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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Bifeprunox
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Accession:CHEBI:177517 term browser browse the term
Synonyms:exact_synonym: 7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
 related_synonym: Formula=C24H23N3O2;   InChI=1S/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28);   InChIKey=CYGODHVAJQTCBG-UHFFFAOYSA-N;   SMILES=O1C=2C(N3CCN(CC3)CC4=CC(=CC=C4)C5=CC=CC=C5)=CC=CC2NC1=O
 xref: CAS:350992-10-8;   Chemspider:181044;   DrugBank:DB04888;   KEGG:D06566
 xref_mesh: MESH:C509981


show annotations for term's descendants           Sort by:
Bifeprunox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to bifeprunox CTD PMID:15996562 NCBI chr 2:38,427,169...38,431,733 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP bifeprunox results in increased expression of PRKACA protein CTD PMID:26894264 NCBI chr19:41,059,843...41,083,189 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      molecular entity 19895
        polyatomic entity 19847
          molecule 19739
            cyclic compound 19534
              ring assembly 9224
                biphenyls 6268
                  Bifeprunox 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            organic molecule 19724
                              organic cyclic compound 19516
                                carbocyclic compound 18612
                                  benzenoid aromatic compound 18040
                                    biphenyls 6268
                                      Bifeprunox 2
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