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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aminoquinoline
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Accession:CHEBI:36709 term browser browse the term
Definition:Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups.
Synonyms:related_synonym: aminoquinolines


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2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO amiridine results in decreased activity of ACHE protein CTD PMID:9228650 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO amiridine results in decreased activity of BCHE protein CTD PMID:9228650 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
6-anilino-5,8-quinolinedione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO 6-anilino-5,8-quinolinedione inhibits the reaction [sodium bichromate results in increased ubiquitination of BCL2 protein]
6-anilino-5,8-quinolinedione results in decreased expression of BCL2 protein
CTD PMID:18544562 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases response to substance ISO BDNF protein results in decreased susceptibility to 6-anilino-5,8-quinolinedione CTD PMID:22261313 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP 6-anilino-5,8-quinolinedione results in increased expression of and results in increased secretion of HSP90AA1 protein CTD PMID:10617604 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP 6-anilino-5,8-quinolinedione results in increased expression of HSP90AB1 protein CTD PMID:10617604 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Il4 interleukin 4 decreases secretion ISO 6-anilino-5,8-quinolinedione results in decreased secretion of IL4 protein CTD PMID:16533816 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 decreases secretion ISO 6-anilino-5,8-quinolinedione results in decreased secretion of IL5 protein CTD PMID:16533816 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 6-anilino-5,8-quinolinedione inhibits the reaction [heat stable toxin (E coli) results in decreased expression of VEGFA protein] CTD PMID:17828804 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
amodiaquine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO Amodiaquine analog inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; Amodiaquine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] CTD PMID:29614332 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein
Amodiaquine results in increased expression of BAX protein
CTD PMID:31629065 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO Amodiaquine inhibits the reaction [Paraoxon results in decreased activity of BCHE protein] CTD PMID:29614332 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO Amodiaquine results in decreased expression of BCL2 protein
[Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein
CTD PMID:31629065 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage ISO Amodiaquine results in increased cleavage of CASP3 protein CTD PMID:31629065 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnd1 cyclin D1 affects expression ISO Amodiaquine affects the expression of CCND1 protein CTD PMID:24113242 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Amodiaquine affects the expression of CDKN1A mRNA; Amodiaquine affects the expression of CDKN1A protein CTD PMID:24113242 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 multiple interactions ISO CTLA4 protein affects the reaction [[PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]; CTLA4 protein affects the reaction [PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]] CTD PMID:29938495 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Ctsb cathepsin B decreases activity ISO Amodiaquine results in decreased activity of CTSB protein CTD PMID:24113242 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D decreases activity ISO Amodiaquine results in decreased activity of CTSD protein CTD PMID:24113242 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsl cathepsin L decreases activity ISO Amodiaquine results in decreased activity of CTSL protein CTD PMID:24113242 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
decreases response to substance
increases metabolic processing
ISO Amodiaquine results in increased activity of CYP1A1 protein
[CYP1A1 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine
CYP1A1 protein results in decreased susceptibility to Amodiaquine
CTD PMID:12451431, PMID:31629065 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases metabolic processing
multiple interactions
ISO Amodiaquine results in decreased activity of CYP1A2 protein
CYP1A2 protein results in increased metabolism of Amodiaquine
[CYP1A2 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine; [Gemfibrozil results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine; [Trimethoprim results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine
CTD PMID:11124226, PMID:26599973, PMID:31629065 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
increases metabolic processing
multiple interactions
ISO CYP1B1 protein results in decreased susceptibility to Amodiaquine
CYP1B1 protein results in increased metabolism of Amodiaquine
[CYP1B1 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine
CTD PMID:31629065 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases metabolic processing
ISO [CYP2B6 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases metabolic processing
multiple interactions
ISO CYP2C18 protein results in increased metabolism of Amodiaquine
[CYP2C18 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine
CTD PMID:31629065 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity
increases metabolic processing
multiple interactions
ISO Amodiaquine results in decreased activity of CYP2C19 protein
CYP2C19 protein results in increased metabolism of Amodiaquine
[CYP2C19 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine
CTD PMID:11124226, PMID:31629065 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions
increases response to substance
increases metabolic processing
affects metabolic processing
ISO [5-bromotryptamine analog results in decreased activity of CYP2C8 protein] which results in decreased metabolism of Amodiaquine; [5-chlorotryptamine analog results in decreased activity of CYP2C8 protein] which results in decreased metabolism of Amodiaquine; [5-fluorotryptamine analog results in decreased activity of CYP2C8 protein] which results in decreased metabolism of Amodiaquine; [CYP2C8 protein results in increased metabolism of Amodiaquine] which results in increased abundance of and results in increased secretion of desethylamodiaquine; [CYP2C8 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine; [CYP2C8 protein results in increased metabolism of Amodiaquine] which results in increased chemical synthesis of amodiaquine quinoneimine; [CYP2C8 protein results in increased metabolism of Amodiaquine] which results in increased chemical synthesis of desethylamodiaquine; [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK1 protein; [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK3 protein; [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein; [Gemfibrozil co-treated with Amodiaquine] results in decreased activity of CYP2C8 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; [Tryptamines analog results in decreased activity of CYP2C8 protein] which results in decreased metabolism of Amodiaquine; Felodipine inhibits the reaction [CYP2C8 protein results in increased metabolism of Amodiaquine]; Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]
CYP2C8 protein affects the metabolism of Amodiaquine
CTD PMID:12920490, PMID:15155557, PMID:15601807, PMID:15626586, PMID:15771232, PMID:17286541, PMID:17565714, PMID:22634058, PMID:26599973, PMID:28119166, PMID:28478157, PMID:31629065 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
multiple interactions
ISO CYP2D6 protein results in increased metabolism of Amodiaquine
[CYP2D6 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine; [CYP2D6 protein results in increased metabolism of Amodiaquine] which results in increased chemical synthesis of amodiaquine quinoneimine
CTD PMID:28478157, PMID:31629065 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases metabolic processing
ISO [CYP2E1 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing
multiple interactions
ISO CYP3A5 protein results in increased metabolism of Amodiaquine
[CYP3A5 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine
CTD PMID:31629065 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G E2f1 E2F transcription factor 1 affects expression ISO Amodiaquine affects the expression of E2F1 mRNA; Amodiaquine affects the expression of E2F1 protein CTD PMID:24113242 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; [PDCD1 protein co-treated with LAG3 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; [PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; CTLA4 protein affects the reaction [[PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]; CTLA4 protein affects the reaction [PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]]; PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]] CTD PMID:29938495 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Lag3 lymphocyte activating 3 multiple interactions ISO [PDCD1 protein co-treated with LAG3 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein] CTD PMID:29938495 NCBI chr 4:157,425,644...157,433,700
Ensembl chr 4:157,425,644...157,433,467
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK1 protein; [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK1 protein CTD PMID:31629065 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK3 protein; [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK3 protein CTD PMID:31629065 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein; [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein CTD PMID:31629065 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
multiple interactions
ISO Amodiaquine results in decreased expression of MCL1 protein
[Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein
CTD PMID:31629065 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mpo myeloperoxidase affects response to substance ISO MPO protein affects the susceptibility to Amodiaquine CTD PMID:24588327 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions ISO Amodiaquine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3] CTD PMID:29281794 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions ISO [PDCD1 protein co-treated with LAG3 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; [PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; CTLA4 protein affects the reaction [[PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]; CTLA4 protein affects the reaction [PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]]; PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]] CTD PMID:29938495 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation ISO Amodiaquine affects the phosphorylation of RB1 protein CTD PMID:24113242 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; CTLA4 protein affects the reaction [[PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]] CTD PMID:29938495 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tp53 tumor protein p53 increases activity
affects expression
ISO Amodiaquine results in increased activity of TP53 protein
Amodiaquine affects the expression of TP53 protein
CTD PMID:12082016, PMID:24113242 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
bosutinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases activity ISO bosutinib results in decreased activity of ABL1 protein CTD PMID:17114238 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases expression
ISO bosutinib results in decreased phosphorylation of AKT1 protein
bosutinib results in decreased expression of AKT1 protein
CTD PMID:17129604 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO bosutinib results in decreased expression of CCND1 protein
[SM 164 co-treated with bosutinib] results in decreased expression of CCND1 protein
CTD PMID:16489032, PMID:22241084 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 affects localization
multiple interactions
ISO bosutinib affects the localization of CCND3 protein
[bosutinib co-treated with Imatinib Mesylate] affects the localization of CCND3 protein
CTD PMID:17129604 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Cdc25a cell division cycle 25A decreases expression
multiple interactions
ISO bosutinib results in decreased expression of CDC25A protein
Imatinib Mesylate promotes the reaction [bosutinib results in decreased expression of CDC25A protein]
CTD PMID:17129604 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO bosutinib promotes the reaction [CTNNB1 protein binds to CDH1 protein]; CTNNB1 protein promotes the reaction [bosutinib results in increased stability of CDH1 protein] CTD PMID:16489032 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity
decreases expression
ISO bosutinib results in decreased activity of CDK2 protein
bosutinib results in decreased expression of CDK2 protein
CTD PMID:17129604 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO bosutinib results in increased expression of CDKN1A protein CTD PMID:17129604 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO bosutinib results in increased expression of CDKN1B protein
Imatinib Mesylate promotes the reaction [bosutinib results in increased expression of CDKN1B protein]
CTD PMID:17129604 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Csk C-terminal Src kinase decreases activity EXP bosutinib results in decreased activity of CSK protein CTD PMID:17114238 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctnnb1 catenin beta 1 affects localization
decreases phosphorylation
multiple interactions
ISO bosutinib affects the localization of CTNNB1 protein
bosutinib results in decreased phosphorylation of CTNNB1 protein
bosutinib inhibits the reaction [CTNNB1 protein binds to TCF4 protein]; bosutinib inhibits the reaction [SRC protein results in increased phosphorylation of CTNNB1 protein]; bosutinib promotes the reaction [CTNNB1 protein binds to CDH1 protein]; CTNNB1 protein promotes the reaction [bosutinib results in increased stability of CDH1 protein]
CTD PMID:16489032 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Egfr epidermal growth factor receptor decreases activity ISO bosutinib results in decreased activity of EGFR protein CTD PMID:18385429 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases phosphorylation EXP bosutinib results in decreased phosphorylation of ERBB2 protein CTD PMID:18385429 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases activity EXP bosutinib results in decreased activity of FGR protein CTD PMID:17114238 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Gpt glutamic--pyruvic transaminase increases secretion ISO bosutinib results in increased secretion of GPT protein CTD PMID:29655783 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases activity EXP bosutinib results in decreased activity of LYN protein CTD PMID:17114238 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO bosutinib inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases phosphorylation
multiple interactions
ISO bosutinib results in decreased phosphorylation of SRC protein
bosutinib inhibits the reaction [SRC protein results in increased phosphorylation of CTNNB1 protein]
CTD PMID:16489032 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO bosutinib inhibits the reaction [CTNNB1 protein binds to TCF4 protein] CTD PMID:16489032 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
chloroquine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of ABCB1 mRNA; Chloroquine results in decreased expression of ABCB1 protein
Chloroquine results in decreased expression of ABCB1A mRNA
[Chloroquine co-treated with Bortezomib] results in decreased expression of ABCB1A protein; Bortezomib promotes the reaction [Chloroquine results in decreased expression of ABCB1A mRNA]; Bortezomib promotes the reaction [Chloroquine results in decreased expression of and results in increased nitrosation of ABCB1A protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in decreased expression of ABCB1A protein]; Chloroquine promotes the reaction [Bortezomib results in decreased expression of ABCB1A mRNA]; Chloroquine promotes the reaction [Bortezomib results in decreased expression of and results in increased nitrosation of ABCB1A protein]; Chloroquine results in decreased expression of and results in increased nitrosation of ABCB1A protein; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in decreased expression of ABCB1A protein]]
Bortezomib promotes the reaction [Chloroquine results in decreased expression of ABCB1 mRNA]; Bortezomib promotes the reaction [Chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein]; Chloroquine promotes the reaction [Bortezomib results in decreased expression of ABCB1 mRNA]; Chloroquine promotes the reaction [Bortezomib results in decreased expression of and results in increased nitrosation of ABCB1 protein]; Chloroquine promotes the reaction [Cisplatin results in decreased expression of ABCB1 mRNA]; Chloroquine promotes the reaction [Cisplatin results in decreased expression of ABCB1 protein]; Chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein
CTD PMID:25987058, PMID:27692344, PMID:30482226 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression ISO Chloroquine results in decreased expression of ABCC1 mRNA; Chloroquine results in decreased expression of ABCC1 protein CTD PMID:27692344 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Chloroquine results in decreased expression of ABCC2 mRNA; Chloroquine results in decreased expression of ABCC2 protein CTD PMID:27692344 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression ISO Chloroquine results in decreased expression of ABCG2 mRNA; Chloroquine results in decreased expression of ABCG2 protein CTD PMID:27692344 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
Chloroquine inhibits the reaction [formosanin C results in decreased phosphorylation of AKT1 protein]
Chloroquine results in decreased phosphorylation of AKT1 protein
Chloroquine inhibits the reaction [[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of and results in increased phosphorylation of AKT1 protein]
CTD PMID:24990399, PMID:27180204 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions EXP Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] CTD PMID:22689575 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP Chloroquine results in decreased expression of ALDH1B1 mRNA CTD PMID:19393257 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Angptl8 angiopoietin-like 8 multiple interactions ISO Chloroquine inhibits the reaction [ANGPTL8 protein results in decreased expression of SQSTM1 protein] CTD PMID:24262987 NCBI chr 8:22,855,495...22,858,565
Ensembl chr 8:22,856,539...22,858,565
JBrowse link
G Apod apolipoprotein D affects localization ISO Chloroquine affects the localization of APOD protein CTD PMID:28182653 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Apoe apolipoprotein E affects localization EXP Chloroquine affects the localization of APOE protein CTD PMID:8616629 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein affects expression
