ketoaldonic acid - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	ketoaldonic acid	go back to main search page
Accession:	CHEBI:24963	browse the term
Definition:	Oxo carboxylic acids formally derived from aldonic acids by replacement of a secondary CHOH group by a carbonyl group.
Synonyms:	related_synonym:	ketoaldonic acids

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Genes (814)

L-ascorbic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868

G

alanyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of AARS1 mRNA

NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497

G

ATP binding cassette subfamily A member 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [T0901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]

PMID:17639512 PMID:25932594

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473

G

ATP binding cassette subfamily B member 1A

multiple interactions

ISO
EXP

Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]

PMID:22914566 PMID:31739238

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP binding cassette subfamily C member 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]

PMID:22914566 PMID:34480604

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily C member 2

multiple interactions

ISO
EXP

Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein]

PMID:19326901 PMID:22914566 PMID:31005848

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

aggrecan

multiple interactions

ISO

[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]]

NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ACAP1 mRNA]

NCBI chr10:55,104,040...55,119,280
Ensembl chr10:55,104,040...55,118,185

G

angiotensin I converting enzyme

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein]

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

angiotensin converting enzyme 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ACE2 mRNA

NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596

G

acetylcholinesterase

decreases activity
multiple interactions
increases activity

ISO
EXP

Ascorbic Acid results in decreased activity of ACHE protein
[Dexamethasone co-treated with Ascorbic Acid] results in increased expression of ACHE mRNA; [Dexamethasone co-treated with Ascorbic Acid] results in increased expression of and results in increased activity of ACHE protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased activity of ACHE protein]
Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein]
Ascorbic Acid results in increased activity of ACHE protein
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]

PMID:11814146 PMID:16248992 PMID:16822217 PMID:19703495 PMID:20663516 More...

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

acyl-CoA synthetase long-chain family member 4

decreases expression

EXP

Ascorbic Acid results in decreased expression of ACSL4 mRNA

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261

G

acyl-CoA synthetase long-chain family member 5

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA

NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943

G

actin alpha 2, smooth muscle

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of ACTA2 protein
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Mercaptoethanol co-treated with Ascorbic Acid] results in increased expression of ACTA2 protein; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA]

PMID:7593635 PMID:17053324 PMID:18607632 PMID:27381660

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

actinin alpha 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA

NCBI chr17:62,835,055...62,902,331
Ensembl chr17:62,812,988...62,903,552

G

ADAM metallopeptidase domain 30

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of ADAM30 mRNA]

NCBI chr 2:188,440,918...188,444,358
Ensembl chr 2:188,440,918...188,444,358

G

adenylate cyclase 6

decreases expression

ISO

Ascorbic Acid results in decreased expression of ADCY6 mRNA

NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770

G

adhesion G protein-coupled receptor L1

decreases expression

EXP

Ascorbic Acid results in decreased expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:41,109,117...41,148,896

G

alpha-fetoprotein

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

argonaute RISC catalytic component 2

decreases expression

EXP

Ascorbic Acid results in decreased expression of AGO2 mRNA

NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980

G

angiotensinogen

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein]
[Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]; Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]

PMID:20881940 PMID:26111765 PMID:31144504

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

adenylate kinase 4

decreases expression

ISO

Ascorbic Acid results in decreased expression of AK4 mRNA

NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401

G

aldo-keto reductase family 1 member A1

decreases abundance
multiple interactions

ISO

AKR1A1 gene mutant form results in decreased abundance of Ascorbic Acid
[AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine] which results in decreased abundance of Ascorbic Acid; AKR1A1 gene mutant form promotes the reaction [Diethylnitrosamine results in decreased abundance of Ascorbic Acid]

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldo-keto reductase family 1 member B1

increases reduction

ISO

Ascorbic Acid results in increased reduction of AKR1B1 protein modified form

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1 member B10

increases expression

ISO

Ascorbic Acid results in increased expression of AKR1B10 mRNA

NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847

G

aldo-keto reductase family 1, member C2

increases expression

ISO

Ascorbic Acid results in increased expression of AKR1C2 mRNA

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686

G

AKT serine/threonine kinase 1

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein]

PMID:21262251 PMID:21911000

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

AKT serine/threonine kinase 2

affects expression

ISO

Ascorbic Acid affects the expression of AKT2 mRNA

NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420

G

5'-aminolevulinate synthase 1

multiple interactions

ISO

[Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]

NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642

G

albumin

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 2 family member

multiple interactions

ISO

ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin]

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

aldolase, fructose-bisphosphate A

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

alkaline phosphatase, intestinal

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ALPI mRNA

NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780

G

alkaline phosphatase, biomineralization associated

multiple interactions
increases expression

ISO
EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of ALPL mRNA]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of ALPL mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of ALPL mRNA]
Ascorbic Acid results in increased expression of ALPL mRNA

PMID:26424790 PMID:26492236 PMID:28105418 PMID:28921615 PMID:37704839 More...

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

anti-Mullerian hormone receptor type 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA

NCBI chr 7:135,454,517...135,470,183
Ensembl chr 7:135,457,922...135,471,104

G

alanyl aminopeptidase, membrane

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

annexin A1

multiple interactions
increases expression

ISO
EXP

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA
Ascorbic Acid results in increased expression of ANXA1 mRNA

PMID:15372504 PMID:17639512 PMID:34480604

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A2

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ANXA2 mRNA]

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A5

multiple interactions
increases expression

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 protein

PMID:15372504 PMID:17917374 PMID:19224539

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

apolipoprotein A1

decreases expression
multiple interactions
decreases activity

ISO
EXP

Ascorbic Acid results in decreased expression of APOA1 mRNA; Ascorbic Acid results in decreased expression of APOA1 protein
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA
Ascorbic Acid results in decreased activity of APOA1 promoter

PMID:16423621 PMID:34480604

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729

G

apolipoprotein B

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA; Ascorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Ascorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]

PMID:17475462 PMID:17639512

NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814

G

apolipoprotein E

increases expression

EXP

Ascorbic Acid results in increased expression of APOE mRNA

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

apolipoprotein M

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNA

NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218

G

amyloid beta precursor protein

multiple interactions
decreases abundance
increases oxidation

EXP
ISO

Ascorbic Acid inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species]; resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Ascorbic Acid]
APP protein modified form results in increased oxidation of Ascorbic Acid
[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines; [APP protein modified form binds to Copper] which results in increased oxidation of Ascorbic Acid; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; APP protein inhibits the reaction [Copper results in increased oxidation of Ascorbic Acid]; APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]; Copper promotes the reaction [APP protein modified form results in increased oxidation of Ascorbic Acid]; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Penicillamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]

PMID:15030205 PMID:17964426 PMID:24276282 PMID:25654502

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

aquaporin 3 (Gill blood group)

