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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fosfomycin
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Accession:CHEBI:28915 term browser browse the term
Definition:A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus.
Synonyms:related_synonym: (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid;   (1R,2S)-epoxypropylphosphonic acid;   (2R-cis)-(3-Methyloxiranyl)phosphonic acid;   1R-cis-(1,2-epoxypropyl)phosphonic acid;   FCM;   Formula=C3H7O4P;   InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1;   InChIKey=YMDXZJFXQJVXBF-STHAYSLISA-N;   L-cis-1,2-epoxypropylphosphonic acid;   Phosphomycin;   Phosphonomycin;   SMILES=C[C@@H]1O[C@@H]1P(O)(O)=O;   [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;   cis-(1R,2S)-epoxypropylphosphonic acid;   fosfomicina;   fosfomycine;   fosfomycinum;   phosphonemycin
 alt_id: CHEBI:24100;   CHEBI:42503;   CHEBI:8159
 xref: CAS:23155-02-4;   DrugBank:DB00828;   Drug_Central:1243;   KEGG:C06454;   KEGG:D04253;   KNApSAcK:C00000789
 xref_mesh: MESH:D005578
 xref: MetaCyc:CPD0-1113;   PDBeChem:FCN;   PMID:105327;   PMID:17124631;   PMID:19308743;   PMID:2660079;   PMID:288976;   PMID:3464490;   PMID:3900889;   PMID:488578;   PMID:614140;   PMID:6348659;   PMID:6796449;   PMID:7030849;   PMID:7224844;   PMID:740308;   PMID:9309262;   Reaxys:1680831
 cyclic_relationship: is_conjugate_acid_of CHEBI:62247


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fosfomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp5 aquaporin 5 decreases expression EXP Fosfomycin results in decreased expression of AQP5 protein CTD PMID:30031112 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Crp C-reactive protein decreases expression ISO Fosfomycin results in decreased expression of CRP protein CTD PMID:12680319 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        antimicrobial agent 18166
          fosfomycin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteromonocyclic compound 17804
                                    saturated organic heteromonocyclic parent 11296
                                      oxirane 11276
                                        epoxide 11275
                                          fosfomycin 2
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