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N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide
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Accession:CHEBI:177876 term browser browse the term
Definition:A member of the class of benzimidazoles that is 1H-benzimidazole substituted by 4-phenoxybenzyl and (methylsulfonyl)amino groups at positions 2 and 6, respectively. It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor.
Synonyms:exact_synonym: N-[2-(4-phenoxybenzyl)-1H-benzimidazol-6-yl]methanesulfonamide
 related_synonym: Formula=C21H19N3O3S;   InChI=1S/C21H19N3O3S/c1-28(25,26)24-16-9-12-19-20(14-16)23-21(22-19)13-15-7-10-18(11-8-15)27-17-5-3-2-4-6-17/h2-12,14,24H,13H2,1H3,(H,22,23);   InChIKey=YOUFPIVQKJMXMT-UHFFFAOYSA-N;   N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulphonamide;   SMILES=CS(=O)(=O)NC1=CC2=C(C=C1)N=C(CC1=CC=C(OC3=CC=CC=C3)C=C1)N2;   XK2
 xref: Chemspider:8041057;   PMID:15056006;   PMID:20082612;   Patent:WO2001032174

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  CHEBI ontology 20856
    role 20816
      biological role 20814
        pharmacological role 19906
          antagonist 17589
            excitatory amino acid antagonist 11639
              NMDA receptor antagonist 10376
                N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 0
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  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      chalcogen 20489
                        oxygen atom 20455
                          oxygen molecular entity 20455
                            hydroxides 20228
                              oxoacid 19285
                                chalcogen oxoacid 13893
                                  sulfur oxoacid 13684
                                    sulfonic acid 11712
                                      sulfonic acid derivative 11712
                                        sulfonamide 5380
                                          N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 0
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