multiple interactions
affects localization
increases expression
EXP Chloroquine affects the expression of APP mRNA; Chloroquine affects the expression of APP protein
Chloroquine affects the localization of and affects the cleavage of APP protein
Chloroquine affects the localization of APP protein
Chloroquine results in increased expression of APP protein
CTD PMID:7715800, PMID:8616629, PMID:8787835, PMID:9690670 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO Chloroquine inhibits the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Aqp2 aquaporin 2 decreases degradation
multiple interactions
decreases expression
ISO Chloroquine results in decreased degradation of AQP2 protein
Chloroquine inhibits the reaction [AVP protein affects the localization of AQP2 protein]
Chloroquine results in decreased expression of AQP2 protein
CTD PMID:21734099, PMID:22791344 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO Chloroquine inhibits the reaction [Cyclic AMP results in decreased expression of AQP5 protein] CTD PMID:15536076 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Ar androgen receptor multiple interactions ISO Chloroquine inhibits the reaction [Riluzole results in increased degradation of and results in decreased expression of AR protein alternative form]; Chloroquine inhibits the reaction [Riluzole results in increased degradation of and results in decreased expression of AR protein] CTD PMID:30280407 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arcn1 archain 1 affects localization ISO Chloroquine affects the localization of ARCN1 protein CTD PMID:29940786 NCBI chr 8:49,051,257...49,075,861
Ensembl chr 8:49,051,246...49,075,892
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP Chloroquine results in decreased expression of ASS1 mRNA CTD PMID:19393257 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP Chloroquine promotes the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29870746 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO
EXP
Chloroquine inhibits the reaction [hydroxyethyl methacrylate results in increased expression of ATG5 protein]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased expression of ATG5 protein]
Chloroquine results in increased expression of ATG5 protein
Chloroquine inhibits the reaction [cadmium acetate results in increased expression of ATG5 protein]
CTD PMID:28184909, PMID:29870746, PMID:30338810 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation ISO Chloroquine results in increased phosphorylation of ATM protein CTD PMID:18089834 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions
increases expression
EXP
ISO
Chloroquine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein]
Chloroquine results in increased expression of ATP1A1 protein
CTD PMID:10506578, PMID:26750564 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Avp arginine vasopressin multiple interactions ISO Chloroquine inhibits the reaction [AVP protein affects the localization of AQP2 protein]; Chloroquine inhibits the reaction [AVP protein affects the localization of SLC14A2 protein] CTD PMID:22791344 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
BAX mutant form inhibits the reaction [Chloroquine results in increased activity of CASP3 protein]
Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]]
Chloroquine affects the folding of and results in increased activity of BAX protein; Chloroquine inhibits the reaction [formosanin C results in increased expression of BAX protein]; Chloroquine promotes the reaction [dactolisib affects the folding of and results in increased activity of BAX protein]; dactolisib promotes the reaction [Chloroquine affects the folding of and results in increased activity of BAX protein]
CTD PMID:11589424, PMID:23151917, PMID:27180204, PMID:28713934 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Chloroquine results in increased expression of BBC3 mRNA CTD PMID:31310755 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP
Chloroquine inhibits the reaction [formosanin C results in decreased expression of BCL2 protein]
Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]
CTD PMID:27180204, PMID:28713934 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
ISO BCL2L1 mutant form promotes the reaction [Chloroquine results in increased activity of CASP3 protein]
Chloroquine results in increased expression of BCL2L1 mRNA
CTD PMID:11589424, PMID:31310755 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
ISO
EXP
Carboplatin promotes the reaction [Chloroquine results in decreased expression of BECN1 protein]; Chloroquine inhibits the reaction [Cisplatin results in increased expression of BECN1 protein]; Chloroquine inhibits the reaction [hydroxyethyl methacrylate results in increased expression of BECN1 protein]; Chloroquine promotes the reaction [Carboplatin results in decreased expression of BECN1 protein]
Chloroquine promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BECN1 protein]
Chloroquine inhibits the reaction [cadmium acetate results in increased expression of BECN1 protein]
Chloroquine results in decreased expression of BECN1 mRNA; Chloroquine results in decreased expression of BECN1 protein
CTD PMID:25987058, PMID:27692344, PMID:28184909, PMID:29870746, PMID:31862506 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Chloroquine inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Chloroquine promotes the reaction [sunitinib results in decreased expression of BIRC5 protein]
Chloroquine promotes the reaction [Immunologic Factors results in decreased expression of BIRC5 protein]
CTD PMID:24751611, PMID:27823620 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
increases expression
ISO vistusertib inhibits the reaction [Chloroquine results in increased expression of BNIP3 protein] CTD PMID:26853465 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Calr calreticulin increases expression
multiple interactions
ISO Chloroquine results in increased expression of CALR mRNA
[CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of and affects the localization of CALR protein]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of CALR mRNA]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [Chloroquine results in increased expression of and affects the localization of CALR protein]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [Chloroquine results in increased expression of CALR mRNA]; [Chloroquine co-treated with Bortezomib] promotes the reaction [CEBPB protein alternative form binds to CALR promoter]; [Chloroquine co-treated with Bortezomib] results in increased expression of and affects the localization of CALR protein; [Chloroquine co-treated with Bortezomib] results in increased expression of CALR mRNA; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of and affects the localization of CALR protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR mRNA]; CEBPB protein alternative form promotes the reaction [Chloroquine results in increased expression of and affects the localization of CALR protein]; CEBPB protein alternative form promotes the reaction [Chloroquine results in increased expression of CALR mRNA]; Chloroquine promotes the reaction [CEBPB protein alternative form binds to CALR promoter]; Chloroquine results in increased expression of and affects the localization of CALR protein; DDIT3 protein affects the reaction [[Chloroquine co-treated with Bortezomib] affects the localization of CALR protein]; DDIT3 protein affects the reaction [Chloroquine affects the localization of CALR protein]; Doxorubicin promotes the reaction [[Chloroquine co-treated with Bortezomib] affects the localization of CALR protein]; Doxorubicin promotes the reaction [Chloroquine affects the localization of CALR protein]
[Chloroquine co-treated with Bortezomib] results in increased expression of CALR protein; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR protein]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR protein]]
CTD PMID:30482226 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp12 caspase 12 multiple interactions EXP Chloroquine promotes the reaction [cadmium acetate results in increased expression of CASP12 protein] CTD PMID:29870746 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [Chloroquine results in increased cleavage of CASP3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased cleavage of CASP3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased cleavage of CASP3 protein]; [Bortezomib co-treated with Chloroquine] results in increased cleavage of CASP3 protein; [Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein; [Rotenone co-treated with Chloroquine] results in increased cleavage of CASP3 protein; BAX mutant form inhibits the reaction [Chloroquine results in increased activity of CASP3 protein]; BCL2L1 mutant form promotes the reaction [Chloroquine results in increased activity of CASP3 protein]; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]]; Chloroquine promotes the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Chloroquine promotes the reaction [Sunitinib results in increased activity of CASP3 protein]; Doxorubicin promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased cleavage of CASP3 protein]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]]; Doxorubicin promotes the reaction [Chloroquine results in increased cleavage of CASP3 protein]; Nitroprusside promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; Nitroprusside promotes the reaction [Chloroquine results in increased cleavage of CASP3 protein]; TRP53 mutant form inhibits the reaction [Chloroquine results in increased activity of CASP3 protein]
Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]]; Chloroquine inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]]
Chloroquine results in increased expression of CASP3 protein
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [Chloroquine results in increased cleavage of CASP3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased cleavage of CASP3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased cleavage of CASP3 protein]; [aloxistatin co-treated with pepstatin] inhibits the reaction [[vistusertib co-treated with Chloroquine] results in increased activity of CASP3 protein]; [Bortezomib co-treated with Chloroquine] results in increased cleavage of CASP3 protein; [capivasertib co-treated with Chloroquine] results in increased activity of CASP3 protein; [Chloroquine co-treated with N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine] results in increased activity of CASP3 protein; [vistusertib co-treated with Chloroquine] results in increased activity of CASP3 protein; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [[capivasertib co-treated with Chloroquine] results in increased activity of CASP3 protein]; CA 074 methyl ester inhibits the reaction [[vistusertib co-treated with Chloroquine] results in increased activity of CASP3 protein]; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; Chloroquine inhibits the reaction [Biological Products results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [formosanin C results in increased expression of and results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Biological Products results in increased expression of and results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Cisplatin results in increased expression of CASP3 protein]; Chloroquine promotes the reaction [dactolisib results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [usnic acid results in increased activity of CASP3 protein]; dactolisib promotes the reaction [Chloroquine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Chloroquine results in increased cleavage of CASP3 protein]; Doxorubicin promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; Doxorubicin promotes the reaction [Chloroquine results in increased cleavage of CASP3 protein]; NDRG1 protein affects the reaction [Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]]; NDRG1 protein affects the reaction [Chloroquine results in increased cleavage of CASP3 protein]; Nitroprusside promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; Nitroprusside promotes the reaction [Chloroquine results in increased cleavage of CASP3 protein]
CTD PMID:11589424, PMID:23151917, PMID:23799852, PMID:24751611, PMID:25078063, PMID:25266202, PMID:25987058, PMID:26847702, PMID:26853465, PMID:27180204, PMID:28219700, PMID:28906492, PMID:29111403, PMID:29476062, PMID:30338810, PMID:30465897, PMID:30482226, PMID:30985881, PMID:31332898, PMID:31676321, PMID:32651653 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Chloroquine promotes the reaction [usnic acid results in increased activity of CASP7 protein] CTD PMID:25078063 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO Chloroquine results in increased cleavage of CASP8 protein
Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP8 protein]
Chloroquine inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD PMID:27692344, PMID:28906492, PMID:29111403 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO [Chloroquine co-treated with N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine] results in increased activity of CASP9 protein; Chloroquine inhibits the reaction [hydroxyethyl methacrylate results in increased expression of CASP9 mRNA]; Chloroquine promotes the reaction [dactolisib results in increased cleavage of CASP9 protein]; Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP9 protein]; dactolisib promotes the reaction [Chloroquine results in increased cleavage of CASP9 protein] CTD PMID:23151917, PMID:23799852, PMID:28184909, PMID:28906492 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression
EXP
ISO
Chloroquine results in decreased activity of CAT protein
Chloroquine promotes the reaction [sunitinib results in increased activity of CAT protein]; Quercetin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Chloroquine results in decreased expression of CAT mRNA]
Curcumin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]; tetrahydrocurcumin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]
Chloroquine results in decreased expression of CAT protein
CTD PMID:15526909, PMID:17076682, PMID:23607047, PMID:24751611 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL1 protein] CTD PMID:22341560 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases secretion
multiple interactions
ISO Chloroquine results in decreased secretion of CCL11 protein
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL11 protein]
CTD PMID:22341560, PMID:29772762 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
decreases secretion
ISO Chloroquine results in increased expression of CCL2 mRNA
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL2 protein]
Chloroquine results in decreased secretion of CCL2 protein
Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; diphenyliodonium inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]
CTD PMID:15139008, PMID:22341560, PMID:29772762 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL25 protein] CTD PMID:22341560 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL5 protein] CTD PMID:22341560 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression EXP Chloroquine results in increased expression of CCN1 mRNA CTD PMID:19393257 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Cd274 CD274 molecule decreases expression ISO Chloroquine results in decreased expression of CD274 protein CTD PMID:27692344 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd34 CD34 molecule multiple interactions ISO Chloroquine promotes the reaction [sunitinib results in decreased expression of CD34 protein] CTD PMID:24751611 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP Chloroquine inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 mRNA]; Chloroquine inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 protein] CTD PMID:30053495 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP Chloroquine inhibits the reaction [Dibutyl Phthalate results in increased expression of CDH2 mRNA]; Chloroquine inhibits the reaction [Dibutyl Phthalate results in increased expression of CDH2 protein] CTD PMID:30053495 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases activity
multiple interactions
increases expression
ISO Chloroquine results in increased activity of CDKN1A
[Chloroquine co-treated with flavokawain B] results in decreased expression of CDKN1A protein; Chloroquine inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]
Chloroquine results in increased expression of CDKN1A protein
CTD PMID:12243503, PMID:18089834, PMID:22927544, PMID:30025493 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression
ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of CEBPB protein alternative form]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased expression of CEBPB protein alternative form]; [Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in decreased expression of ABCB1A protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of IFNG protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of MKI67 protein]; Doxorubicin promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in decreased expression of ABCB1A protein]]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR protein]]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of IFNG protein]]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of MKI67 protein]]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of CEBPB protein alternative form]
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of CEBPB protein alternative form]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of CEBPB protein alternative form]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased expression of CEBPB protein alternative form]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of and affects the localization of CALR protein]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of CALR mRNA]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [Chloroquine results in increased expression of and affects the localization of CALR protein]; [CEBPB protein alternative form results in increased susceptibility to Doxorubicin] promotes the reaction [Chloroquine results in increased expression of CALR mRNA]; [Chloroquine co-treated with Bortezomib] promotes the reaction [CEBPB protein alternative form binds to CALR promoter]; [Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of and affects the localization of CALR protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CALR mRNA]; CEBPB protein alternative form promotes the reaction [Chloroquine results in increased expression of and affects the localization of CALR protein]; CEBPB protein alternative form promotes the reaction [Chloroquine results in increased expression of CALR mRNA]; Chloroquine promotes the reaction [CEBPB protein alternative form binds to CALR promoter]; Doxorubicin promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of CEBPB protein alternative form]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of CEBPB protein alternative form]
