Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:NMDA receptor antagonist
go back to main search page
Accession:CHEBI:60643 term browser browse the term
Definition:Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Synonyms:related_synonym: N-methyl-D-aspartate receptor antagonist;   N-methyl-D-aspartate receptor antagonists;   NMDA receptor antagonists;   NMDAR antagonist;   NMDAR antagonists
 alt_id: CHEBI:60797


show annotations for term's descendants       view all columns           Sort by:
 





Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        pharmacological role 18695
          antagonist 15808
            excitatory amino acid antagonist 10035
              NMDA receptor antagonist 8543
                (1R,2S)-nortilidine + 0
                (R)-ketamine 0
                (R,R)-tramadol + 25
                (R,R)-tramadol hydrochloride + 0
                (S,S)-tramadol + 25
                (S,S)-tramadol hydrochloride + 0
                2-amino-5-phosphonopentanoic acid 0
                7-chlorokynurenic acid 1
                CGP 78608 0
                CGP 78608 hydrochloride 0
                amantadine 10
                amantadine hydrochloride 0
                amantadine sulfate 0
                dextromethorphan + 39
                dinitrogen oxide 8
                esketamine + 0
                esketamine hydrochloride 0
                ethanol + 8042
                ginsenoside Rb3 0
                isoliquiritigenin + 72
                ketamine + 815
                ketamine hydrochloride + 0
                kynurenic acid + 12
                memantine 15
                memantine hydrochloride 0
                orphenadrine + 418
                orphenadrine citrate 0
                orphenadrine hydrochloride 0
                pentamidine 31
                phencyclidine 89
                rolicyclidine 0
                tenocyclidine 0
                tramadol 25
                tramadol hydrochloride 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.