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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carmustine
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Accession:CHEBI:3423 term browser browse the term
Definition:A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Synonyms:exact_synonym: 1,3-bis(2-chloroethyl)-1-nitrosourea
 related_synonym: BCNU;   Bicnu (TN);   Bischloroethyl nitrosourea;   Formula=C5H9Cl2N3O2;   Gliadel;   InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11);   InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N;   N,N'-Bis(2-chloroethyl)-N-nitrosourea;   SMILES=ClCCNC(=O)N(CCCl)N=O;   carmustina;   carmustinum
 xref: CAS:154-93-8;   DrugBank:DB00262;   Drug_Central:512;   KEGG:D00254
 xref_mesh: MESH:D002330
 xref: Wikipedia:Carmustine


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carmustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MGMT O-6-methylguanine-DNA methyltransferase decreases response to substance
multiple interactions		 EXP MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine
MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]		 CTD PMID:14617759 PMID:15053863 NCBI chr28:38,204,611...38,427,482
Ensembl chr28:38,204,610...38,427,380 		JBrowse link
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  CHEBI ontology 495
    role 495
      application 453
        pharmaceutical 447
          drug 447
            antineoplastic agent 321
              carmustine 1
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  CHEBI ontology 495
    subatomic particle 495
      composite particle 495
        hadron 495
          baryon 495
            nucleon 495
              atomic nucleus 495
                atom 495
                  main group element atom 488
                    p-block element atom 488
                      carbon group element atom 477
                        carbon atom 476
                          organic molecular entity 476
                            heteroorganic entity 472
                              organochalcogen compound 426
                                organooxygen compound 424
                                  carbon oxoacid 365
                                    carboxylic acid 365
                                      carboacyl group 306
                                        univalent carboacyl group 306
                                          carbamoyl group 304
                                            carboxamide 304
                                              monocarboxylic acid amide 274
                                                urea 9
                                                  ureas 7
                                                    N-nitrosoureas 1
                                                      carmustine 1
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