CTD PMID:30482226 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex decreases expression ISO Chloroquine results in decreased expression of CHUK protein CTD PMID:26116531 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cip2a cellular inhibitor of PP2A multiple interactions ISO Chloroquine inhibits the reaction [temsirolimus results in decreased expression of CIP2A protein] CTD PMID:24493623 NCBI chr11:54,373,794...54,404,704
Ensembl chr11:54,377,374...54,404,612
JBrowse link
G Cldn1 claudin 1 increases expression ISO Chloroquine results in increased expression of CLDN1 mRNA CTD PMID:25752684 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn2 claudin 2 multiple interactions ISO Chloroquine inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein] CTD PMID:29597147 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Clu clusterin affects localization EXP Chloroquine affects the localization of CLU protein CTD PMID:8616629 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Coq6 coenzyme Q6 monooxygenase decreases expression EXP Chloroquine results in decreased expression of COQ6 mRNA CTD PMID:19393257 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO Chloroquine promotes the reaction [Triiodothyronine results in increased expression of COX4I1 protein] CTD PMID:30209975 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP Chloroquine inhibits the reaction [Dibutyl Phthalate results in increased expression of CTNNB1 mRNA] CTD PMID:30053495 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctrb1 chymotrypsinogen B1 decreases expression EXP Chloroquine results in decreased expression of CTRB1 mRNA CTD PMID:19393257 NCBI chr19:43,906,344...43,911,020
Ensembl chr19:43,906,292...43,911,057
JBrowse link
G Ctsb cathepsin B increases expression
decreases activity
multiple interactions
EXP
ISO
Chloroquine results in increased expression of CTSB protein
Chloroquine results in decreased activity of CTSB protein
[Chloroquine co-treated with dactolisib] affects the localization of CTSB protein; Chloroquine inhibits the reaction [Arsenic Trioxide results in increased activity of CTSB protein]
CTD PMID:2759144, PMID:23151917, PMID:30338810 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D affects localization
increases expression
EXP Chloroquine affects the localization of CTSD protein
Chloroquine results in increased expression of CTSD protein
CTD PMID:2759144, PMID:7715800 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsl cathepsin L increases expression EXP Chloroquine results in increased expression of CTSL protein CTD PMID:2759144 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Chloroquine inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; Chloroquine inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL12 protein] CTD PMID:22341560 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL9 protein] CTD PMID:22341560 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Chloroquine results in decreased expression of CYP11A1 mRNA CTD PMID:19393257 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Chloroquine results in decreased expression of CYP17A1 mRNA CTD PMID:19393257 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Chloroquine inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine] CTD PMID:7946932 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects metabolic processing
multiple interactions
increases metabolic processing
ISO CYP2C8 polymorphism affects the metabolism of Chloroquine; CYP2C8 protein affects the metabolism of Chloroquine
[CYP2C8 protein results in increased metabolism of Chloroquine] which results in increased abundance of desethylchloroquine; Quercetin inhibits the reaction [[CYP2C8 protein results in increased metabolism of Chloroquine] which results in increased abundance of desethylchloroquine]
CTD PMID:12756207, PMID:12920490, PMID:12967198, PMID:17286541, PMID:19560616 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing
decreases activity
multiple interactions
ISO CYP2D6 protein affects the metabolism of Chloroquine
Chloroquine results in decreased activity of CYP2D6 protein
[CYP2D6 protein results in increased metabolism of Chloroquine] which results in increased abundance of desethylchloroquine
CTD PMID:12756207, PMID:12920490 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO Chloroquine promotes the reaction [CYP7A1 protein results in increased expression of MAP1LC3B protein modified form]; CYP7A1 mRNA promotes the reaction [Chloroquine results in increased expression of MAP1LC3B protein modified form] CTD PMID:28275691 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
Chloroquine promotes the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Chloroquine promotes the reaction [Cadmium results in increased expression of DDIT3 protein]
Chloroquine results in increased expression of DDIT3 protein
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased expression of DDIT3 protein]; [Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [[Chloroquine co-treated with Bortezomib] affects the localization of CALR protein]; DDIT3 protein affects the reaction [[Chloroquine co-treated with Bortezomib] results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Chloroquine affects the localization of CALR protein]; DDIT3 protein affects the reaction [Chloroquine results in increased cleavage of CASP3 protein]; Doxorubicin promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of DDIT3 protein]; Nitroprusside promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; Nitroprusside promotes the reaction [Chloroquine results in increased expression of DDIT3 protein]
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased expression of DDIT3 protein]; [Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein; [Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; Doxorubicin promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of DDIT3 protein]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of DDIT3 protein]; Nitroprusside inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of DDIT3 protein]; Nitroprusside inhibits the reaction [Chloroquine results in increased expression of DDIT3 protein]
CTD PMID:27658547, PMID:29870746, PMID:30482226 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eea1 early endosome antigen 1 affects localization ISO Chloroquine affects the localization of EEA1 protein CTD PMID:29940786 NCBI chr 7:37,101,415...37,186,534
Ensembl chr 7:37,018,459...37,186,732
JBrowse link
G Egf epidermal growth factor multiple interactions ISO
EXP
Chloroquine inhibits the reaction [EGF protein results in decreased expression of EGFR protein]
Chloroquine inhibits the reaction [EGF protein results in increased expression of RHEB protein]; Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Chloroquine promotes the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein]
CTD PMID:20332299, PMID:22689575 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
ISO
EXP
Chloroquine inhibits the reaction [EGF protein results in decreased expression of EGFR protein]; Chloroquine inhibits the reaction [MUC1 affects the expression of EGFR protein]; Chloroquine inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]; Chloroquine inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein]; Chloroquine inhibits the reaction [tephrosin results in increased degradation of EGFR protein]
Chloroquine promotes the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein]
Chloroquine results in decreased expression of EGFR protein
CTD PMID:20056314, PMID:20332299, PMID:22457794, PMID:22689575 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eno2 enolase 2 multiple interactions EXP Chloroquine inhibits the reaction [Sirolimus results in increased expression of ENO2 protein] CTD PMID:26676567 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of ERBB2 protein
Chloroquine inhibits the reaction [tephrosin results in increased degradation of ERBB2 protein]
CTD PMID:20056314, PMID:20332299 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Chloroquine results in decreased expression of ERBB3 protein CTD PMID:20332299 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Ergic3 ERGIC and golgi 3 multiple interactions ISO ERGIC3 protein promotes the reaction [Chloroquine results in increased expression of SQSTM1 protein] CTD PMID:27588471 NCBI chr 3:151,553,567...151,563,318
Ensembl chr 3:151,553,578...151,563,364
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP Chloroquine results in decreased expression of FADS2 mRNA CTD PMID:19393257 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Faslg Fas ligand multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of FASL protein] CTD PMID:22341560 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxo32 F-box protein 32 affects expression EXP Chloroquine affects the expression of FBXO32 mRNA CTD PMID:19296457 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions EXP Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in decreased expression of FGF1 mRNA]] CTD PMID:31332898 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fmn1 formin 1 decreases expression EXP Chloroquine results in decreased expression of FMN1 mRNA CTD PMID:19393257 NCBI chr 3:104,783,093...105,170,761
Ensembl chr 3:104,816,987...105,086,436
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression
ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of FTH1 mRNA]
Chloroquine results in increased expression of FTH1 mRNA
CTD PMID:30551460 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fundc1 FUN14 domain containing 1 multiple interactions ISO Chloroquine inhibits the reaction [Rotenone results in decreased expression of FUNDC1 protein] CTD PMID:32001317 NCBI chr  X:5,549,468...5,566,125
Ensembl chr  X:5,549,419...5,566,127
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 multiple interactions ISO GAL3ST1 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein] CTD PMID:23880069 NCBI chr14:84,231,473...84,247,371
Ensembl chr14:84,231,639...84,247,369
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP
ISO
Chloroquine inhibits the reaction [DDT results in increased degradation of GJA1 protein modified form]; Chloroquine inhibits the reaction [Hexachlorocyclohexane results in increased degradation of GJA1 protein modified form]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of GJA1 protein]]; Chloroquine promotes the reaction [Glucose results in increased expression of GJA1 protein]
Chloroquine inhibits the reaction [LAMB1 protein affects the localization of GJA1 protein]
CTD PMID:8824497, PMID:22150760, PMID:28713934 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression EXP Chloroquine results in decreased expression of GJB2 mRNA CTD PMID:19393257 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO [Chloroquine co-treated with flavokawain B] results in decreased expression of GLB1 protein CTD PMID:30025493 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP Chloroquine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] CTD PMID:22925809 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Golga2 golgin A2 affects localization ISO Chloroquine affects the localization of GOLGA2 protein CTD PMID:29940786 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Chloroquine results in increased expression of GPNMB mRNA CTD PMID:19393257 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr182 G protein-coupled receptor 182 decreases expression EXP Chloroquine results in decreased expression of GPR182 mRNA CTD PMID:19393257 NCBI chr 7:71,044,786...71,048,713
Ensembl chr 7:71,045,543...71,048,383
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Chloroquine inhibits the reaction [resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased activity of GPT protein]]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased activity of GPT protein] CTD PMID:26498332 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of GPX4 mRNA
Quercetin inhibits the reaction [Chloroquine results in decreased expression of GPX4 mRNA]
CTD PMID:23607047 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP Chloroquine inhibits the reaction [Nanotubes, Carbon results in decreased expression of GRIN2B] CTD PMID:26327526 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
decreases expression
multiple interactions
ISO Chloroquine results in decreased activity of GSR protein
Chloroquine results in decreased expression of GSR mRNA
Quercetin inhibits the reaction [Chloroquine results in decreased activity of GSR protein]; Quercetin inhibits the reaction [Chloroquine results in decreased expression of GSR mRNA]
CTD PMID:23607047 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hbg1 hemoglobin subunit gamma 1 decreases expression EXP Chloroquine results in decreased expression of HBG1 mRNA CTD PMID:19393257 NCBI chr 1:168,992,841...168,994,219
Ensembl chr 1:168,992,722...168,994,253
JBrowse link
G Hmbs hydroxymethylbilane synthase increases response to substance ISO HMBS mutant form results in increased susceptibility to Chloroquine CTD PMID:8772850 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased expression of HSPA1B protein] CTD PMID:17046822 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Chloroquine promotes the reaction [cadmium acetate results in increased expression of HSPA5 protein] CTD PMID:29870746 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Chloroquine inhibits the reaction [resveratrol inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] CTD PMID:24145604 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 protein]] CTD PMID:28134560 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA
[Chloroquine co-treated with Bortezomib] results in increased expression of IFNG protein; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of IFNG protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IFNG protein]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of IFNG protein]]
CTD PMID:22341560, PMID:29594315, PMID:30482226 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases expression ISO Chloroquine results in decreased expression of IKBKB protein CTD PMID:26116531 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma decreases expression ISO Chloroquine results in decreased expression of IKBKG protein CTD PMID:26116531 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL10 protein] CTD PMID:22341560 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL13 protein] CTD PMID:22341560 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il17a interleukin 17A multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL17A protein] CTD PMID:22341560 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Chloroquine results in increased expression of IL1A
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1A protein]
CTD PMID:15139008, PMID:22341560 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
multiple interactions
ISO Chloroquine results in increased expression of IL1B
Chloroquine results in decreased expression of IL1B mRNA
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL1B protein]]; Chloroquine inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL1B mRNA]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL1B protein]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]]; Chloroquine inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]
CTD PMID:15139008, PMID:21051542, PMID:22341560, PMID:26498332, PMID:29594315, PMID:31648047 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of IL2 mRNA; Chloroquine results in decreased expression of IL2 protein
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL2 protein]
[Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA
CTD PMID:7554381, PMID:22341560, PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL3 protein] CTD PMID:22341560 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL4 protein] CTD PMID:22341560 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
decreases secretion
increases expression
ISO
EXP
Chloroquine results in decreased expression of IL6 protein
Chloroquine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]]
Chloroquine results in decreased secretion of IL6 protein
Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of IL6 protein]]
[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]; Bortezomib inhibits the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 protein]]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 mRNA]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]]
Chloroquine results in increased expression of IL6
CTD PMID:9002011, PMID:9799232, PMID:10638776, PMID:15139008, PMID:22341560, PMID:26498332, PMID:28134560, PMID:29772762, PMID:31332898, PMID:31648047 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of IRF3 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of IRF3 protein]; Chloroquine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of IRF3 protein]] CTD PMID:22341560, PMID:25780039, PMID:28134560 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog co-treated with Chloroquine] inhibits the reaction [Tretinoin affects the localization of ITGAM protein]; Chloroquine inhibits the reaction [Tretinoin affects the localization of ITGAM protein] CTD PMID:29743969 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO Chloroquine inhibits the reaction [LAMB1 protein affects the localization of GJA1 protein] CTD PMID:22150760 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lcn2 lipocalin 2 increases expression EXP Chloroquine results in increased expression of LCN2 mRNA CTD PMID:19393257 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO Chloroquine affects the reaction [SORT1 protein affects the reaction [LDLR protein affects the abundance of Cholesterol]] CTD PMID:30950489 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of LEP protein] CTD PMID:22341560 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor increases expression ISO Chloroquine results in increased expression of LEPR protein CTD PMID:31199479 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Ltb lymphotoxin beta increases expression ISO Chloroquine results in increased expression of LTB CTD PMID:15139008 NCBI chr20:5,184,631...5,186,476
Ensembl chr20:5,184,515...5,186,503
JBrowse link
G M6pr mannose-6-phosphate receptor, cation dependent affects expression
affects localization
EXP
ISO
Chloroquine affects the expression of M6PR mRNA
Chloroquine affects the localization of M6PR protein
CTD PMID:15712280, PMID:29940786 NCBI chr 4:155,084,755...155,093,896
Ensembl chr 4:155,088,317...155,092,827
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression ISO Chloroquine results in increased expression of MAP1LC3A protein; Chloroquine results in increased expression of MAP1LC3A protein modified form CTD PMID:30280407, PMID:30871063 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
increases lipidation
multiple interactions
affects localization
increases cleavage
EXP
ISO
Chloroquine results in increased expression of MAP1LC3B mRNA; Chloroquine results in increased expression of MAP1LC3B protein; Chloroquine results in increased expression of MAP1LC3B protein modified form
Chloroquine results in increased lipidation of MAP1LC3B protein