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685

G

Rho GDP dissociation inhibitor alpha

increases expression
multiple interactions

ISO
EXP

Ascorbic Acid results in increased expression of ARHGDIA mRNA
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in decreased expression of ARHGDIA mRNA]

PMID:22139585 PMID:39325335

NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347

G

Rho GDP dissociation inhibitor beta

multiple interactions
increases expression

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of ARHGDIB mRNA
Ascorbic Acid results in increased expression of ARHGDIB protein

PMID:17639512 PMID:22139585

NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068

G

actin related protein 2/3 complex, subunit 5

increases expression

ISO

Ascorbic Acid results in increased expression of ARPC5 mRNA; Ascorbic Acid results in increased expression of ARPC5 protein

NCBI chr13:67,454,379...67,463,288
Ensembl chr13:67,437,027...67,463,283

G

achaete-scute family bHLH transcription factor 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA

NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:23,790,360...23,798,231

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

ISO

Ascorbic Acid results in decreased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050

G

ATPase family, AAA domain containing 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of ATAD2 mRNA

NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238

G

ATPase family, AAA domain containing 2B

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ATAD2B mRNA

NCBI chr 6:33,646,075...33,789,532
Ensembl chr 6:33,646,075...33,789,532

G

activating transcription factor 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

ATM serine/threonine kinase

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA
Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form]

PMID:17917374 PMID:25977998

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

ATP synthase F1 subunit beta

increases expression

ISO

Ascorbic Acid results in increased expression of ATP5F1B protein

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462

G

ATPase H+ transporting V1 subunit A

increases expression

ISO

Ascorbic Acid results in increased expression of ATP6V1A mRNA

NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603

G

aurora kinase B

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of AURKB mRNA

NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285

G

activator of transcription and developmental regulator AUTS2

increases expression

ISO

Ascorbic Acid results in increased expression of AUTS2 mRNA

NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386

G

beta-2 microglobulin

increases expression

EXP

Ascorbic Acid results in increased expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

BTB domain and CNC homolog 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of BACH1 protein]

NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277

G

BCL2-associated agonist of cell death

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein]
[juglone co-treated with Ascorbic Acid] results in increased expression of BAD protein

PMID:21262251 PMID:29992683

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BCL2-antagonist/killer 1

multiple interactions

ISO

[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974

G

BCL2 associated X, apoptosis regulator

multiple interactions

ISO
EXP

[Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased expression of BAX protein; [juglone co-treated with Ascorbic Acid] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of BAX mRNA]
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Humic Substances results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]

PMID:17166419 PMID:17959157 PMID:18683188 PMID:18758938 PMID:21262251 More...

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

Bcl-2 binding component 3

multiple interactions

ISO

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666

G

butyrylcholinesterase

multiple interactions

ISO

[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein]

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

BCL2, apoptosis regulator

decreases expression
multiple interactions
increases abundance

ISO
EXP

Ascorbic Acid results in decreased expression of BCL2 mRNA
Ascorbic Acid inhibits the reaction [glycidamide results in decreased expression of BCL2 mRNA]
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 protein]
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Humic Substances results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ascorbic Acid promotes the reaction [lead acetate results in increased expression of BCL2 protein]
BCL2 protein results in increased abundance of Ascorbic Acid

PMID:15449323 PMID:17166419 PMID:17959157 PMID:18683188 PMID:18758938 More...

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

Bcl2-like 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]

PMID:18758938 PMID:21262251

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 14

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of BCL2L14 mRNA

NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079

G

Bcl2-like 2

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA

NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379

G

beta-carotene oxygenase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]

NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917

G

brain-derived neurotrophic factor

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of BDNF mRNA
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein

PMID:15305145 PMID:33713149

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

bone gamma-carboxyglutamate protein

multiple interactions
affects binding

ISO
EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Copper] affects the cleavage of BGLAP3 protein; [Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BGLAP mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
BGLAP3 protein binds to Ascorbic Acid
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]]

PMID:11396734 PMID:12510807 PMID:17692823 PMID:25932594 PMID:26492236 More...

NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318

G

BH3 interacting domain death agonist

multiple interactions

ISO

[juglone co-treated with Ascorbic Acid] affects the expression of BID protein

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275

G

baculoviral IAP repeat-containing 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of BIRC3 mRNA

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590

G

baculoviral IAP repeat-containing 5

decreases expression

ISO

Ascorbic Acid results in decreased expression of BIRC5 mRNA

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

bone morphogenetic protein 1

multiple interactions

EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNA

NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485

G

bone morphogenetic protein 2

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]

PMID:15994055 PMID:26492236 PMID:27387537

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760

G

bone morphogenetic protein 3

multiple interactions

EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP3 mRNA

NCBI chr14:11,012,564...11,041,282
Ensembl chr14:11,016,620...11,041,282

G

bone morphogenetic protein 4

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172

G

bone morphogenetic protein 5

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA

NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189

G

bone morphogenetic protein 7

multiple interactions

EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP7 mRNA

NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137

G

bone morphogenetic protein receptor type 1A

multiple interactions

EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]]

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

bone morphogenetic protein receptor type 1B

increases expression

ISO

Ascorbic Acid results in increased expression of BMPR1B mRNA

NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:233,211,525...233,544,311

G

BUB1 mitotic checkpoint serine/threonine kinase

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921

G

complement C3

increases expression

EXP

Ascorbic Acid results in increased expression of C3 mRNA

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C5

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Ascorbic Acid inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein]

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

similar to human chromosome 11 open reading frame 54

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of BKGD mRNA
[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of BKGD mRNA

NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811

G

carbonic anhydrase 9

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein]

NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626

G

calcium voltage-gated channel subunit alpha1 H

decreases activity
multiple interactions

ISO

Ascorbic Acid results in decreased activity of CACNA1H protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]

NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771

G

calbindin 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CALB2 protein]

NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952

G

calcium/calmodulin-dependent protein kinase II delta

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of CAMK2D mRNA]

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276

G

carbonic anhydrase 2

increases expression

ISO

Ascorbic Acid results in increased expression of CAR2 mRNA

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064

G

caspase 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein]

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

multiple interactions
increases expression
decreases activity

ISO
EXP

[Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased cleavage of CASP3 protein; [Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA]; [juglone co-treated with Ascorbic Acid] results in decreased expression of CASP3 protein; Ascorbic Acid inhibits the reaction [[chromium hexavalent ion co-treated with Antimycin A] results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[chromium hexavalent ion co-treated with Rotenone] results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Antimycin A results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [hydroxyethyl methacrylate results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [triethylene glycol dimethacrylate results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of CASP3 mRNA]
Ascorbic Acid results in increased expression of CASP3 mRNA
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]
Ascorbic Acid results in decreased activity of CASP3 protein

