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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:porphobilinogen
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Accession:CHEBI:17381 term browser browse the term
Definition:A dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively.
Synonyms:related_synonym: 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID;   Formula=C10H14N2O4;   InChI=1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16);   InChIKey=QSHWIQZFGQKFMA-UHFFFAOYSA-N;   SMILES=NCc1[nH]cc(CCC(O)=O)c1CC(O)=O
 alt_id: CHEBI:14867;   CHEBI:26212;   CHEBI:44832;   CHEBI:8335
 xref: Beilstein:220051;   CAS:487-90-1;   DrugBank:DB02272;   HMDB:HMDB0000245;   KEGG:C00931;   KNApSAcK:C00007339
 xref_mesh: MESH:D011162
 xref: MetaCyc:PORPHOBILINOGEN;   PDBeChem:PBG;   PMID:21383008;   PMID:21627493;   PMID:22279024;   PMID:22740490;   PMID:22770225;   PMID:22974111;   Reaxys:220051;   Wikipedia:Porphobilinogen
 cyclic_relationship: is_conjugate_acid_of CHEBI:58126


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porphobilinogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase multiple interactions EXP [cadmium acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; [Zinc Acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen CTD PMID:21360559 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Fech ferrochelatase multiple interactions ISO [Porphobilinogen results in decreased activity of FECH protein] which results in increased abundance of Iron CTD PMID:15078340 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        biochemical role 19529
          metabolite 19515
            porphobilinogen 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  heteroarene 17135
                                    monocyclic heteroarene 14869
                                      azole 14371
                                        pyrroles 5928
                                          porphobilinogen 2
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