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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-acetylneuraminic acid
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Accession:CHEBI:17012 term browser browse the term
Definition:An N-acylneuraminic acid where the N-acyl group is specified as acetyl.
Synonyms:exact_synonym: 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid
 related_synonym: 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid;   Aceneuramic acid;   Formula=C11H19NO9;   InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11?/m0/s1;   InChIKey=SQVRNKJHWKZAKO-LUWBGTNYSA-N;   Neu5Ac;   NeuAc;   O-sialic acid;   SMILES=[H][C@]1(OC(O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO;   WURCS=2.0/1,1,0/[Aad21122h-2x_2-6_5*NCC/3=O]/1/;   acide aceneuramique;   acidium aceneuramicum;   acido aceneuramico
 alt_id: CHEBI:21620;   CHEBI:7214
 xref: Beilstein:2951361;   CAS:131-48-6;   GlyGen:G81533KY;   GlyTouCan:G81533KY;   KEGG:C00270;   KNApSAcK:C00019584
 xref_mesh: MESH:D019158
 xref: PMID:14960498;   PMID:16209099;   PMID:16624269;   PMID:18487279;   PMID:19329108;   PMID:7508418;   PMID:8448384;   Reaxys:1398688;   Wikipedia:N-acetylneuraminic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:35418


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N-acetylneuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of N-Acetylneuraminic Acid; CMAS protein affects the abundance of N-Acetylneuraminic Acid analog CTD PMID:27380425 NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase increases chemical synthesis EXP GNE protein results in increased chemical synthesis of N-Acetylneuraminic Acid CTD PMID:9305888 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499 		JBrowse link
G Nans N-acetylneuraminate synthase increases chemical synthesis ISO NANS results in increased chemical synthesis of N-Acetylneuraminic Acid CTD PMID:27213289 NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950 		JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      chemical role 19451
        antioxidant 16140
          N-acetylneuraminic acid 3
            3-acetamido-3,5-dideoxy-L-lyxo-hept-6-ulopyranosuronic acid 0
            5-acetamido-3,5-dideoxy-L-arabino-hept-2-ulopyranosonic acid 0
            9-deoxy-9-acetamido-N-acetyl-alpha-neuraminic acid 0
            N-acetyl-alpha-neuraminic acid + 0
            N-acetyl-beta-neuraminic acid + 1
            N-acetylneuraminamide + 0
            N-acetylneuraminol + 0
            N-acetylneuraminyl group 0
            beta-D-Galp-(1->9)-Neup5Ac 0
            ethyl N-acetylneuraminate 0
            methyl N-acetylneuraminate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbohydrates and carbohydrate derivatives 15285
                                    carbohydrate 15285
                                      carbohydrate acid 927
                                        ketoaldonic acid 782
                                          ketoaldonic acid derivative 3
                                            neuraminic acids 3
                                              sialic acid 3
                                                N-acylneuraminic acid 3
                                                  N-acetylneuraminic acids 3
                                                    N-acetylneuraminic acid 3
                                                      3-acetamido-3,5-dideoxy-L-lyxo-hept-6-ulopyranosuronic acid 0
                                                      5-acetamido-3,5-dideoxy-L-arabino-hept-2-ulopyranosonic acid 0
                                                      9-deoxy-9-acetamido-N-acetyl-alpha-neuraminic acid 0
                                                      N-acetyl-alpha-neuraminic acid + 0
                                                      N-acetyl-beta-neuraminic acid + 1
                                                      N-acetylneuraminamide + 0
                                                      N-acetylneuraminol + 0
                                                      N-acetylneuraminyl group 0
                                                      beta-D-Galp-(1->9)-Neup5Ac 0
                                                      ethyl N-acetylneuraminate 0
                                                      methyl N-acetylneuraminate 0
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