PMID:12750841 PMID:15158148 PMID:16124896 PMID:16407847 PMID:16867262 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 4

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA]

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727

G

caspase 6

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein]

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726

G

caspase 7

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein]

PMID:17301063 PMID:17879260

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 8

multiple interactions
increases expression

EXP
ISO

[Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA
Ascorbic Acid results in increased expression of CASP8 mRNA
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]

PMID:18544905 PMID:20400526 PMID:23711929 PMID:30597948

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 9

multiple interactions

EXP
ISO

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in increased expression of CASP9 mRNA]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]

PMID:15158148 PMID:16973328 PMID:23711929 PMID:33372294

Ensembl chr 5:159,391,188...159,409,648

G

calpastatin

increases expression

EXP

Ascorbic Acid results in increased expression of CAST mRNA

NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180

G

catalase

affects expression
increases expression
increases activity
decreases activity
multiple interactions
decreases response to substance

ISO
EXP

Ascorbic Acid affects the expression of CAT protein
Ascorbic Acid results in increased expression of CAT mRNA
Ascorbic Acid results in increased activity of CAT protein
Ascorbic Acid results in decreased activity of CAT protein
2-aminoethoxydiphenyl borate inhibits the reaction [Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in decreased expression of CAT mRNA]]; [[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Lead] results in increased expression of CAT protein; [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased activity of CAT protein]; [Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ascorbic Acid inhibits the reaction [abamectin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [Food Additives affects the activity of CAT protein]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; [juglone co-treated with Ascorbic Acid] results in decreased activity of CAT protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [hydroxyethyl methacrylate results in increased degradation of CAT mRNA]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [triethylene glycol dimethacrylate results in increased degradation of CAT mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; CAT protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ascorbic Acid]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]
Ascorbic Acid results in increased expression of CAT protein
[Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]; [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
CAT protein results in decreased susceptibility to Ascorbic Acid

PMID:10772068 PMID:12540038 PMID:12767684 PMID:14698046 PMID:15104111 More...

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolin 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein]

NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740

G

cystathionine beta synthase

decreases expression

ISO

Ascorbic Acid results in decreased expression of CBS mRNA

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066

G

C-C motif chemokine ligand 2

affects expression
decreases expression

ISO

Ascorbic Acid affects the expression of CCL2 mRNA; Ascorbic Acid deficiency affects the expression of CCL2 mRNA
Ascorbic Acid results in decreased expression of CCL2 mRNA

PMID:19932582 PMID:21796779

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 21

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 3

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

cyclin A1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNA1 protein]

NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300

G

cyclin B1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein]

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin C

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA

NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:40,063,623...40,093,370

G

cyclin D1

multiple interactions
decreases expression

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA; Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of CCND1 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND1 protein]
Ascorbic Acid results in decreased expression of CCND1 mRNA

PMID:17917374 PMID:21621607 PMID:21919647 PMID:30140404

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin D2

multiple interactions

ISO
EXP

[Quercetin co-treated with Ascorbic Acid] results in increased expression of CCND2 mRNA
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND2 protein]

PMID:17639512 PMID:21621607

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301

G

cyclin D3

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein]
Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein]

PMID:21621607 PMID:29992683

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033

G

cyclin E2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNE2 protein]

NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882

G

cyclin G1

multiple interactions

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA

PMID:17917374 PMID:18544905

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

CD24 molecule

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA

NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785

G

CD34 molecule

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD34 mRNA

NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315

G

CD40 molecule

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD40 mRNA

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

CD44 molecule

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

Cd48 molecule

increases expression

EXP

Ascorbic Acid results in increased expression of CD48 mRNA

NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942

G

Cd69 molecule

decreases expression

ISO

Ascorbic Acid deficiency results in decreased expression of CD69 protein

NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509

G

Cd82 molecule

increases expression

EXP

Ascorbic Acid results in increased expression of CD82 mRNA

NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744

G

cell division cycle 20

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799

G

cell division cycle 6

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of CDC6 mRNA

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241

G

cadherin 10

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA

NCBI chr 2:70,355,521...70,577,880
Ensembl chr 2:70,357,217...70,578,332

G

cadherin 13

increases expression

ISO

Ascorbic Acid results in increased expression of CDH13 mRNA

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119

G

cadherin 2

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein]

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 22

increases expression

EXP

Ascorbic Acid results in increased expression of CDH22 mRNA

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

cyclin-dependent kinase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK1 protein]

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin dependent kinase 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein]

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase 4

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein]
[juglone co-treated with Ascorbic Acid] results in decreased expression of CDK4 protein

PMID:21621607 PMID:29992683

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase 6

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK6 protein]

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA
Ascorbic Acid results in increased expression of CDKN1A mRNA
[INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in increased expression of CDKN1A mRNA]; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in increased expression of CDKN1A protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A mRNA]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA]

PMID:17917374 PMID:20067818 PMID:20400526 PMID:20530418 PMID:28415704 More...

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

multiple interactions

EXP

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

cyclin-dependent kinase inhibitor 2A

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein]
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN2A mRNA]

PMID:21621607 PMID:36500241

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

CEA cell adhesion molecule 6

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA

NCBI chr 1:89,544,415...89,562,552
Ensembl chr 1:89,544,400...89,562,552

G

CCAAT/enhancer binding protein alpha

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of CEBPA protein
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA

PMID:14505802 PMID:25932594

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309

G

CCAAT/enhancer binding protein beta

increases expression

EXP

Ascorbic Acid results in increased expression of CEBPB mRNA

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072

G

complement factor B

multiple interactions

ISO
EXP

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of CFB mRNA
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of CFB mRNA]

PMID:17639512 PMID:37704839

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

CF transmembrane conductance regulator

multiple interactions
increases activity

ISO

[Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein; Ascorbic Acid inhibits the reaction [Vehicle Emissions results in decreased activity of CFTR protein]; Ascorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides]
Ascorbic Acid results in increased activity of CFTR protein

PMID:14993613 PMID:32374624 PMID:34601066

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

chromatin assembly factor 1 subunit B

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of CHAF1B mRNA

NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733

G

choline O-acetyltransferase

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein]

NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416

G

checkpoint kinase 2

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of CHEK2 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein]

PMID:18544905 PMID:25977998 PMID:31388677

NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667

G

cell death-inducing DFFA-like effector c

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

citron rho-interacting serine/threonine kinase

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of CIT mRNA

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA]

NCBI chr X:71,390,328...71,395,023
Ensembl chr X:71,390,331...71,393,649

G

clusterin

increases expression

EXP

Ascorbic Acid results in increased expression of CLU mRNA

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860

G

c-Maf-inducing protein

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of CMIP mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CMIP mRNA