Chloroquine promotes the reaction [Cisplatin results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [trichostatin A results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [Vorinostat results in increased expression of MAP1LC3B protein modified form]
Chloroquine affects the localization of MAP1LC3B protein
Chloroquine results in increased cleavage of MAP1LC3B protein
[Ethanol co-treated with Chloroquine] results in increased lipidation of MAP1LC3B protein; Chloroquine inhibits the reaction [VCP protein mutant form results in decreased expression of MAP1LC3B protein]; Chloroquine promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased lipidation of MAP1LC3B protein]
[Chloroquine co-treated with flavokawain B] results in increased expression of MAP1LC3B protein modified form; [Chloroquine co-treated with TNF protein] results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; Chloroquine affects the reaction [NDRG1 protein affects the lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline affects the localization of MAP1LC3B protein]; Chloroquine promotes the reaction [[Simvastatin co-treated with Metformin] results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [[TNF protein co-treated with Resveratrol] results in increased expression of MAP1LC3B protein alternative form]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B protein]; Chloroquine promotes the reaction [CYP7A1 protein results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [Ethanol results in increased expression of MAP1LC3B protein]; Chloroquine promotes the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [fosbretabulin results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [Rifampin results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [YM 155 results in increased lipidation of MAP1LC3B protein]; Chloroquine results in increased lipidation of and results in increased cleavage of MAP1LC3B protein; cryptotanshinone promotes the reaction [Chloroquine results in increased expression of MAP1LC3B protein]; CYP7A1 mRNA promotes the reaction [Chloroquine results in increased expression of MAP1LC3B protein modified form]; GAL3ST1 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; NDRG1 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; NOD2 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; Paraquat inhibits the reaction [Chloroquine results in increased expression of MAP1LC3B protein modified form]
CTD PMID:17643062, PMID:23880069, PMID:24095927, PMID:24145604, PMID:24161432, PMID:24492484, PMID:25412314, PMID:25884947, PMID:26409479, PMID:28275691, PMID:28600121, PMID:28722353, PMID:28906492, PMID:29248574, PMID:29476062, PMID:30025493, PMID:30208301, PMID:30237538, PMID:30338810, PMID:31310755, PMID:31586597, PMID:31648047, PMID:31837377, PMID:31862506 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions EXP Chloroquine inhibits the reaction [Sirolimus results in increased expression of MAP2 protein] CTD PMID:26676567 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Chloroquine results in increased phosphorylation of MAPK1 protein
Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]]
CTD PMID:18055026, PMID:22341560, PMID:28134560, PMID:31310755 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]]
Chloroquine results in increased phosphorylation of MAPK3 protein
CTD PMID:18055026, PMID:22341560, PMID:28134560, PMID:31310755 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]]; Chloroquine promotes the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]
CTD PMID:22341560, PMID:28134560, PMID:31648047 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapt microtubule-associated protein tau affects expression
multiple interactions
EXP Chloroquine affects the expression of MAPT mRNA; Chloroquine affects the expression of MAPT protein
Chloroquine affects the localization of and affects the degradation of MAPT protein
CTD PMID:9690670 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO Chloroquine promotes the reaction [usnic acid results in decreased expression of MCL1 protein] CTD PMID:25078063 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mir155 microRNA 155 multiple interactions ISO [Carboplatin co-treated with Chloroquine] results in increased expression of MIR155 mRNA CTD PMID:27692344 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir224 microRNA 224 ISO inhibits the reaction [Amiodarone decreased expression of miR224 in a human hepatoma cell line] RGD PMID:23913306 RGD:18182923 NCBI chr  X:152,223,754...152,223,835
Ensembl chr  X:152,223,754...152,223,835
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Chloroquine co-treated with flavokawain B] results in decreased expression of MKI67 protein
[Chloroquine co-treated with Bortezomib] results in increased expression of MKI67 protein; CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of MKI67 protein]; Doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of MKI67 protein]]
CTD PMID:30025493, PMID:30482226 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
increases expression
ISO Oxygen deficiency promotes the reaction [Chloroquine results in increased expression of MMP13 mRNA]; TLR9 protein promotes the reaction [Oxygen deficiency promotes the reaction [Chloroquine results in increased expression of MMP13 mRNA]]
Chloroquine results in increased expression of MMP13 mRNA; Chloroquine results in increased expression of MMP13 protein
Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased expression of MMP13 mRNA]; Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased secretion of MMP13 protein]
CTD PMID:23331101, PMID:24273604 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Chloroquine results in decreased expression of MMP2 mRNA; Chloroquine results in decreased expression of MMP2 protein CTD PMID:24273604 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
decreases expression
ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of MMP9 mRNA]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; Oxygen deficiency inhibits the reaction [Chloroquine results in decreased expression of MMP9 mRNA]
Chloroquine results in increased expression of MMP9 mRNA
Chloroquine results in decreased expression of MMP9 mRNA; Chloroquine results in decreased expression of MMP9 protein
CTD PMID:24145604, PMID:24273604, PMID:30551460 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
increases expression
ISO Chloroquine inhibits the reaction [formosanin C results in decreased phosphorylation of MTOR protein]
Chloroquine results in decreased phosphorylation of MTOR protein
Chloroquine results in increased expression of MTOR protein
CTD PMID:25884947, PMID:27180204, PMID:31310755 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions ISO Chloroquine inhibits the reaction [MUC1 affects the expression of EGFR protein] CTD PMID:22457794 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 mRNA] CTD PMID:22341560 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myom2 myomesin 2 increases expression EXP Chloroquine results in increased expression of MYOM2 mRNA CTD PMID:19393257 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Nacc1 nucleus accumbens associated 1 multiple interactions ISO Chloroquine affects the reaction [NACC1 affects the susceptibility to Cisplatin] CTD PMID:21743489 NCBI chr19:25,783,686...25,801,526
Ensembl chr19:25,783,900...25,801,526
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions
increases expression
ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of NCOA4 mRNA]
Chloroquine results in increased expression of NCOA4 mRNA
CTD PMID:30551460 NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO Chloroquine affects the reaction [NDRG1 protein affects the lipidation of MAP1LC3B protein]; Chloroquine inhibits the reaction [Cycloheximide results in decreased expression of NDRG1 protein]; Chloroquine promotes the reaction [fosbretabulin results in increased expression of NDRG1 protein]; NDRG1 protein affects the reaction [Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]]; NDRG1 protein affects the reaction [Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]]; NDRG1 protein affects the reaction [Chloroquine results in increased cleavage of CASP3 protein]; NDRG1 protein affects the reaction [Chloroquine results in increased cleavage of PARP1 protein]; NDRG1 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; NDRG1 protein affects the susceptibility to [fosbretabulin co-treated with Chloroquine] CTD PMID:28906492 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of NFKB1 protein
Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of NFKB1 protein]
CTD PMID:22341560, PMID:26116531 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]]
Chloroquine inhibits the reaction [Bortezomib results in increased degradation of NFKBIA protein]
CTD PMID:24085292, PMID:28134560 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO NOD2 protein affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein] CTD PMID:23880069 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Chloroquine promotes the reaction [sunitinib results in increased expression of NOS2 protein] CTD PMID:24751611 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 multiple interactions ISO [Fluorouracil co-treated with Chloroquine] results in increased expression of NOTCH1 protein CTD PMID:29917191 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nppc natriuretic peptide C decreases expression EXP Chloroquine results in decreased expression of NPPC mRNA CTD PMID:19393257 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions ISO Chloroquine binds to and results in decreased activity of NQO2 protein CTD PMID:15078100 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Chloroquine results in decreased expression of NR0B2 mRNA CTD PMID:24189133 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Ocln occludin increases expression ISO Chloroquine results in increased expression of OCLN mRNA CTD PMID:25752684 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Optn optineurin multiple interactions ISO Chloroquine inhibits the reaction [VCP protein mutant form results in increased expression of OPTN protein] CTD PMID:25884947 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Chloroquine results in decreased expression of OSGIN1 mRNA CTD PMID:19393257 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
EXP
ISO
Chloroquine promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]
Chloroquine results in increased cleavage of PARP1 protein
[Chloroquine co-treated with 3-methyladenine] results in increased cleavage of PARP1 protein; Arsenic Trioxide promotes the reaction [Chloroquine results in increased cleavage of PARP1 protein]; Chloroquine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; NDRG1 protein affects the reaction [Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]]; NDRG1 protein affects the reaction [Chloroquine results in increased cleavage of PARP1 protein]
CTD PMID:27658547, PMID:28906492, PMID:29111403, PMID:30025493, PMID:30338810, PMID:30985881, PMID:31310755 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Plin3 perilipin 3 multiple interactions ISO Chloroquine inhibits the reaction [CpG ODN 1826 results in increased expression of PLIN3 mRNA]; Chloroquine inhibits the reaction [CpG ODN 1826 results in increased expression of PLIN3 protein] CTD PMID:20628022 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Chloroquine inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] CTD PMID:2993719 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO Chloroquine analog binds to and results in decreased activity of PPT1 protein; Chloroquine binds to and results in decreased activity of PPT1 protein CTD PMID:30442709 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prlr prolactin receptor decreases expression EXP Chloroquine results in decreased expression of PRLR mRNA CTD PMID:19393257 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Chloroquine results in increased expression of PTEN mRNA CTD PMID:31310755 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Chloroquine inhibits the reaction [resveratrol inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]] CTD PMID:24145604 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region increases expression ISO Chloroquine results in increased expression of RBPJ protein CTD PMID:22302987 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
increases activity
ISO
EXP
Acetylcysteine inhibits the reaction [Chloroquine results in increased activity of RELA protein]; diphenyliodonium inhibits the reaction [Chloroquine results in increased activity of RELA protein]
Chloroquine inhibits the reaction [[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of RELA protein]
Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of and affects the localization of RELA protein]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of RELA protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of and affects the localization of RELA protein]]
Chloroquine results in decreased expression of RELA protein
CTD PMID:15139008, PMID:24990399, PMID:26116531, PMID:28134560 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rheb Ras homolog, mTORC1 binding multiple interactions EXP Chloroquine inhibits the reaction [EGF protein results in increased expression of RHEB protein] CTD PMID:22689575 NCBI chr 4:6,827,429...6,873,384
Ensembl chr 4:6,827,429...6,873,383
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
increases expression
ISO
EXP
Chloroquine results in decreased phosphorylation of RPS6KB1 protein
Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]
Chloroquine results in increased expression of RPS6KB1 protein modified form
CTD PMID:22689575, PMID:25884947, PMID:31310755 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Chloroquine inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression
multiple interactions
EXP
ISO
Chloroquine results in decreased expression of SCARB1 mRNA
[Chloroquine co-treated with Lovastatin] inhibits the reaction [SCARB1 protein results in increased abundance of Progesterone]
CTD PMID:19393257, PMID:20404351 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression EXP Chloroquine results in decreased expression of SCCPDH mRNA CTD PMID:19393257 NCBI chr13:97,941,720...97,963,474
Ensembl chr13:97,941,757...97,963,824
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Chloroquine results in decreased expression of SCD1 mRNA CTD PMID:19393257 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Senp6 SUMO specific peptidase 6 multiple interactions ISO [Lipopolysaccharides co-treated with Chloroquine] results in increased expression of SENP6 protein CTD PMID:26807181 NCBI chr 8:87,486,050...87,568,088
Ensembl chr 8:87,486,427...87,563,652
JBrowse link
G Serpina3m serpin family A member 3M affects localization EXP Chloroquine affects the localization of SERPINA3 protein CTD PMID:8616629 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein] CTD PMID:30341573 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression ISO Chloroquine results in decreased expression of SLC12A1 protein CTD PMID:22791344 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc14a2 solute carrier family 14 member 2 multiple interactions ISO Chloroquine inhibits the reaction [AVP protein affects the localization of SLC14A2 protein] CTD PMID:22791344 NCBI chr18:74,508,070...74,941,389
Ensembl chr18:74,546,220...74,688,551
Ensembl chr18:74,546,220...74,688,551
JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Chloroquine inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Chloroquine inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:88,762,775...88,828,553
Ensembl chr 9:88,764,073...88,816,898
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Chloroquine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chloroquine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc2a4 solute carrier family 2 member 4 affects localization
multiple interactions
EXP Chloroquine affects the localization of SLC2A4 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Chloroquine affects the localization of SLC2A4 protein] which results in increased uptake of Glucose]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Chloroquine affects the localization of SLC2A4 protein]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Chloroquine affects the localization of SLC2A4 protein]; [[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein; gallein inhibits the reaction [Chloroquine affects the localization of SLC2A4 protein]
CTD PMID:27160165 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions ISO Chloroquine inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate] CTD PMID:27504015 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions EXP Chloroquine inhibits the reaction [Dibutyl Phthalate results in increased expression of SNAI1 mRNA] CTD PMID:30053495 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
ISO Quercetin inhibits the reaction [Chloroquine results in decreased expression of SOD1 mRNA] CTD PMID:23607047 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sort1 sortilin 1 decreases expression
multiple interactions
ISO Chloroquine results in decreased expression of SORT1 protein
Chloroquine affects the reaction [SORT1 protein affects the reaction [LDLR protein affects the abundance of Cholesterol]]
CTD PMID:25805502, PMID:30950489 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO
EXP
Chloroquine inhibits the reaction [[Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [ANGPTL8 protein results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Artesunate results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Cisplatin results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [cryptotanshinone results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein]; Chloroquine inhibits the reaction [formosanin C results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [fosbretabulin results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; Chloroquine inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [YM 155 results in decreased expression of SQSTM1 protein]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased expression of SQSTM1 protein]; Chloroquine promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; ERGIC3 protein promotes the reaction [Chloroquine results in increased expression of SQSTM1 protein]
Chloroquine inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [Cadmium results in decreased expression of SQSTM1 protein]; Chloroquine promotes the reaction [Glucose results in increased expression of SQSTM1 protein]; Chloroquine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein]; Chloroquine promotes the reaction [Resveratrol promotes the reaction [Glucose results in increased expression of SQSTM1 protein]]
Chloroquine inhibits the reaction [sunitinib results in decreased expression of SQSTM1 protein]
CTD PMID:21858812, PMID:22927544, PMID:23651616, PMID:24262987, PMID:24751611, PMID:25412314, PMID:25884947, PMID:25943029, PMID:27180204, PMID:27588471, PMID:27658547, PMID:28275691, PMID:28600121, PMID:28713934, PMID:28906492, PMID:29222055, PMID:29248574, PMID:29870746, PMID:30208301, PMID:30237538, PMID:30280407, PMID:30338810, PMID:30550853, PMID:30551460, PMID:31586597, PMID:31837377, PMID:32186374, PMID:32693121 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Ssb small RNA binding exonuclease protection factor La multiple interactions ISO Chloroquine inhibits the reaction [SSB protein results in increased expression of CXCL8 mRNA]; Chloroquine inhibits the reaction [SSB protein results in increased secretion of CXCL8 protein] CTD PMID:25915936 NCBI chr 3:56,092,425...56,102,008
