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3-hydroxypyruvic acid - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-hydroxypyruvic acid
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Accession:CHEBI:30841 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Synonyms:related_synonym: 3-Hydroxy-2-oxopropanoic acid;   Formula=C3H4O4;   Hydroxypyruvic acid;   InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7);   InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N;   SMILES=OCC(=O)C(O)=O
 alt_id: CHEBI:20083;   CHEBI:39999;   CHEBI:5813
 xref: CAS:1113-60-6;   DrugBank:DB02951;   HMDB:HMDB0001352;   KEGG:C00168;   KNApSAcK:C00007563
 xref_mesh: MESH:C012375
 xref: PDBeChem:3PY;   PMID:13163046;   PMID:13328834;   PMID:13522577;   PMID:13522578;   PMID:13564115;   PMID:13798280;   PMID:20989501;   Reaxys:1721079;   Wikipedia:Hydroxypyruvic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:17180

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3-hydroxypyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      biological role 20814
        biochemical role 20261
          cofactor 16912
            pyruvic acid 54
              3-hydroxypyruvic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            heteroorganic entity 20215
                              organochalcogen compound 19902
                                organooxygen compound 19804
                                  carbon oxoacid 19150
                                    carboxylic acid 19147
                                      monocarboxylic acid 18300
                                        fatty acid 16989
                                          saturated fatty acid 16681
                                            propionic acid 3890
                                              pyruvic acid 54
                                                3-hydroxypyruvic acid 2
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