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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carmustine
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Accession:CHEBI:3423 term browser browse the term
Definition:A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Synonyms:exact_synonym: 1,3-bis(2-chloroethyl)-1-nitrosourea
 related_synonym: BCNU;   Bicnu (TN);   Bischloroethyl nitrosourea;   Formula=C5H9Cl2N3O2;   Gliadel;   InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11);   InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N;   N,N'-Bis(2-chloroethyl)-N-nitrosourea;   SMILES=ClCCNC(=O)N(CCCl)N=O;   carmustina;   carmustinum
 xref: CAS:154-93-8;   DrugBank:DB00262;   Drug_Central:512;   KEGG:D00254
 xref_mesh: MESH:D002330
 xref: Wikipedia:Carmustine


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carmustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MGMT O-6-methylguanine-DNA methyltransferase decreases response to substance
multiple interactions		 EXP MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine
MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]		 CTD PMID:14617759 PMID:15053863 NCBI chr28:38,204,611...38,427,482
Ensembl chr28:38,204,610...38,427,380 		JBrowse link
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  CHEBI ontology 499
    role 499
      application 457
        pharmaceutical 451
          drug 451
            antineoplastic agent 324
              carmustine 1
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  CHEBI ontology 499
    subatomic particle 499
      composite particle 499
        hadron 499
          baryon 499
            nucleon 499
              atomic nucleus 499
                atom 499
                  main group element atom 492
                    p-block element atom 492
                      carbon group element atom 481
                        carbon atom 480
                          organic molecular entity 480
                            heteroorganic entity 476
                              organochalcogen compound 430
                                organooxygen compound 428
                                  carbon oxoacid 368
                                    carboxylic acid 368
                                      carboacyl group 307
                                        univalent carboacyl group 307
                                          carbamoyl group 305
                                            carboxamide 305
                                              monocarboxylic acid amide 275
                                                urea 9
                                                  ureas 7
                                                    N-nitrosoureas 1
                                                      carmustine 1
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