Ensembl chr 3:56,092,501...56,102,001
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Chloroquine results in decreased expression of STAR mRNA CTD PMID:19393257 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stc2 stanniocalcin 2 decreases expression EXP Chloroquine results in decreased expression of STC2 mRNA CTD PMID:19393257 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression EXP Chloroquine results in decreased expression of STRAP mRNA CTD PMID:19393257 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link
G Syp synaptophysin multiple interactions EXP Chloroquine inhibits the reaction [Nanotubes, Carbon results in decreased expression of SYP] CTD PMID:26327526 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tardbp TAR DNA binding protein increases expression
multiple interactions
ISO Chloroquine results in increased expression of TARDBP protein
Chloroquine promotes the reaction [VCP protein mutant form results in increased expression of TARDBP protein]
CTD PMID:25884947 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tgoln2 trans-golgi network protein 2 affects localization ISO Chloroquine affects the localization of TGOLN2 protein CTD PMID:29940786 NCBI chr 4:100,475,415...100,483,229
Ensembl chr 4:100,475,416...100,483,168
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Chloroquine inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein] CTD PMID:24262987 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TICAM2 mRNA] CTD PMID:22341560 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
decreases expression
ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP1 protein]
Chloroquine results in decreased expression of TIMP1 mRNA
Chloroquine inhibits the reaction [Artesunate results in increased expression of TIMP1 mRNA]
CTD PMID:22341560, PMID:30551460 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP2 protein] CTD PMID:22341560 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO Chloroquine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein] CTD PMID:21398612 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Chloroquine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of TLR4 protein] CTD PMID:22341560 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr7 toll-like receptor 7 decreases activity ISO Chloroquine results in decreased activity of TLR7 protein CTD PMID:27385120 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tlr8 toll-like receptor 8 decreases activity ISO Chloroquine results in decreased activity of TLR8 protein CTD PMID:27385120 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tlr9 toll-like receptor 9 decreases activity
decreases expression
multiple interactions
increases expression
ISO
EXP
Chloroquine results in decreased activity of TLR9 protein
Chloroquine results in decreased expression of TLR9 protein
Chloroquine inhibits the reaction [[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of TLR9 protein]
Chloroquine results in increased expression of TLR9 mRNA
Chloroquine inhibits the reaction [CpG ODN 2006 results in increased activity of TLR9 protein]; Chloroquine inhibits the reaction [CpG ODN 2395 results in increased activity of TLR9 protein]; Chloroquine inhibits the reaction [Oxygen deficiency results in increased expression of TLR9 mRNA]; Oxygen deficiency inhibits the reaction [Chloroquine results in increased expression of TLR9 mRNA]; TLR9 protein promotes the reaction [Oxygen deficiency promotes the reaction [Chloroquine results in increased expression of MMP13 mRNA]]
CTD PMID:21398612, PMID:22595112, PMID:24273604, PMID:24990399 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression EXP Chloroquine results in decreased expression of TM7SF2 mRNA CTD PMID:19393257 NCBI chr 1:221,426,017...221,430,340
Ensembl chr 1:221,425,987...221,431,713
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
decreases secretion
increases expression
ISO
EXP
Chloroquine results in decreased expression of TNF protein
Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
[Chloroquine co-treated with TNF protein] results in increased expression of MAP1LC3B protein alternative form; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; Chloroquine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; Chloroquine promotes the reaction [[TNF protein co-treated with Resveratrol] results in increased expression of MAP1LC3B protein alternative form]
Chloroquine results in decreased secretion of TNF protein
Chloroquine results in increased expression of TNF
Chloroquine inhibits the reaction [CPG-oligonucleotide results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TNF protein]]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TNF mRNA]; Chloroquine promotes the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TNF protein]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]]
CTD PMID:8244452, PMID:9002011, PMID:9799232, PMID:10638776, PMID:15139008, PMID:22341560, PMID:24145604, PMID:26498332, PMID:28134560, PMID:31332898, PMID:31676321 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Chloroquine results in increased expression of TNFRSF10A protein CTD PMID:27692344 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNFRSF1A protein] CTD PMID:22341560 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNFRSF1B protein] CTD PMID:22341560 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 multiple interactions ISO Chloroquine promotes the reaction [Triiodothyronine results in increased expression of TOMM20 protein] CTD PMID:30209975 NCBI chr19:59,863,421...59,873,411
Ensembl chr19:59,863,421...59,873,411
JBrowse link
G Tp53 tumor protein p53 increases activity
multiple interactions
ISO Chloroquine results in increased activity of TP53; Chloroquine results in increased activity of TP53 protein
Chloroquine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]
TRP53 mutant form inhibits the reaction [Chloroquine results in increased activity of CASP3 protein]
CTD PMID:11589424, PMID:12082016, PMID:18089834, PMID:22927544 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions
ISO Chloroquine results in increased expression of TRIB3 protein
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; [Bortezomib co-treated with Chloroquine] results in increased expression of TRIB3 protein; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; Doxorubicin promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of TRIB3 protein]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of TRIB3 protein]; Nitroprusside promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; Nitroprusside promotes the reaction [Chloroquine results in increased expression of TRIB3 protein]
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of TRIB3 protein]; 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [Chloroquine results in increased expression of TRIB3 protein]; [Bortezomib co-treated with Chloroquine] results in increased expression of TRIB3 protein; betulinic acid inhibits the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; Doxorubicin promotes the reaction [[Bortezomib co-treated with Chloroquine] results in increased expression of TRIB3 protein]; Doxorubicin promotes the reaction [Chloroquine results in increased expression of TRIB3 protein]; Nitroprusside promotes the reaction [[Chloroquine co-treated with Bortezomib] results in increased expression of TRIB3 protein]; Nitroprusside promotes the reaction [Chloroquine results in increased expression of TRIB3 protein]
CTD PMID:30482226 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim63 tripartite motif containing 63 affects expression EXP Chloroquine affects the expression of TRIM63 mRNA CTD PMID:19296457 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179
JBrowse link
G Ubc ubiquitin C increases expression EXP Chloroquine results in increased expression of UBC mRNA CTD PMID:19296457 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
G Usp2 ubiquitin specific peptidase 2 multiple interactions
increases expression
ISO Chloroquine promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of USP2 mRNA]; lipopolysaccharide, E coli O55-B5 promotes the reaction [Chloroquine results in increased expression of USP2 mRNA] CTD PMID:28134560 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Usp25 ubiquitin specific peptidase 25 increases expression
multiple interactions
ISO Chloroquine results in increased expression of USP25 mRNA; Chloroquine results in increased expression of USP25 protein
[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of USP25 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Chloroquine] results in increased expression of USP25 protein; Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of USP25 mRNA]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [Chloroquine results in increased expression of USP25 mRNA]; USP25 protein affects the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of USP25 mRNA]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of IRF3 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of and affects the localization of RELA protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]]; USP25 protein affects the reaction [Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]]
CTD PMID:28134560 NCBI chr11:15,436,080...15,558,646
Ensembl chr11:15,436,269...15,558,646
JBrowse link
G Usp28 ubiquitin specific peptidase 28 multiple interactions
increases expression
ISO Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of USP28 mRNA]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [Chloroquine results in increased expression of USP28 mRNA] CTD PMID:28134560 NCBI chr 8:53,295,188...53,355,572
Ensembl chr 8:53,295,222...53,355,572
JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression
multiple interactions
ISO Chloroquine results in increased expression of USP7 mRNA
Chloroquine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of USP7 mRNA]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [Chloroquine results in increased expression of USP7 mRNA]
CTD PMID:28134560 NCBI chr10:6,930,462...7,019,910
Ensembl chr10:6,975,244...7,018,930
JBrowse link
G Vcp valosin-containing protein multiple interactions ISO Chloroquine inhibits the reaction [VCP protein mutant form results in decreased expression of MAP1LC3B protein]; Chloroquine inhibits the reaction [VCP protein mutant form results in increased expression of OPTN protein]
Chloroquine promotes the reaction [VCP protein mutant form results in increased expression of TARDBP protein]
CTD PMID:25884947 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Chloroquine results in decreased expression of VSNL1 mRNA CTD PMID:19393257 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 multiple interactions ISO Chloroquine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of XCL1 protein] CTD PMID:22341560 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
ciprofloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Ciprofloxacin results in decreased expression of ABCC2 mRNA CTD PMID:24657338 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Ciprofloxacin results in increased expression of ABCC3 mRNA CTD PMID:24657338 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases export
multiple interactions
increases expression
ISO ABCC4 protein results in increased export of Ciprofloxacin
[Ciprofloxacin results in increased expression of ABCC4 protein] which results in decreased uptake of Ciprofloxacin
Ciprofloxacin results in increased expression of ABCC4 mRNA; Ciprofloxacin results in increased expression of ABCC4 protein
[Ciprofloxacin results in increased expression of ABCC4 protein] which results in decreased uptake of Ciprofloxacin; Gemfibrozil inhibits the reaction [[Ciprofloxacin results in increased expression of ABCC4 protein] which results in decreased uptake of Ciprofloxacin]
CTD PMID:19307362, PMID:22162766 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Ciprofloxacin results in increased expression of ABCG2 protein CTD PMID:26947806 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Ciprofloxacin results in increased phosphorylation of AKT1 protein CTD PMID:26947806 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Ciprofloxacin results in increased expression of ALDH1A1 protein CTD PMID:26947806 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases localization
increases expression
ISO BCL2 protein inhibits the reaction [Ciprofloxacin results in increased localization of BAX protein]
Ciprofloxacin results in increased expression of BAX protein
CTD PMID:10741713, PMID:11832715, PMID:11875713, PMID:12632069 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Ciprofloxacin results in increased localization of BAX protein] CTD PMID:11832715, PMID:12063570 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Ciprofloxacin results in increased cleavage of and results in increased activity of CASP3 protein
Ciprofloxacin results in increased activity of CASP3 protein
CTD PMID:10741713, PMID:11832715, PMID:11875713, PMID:12632069 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO Ciprofloxacin results in increased activity of CASP8 protein CTD PMID:11875713 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO Ciprofloxacin results in increased activity of CASP9 protein CTD PMID:11875713 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cav1 caveolin 1 increases expression ISO Ciprofloxacin results in increased expression of CAV1 protein CTD PMID:26947806 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
ISO
EXP
Ciprofloxacin results in decreased expression of CCNB1 protein
Ciprofloxacin results in increased expression of CCNB1 mRNA; Ciprofloxacin results in increased expression of CCNB1 protein
CTD PMID:10741713, PMID:18512786 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Ciprofloxacin results in decreased expression of CCNE1 protein CTD PMID:10741713 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Ciprofloxacin results in increased expression of CD44 protein CTD PMID:26947806 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Ciprofloxacin results in increased expression of CDK1 mRNA; Ciprofloxacin results in increased expression of CDK1 protein CTD PMID:18512786 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases phosphorylation ISO Ciprofloxacin results in decreased phosphorylation of CDK2 protein CTD PMID:10741713 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Ciprofloxacin results in decreased expression of CDKN1A; Ciprofloxacin results in decreased expression of CDKN1A protein CTD PMID:10741713, PMID:12063570, PMID:12632069 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased activity of CEBPD mRNA] CTD PMID:11052920 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Chek1 checkpoint kinase 1 increases expression EXP Ciprofloxacin results in increased expression of CHEK1 protein CTD PMID:18512786 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Ciprofloxacin results in increased expression of CSF2 protein CTD PMID:11125792 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO Ciprofloxacin results in decreased expression of CXCL2 protein CTD PMID:18197910 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO [Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine; [Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of norclozapine; Ciprofloxacin inhibits the reaction [CYP1A2 protein affects the metabolism of tizanidine]; Ciprofloxacin inhibits the reaction [CYP1A2 protein results in decreased methylation of Caffeine] CTD PMID:11145498, PMID:11151749, PMID:15592331, PMID:18816299 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Ciprofloxacin results in decreased expression of CYP2C11 mRNA CTD PMID:12621481 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Ciprofloxacin results in decreased expression of CYP3A23-3A1 mRNA CTD PMID:12621481 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) multiple interactions
decreases activity
EXP Ciprofloxacin inhibits the reaction [DHODH protein results in increased oxidation of 4,5-dihydroorotic acid]
Ciprofloxacin results in decreased activity of DHODH protein
CTD PMID:9776318 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO Ciprofloxacin results in decreased expression of FGF15 mRNA CTD PMID:24657338 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases response to substance ISO G6PD protein mutant form results in increased susceptibility to Ciprofloxacin CTD PMID:20127091 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein; Buthionine Sulfoximine promotes the reaction [[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein] CTD PMID:29679711 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
ISO
EXP
Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]
[Ciprofloxacin co-treated with Cyclosporine] results in increased expression of IFNG mRNA; Ciprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of IFNG protein]]
Ciprofloxacin results in decreased expression of IFNG protein
CTD PMID:16006447, PMID:16968468, PMID:18337667, PMID:19401694 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
Ciprofloxacin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Ciprofloxacin inhibits the reaction [irinotecan inhibits the reaction [Mitogens results in increased expression of IL10 protein]]
CTD PMID:16939481, PMID:19401694 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] CTD PMID:16968468 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
Ciprofloxacin affects the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased activity of CEBPD mRNA]; Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]; Ciprofloxacin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Ciprofloxacin inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Ciprofloxacin promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; Ciprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Ciprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Ciprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein]; Ciprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP3 protein]
Ciprofloxacin inhibits the reaction [irinotecan inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]
Ciprofloxacin results in decreased expression of IL1B protein
CTD PMID:9267955, PMID:11052920, PMID:12428247, PMID:16148020, PMID:18197910, PMID:19401694 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions EXP Ciprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of IL2 protein]] CTD PMID:19401694 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 increases expression ISO Ciprofloxacin results in increased expression of IL3 mRNA; Ciprofloxacin results in increased expression of IL3 protein CTD PMID:11125792 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 decreases expression ISO Ciprofloxacin results in decreased expression of IL4 protein CTD PMID:16006447 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]