NCBI chr19:62,213,402...62,419,443
Ensembl chr19:62,213,365...62,417,500

G

calponin 1

multiple interactions
increases expression

ISO
EXP

[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 protein
Ascorbic Acid results in increased expression of CNN1 protein

PMID:14639096 PMID:18607632

NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482

G

cannabinoid receptor 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CNR1 protein]

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

cannabinoid receptor 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CNR2 protein]

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961

G

ciliary neurotrophic factor

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]

NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488

G

contactin 1

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA

NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391

G

contactin associated protein 1

multiple interactions

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CNTNAP1 mRNA

NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,611,890...86,631,730

G

collagen type X alpha 1 chain

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of COL10A1 mRNA
U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of COL10A1 mRNA]

NCBI chr20:39,737,536...39,744,518
Ensembl chr20:39,716,822...39,751,440

G

collagen type I alpha 1 chain

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of COL1A1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA

PMID:12510807 PMID:14566779 PMID:28105418 PMID:31935364

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of COL1A2 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of COL1A2 mRNA

PMID:15372504 PMID:25555879

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type II alpha 1 chain

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of COL2A1 mRNA
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]

PMID:15372504 PMID:26526931

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

collagen type III alpha 1 chain

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

complement C3d receptor 2

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CR2 mRNA

NCBI chr13:109,207,034...109,244,980
Ensembl chr13:109,213,867...109,244,552

G

cysteine-rich protein 2

increases expression

EXP

Ascorbic Acid results in increased expression of CRIP2 mRNA

NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120

G

C-reactive protein

multiple interactions

ISO

[Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid] results in decreased expression of CRP protein

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

crystallin, alpha B

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of CRYAB mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA

PMID:15372504 PMID:34480604

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

citrate synthase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]

NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938

G

chondroitin sulfate proteoglycan 5

increases expression

ISO

Ascorbic Acid results in increased expression of CSPG5 mRNA

NCBI chr 8:119,098,932...119,113,191
Ensembl chr 8:119,098,925...119,143,907

G

cysteine and glycine-rich protein 1

increases expression

EXP

Ascorbic Acid results in increased expression of CSRP1 mRNA

NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139

G

cystatin E/M

increases expression

EXP

Ascorbic Acid results in increased expression of CST6 mRNA

NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:212,084,676...212,086,384

G

catenin beta 1

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the localization of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein]
[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]; Lithium Chloride affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; Lithium Chloride affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]; T 0070907 affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; T 0070907 affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]

PMID:28921615 PMID:29940330 PMID:30320191

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

CTP synthase 2

multiple interactions

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of CTPS2 mRNA

NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505

G

cathepsin D

multiple interactions

EXP

[ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin K

increases expression

ISO

Ascorbic Acid results in increased expression of CTSK mRNA

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cathepsin O

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of CTSO mRNA

NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:169,528,511...169,554,995

G

C-X-C motif chemokine ligand 1

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid deficiency results in increased expression of CXCL1 mRNA; Ascorbic Acid deficiency results in increased expression of CXCL1 protein
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL1 mRNA]

PMID:16637227 PMID:36500241

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

decreases expression
increases expression

ISO

Ascorbic Acid results in decreased expression of CXCL10 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL2 mRNA]

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL1 mRNA]

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

C-X-C motif chemokine ligand 6

decreases expression
increases expression

ISO

Ascorbic Acid results in decreased expression of CXCL6 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL6 mRNA

NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417

G

C-X-C motif chemokine ligand 9

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

C-X-C motif chemokine receptor 5

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCR5 mRNA

NCBI chr 8:53,738,878...53,756,813
Ensembl chr 8:53,740,197...53,754,816

G

cytochrome b-245 alpha chain

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytochrome b-245 beta chain

increases expression

ISO

Ascorbic Acid results in increased expression of CYBB protein

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065

G

cytochrome b reductase 1

decreases expression
increases expression

ISO

Ascorbic Acid results in decreased expression of CYBRD1 protein
Ascorbic Acid results in increased expression of CYBRD1 protein

NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061

G

cytochrome c, somatic

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein]

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions
increases expression

EXP
ISO

Ascorbic Acid inhibits the reaction [Cadmium results in decreased expression of CYP11A1 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP11A1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 mRNA]
Ascorbic Acid results in increased expression of CYP11A1 mRNA

PMID:15223132 PMID:16298753 PMID:17280759 PMID:17901237

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions
increases expression

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA
Ascorbic Acid results in increased expression of CYP19A1 mRNA

PMID:16443354 PMID:17901237

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
decreases activity

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of CYP1A1 mRNA; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]
Ascorbic Acid results in decreased activity of CYP1A1 protein

PMID:16517059 PMID:17512695 PMID:17639512 PMID:19268519 PMID:21094198

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression

EXP

Ascorbic Acid deficiency results in increased expression of CYP1A2 mRNA; Ascorbic Acid deficiency results in increased expression of CYP1A2 protein

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 24, subfamily a, polypeptide 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA

NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176

G

cytochrome P450, family 2, subfamily b, polypeptide 2

decreases expression

EXP

Ascorbic Acid deficiency results in decreased expression of CYP2B2 protein

NCBI chr 1:90,722,243...90,736,272

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity
multiple interactions

ISO
EXP

Ascorbic Acid results in decreased activity of CYP2E1 protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein]

PMID:17512695 PMID:31585129 PMID:31739238

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

ISO

[Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

DAB adaptor protein 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888

G

D-amino-acid oxidase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Diquat results in increased activity of DAO protein]

NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300

G

DCC netrin 1 receptor

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA

NCBI chr18:67,144,272...68,248,159
Ensembl chr18:67,149,179...68,247,541

G

doublecortin-like kinase 1

increases expression

ISO

Ascorbic Acid results in increased expression of DCLK1 mRNA

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090

G

decorin

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926

G

doublecortin

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA

NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161

G

DNA-damage inducible transcript 3

multiple interactions

EXP

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

dehydrogenase/reductase 9

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA

NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of DKK1 mRNA

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650

G

dickkopf WNT signaling pathway inhibitor 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of DKK2 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of DKK2 promoter]

NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724

G

dihydrolipoamide dehydrogenase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of and results in increased phosphorylation of DLD protein]

NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354

G

discs large MAGUK scaffold protein 4

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA
Ascorbic Acid inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]

PMID:33713149 PMID:33872575

NCBI chr10:55,239,397...55,267,780
Ensembl chr10:55,236,869...55,265,839

G

DLG associated protein 5

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of DLGAP5 mRNA

NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176

G

dentin matrix acidic phosphoprotein 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]

NCBI chr14:5,833,111...5,867,154
Ensembl chr14:5,833,111...5,843,993

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

DnaJ heat shock protein family (Hsp40) member C10

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of DNAJC10 mRNA]

NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368

G

deoxyribonuclease 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of DNASE1 mRNA

