906;   PMID:23706562;   PMID:23852712;   PMID:23891850;   PMID:25285162;   Patent:DE683692;   Patent:US2233970;   Reaxys:482809;   Wikipedia:Chloroquine
 cyclic_relationship: is_conjugate_base_of CHEBI:149484

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Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        inhibitor 0
          autophagy inhibitor 0
            chloroquine 0
              (R)-chloroquine 0
              (S)-chloroquine 0
              chloroquine sulfate 0
              hydroxychloroquine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    main group molecular entity 0
                      s-block molecular entity 0
                        hydrogen molecular entity 0
                          hydrides 0
                            inorganic hydride 0
                              pnictogen hydride 0
                                nitrogen hydride 0
                                  azane 0
                                    ammonia 0
                                      organic amino compound 0
                                        aromatic amine 0
                                          aminoquinoline 0
                                            chloroquine 0
                                              (R)-chloroquine 0
                                              (S)-chloroquine 0
                                              chloroquine sulfate 0
                                              hydroxychloroquine 0
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