Ciprofloxacin inhibits the reaction [irinotecan inhibits the reaction [Mitogens results in increased expression of IL6 protein]]; Ciprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of IL6 protein]]
CTD PMID:9267955, PMID:11052920, PMID:19401694 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of LCN2 mRNA CTD PMID:29679711 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Ciprofloxacin results in increased phosphorylation of MAPK1 protein CTD PMID:26947806 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Ciprofloxacin results in increased phosphorylation of MAPK3 protein CTD PMID:26947806 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mb myoglobin multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased secretion of MB protein CTD PMID:29679711 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Ciprofloxacin results in increased expression of MCL1 protein CTD PMID:32437906 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR133B mRNA CTD PMID:29679711 NCBI chr 9:26,795,649...26,795,732
Ensembl chr 9:26,795,649...26,795,732
JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR206 mRNA CTD PMID:29679711 NCBI chr 9:26,791,764...26,791,847
Ensembl chr 9:26,791,764...26,791,847
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Ciprofloxacin results in decreased expression of MITF protein CTD PMID:32437906 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO Ciprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Ciprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein]
Ciprofloxacin results in increased expression of MMP1 mRNA
CTD PMID:12428247, PMID:16148020 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression
ISO Ciprofloxacin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Ciprofloxacin inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]
Ciprofloxacin results in decreased expression of MMP13 mRNA
CTD PMID:16148020 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO Ciprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Ciprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP3 protein]
Ciprofloxacin results in increased expression of MMP3 mRNA
CTD PMID:12428247 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:24101390 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nanog Nanog homeobox increases expression ISO Ciprofloxacin results in increased expression of NANOG protein CTD PMID:26947806 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 decreases response to substance ISO NOD2 gene SNP results in decreased susceptibility to Ciprofloxacin CTD PMID:18371140 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Ciprofloxacin results in increased expression of NR0B2 mRNA CTD PMID:24657338 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Ciprofloxacin results in increased cleavage of PARP1 protein CTD PMID:10741713 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Ciprofloxacin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Plk1 polo-like kinase 1 increases expression EXP Ciprofloxacin results in increased expression of PLK1 protein CTD PMID:18512786 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Ciprofloxacin results in decreased activity of PON1 protein CTD PMID:16880604, PMID:31581362 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO Ciprofloxacin results in increased expression of POU5F1 protein CTD PMID:26947806 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Prom1 prominin 1 increases expression ISO Ciprofloxacin results in increased expression of PROM1 protein CTD PMID:26947806 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects expression ISO Ciprofloxacin affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Ciprofloxacin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Slc2a1 solute carrier family 2 member 1 affects localization
decreases expression
ISO Ciprofloxacin affects the localization of SLC2A1 mRNA
Ciprofloxacin results in decreased expression of SLC2A1 mRNA
CTD PMID:19022360 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc51b solute carrier family 51 subunit beta decreases expression ISO Ciprofloxacin results in decreased expression of SLC51B mRNA CTD PMID:24657338 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression ISO Ciprofloxacin results in increased expression of SLCO1B2 mRNA CTD PMID:24657338 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO Ciprofloxacin results in decreased expression of SNAI1 protein CTD PMID:26947806 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO Ciprofloxacin results in decreased expression of SNAI2 protein CTD PMID:26947806 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Ciprofloxacin results in decreased expression of SOX2 protein CTD PMID:26947806 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO
EXP
Ciprofloxacin results in increased expression of TGFB1 mRNA
[Ciprofloxacin co-treated with Cyclosporine] results in decreased expression of TGFB1 mRNA
CTD PMID:18337667, PMID:19371339 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Ciprofloxacin affects the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased activity of CEBPD mRNA]; Ciprofloxacin inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]; Ciprofloxacin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Ciprofloxacin promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]
[Ciprofloxacin co-treated with Cyclosporine] results in decreased expression of TNF mRNA; [irinotecan co-treated with Ciprofloxacin] promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Ciprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of TNF protein]]
Ciprofloxacin results in decreased expression of TNF protein
CTD PMID:9267955, PMID:11052920, PMID:16939481, PMID:16968468, PMID:18197910, PMID:18337667, PMID:19401694 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top1 DNA topoisomerase I multiple interactions ISO [Ciprofloxacin co-treated with Camptothecin] results in decreased activity of TOP1 protein CTD PMID:18191106 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Top2a DNA topoisomerase II alpha affects binding
multiple interactions
ISO Ciprofloxacin binds to TOP2A protein
[Ciprofloxacin binds to TOP2A protein] inhibits the reaction [Etoposide binds to TOP2A protein]; [Ciprofloxacin binds to TOP2A protein] inhibits the reaction [F14512 binds to TOP2A protein]
CTD PMID:21413765 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of XIRP1 mRNA CTD PMID:29679711 NCBI chr 8:128,694,809...128,712,092
Ensembl chr 8:128,702,133...128,711,221
JBrowse link
glafenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Glafenine results in increased expression of A2M mRNA CTD PMID:24136188 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP Glafenine results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Aamdc adipogenesis associated, Mth938 domain containing decreases expression EXP Glafenine results in decreased expression of AAMDC mRNA CTD PMID:24136188 NCBI chr 1:162,519,513...162,549,211
Ensembl chr 1:162,519,521...162,533,893
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP Glafenine results in decreased expression of ABAT mRNA CTD PMID:24136188 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression EXP Glafenine results in increased expression of ABCA1 mRNA CTD PMID:24136188 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Glafenine results in decreased expression of ABCB11 mRNA CTD PMID:24136188 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression EXP Glafenine results in decreased expression of ABCB1 mRNA CTD PMID:24136188 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Glafenine results in decreased expression of ABCC2 mRNA CTD PMID:24136188 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression EXP Glafenine results in decreased expression of ABCD3 mRNA CTD PMID:24136188 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression EXP Glafenine results in decreased expression of ABCG5 mRNA CTD PMID:24136188 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression EXP Glafenine results in decreased expression of ABHD1 mRNA CTD PMID:24136188 NCBI chr 6:26,787,807...26,792,795
Ensembl chr 6:26,784,058...26,792,808
JBrowse link
G Abhd14b abhydrolase domain containing 14b decreases expression EXP Glafenine results in decreased expression of ABHD14B mRNA CTD PMID:24136188 NCBI chr 8:115,149,638...115,154,556
Ensembl chr 8:115,150,514...115,154,550
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Glafenine results in increased expression of ABHD2 mRNA CTD PMID:24136188 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase decreases expression EXP Glafenine results in decreased expression of ABHD6 mRNA CTD PMID:24136188 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Abi1 abl-interactor 1 decreases expression EXP Glafenine results in decreased expression of ABI1 mRNA CTD PMID:24136188 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328
JBrowse link
G Abraxas2 abraxas 2, BRISC complex subunit decreases expression EXP Glafenine results in decreased expression of ABRAXAS2 mRNA CTD PMID:24136188 NCBI chr 1:204,861,768...204,887,344
Ensembl chr 1:204,861,566...204,887,377
JBrowse link
G Abtb1 ankyrin repeat and BTB domain containing 1 decreases expression EXP Glafenine results in decreased expression of ABTB1 mRNA CTD PMID:24136188 NCBI chr 4:120,778,580...120,784,807
Ensembl chr 4:120,778,580...120,784,807
JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 decreases expression EXP Glafenine results in decreased expression of ABTB2 mRNA CTD PMID:24136188 NCBI chr 3:93,494,706...93,648,750
Ensembl chr 3:93,495,106...93,647,721
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression EXP Glafenine results in decreased expression of ACAA1 mRNA CTD PMID:24136188 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression EXP Glafenine results in increased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acad10 acyl-CoA dehydrogenase family, member 10 decreases expression EXP Glafenine results in decreased expression of ACAD10 mRNA CTD PMID:24136188 NCBI chr12:40,417,918...40,460,562
Ensembl chr12:40,417,944...40,460,561
JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 decreases expression EXP Glafenine results in decreased expression of ACAD11 mRNA CTD PMID:24136188 NCBI chr 8:112,594,758...112,676,275
Ensembl chr 8:112,594,691...112,676,280
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression EXP Glafenine results in decreased expression of ACAD9 mRNA CTD PMID:24136188 NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression EXP Glafenine results in decreased expression of ACADM mRNA CTD PMID:24136188 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acads acyl-CoA dehydrogenase short chain decreases expression EXP Glafenine results in decreased expression of ACADS mRNA CTD PMID:24136188 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 decreases expression EXP Glafenine results in decreased expression of ACBD5 mRNA CTD PMID:24136188 NCBI chr17:89,882,465...89,923,982
Ensembl chr17:89,883,615...89,923,423
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Glafenine results in increased expression of ACER2 mRNA CTD PMID:24136188 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression EXP Glafenine results in increased expression of ACKR3 mRNA CTD PMID:24136188 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Acot12 acyl-CoA thioesterase 12 decreases expression EXP Glafenine results in decreased expression of ACOT12 mRNA CTD PMID:24136188 NCBI chr 2:20,857,056...20,901,656
Ensembl chr 2:20,857,202...20,901,659
JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression EXP Glafenine results in decreased expression of ACOT2 mRNA CTD PMID:24136188 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot4 acyl-CoA thioesterase 4 decreases expression EXP Glafenine results in decreased expression of ACOT4 mRNA CTD PMID:24136188 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression EXP Glafenine results in decreased expression of ACOX1 mRNA CTD PMID:24136188 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP Glafenine results in decreased expression of ACSL1 mRNA CTD PMID:24136188 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression EXP Glafenine results in decreased expression of ACSM2A mRNA CTD PMID:24136188 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP Glafenine results in decreased expression of ACSS2 mRNA CTD PMID:24136188 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Actg1 actin, gamma 1 increases expression EXP Glafenine results in increased expression of ACTG1 mRNA CTD PMID:24136188 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression EXP Glafenine results in decreased expression of ADCK5 mRNA CTD PMID:24136188 NCBI chr 7:117,643,976...117,661,789
Ensembl chr 7:117,643,206...117,661,845
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression EXP Glafenine results in decreased expression of ADH4 mRNA CTD PMID:24136188 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP Glafenine results in decreased expression of ADHFE1 mRNA CTD PMID:24136188 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP Glafenine results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adk adenosine kinase decreases expression EXP Glafenine results in decreased expression of ADK mRNA CTD PMID:24136188 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adss adenylosuccinate synthase decreases expression EXP Glafenine results in decreased expression of ADSS mRNA CTD PMID:24136188 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761
JBrowse link
G Adssl1 adenylosuccinate synthase like 1 decreases expression EXP Glafenine results in decreased expression of ADSSL1 mRNA CTD PMID:24136188 NCBI chr 6:137,184,818...137,206,694
Ensembl chr 6:137,184,820...137,206,693
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein decreases expression EXP Glafenine results in decreased expression of ADTRP mRNA CTD PMID:24136188 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Afm afamin decreases expression EXP Glafenine results in decreased expression of AFM mRNA CTD PMID:24136188 NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
JBrowse link
G Afmid arylformamidase decreases expression EXP Glafenine results in decreased expression of AFMID mRNA CTD PMID:24136188 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Agmat agmatinase decreases expression EXP Glafenine results in decreased expression of AGMAT mRNA CTD PMID:24136188 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
G Agmo alkylglycerol monooxygenase decreases expression EXP Glafenine results in decreased expression of AGMO mRNA CTD PMID:24136188 NCBI chr 6:56,846,859...57,193,918
Ensembl chr 6:56,846,789...57,193,961
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression EXP Glafenine results in decreased expression of AHCY mRNA CTD PMID:24136188 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 increases expression EXP Glafenine results in increased expression of AIMP2 mRNA CTD PMID:24136188 NCBI chr12:12,738,784...12,748,345
Ensembl chr12:12,738,812...12,748,345
JBrowse link
G Ak3 adenylate kinase 3 decreases expression EXP Glafenine results in decreased expression of AK3 mRNA CTD PMID:24136188 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP Glafenine results in increased expression of AKR1A1 mRNA CTD PMID:24136188 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression EXP Glafenine results in decreased expression of AKR1C1 mRNA CTD PMID:24136188 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 decreases expression EXP Glafenine results in decreased expression of AKR1E2 mRNA CTD PMID:24136188 NCBI chr17:69,365,437...69,379,944
Ensembl chr17:69,365,453...69,379,947
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases expression EXP Glafenine results in decreased expression of AKR7A2 mRNA CTD PMID:24136188 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression EXP Glafenine results in decreased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression EXP Glafenine results in decreased expression of ALAS1 mRNA CTD PMID:24136188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Glafenine results in decreased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 decreases expression EXP Glafenine results in decreased expression of ALDH1L1 mRNA CTD PMID:24136188 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP Glafenine results in decreased expression of ALDH2 mRNA CTD PMID:24136188 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP Glafenine results in decreased expression of ALDH3A2 mRNA CTD PMID:24136188 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression EXP Glafenine results in decreased expression of ALDH4A1 mRNA CTD PMID:24136188 NCBI chr 5:158,090,238...158,115,725
Ensembl chr 5:158,042,587...158,135,733
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression EXP Glafenine results in decreased expression of ALDH5A1 mRNA CTD PMID:24136188 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression EXP Glafenine results in decreased expression of ALDH6A1 mRNA CTD PMID:24136188 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression EXP Glafenine results in decreased expression of ALDH9A1 mRNA CTD PMID:24136188 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Glafenine results in increased expression of ALDOA mRNA CTD PMID:24136188 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression EXP Glafenine results in increased expression of ALG12 mRNA CTD PMID:24136188 NCBI chr 7:129,798,663...129,812,677
Ensembl chr 7:129,798,663...129,812,388
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase increases expression EXP Glafenine results in increased expression of ALG2 mRNA CTD PMID:24136188 NCBI chr 5:63,187,466...63,192,025
Ensembl chr 5:63,187,468...63,192,025
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase increases expression EXP Glafenine results in increased expression of ALG3 mRNA CTD PMID:24136188 NCBI chr11:83,985,484...83,991,706
Ensembl chr11:83,986,230...83,991,706
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression EXP Glafenine results in decreased expression of AMACR mRNA CTD PMID:24136188 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression EXP Glafenine results in increased expression of AMIGO3 mRNA CTD PMID:24136188 NCBI chr 8:116,830,773...116,832,299 JBrowse link
G Amy1a amylase, alpha 1A decreases expression EXP Glafenine results in decreased expression of AMY1A mRNA CTD PMID:24136188 NCBI chr 2:216,428,709...216,443,518
Ensembl chr 2:216,428,709...216,443,518
JBrowse link
G Ang angiogenin decreases expression EXP Glafenine results in decreased expression of ANG mRNA CTD PMID:24136188 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP Glafenine results in decreased expression of ANGPTL3 mRNA CTD PMID:24136188 NCBI chr 5:117,698,590...117,706,729
Ensembl chr 5:117,698,764...117,705,808
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP Glafenine results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:10,917,359...10,937,522
Ensembl chr 7:10,917,367...10,936,415
JBrowse link
G Ankrd46 ankyrin repeat domain 46 decreases expression EXP Glafenine results in decreased expression of ANKRD46 mRNA CTD PMID:24136188 NCBI chr 7:75,279,443...75,300,442
Ensembl chr 7:75,279,446...75,288,365
JBrowse link