NCBI chr10:12,005,305...12,030,615
Ensembl chr10:12,005,306...12,010,497

G

double PHD fingers 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPF1 mRNA

NCBI chr 1:93,729,683...93,743,425
Ensembl chr 1:93,726,970...93,743,425

G

dipeptidylpeptidase 4

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of DPP4 mRNA

NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422

G

developmental pluripotency-associated 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPPA2 mRNA

NCBI chr11:66,008,002...66,020,044
Ensembl chr11:66,011,628...66,020,994

G

developmental pluripotency associated 5

decreases expression

ISO

Ascorbic Acid results in decreased expression of DPPA5A mRNA

NCBI chr 8:88,095,627...88,097,936
Ensembl chr 1:14,260,684...14,261,146

G

dual specificity phosphatase 6

decreases expression

EXP

Ascorbic Acid results in decreased expression of DUSP6 mRNA

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

E2F transcription factor 2

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA

NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:153,682,789...153,706,087

G

EBF transcription factor 3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA

NCBI chr 1:201,426,446...201,544,444
Ensembl chr 1:201,426,450...201,544,305

G

endothelial cell surface expressed chemotaxis and apoptosis regulator

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA

NCBI chr18:27,583,791...27,593,184
Ensembl chr18:27,583,195...27,593,195

G

endothelin 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

endothelin 3

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of EDN3 mRNA

NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329

G

endothelin receptor type B

increases expression

ISO

Ascorbic Acid results in increased expression of EDNRB mRNA

NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765

G

epidermal growth factor receptor

decreases expression

ISO

Ascorbic Acid results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

egl-9 family hypoxia-inducible factor 1

multiple interactions

ISO

EGLN1 mRNA affects the reaction [Ascorbic Acid results in increased expression of SP7 protein]

NCBI chr19:69,765,276...69,804,681

G

egl-9 family hypoxia-inducible factor 3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of EGLN3 mRNA

PMID:17639512 PMID:34480604

NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015

G

eukaryotic translation initiation factor 2 subunit beta

decreases expression

ISO

Ascorbic Acid results in decreased expression of EIF2S2 mRNA

NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570

G

eukaryotic translation initiation factor 3, subunit A

decreases expression

ISO

Ascorbic Acid results in decreased expression of EIF3A mRNA

NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025

G

eukaryotic translation initiation factor 3, subunit C

decreases expression

ISO

Ascorbic Acid results in decreased expression of EIF3C mRNA

NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067

G

eukaryotic translation initiation factor 3, subunit I

increases expression

ISO

Ascorbic Acid results in increased expression of EIF3I mRNA

NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232

G

eukaryotic translation initiation factor 4A1

decreases expression

ISO

Ascorbic Acid results in decreased expression of EIF4A1 mRNA

NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602

G

ELAV like RNA binding protein 3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA

NCBI chr 8:28,823,120...28,859,395
Ensembl chr 8:28,825,707...28,859,659

G

ELAV like RNA binding protein 4

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA

NCBI chr 5:130,285,418...130,429,106
Ensembl chr 5:130,285,418...130,429,096

G

elongator acetyltransferase complex subunit 6

multiple interactions
decreases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of ELP6 mRNA
Ascorbic Acid results in decreased expression of ELP6 mRNA

NCBI chr 8:119,158,380...119,173,483
Ensembl chr 8:119,158,396...119,174,244

G

epithelial membrane protein 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNA

NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365

G

epithelial membrane protein 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNA

NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:105,525,088...105,528,265

G

empty spiracles homeobox 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA

NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671

G

engrailed homeobox 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of EN1 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of EN1 promoter]

NCBI chr13:34,303,684...34,309,269
Ensembl chr13:34,303,702...34,309,269

G

enolase 1

multiple interactions
decreases expression

ISO

[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of ENO1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 protein]
Ascorbic Acid results in decreased expression of ENO1 mRNA; Ascorbic Acid results in decreased expression of ENO1 protein

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

endothelial PAS domain protein 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein]

NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729

G

epoxide hydrolase 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

epoxide hydrolase 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

ERCC excision repair 2, TFIIH core complex helicase subunit

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA

NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102

G

ERCC excision repair 4, endonuclease catalytic subunit

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA

NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539

G

ERCC excision repair 5, endonuclease

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA

NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084

G

estrogen receptor 1

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA]
[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein]

PMID:18602937 PMID:28921615

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen receptor 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA]

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709

G

ethanolamine kinase 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of ETNK1 mRNA]

NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of EZH1 mRNA

NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 protein; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA]

NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183

G

coagulation factor III, tissue factor

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

fatty acid binding protein 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113

G

fatty acid binding protein 4

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]

PMID:25062436 PMID:25932594 PMID:32473317

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

fatty acid binding protein 6

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of FABP6 mRNA

NCBI chr10:28,565,054...28,569,727
Ensembl chr10:28,565,054...28,573,058

G

fumarylacetoacetate hydrolase

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA

NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046

G

FA complementation group L

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of FANCL mRNA

NCBI chr14:104,449,403...104,515,297
Ensembl chr14:104,394,590...104,515,297

G

FAT atypical cadherin 1

multiple interactions
increases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FAT1 mRNA
Ascorbic Acid results in increased expression of FAT1 mRNA

NCBI chr16:53,909,759...54,029,175
Ensembl chr16:53,909,556...54,028,609

G

fibulin 1

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of FBLN1 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FBLN1 mRNA

NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965

G

fructose-bisphosphatase 1

affects expression

ISO

Ascorbic Acid affects the expression of FBP1 protein

NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746

G

F-box protein 32

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA

NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491

G

ferredoxin reductase

increases expression

EXP

Ascorbic Acid results in increased expression of FDXR mRNA

NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542

G

fibrinogen beta chain

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434

G

fibroblast growth factor 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 7

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA

NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328

G

fibrinogen gamma chain

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

fibronectin leucine rich transmembrane protein 3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA

NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650

G

Fms related receptor tyrosine kinase 1

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of FLT1 mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA

PMID:21919647 PMID:34480604

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 4

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of FLT4 mRNA]

NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645

G

flavin containing dimethylaniline monoxygenase 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO1 mRNA

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

flavin containing dimethylaniline monoxygenase 5

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO5 mRNA

NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464

G

fragile X messenger ribonucleoprotein 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]

NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675

G

fibronectin 1

multiple interactions

ISO

[Ascorbic Acid co-treated with Quartz] results in increased expression of FN1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of FN1 mRNA

PMID:16443354 PMID:27381660

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

fructosamine-3-kinase-related protein

increases expression

ISO

Ascorbic Acid results in increased expression of FN3KRP mRNA

NCBI chr10:107,186,695...107,195,419

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Ascorbic Acid results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

forkhead box A2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein]

NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757

G

forkhead box D3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA

NCBI chr 5:119,450,532...119,452,898
Ensembl chr 5:119,450,394...119,452,786

G

forkhead box G1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA

NCBI chr 6:72,401,582...72,404,392
Ensembl chr 6:72,394,239...72,427,392

G

forkhead box J1

multiple interactions
increases expression

ISO
EXP

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of FOXJ1 mRNA
Ascorbic Acid results in increased expression of FOXJ1 mRNA

PMID:15372504 PMID:16443354

NCBI chr10:102,065,163...102,069,945
Ensembl chr10:102,065,170...102,069,241

G

forkhead box M1

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA

NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172

G

forkhead box O3

multiple interactions
increases expression
affects localization

ISO

Ascorbic Acid results in increased expression of and results in decreased phosphorylation of FOXO3 protein; FOXO3 protein affects the reaction [Ascorbic Acid results in decreased expression of PCSK9 protein]; FOXO3 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR protein]
Ascorbic Acid results in increased expression of FOXO3 mRNA
Ascorbic Acid affects the localization of FOXO3 protein

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

follicle stimulating hormone subunit beta

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of FSHB protein]

PMID:16248992 PMID:17280759 PMID:18602937 PMID:23470461

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

follicle stimulating hormone receptor

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein]

PMID:18602937 PMID:23470461

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288

G

ferritin heavy chain 1

increases expression

EXP

Ascorbic Acid results in increased expression of FTH1 mRNA

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214

G

ferritin light chain 1

affects expression

ISO

Ascorbic Acid affects the expression of FTL protein

NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915

G

FYN proto-oncogene, Src family tyrosine kinase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein]

NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479

G

frizzled class receptor 10

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA

NCBI chr12:33,734,364...33,737,559
Ensembl chr12:33,734,364...33,741,646

G

frizzled class receptor 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of FZD2 mRNA

NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396

G

G0/G1switch 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of G0S2 mRNA

NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293

G

glucose-6-phosphate dehydrogenase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

GABA type A receptor-associated protein

increases expression

ISO

Ascorbic Acid results in increased expression of GABARAP mRNA

NCBI chr10:55,213,465...55,216,787
Ensembl chr10:55,212,075...55,216,154

G

GA binding protein transcription factor subunit alpha

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of GABPA mRNA]

NCBI chr11:37,375,040...37,404,060
Ensembl chr11:37,375,084...37,404,059

G

gamma-aminobutyric acid type A receptor subunit alpha 2

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA

NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,450,683...37,587,457

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, beta

multiple interactions

EXP

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

cyclin G associated kinase

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of GAK mRNA

NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974

G

galanin and GMAP prepropeptide

multiple interactions

EXP

[ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]

NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229

G

guanidinoacetate N-methyltransferase

affects expression

ISO

Ascorbic Acid affects the expression of GAMT protein

NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression
multiple interactions
decreases expression

ISO

Ascorbic Acid results in increased expression of GAPDH protein
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of GAPDH protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of GAPDH mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of GAPDH mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of GAPDH protein]
Ascorbic Acid results in decreased expression of GAPDH mRNA; Ascorbic Acid results in decreased expression of GAPDH protein

PMID:22139585 PMID:38160894

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377

G

glycyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of GARS1 mRNA

NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876

G

growth arrest specific 7

increases expression

ISO

Ascorbic Acid results in increased expression of GAS7 mRNA

NCBI chr10:52,651,690...52,882,244
Ensembl chr10:52,651,690...52,882,244

G

GATA binding protein 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of GATA1 mRNA

NCBI chr X:17,193,291...17,209,462
Ensembl chr X:17,201,633...17,209,459

G

GATA binding protein 4

increases expression

ISO

Ascorbic Acid results in increased expression of GATA4 mRNA

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609

G

GATA binding protein 6

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA

NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322

G

guanylate binding protein 2

increases expression

EXP

Ascorbic Acid results in increased expression of GBP2 mRNA

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810

G

glucokinase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of GCK mRNA]

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

EXP

[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]]

PMID:27028516 PMID:31585129

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

growth differentiation factor 10

multiple interactions

EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of GDF10 mRNA

NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,243,317...9,256,794

G

glial cell derived neurotrophic factor

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

glial fibrillary acidic protein

decreases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in decreased expression of GFAP protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GFAP protein]
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA

PMID:15372504 PMID:33713149 PMID:34286406

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

GDNF family receptor alpha 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of GFRA1 mRNA

NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501

G

gamma-glutamyltransferase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GGT1 protein]

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050

G

growth hormone 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GH1 protein]

NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859

G

gap junction protein, alpha 1

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of GJA1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein]
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 protein]

PMID:29940330 PMID:34286406

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689

G

GLI family zinc finger 1

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA

NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540

G

glyoxalase 1

affects expression

ISO

Ascorbic Acid affects the expression of GLO1 protein

NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191

G

glyoxalase domain containing 4

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in decreased expression of GLOD4 mRNA]

NCBI chr10:61,575,770...61,594,111

G

glutaredoxin

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GLRX mRNA]

NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543

G

glutaminase

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of GLS mRNA

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861

G

G protein subunit gamma 3

increases expression

ISO

Ascorbic Acid results in increased expression of GNG3 mRNA

NCBI chr 1:215,160,952...215,162,718
Ensembl chr 1:215,160,952...215,162,718

G

G protein subunit gamma 4

increases expression

ISO

Ascorbic Acid results in increased expression of GNG4 mRNA

NCBI chr17:93,432,791...93,481,709
Ensembl chr17:93,433,195...93,481,709

G

G protein subunit gamma 5, pseudogene 3

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of GNG5-PS3 mRNA]

NCBI chr 1:86,420,149...86,420,633
Ensembl chr13:68,738,471...68,738,677

G

glutamic-oxaloacetic transaminase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in increased activity of GOT1 protein]

PMID:30676168 PMID:30738991

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycerol-3-phosphate acyltransferase 3

increases expression

ISO

Ascorbic Acid results in increased expression of GPAT3 mRNA

NCBI chr14:9,018,762...9,072,552

G

glypican 1

multiple interactions
increases expression
increases degradation

ISO

[Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form; Zinc promotes the reaction [[Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form]
Ascorbic Acid results in increased expression of GPC1 mRNA
Ascorbic Acid results in increased degradation of GPC1 protein

PMID:15677459 PMID:21642435 PMID:25555879

NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933

G

glypican 3

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]

NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639

G

glycerol-3-phosphate dehydrogenase 1

multiple interactions

EXP

[Ascorbic Acid co-treated with INS1 protein] results in decreased expression of GPD1 mRNA

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368

G

glucose-6-phosphate isomerase

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of GPI mRNA]

NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261

G

GPN-loop GTPase 1

multiple interactions
decreases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of GPN1 mRNA
Ascorbic Acid results in decreased expression of GPN1 mRNA

NCBI chr 6:30,667,337...30,685,011
Ensembl chr 6:30,666,868...30,685,011

G

G protein-coupled receptor 183

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA

NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977

G

G protein-coupled receptor 55

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of GPR55 protein]

NCBI chr 9:94,037,748...94,081,426
Ensembl chr 9:94,036,162...94,088,707

G

glutamic--pyruvic transaminase

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Ascorbic Acid inhibits the reaction [Food Additives results in increased activity of GPT protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in increased activity of GPT protein]
Ascorbic Acid inhibits the reaction [Diquat results in increased expression of GPT protein]

PMID:16758767 PMID:19391111 PMID:30676168 PMID:30738991 PMID:33475796

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 1

multiple interactions
increases expression

ISO
EXP

[Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 mRNA; [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GPX1 mRNA]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA]
Ascorbic Acid results in increased expression of GPX1 mRNA
2-aminoethoxydiphenyl borate inhibits the reaction [Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in decreased expression of GPX1 mRNA]]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GPX1 protein]; Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of GPX1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GPX1 protein]; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in decreased expression of GPX1 mRNA]

PMID:15372504 PMID:16248992 PMID:16298753 PMID:17179735 PMID:20530418 More...

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione peroxidase 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA

PMID:16443354 PMID:17639512 PMID:34480604

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione peroxidase 4

increases expression

EXP

Ascorbic Acid results in increased expression of GPX4 mRNA

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629

G

glutamate ionotropic receptor AMPA type subunit 1

increases expression

ISO

Ascorbic Acid results in increased expression of GRIA1 protein

NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309

G

glutamate ionotropic receptor AMPA type subunit 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA

PMID:33713149 PMID:34480604

NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616

G

glutamate ionotropic receptor AMPA type subunit 3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA

NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679

G

glutamate ionotropic receptor NMDA type subunit 1

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA

NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754

G

glutamate ionotropic receptor NMDA type subunit 2A

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA

NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378

G

glutamate ionotropic receptor NMDA type subunit 2B

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA

NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570

G

granulin precursor

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of GRN mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of GRN mRNA

NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936

G

gasdermin A

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of GSDMA mRNA]

NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804

G

glycogen synthase kinase 3 beta

decreases expression
multiple interactions

EXP

Ascorbic Acid results in decreased expression of GSK3B mRNA
Ascorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein]

PMID:15372504 PMID:24675465

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249

G

glutathione-disulfide reductase

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with GSR protein] affects the metabolism of Glucose; [juglone co-treated with Ascorbic Acid] results in decreased activity of GSR protein; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased activity of GSR protein]
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in decreased expression of GSR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSR mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of GSR protein]
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of GSR mRNA; Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of GSR protein]

PMID:1901343 PMID:12767684 PMID:16248992 PMID:16298753 PMID:17917374 More...

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase alpha 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GSTA1 mRNA

PMID:17639512 PMID:34480604

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528

G

glutathione S-transferase alpha 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA
Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA]

PMID:16517059 PMID:34480604

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 4

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTA4 mRNA]

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase mu 1

affects response to substance
multiple interactions

ISO
EXP

GSTM1 affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]
GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]

PMID:15668500 PMID:19710200 PMID:23470461

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

multiple interactions
increases expression

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM2 mRNA]
Ascorbic Acid results in increased expression of GSTM2 mRNA

PMID:15372504 PMID:23470461

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase omega 1

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of GSTO1 mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]

PMID:31610155 PMID:34480604

NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167

G

glutathione S-transferase pi 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of GSTP1 protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased methylation of GSTP1 promoter]

PMID:33388378 PMID:34480604

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase theta 1

affects response to substance

ISO

GSTT1 affects the susceptibility to Ascorbic Acid deficiency

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019

G

general transcription factor IIH subunit 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of GTF2H1 mRNA

NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727

G

guanylate cyclase 1 soluble subunit alpha 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA

NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737

G

guanylate cyclase 1 soluble subunit beta 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein]

NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987

G

gulonolactone (L-) oxidase

increases chemical synthesis

EXP

GULO protein results in increased chemical synthesis of Ascorbic Acid

NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422

G

glucuronidase, beta

multiple interactions

EXP

[ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]

NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024

G

granzyme B

decreases expression

ISO

Ascorbic Acid deficiency results in decreased expression of GZMB mRNA

NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469

G

H2A.X variant histone

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX mRNA; [Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation of H2AX protein

PMID:19482829 PMID:26424790

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

H2B clustered histone 14

multiple interactions

ISO

[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of H2BC5 mRNA

NCBI chr17:47,488,627...47,489,008

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

EXP

Ascorbic Acid results in decreased expression of HADHA mRNA

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

heart and neural crest derivatives expressed 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA]
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA

PMID:28189605 PMID:34480604

NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488

G

hepatitis A virus cellular receptor 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA

NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268

G

host cell factor C1

multiple interactions
increases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of HCFC1 mRNA
Ascorbic Acid results in increased expression of HCFC1 mRNA

NCBI chr X:156,839,100...156,864,132
Ensembl chr X:156,839,100...156,863,813

G

helicase, lymphoid specific

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HELLS mRNA

NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228

G

hephaestin

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of HEPH mRNA

NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453

G

homocysteine inducible ER protein with ubiquitin like domain 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of HERPUD1 mRNA

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081

G

hes family bHLH transcription factor 1

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HES1 protein]

NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061

G

hes family bHLH transcription factor 3

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA

NCBI chr 5:168,076,337...168,082,270
Ensembl chr 5:168,077,093...168,078,987

G

hes family bHLH transcription factor 5

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA

NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021

G

hepatocyte growth factor

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

hypoxia inducible factor 1 subunit alpha

increases degradation
multiple interactions

ISO
EXP

Ascorbic Acid results in increased degradation of HIF1A protein
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased hydroxylation of HIF1A protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Quercetin results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in increased stability of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]

PMID:16288478 PMID:17364964 PMID:17382205 PMID:19074761 PMID:19263519 More...

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

hexokinase 1

multiple interactions
decreases expression

ISO

[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of HK1 protein; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of HK1 mRNA; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of HK1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of HK1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of HK1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of HK1 protein]
Ascorbic Acid results in decreased expression of HK1 mRNA; Ascorbic Acid results in decreased expression of HK1 protein

PMID:16443354 PMID:38160894

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

holocarboxylase synthetase

decreases activity

ISO

Ascorbic Acid results in decreased activity of HLCS protein

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

high mobility group box 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB1 mRNA

NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327

G

high mobility group box 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

ISO

Ascorbic Acid results in increased expression of HMGCR mRNA

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

ISO

Ascorbic Acid results in increased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242

G

heme oxygenase 1

increases expression
multiple interactions

ISO
EXP

Ascorbic Acid results in increased expression of HMOX1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]
Ascorbic Acid results in increased expression of HMOX1 mRNA; Ascorbic Acid results in increased expression of HMOX1 protein
[Buthionine Sulfoximine co-treated with Ascorbic Acid] promotes the reaction [Copper Sulfate results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [Cadmium results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [HMOX1 protein results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 protein]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 mRNA]
Ascorbic Acid inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Cadmium results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [Nelfinavir results in increased expression of HMOX1]; Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]

PMID:8743975 PMID:10942521 PMID:15577407 PMID:16171798 PMID:16517059 More...