G Anks4b ankyrin repeat and sterile alpha motif domain containing 4B decreases expression EXP Glafenine results in decreased expression of ANKS4B mRNA CTD PMID:24136188 NCBI chr 1:189,940,305...189,942,113
Ensembl chr 1:189,940,291...189,942,112
JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 decreases expression EXP Glafenine results in decreased expression of ANTXR2 mRNA CTD PMID:24136188 NCBI chr14:13,191,716...13,331,286
Ensembl chr14:13,192,347...13,274,978
JBrowse link
G Anxa4 annexin A4 decreases expression EXP Glafenine results in decreased expression of ANXA4 mRNA CTD PMID:24136188 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Apeg3 antisense paternally expressed gene 3 increases expression EXP Glafenine results in increased expression of APEG3 mRNA CTD PMID:24136188 NCBI chr 1:70,234,160...70,235,091
Ensembl chr 1:70,234,160...70,235,091
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Glafenine results in increased expression of APEX1 mRNA CTD PMID:24136188 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP Glafenine results in decreased expression of APMAP mRNA CTD PMID:24136188 NCBI chr 3:146,376,828...146,407,259
Ensembl chr 3:146,376,828...146,407,252
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP Glafenine results in decreased expression of APOA2 mRNA CTD PMID:24136188 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 decreases expression EXP Glafenine results in decreased expression of APPBP2 mRNA CTD PMID:24136188 NCBI chr10:72,503,347...72,545,141
Ensembl chr10:72,503,347...72,545,141
JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP Glafenine results in increased expression of APRT mRNA CTD PMID:24136188 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Arf4 ADP-ribosylation factor 4 increases expression EXP Glafenine results in increased expression of ARF4 mRNA CTD PMID:24136188 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Arfgap3 ADP-ribosylation factor GTPase activating protein 3 increases expression EXP Glafenine results in increased expression of ARFGAP3 mRNA CTD PMID:24136188 NCBI chr 7:124,149,665...124,198,298
Ensembl chr 7:124,149,751...124,198,200
JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 decreases expression EXP Glafenine results in decreased expression of ARFGEF1 mRNA CTD PMID:24136188 NCBI chr 5:8,666,046...8,760,458
Ensembl chr 5:8,666,200...8,760,458
JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 increases expression EXP Glafenine results in increased expression of ARFIP2 mRNA CTD PMID:24136188 NCBI chr 1:170,464,995...170,471,138
Ensembl chr 1:170,466,395...170,471,076
JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Glafenine results in increased expression of ARHGAP1 mRNA CTD PMID:24136188 NCBI chr 3:80,555,196...80,576,881
Ensembl chr 3:80,555,196...80,576,856
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression EXP Glafenine results in decreased expression of ARHGAP18 mRNA CTD PMID:24136188 NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP Glafenine results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 decreases expression EXP Glafenine results in decreased expression of ARL6IP1 mRNA CTD PMID:24136188 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 increases expression EXP Glafenine results in increased expression of ARL6IP4 mRNA CTD PMID:24136188 NCBI chr12:37,904,376...37,906,521
Ensembl chr12:37,904,379...37,906,521
JBrowse link
G Armc9 armadillo repeat containing 9 increases expression EXP Glafenine results in increased expression of ARMC9 mRNA CTD PMID:24136188 NCBI chr 9:93,172,718...93,299,119
Ensembl chr 9:93,172,673...93,296,750
JBrowse link
G Armcx3 armadillo repeat containing, X-linked 3 increases expression EXP Glafenine results in increased expression of ARMCX3 mRNA CTD PMID:24136188 NCBI chr  X:105,573,909...105,577,480
Ensembl chr  X:105,573,909...105,580,562
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP Glafenine results in increased expression of ARPC1B mRNA CTD PMID:24136188 NCBI chr12:11,252,300...11,265,849
Ensembl chr12:11,252,296...11,265,865
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP Glafenine results in increased expression of ARPC5L mRNA CTD PMID:24136188 NCBI chr 3:23,301,455...23,309,077
Ensembl chr 3:23,301,455...23,309,072
JBrowse link
G Asl argininosuccinate lyase decreases expression EXP Glafenine results in decreased expression of ASL mRNA CTD PMID:24136188 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP Glafenine results in decreased expression of ASS1 mRNA CTD PMID:24136188 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP Glafenine results in increased expression of ATF4 mRNA CTD PMID:24136188 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg13 autophagy related 13 increases expression EXP Glafenine results in increased expression of ATG13 mRNA CTD PMID:24136188 NCBI chr 3:80,580,549...80,614,554
Ensembl chr 3:80,581,247...80,601,410
JBrowse link
G Atg16l2 autophagy related 16-like 2 increases expression EXP Glafenine results in increased expression of ATG16L2 mRNA CTD PMID:24136188 NCBI chr 1:166,401,271...166,415,078
Ensembl chr 1:166,401,271...166,413,564
JBrowse link
G Atg2b autophagy related 2B decreases expression EXP Glafenine results in decreased expression of ATG2B mRNA CTD PMID:24136188 NCBI chr 6:129,449,451...129,519,599
Ensembl chr 6:129,449,449...129,509,720
JBrowse link
G Atl2 atlastin GTPase 2 decreases expression EXP Glafenine results in decreased expression of ATL2 mRNA CTD PMID:24136188 NCBI chr 6:2,568,975...2,610,432
Ensembl chr 6:2,568,990...2,610,437
JBrowse link
G Atp11a ATPase phospholipid transporting 11A decreases expression EXP Glafenine results in decreased expression of ATP11A mRNA CTD PMID:24136188 NCBI chr16:81,990,340...82,100,222
Ensembl chr16:81,990,340...82,100,222
JBrowse link
G Atp11c ATPase phospholipid transporting 11C decreases expression EXP Glafenine results in decreased expression of ATP11C mRNA CTD PMID:24136188 NCBI chr  X:143,340,712...143,525,588
Ensembl chr  X:143,346,252...143,453,612
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Glafenine results in decreased expression of ATP1B1 mRNA CTD PMID:24136188 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression EXP Glafenine results in increased expression of ATP2A2 mRNA CTD PMID:24136188 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP Glafenine results in increased expression of ATP5MC1 mRNA CTD PMID:24136188 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527
JBrowse link
G Atrn attractin decreases expression EXP Glafenine results in decreased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:123,434,409...123,567,922
Ensembl chr 3:123,434,409...123,567,918
JBrowse link
G Atxn2 ataxin 2 decreases expression EXP Glafenine results in decreased expression of ATXN2 mRNA CTD PMID:24136188 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 increases expression EXP Glafenine results in increased expression of AURKAIP1 mRNA CTD PMID:24136188 NCBI chr 5:173,274,433...173,276,170
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G B2m beta-2 microglobulin decreases expression EXP Glafenine results in decreased expression of B2M mRNA CTD PMID:24136188 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression EXP Glafenine results in increased expression of B4GALT1 mRNA CTD PMID:24136188 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G B4gat1 beta-1,4-glucuronyltransferase 1 decreases expression EXP Glafenine results in decreased expression of B4GAT1 mRNA CTD PMID:24136188 NCBI chr 1:220,322,854...220,325,076
Ensembl chr 1:220,416,018...220,418,240
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression EXP Glafenine results in decreased expression of BAAT mRNA CTD PMID:24136188 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 increases expression EXP Glafenine results in increased expression of BABAM1 mRNA CTD PMID:24136188 NCBI chr16:19,792,720...19,798,886
Ensembl chr16:19,792,838...19,798,894
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Glafenine results in increased expression of BASP1 mRNA CTD PMID:24136188 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP Glafenine results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 decreases expression EXP Glafenine results in decreased expression of BBS2 mRNA CTD PMID:24136188 NCBI chr19:11,385,921...11,421,523
Ensembl chr19:11,386,024...11,421,498
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression EXP Glafenine results in increased expression of BCL3 mRNA CTD PMID:24136188 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like increases expression EXP Glafenine results in increased expression of BET1L mRNA CTD PMID:24136188 NCBI chr 1:213,602,836...213,606,507
Ensembl chr 1:213,602,850...213,605,643
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP Glafenine results in increased expression of BHLHE40 mRNA CTD PMID:24136188 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP Glafenine results in decreased expression of BHMT mRNA CTD PMID:24136188 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 decreases expression EXP Glafenine results in decreased expression of BHMT2 mRNA CTD PMID:24136188 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 decreases expression EXP Glafenine results in decreased expression of BLOC1S5 mRNA CTD PMID:24136188 NCBI chr17:26,808,193...26,833,257
Ensembl chr17:26,808,330...26,833,247
JBrowse link
G Blvrb biliverdin reductase B decreases expression EXP Glafenine results in decreased expression of BLVRB mRNA CTD PMID:24136188 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression EXP Glafenine results in increased expression of BNIP1 mRNA CTD PMID:24136188 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression EXP Glafenine results in decreased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bola3 bolA family member 3 increases expression EXP Glafenine results in increased expression of BOLA3 mRNA CTD PMID:24136188 NCBI chr 4:115,046,693...115,056,140
Ensembl chr 4:115,046,693...115,056,140
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression EXP Glafenine results in increased expression of BOP1 mRNA CTD PMID:24136188 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G Borcs7 BLOC-1 related complex subunit 7 increases expression EXP Glafenine results in increased expression of BORCS7 mRNA CTD PMID:24136188 NCBI chr 1:266,451,021...266,464,903
Ensembl chr 1:266,451,021...266,464,903
JBrowse link
G Bphl biphenyl hydrolase like decreases expression EXP Glafenine results in decreased expression of BPHL mRNA CTD PMID:24136188 NCBI chr17:31,498,877...31,535,172
Ensembl chr17:31,498,883...31,535,172
JBrowse link
G Brd3 bromodomain containing 3 decreases expression EXP Glafenine results in decreased expression of BRD3 mRNA CTD PMID:24136188 NCBI chr 3:5,995,204...6,054,467
Ensembl chr 3:5,997,315...6,054,483
JBrowse link
G Brix1 biogenesis of ribosomes BRX1 increases expression EXP Glafenine results in increased expression of BRIX1 mRNA CTD PMID:24136188 NCBI chr 2:60,450,547...60,461,425
Ensembl chr 2:60,450,374...60,461,458
JBrowse link
G Btbd1 BTB domain containing 1 decreases expression EXP Glafenine results in decreased expression of BTBD1 mRNA CTD PMID:24136188 NCBI chr 1:143,609,729...143,647,124
Ensembl chr 1:143,609,731...143,647,124
JBrowse link
G Btbd11 BTB domain containing 11 decreases expression EXP Glafenine results in decreased expression of BTBD11 mRNA CTD PMID:24136188 NCBI chr 7:24,041,194...24,314,418
Ensembl chr 7:24,043,126...24,313,885
JBrowse link
G Btbd6 BTB domain containing 6 decreases expression EXP Glafenine results in decreased expression of BTBD6 mRNA CTD PMID:24136188 NCBI chr 6:137,785,662...137,788,442
Ensembl chr 6:137,785,982...137,788,434
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Glafenine results in increased expression of BTG2 mRNA CTD PMID:24136188 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression EXP Glafenine results in increased expression of BTG3 mRNA CTD PMID:24136188 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Bysl bystin-like increases expression EXP Glafenine results in increased expression of BYSL mRNA CTD PMID:24136188 NCBI chr 9:15,393,461...15,403,212
Ensembl chr 9:15,393,330...15,403,117
JBrowse link
G C1qbp complement C1q binding protein increases expression EXP Glafenine results in increased expression of C1QBP mRNA CTD PMID:24136188 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C4bpb complement component 4 binding protein, beta increases expression EXP Glafenine results in increased expression of C4BPB mRNA CTD PMID:24136188 NCBI chr13:47,387,173...47,398,115
Ensembl chr13:47,387,173...47,397,890
JBrowse link
G C5 complement C5 increases expression EXP Glafenine results in increased expression of C5 mRNA CTD PMID:24136188 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G C9 complement C9 increases expression EXP Glafenine results in increased expression of C9 mRNA CTD PMID:24136188 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression EXP Glafenine results in decreased expression of CAR14 mRNA CTD PMID:24136188 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP Glafenine results in decreased expression of CAR3 mRNA CTD PMID:24136188 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca5a carbonic anhydrase 5A decreases expression EXP Glafenine results in decreased expression of CAR5A mRNA CTD PMID:24136188 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca8 carbonic anhydrase 8 increases expression EXP Glafenine results in increased expression of CAR8 mRNA CTD PMID:24136188 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase increases expression EXP Glafenine results in increased expression of CAD mRNA CTD PMID:24136188 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Calm1 calmodulin 1 increases expression EXP Glafenine results in increased expression of CALM1 mRNA CTD PMID:24136188 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calr calreticulin increases expression EXP Glafenine results in increased expression of CALR mRNA CTD PMID:24136188 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin increases expression EXP Glafenine results in increased expression of CALU mRNA CTD PMID:24136188 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Caprin1 cell cycle associated protein 1 decreases expression EXP Glafenine results in decreased expression of CAPRIN1 mRNA CTD PMID:24136188 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression EXP Glafenine results in increased expression of CARS mRNA CTD PMID:24136188 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Cars2 cysteinyl-tRNA synthetase 2, mitochondrial decreases expression EXP Glafenine results in decreased expression of CARS2 mRNA CTD PMID:24136188 NCBI chr16:83,288,613...83,325,706
Ensembl chr16:83,288,664...83,325,699
JBrowse link
G Cat catalase decreases expression EXP Glafenine results in decreased expression of CAT mRNA CTD PMID:24136188 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav2 caveolin 2 increases expression EXP Glafenine results in increased expression of CAV2 mRNA CTD PMID:24136188 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Cbr4 carbonyl reductase 4 decreases expression EXP Glafenine results in decreased expression of CBR4 mRNA CTD PMID:24136188 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Ccdc125 coiled-coil domain containing 125 increases expression EXP Glafenine results in increased expression of CCDC125 mRNA CTD PMID:24136188 NCBI chr 2:30,685,845...30,726,617
Ensembl chr 2:30,685,840...30,704,487
JBrowse link
G Ccdc134 coiled-coil domain containing 134 increases expression EXP Glafenine results in increased expression of CCDC134 mRNA CTD PMID:24136188 NCBI chr 7:123,362,471...123,376,930
Ensembl chr 7:123,364,312...123,376,221
JBrowse link
G Ccdc167 coiled-coil domain containing 167 increases expression EXP Glafenine results in increased expression of CCDC167 mRNA CTD PMID:24136188 NCBI chr20:8,367,047...8,384,119
Ensembl chr20:8,369,331...8,384,088
JBrowse link
G Ccdc28a coiled-coil domain containing 28A decreases expression EXP Glafenine results in decreased expression of CCDC28A mRNA CTD PMID:24136188 NCBI chr 1:13,384,153...13,395,643
Ensembl chr 1:13,384,156...13,395,370
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression EXP Glafenine results in increased expression of CCDC86 mRNA CTD PMID:24136188 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccng2 cyclin G2 decreases expression EXP Glafenine results in decreased expression of CCNG2 mRNA CTD PMID:24136188 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccni cyclin I decreases expression EXP Glafenine results in decreased expression of CCNI mRNA CTD PMID:24136188 NCBI chr14:16,341,510...16,364,326
Ensembl chr14:16,341,536...16,364,326
JBrowse link
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 increases expression EXP Glafenine results in increased expression of CD2BP2 mRNA CTD PMID:24136188 NCBI chr 1:198,635,445...198,641,195
Ensembl chr 1:198,635,447...198,638,944
JBrowse link
G Cd48 Cd48 molecule increases expression EXP Glafenine results in increased expression of CD48 mRNA CTD PMID:24136188 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd59 CD59 molecule decreases expression EXP Glafenine results in decreased expression of CD59 mRNA CTD PMID:24136188 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 decreases expression EXP Glafenine results in decreased expression of CDADC1 mRNA CTD PMID:24136188 NCBI chr15:39,865,094...39,894,122
Ensembl chr15:39,882,210...39,893,979
JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression EXP Glafenine results in increased expression of CDC42SE1 mRNA CTD PMID:24136188 NCBI chr 2:196,402,837...196,410,664
Ensembl chr 2:196,402,837...196,410,659
JBrowse link
G Cdc5l cell division cycle 5-like decreases expression EXP Glafenine results in decreased expression of CDC5L mRNA CTD PMID:24136188 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Glafenine results in decreased expression of CDH2 mRNA CTD PMID:24136188 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdip1 cell death-inducing p53 target 1 decreases expression EXP Glafenine results in decreased expression of CDIP1 mRNA CTD PMID:24136188 NCBI chr10:10,966,819...10,989,937
Ensembl chr10:10,967,658...10,989,936
JBrowse link
G Cdk2ap1 cyclin-dependent kinase 2 associated protein 1 increases expression EXP Glafenine results in increased expression of CDK2AP1 mRNA CTD PMID:24136188 NCBI chr12:37,668,369...37,677,067
Ensembl chr12:37,668,369...37,677,063
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 increases expression EXP Glafenine results in increased expression of CDK2AP2 mRNA CTD PMID:24136188 NCBI chr 1:219,345,638...219,347,709
Ensembl chr 1:219,345,918...219,347,728
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Glafenine results in increased expression of CDK4 mRNA CTD PMID:24136188 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Glafenine results in increased expression of CDKN1A mRNA CTD PMID:24136188 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression EXP Glafenine results in decreased expression of CDKN1B mRNA CTD PMID:24136188 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Glafenine results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP Glafenine results in decreased expression of CDO1 mRNA CTD PMID:24136188 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression EXP Glafenine results in decreased expression of CEACAM1 mRNA CTD PMID:24136188 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP Glafenine results in increased expression of CEBPD mRNA CTD PMID:24136188 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 increases expression EXP Glafenine results in increased expression of CEMIP2 mRNA CTD PMID:24136188 NCBI chr 1:239,397,322...239,474,931
Ensembl chr 1:239,398,043...239,474,931
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 decreases expression EXP Glafenine results in decreased expression of CEPT1 mRNA CTD PMID:24136188 NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Glafenine results in decreased expression of CES1D mRNA CTD PMID:24136188 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression EXP Glafenine results in decreased expression of CHAC2 mRNA CTD PMID:24136188 NCBI chr14:115,383,906...115,391,757
Ensembl chr14:115,383,910...115,391,652
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP Glafenine results in increased expression of CHCHD6 mRNA CTD PMID:24136188 NCBI chr 4:121,340,952...121,565,222
Ensembl chr 4:121,340,952...121,565,212
JBrowse link
G Chid1 chitinase domain containing 1 increases expression EXP Glafenine results in increased expression of CHID1 mRNA CTD PMID:24136188 NCBI chr 1:214,476,418...214,511,569
Ensembl chr 1:214,476,387...214,511,529
JBrowse link
G Chmp4c charged multivesicular body protein 4C decreases expression EXP Glafenine results in decreased expression of CHMP4C mRNA CTD PMID:24136188 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 increases expression EXP Glafenine results in increased expression of CHPF2 mRNA CTD PMID:24136188 NCBI chr 4:7,108,461...7,113,940
Ensembl chr 4:7,108,462...7,113,919
JBrowse link
G Cic capicua transcriptional repressor increases expression EXP Glafenine results in increased expression of CIC mRNA CTD PMID:24136188 NCBI chr 1:82,135,440...82,163,007
Ensembl chr 1:82,151,669...82,163,005
JBrowse link
G Cinp cyclin-dependent kinase 2-interacting protein increases expression EXP Glafenine results in increased expression of CINP mRNA CTD PMID:24136188 NCBI chr 6:135,290,528...135,304,422
Ensembl chr 6:135,290,530...135,304,422
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Glafenine results in increased expression of CISD2 mRNA CTD PMID:24136188 NCBI chr 2:240,586,754...240,611,560
Ensembl chr 2:240,586,754...240,611,560
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression EXP Glafenine results in increased expression of CKS1B mRNA CTD PMID:24136188 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Clcn4 chloride voltage-gated channel 4 decreases expression EXP Glafenine results in decreased expression of CLCN4 mRNA CTD PMID:24136188 NCBI chr  X:25,016,177...25,082,563
Ensembl chr  X:25,016,401...25,080,410
JBrowse link
G Clic1 chloride intracellular channel 1 increases expression EXP Glafenine results in increased expression of CLIC1 mRNA CTD PMID:24136188 NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression EXP Glafenine results in decreased expression of CLPX mRNA CTD PMID:24136188 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog decreases expression EXP Glafenine results in decreased expression of CMBL mRNA CTD PMID:24136188 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Cmtr1 cap methyltransferase 1 decreases expression EXP Glafenine results in decreased expression of CMTR1 mRNA CTD PMID:24136188 NCBI chr20:8,324,968...8,385,174
Ensembl chr20:8,312,792...8,368,764
JBrowse link
G Cnn2 calponin 2 increases expression EXP Glafenine results in increased expression of CNN2 mRNA CTD PMID:24136188 NCBI chr 7:12,782,459...12,787,977
Ensembl chr 7:12,782,491...12,787,750
JBrowse link
G Cnppd1 cyclin Pas1/PHO80 domain containing 1 decreases expression EXP Glafenine results in decreased expression of CNPPD1 mRNA CTD PMID:24136188 NCBI chr 9:82,338,865...82,345,262
Ensembl chr 9:82,338,866...82,345,262
JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 increases expression EXP Glafenine results in increased expression of CNPY2 mRNA CTD PMID:24136188 NCBI chr 7:2,737,674...2,744,321
Ensembl chr 7:2,737,765...2,742,369
JBrowse link
G Cnpy3 canopy FGF signaling regulator 3 increases expression EXP Glafenine results in increased expression of CNPY3 mRNA CTD PMID:24136188 NCBI chr 9:16,543,715...16,558,441
Ensembl chr 9:16,543,688...16,558,456
JBrowse link
G Coasy Coenzyme A synthase decreases expression EXP Glafenine results in decreased expression of COASY mRNA CTD PMID:24136188 NCBI chr10:88,992,413...88,996,677
Ensembl chr10:88,992,487...88,996,676
JBrowse link
G Cog3 component of oligomeric golgi complex 3 increases expression EXP Glafenine results in increased expression of COG3 mRNA CTD PMID:24136188 NCBI chr15:57,753,814...57,805,627
Ensembl chr15:57,755,189...57,805,184
JBrowse link
G Cog4 component of oligomeric golgi complex 4 decreases expression EXP Glafenine results in decreased expression of COG4 mRNA CTD PMID:24136188 NCBI chr19:43,358,057...43,391,828
Ensembl chr19:43,358,057...43,391,828
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression EXP Glafenine results in increased expression of COL18A1 mRNA CTD PMID:24136188 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression EXP Glafenine results in increased expression of COL4A1 mRNA CTD PMID:24136188 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Copa COPI coat complex subunit alpha increases expression EXP Glafenine results in increased expression of COPA mRNA CTD PMID:24136188 NCBI chr13:90,467,285...90,508,894
Ensembl chr13:90,467,265...90,508,932
JBrowse link
G Cope COPI coat complex subunit epsilon increases expression EXP Glafenine results in increased expression of COPE mRNA CTD PMID:24136188 NCBI chr16:20,863,141...20,873,516
Ensembl chr16:20,863,141...20,873,521
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 increases expression EXP Glafenine results in increased expression of COPG1 mRNA CTD PMID:24136188 NCBI chr 4:119,815,041...119,840,997
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 decreases expression EXP Glafenine results in decreased expression of COPG2 mRNA CTD PMID:24136188 NCBI chr 4:58,064,394...58,195,242
Ensembl chr 4:58,064,833...58,195,143
JBrowse link
G Copz1 COPI coat complex subunit zeta 1 increases expression EXP Glafenine results in increased expression of COPZ1 mRNA CTD PMID:24136188 NCBI chr 7:144,900,050...144,926,299
Ensembl chr 7:144,899,534...144,926,350
JBrowse link
G Copz2 COPI coat complex subunit zeta 2 increases expression EXP Glafenine results in increased expression of COPZ2 mRNA CTD PMID:24136188 NCBI chr10:84,718,824...84,731,880
Ensembl chr10:84,718,824...84,731,880
JBrowse link
G Coq10a coenzyme Q10A decreases expression EXP Glafenine results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr 7:2,780,930...2,788,189
Ensembl chr 7:2,780,930...2,786,949
JBrowse link
G Coq10b coenzyme Q10B increases expression EXP Glafenine results in increased expression of COQ10B mRNA CTD PMID:24136188 NCBI chr 9:61,655,963...61,675,880
Ensembl chr 9:61,655,963...61,675,873
JBrowse link
G Coq8a coenzyme Q8A decreases expression EXP Glafenine results in decreased expression of COQ8A mRNA CTD PMID:24136188 NCBI chr13:98,451,629...98,480,438
Ensembl chr13:98,451,637...98,480,419
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 increases expression EXP Glafenine results in increased expression of COTL1 mRNA CTD PMID:24136188 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression EXP Glafenine results in decreased expression of COX5A mRNA CTD PMID:24136188 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression EXP Glafenine results in increased expression of COX5B mRNA CTD PMID:24136188 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cp ceruloplasmin increases expression EXP Glafenine results in increased expression of CP mRNA CTD PMID:24136188 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpne3 copine 3 decreases expression EXP Glafenine results in decreased expression of CPNE3 mRNA CTD PMID:24136188 NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
JBrowse link
G Cpne8 copine 8 increases expression EXP Glafenine results in increased expression of CPNE8 mRNA CTD PMID:24136188 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 decreases expression EXP Glafenine results in decreased expression of CPPED1 mRNA CTD PMID:24136188 NCBI chr10:3,655,038...3,774,887
Ensembl chr10:3,655,038...3,774,884
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP Glafenine results in decreased expression of PGCP mRNA CTD PMID:24136188 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP Glafenine results in decreased expression of CPS1 mRNA CTD PMID:24136188 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression EXP Glafenine results in decreased expression of CPT2 mRNA CTD PMID:24136188 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression EXP Glafenine results in decreased expression of CRAT mRNA CTD PMID:24136188 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crbn cereblon decreases expression EXP Glafenine results in decreased expression of CRBN mRNA CTD PMID:24136188 NCBI chr 4:138,864,910...138,885,786
Ensembl chr 4:138,866,761...138,885,556
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression EXP Glafenine results in decreased expression of CREB3L3 mRNA CTD PMID:24136188 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Crebzf CREB/ATF bZIP transcription factor decreases expression EXP Glafenine results in decreased expression of CREBZF mRNA CTD PMID:24136188 NCBI chr 1:156,290,215...156,296,891
Ensembl chr 1:156,294,519...156,296,161
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression EXP Glafenine results in increased expression of CRELD2 mRNA CTD PMID:24136188 NCBI chr 7:129,812,746...129,819,641
Ensembl chr 7:129,812,789...129,819,634
JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP Glafenine results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression EXP Glafenine results in decreased expression of CRLS1 mRNA CTD PMID:24136188 NCBI chr 3:125,503,638...125,522,460
Ensembl chr 3:125,503,638...125,522,441
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression EXP Glafenine results in decreased expression of CROT mRNA CTD PMID:24136188 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Crybg2 crystallin beta-gamma domain containing 2 decreases expression EXP Glafenine results in decreased expression of CRYBG2 mRNA CTD PMID:24136188 NCBI chr 5:152,289,492...152,321,539
Ensembl chr 5:152,290,084...152,321,541
JBrowse link
G Cryl1 crystallin, lambda 1 decreases expression EXP Glafenine results in decreased expression of CRYL1 mRNA CTD PMID:24136188 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Crym crystallin, mu decreases expression EXP Glafenine results in decreased expression of CRYM mRNA CTD PMID:24136188 NCBI chr 1:189,944,895...189,960,069
Ensembl chr 1:189,944,895...189,960,073
JBrowse link
G Cryz crystallin zeta decreases expression EXP Glafenine results in decreased expression of CRYZ mRNA CTD PMID:24136188 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP Glafenine results in increased expression of CSF1 mRNA CTD PMID:24136188 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Ctbs chitobiase decreases expression EXP Glafenine results in decreased expression of CTBS mRNA CTD PMID:24136188 NCBI chr 2:252,305,874...252,320,387
Ensembl chr 2:252,305,874...252,320,387
JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP Glafenine results in decreased expression of CTH mRNA CTD PMID:24136188 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression EXP Glafenine results in decreased expression of CTNNA1 mRNA CTD PMID:24136188 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctps1 CTP synthase 1 increases expression EXP Glafenine results in increased expression of CTPS1 mRNA CTD PMID:24136188 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctsa cathepsin A decreases expression EXP Glafenine results in decreased expression of CTSA mRNA CTD PMID:24136188 NCBI chr 3:161,298,750...161,304,627
Ensembl chr 3:161,298,962...161,304,625
JBrowse link
G Ctsf cathepsin F decreases expression EXP Glafenine results in decreased expression of CTSF mRNA CTD PMID:24136188 NCBI chr 1:220,114,228...220,119,976
Ensembl chr 1:220,114,228...220,119,976
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Glafenine results in increased expression of CXCL1 mRNA CTD PMID:24136188 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP Glafenine results in decreased expression of CXCL12 mRNA CTD PMID:24136188 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Glafenine results in decreased expression of CXCL9 mRNA CTD PMID:24136188 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP Glafenine results in decreased expression of CYB5R3 mRNA CTD PMID:24136188 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP17A1 mRNA CTD PMID:24136188 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP27A1 mRNA CTD PMID:24136188 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP2A1 mRNA CTD PMID:24136188 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP Glafenine results in decreased expression of CYP2A2 mRNA CTD PMID:24136188 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP2B1 mRNA CTD PMID:24136188 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Glafenine results in decreased expression of CYP2C11 mRNA CTD PMID:24136188 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP2D1 mRNA CTD PMID:24136188 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 decreases expression EXP Glafenine results in decreased expression of CYP2D2 mRNA CTD PMID:24136188 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Glafenine results in decreased expression of CYP2D3 mRNA CTD PMID:24136188 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases expression EXP Glafenine results in decreased expression of CYP2D4 mRNA CTD PMID:24136188 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP2E1 mRNA CTD PMID:24136188 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 decreases expression EXP Glafenine results in decreased expression of CYP2J3 mRNA CTD PMID:24136188 NCBI chr 5:115,196,982...115,222,084 JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases expression EXP Glafenine results in decreased expression of CYP2J4 mRNA CTD PMID:24136188 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP2T1 mRNA CTD PMID:24136188 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP39A1 mRNA CTD PMID:24136188 NCBI chr 9:19,804,079...19,880,346
Ensembl chr 9:19,804,079...19,880,346
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP Glafenine results in decreased expression of CYP3A18 mRNA CTD PMID:24136188 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression EXP Glafenine results in decreased expression of CYP3A2 mRNA CTD PMID:24136188 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP3A23-3A1 mRNA CTD PMID:24136188 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP4A1 mRNA CTD PMID:24136188 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP Glafenine results in decreased expression of CYP4F1 mRNA CTD PMID:24136188 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 decreases expression EXP Glafenine results in decreased expression of CYP4F4 mRNA CTD PMID:24136188 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Dad1 defender against cell death 1 increases expression EXP Glafenine results in increased expression of DAD1 mRNA CTD PMID:24136188 NCBI chr15:32,868,136...32,887,933
Ensembl chr15:32,868,087...32,888,095
JBrowse link
G Dao D-amino-acid oxidase decreases expression EXP Glafenine results in decreased expression of DAO mRNA CTD PMID:24136188 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Dap death-associated protein increases expression EXP Glafenine results in increased expression of DAP mRNA CTD PMID:24136188 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 decreases expression EXP Glafenine results in decreased expression of DCAF11 mRNA CTD PMID:24136188 NCBI chr15:34,233,840...34,244,512
Ensembl chr15:34,234,193...34,244,504
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression EXP Glafenine results in decreased expression of DCAF6 mRNA CTD PMID:24136188 NCBI chr13:83,578,730...83,680,330
Ensembl chr13:83,579,036...83,680,207
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression EXP Glafenine results in decreased expression of DCUN1D4 mRNA CTD PMID:24136188 NCBI chr14:37,210,721...37,294,517
Ensembl chr14:37,210,721...37,294,472
JBrowse link
G Dda1 DET1 and DDB1 associated 1 increases expression EXP Glafenine results in increased expression of DDA1 mRNA CTD PMID:24136188 NCBI chr16:19,877,873...19,885,501
Ensembl chr16:19,881,122...19,885,500
JBrowse link
G Ddc dopa decarboxylase decreases expression EXP Glafenine results in decreased expression of DDC mRNA CTD PMID:24136188 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Glafenine results in increased expression of DDIT3 mRNA CTD PMID:24136188 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression EXP Glafenine results in increased expression of DDOST mRNA CTD PMID:24136188 NCBI chr 5:156,668,924...156,676,036
Ensembl chr 5:156,668,712...156,676,035
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression EXP Glafenine results in increased expression of DDX39A mRNA CTD PMID:24136188 NCBI chr19:24,846,530...24,854,886
Ensembl chr19:24,846,938...24,854,953
JBrowse link
G Ddx39b DExD-box helicase 39B increases expression EXP Glafenine results in increased expression of DDX39B mRNA CTD PMID:24136188 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
JBrowse link
G Ddx49 DEAD-box helicase 49 increases expression EXP Glafenine results in increased expression of DDX49 mRNA CTD PMID:24136188 NCBI chr16:20,873,585...20,881,312
Ensembl chr16:20,873,642...20,881,439
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 decreases expression EXP Glafenine results in decreased expression of DECR2 mRNA CTD PMID:24136188 NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Dek DEK proto-oncogene decreases expression EXP Glafenine results in decreased expression of DEK mRNA CTD PMID:24136188 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Dennd6a DENN domain containing 6A decreases expression EXP Glafenine results in decreased expression of DENND6A mRNA CTD PMID:24136188 NCBI chr16:2,278,701...2,327,062
Ensembl chr16:2,278,701...2,327,062
JBrowse link
G Depdc7 DEP domain containing 7 decreases expression EXP Glafenine results in decreased expression of DEPDC7 mRNA CTD PMID:24136188 NCBI chr 3:94,665,714...94,687,013
Ensembl chr 3:94,665,717...94,686,989
JBrowse link
G Dera deoxyribose-phosphate aldolase decreases expression EXP Glafenine results in decreased expression of DERA mRNA CTD PMID:24136188 NCBI chr 4:171,748,254...171,826,414
Ensembl chr 4:171,748,273...171,826,409
JBrowse link
G Derl1 derlin 1 increases expression EXP Glafenine results in increased expression of DERL1 mRNA CTD PMID:24136188 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852
JBrowse link
G