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

hepatocyte nuclear factor 4, alpha

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of HNF4A mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of HNF4A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased methylation of HNF4A gene]

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758

G

heterogeneous nuclear ribonucleoprotein C

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of HNRNPCL1 mRNA]

NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715

G

homeobox A2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Valproic Acid results in decreased expression of HOXA2 mRNA]
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA

PMID:19655241 PMID:34480604

NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:82,593,389...82,595,692

G

homeo box B1

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA

NCBI chr10:81,827,915...81,830,404
Ensembl chr10:81,827,915...81,830,404

G

homeo box B3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA

NCBI chr10:81,786,001...81,810,655
Ensembl chr10:81,795,882...81,809,628

G

homeo box D4

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA

NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948

G

homeobox D8

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA

NCBI chr 3:80,015,223...80,017,789
Ensembl chr 3:80,014,735...80,018,765

G

haptoglobin

affects activity
affects response to substance
multiple interactions

ISO

Ascorbic Acid affects the activity of HP protein polymorphism
HP gene polymorphism affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]

PMID:19769483 PMID:20926521

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518

G

hypoxanthine phosphoribosyltransferase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712

G

hydroxysteroid (17-beta) dehydrogenase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B1 mRNA]

NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,510,011...86,512,210

G

hydroxysteroid (17-beta) dehydrogenase 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B2 mRNA]

NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions

EXP

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased expression of HSD17B3 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD17B3 mRNA]

PMID:17280759 PMID:33372294

NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions
increases expression

EXP
ISO

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased expression of HSD3B1 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD3B1 mRNA]
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA
Ascorbic Acid results in increased expression of HSD3B1 mRNA

PMID:17280759 PMID:17901237 PMID:33372294 PMID:34480604

NCBI chr 2:188,858,574...188,864,694

G

heat shock protein 90 alpha family class B member 1

affects expression

ISO

Ascorbic Acid affects the expression of HSP90AB1 protein

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNA

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 5

multiple interactions
decreases expression

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of HSPA5 protein]
Ascorbic Acid results in decreased expression of HSPA5 mRNA

PMID:17353921 PMID:19197388

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 9

decreases expression

ISO

Ascorbic Acid results in decreased expression of HSPA9 mRNA

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398

G

heat shock protein family B (small) member 1

multiple interactions
increases expression

ISO
EXP

[Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPB1 mRNA
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of HSPB1 mRNA]
Ascorbic Acid results in increased expression of HSPB1 mRNA

PMID:15372504 PMID:17639512 PMID:37704839

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family E (Hsp10) member 1

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of HSPE1 mRNA

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

islet amyloid polypeptide

multiple interactions

EXP

IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydrogen Peroxide]; IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydroxyl Radical]

NCBI chr 4:176,968,097...176,975,363
Ensembl chr 4:176,968,097...176,975,363

G

isoleucyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of IARS1 mRNA

NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652

G

integrin-binding sialoprotein

multiple interactions
increases expression

EXP
ISO

[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]]
Ascorbic Acid results in increased expression of IBSP mRNA
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA]

PMID:26492236 PMID:27028516 PMID:28105418

NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299

G

intercellular adhesion molecule 1

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ICAM1 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ICAM1 protein]

PMID:12723939 PMID:23114885 PMID:25305479 PMID:25551565 PMID:35349355 More...

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

immediate early response 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of IER3 mRNA

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377

G

interferon, alpha-inducible protein 27

increases expression

EXP

Ascorbic Acid results in increased expression of IFI27 mRNA

NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781

G

interferon gamma

multiple interactions
decreases expression

ISO
EXP

IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of IFNG mRNA]
Ascorbic Acid results in decreased expression of IFNG protein

PMID:14624943 PMID:19298665 PMID:27020608

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

insulin-like growth factor 1 receptor

increases expression

ISO

Ascorbic Acid results in increased expression of IGF1R protein

NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664

G

insulin-like growth factor binding protein 5

multiple interactions

ISO
EXP

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of IGFBP5 mRNA
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA

PMID:16443354 PMID:23859036

NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390

G

insulin-like growth factor binding protein 7

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620

G

Indian hedgehog signaling molecule

increases expression

ISO

Ascorbic Acid results in increased expression of IHH mRNA

NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203

G

IKAROS family zinc finger 1

multiple interactions
decreases activity

ISO

2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]; 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]

NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574

G

interleukin 10

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; Ascorbic Acid promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
Ascorbic Acid inhibits the reaction [Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]]

PMID:25551565 PMID:27020608

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 1 alpha

multiple interactions

ISO

[Ascorbic Acid co-treated with neohesperidin co-treated with pycnogenols co-treated with Tocopherols co-treated with Hyaluronic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Vehicle Emissions] which results in increased expression of IL1A mRNA]

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

multiple interactions

ISO
EXP

Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]; Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]; IL1B protein results in decreased susceptibility to [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein; Ascorbic Acid inhibits the reaction [Silicon Dioxide analog promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased secretion of IL1B protein]; Ascorbic Acid deficiency promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Ascorbic Acid inhibits the reaction [Sodium Fluoride results in increased expression of IL1B protein]

PMID:15612528 PMID:16529823 PMID:22728154 PMID:23692848 PMID:24685903 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor type 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579

G

interleukin 4

decreases expression

ISO

Ascorbic Acid results in decreased expression of IL4 protein

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

interleukin 6

multiple interactions

EXP
ISO

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]; [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased secretion of IL6 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL6 protein]; Ascorbic Acid inhibits the reaction [Sodium Fluoride results in increased expression of IL6 protein]
[Acetylcysteine co-treated with Ascorbic Acid] inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; [Ascorbic Acid co-treated with neohesperidin co-treated with pycnogenols co-treated with Tocopherols co-treated with Hyaluronic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Vehicle Emissions] which results in increased expression of IL6 mRNA]; Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased secretion of IL6 protein]

PMID:22728154 PMID:27020608 PMID:32810504 PMID:34089294 PMID:35150043 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

inhibin subunit beta A

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

inhibin subunit beta E

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA

NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519

G

insulin 1

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA
[Ascorbic Acid co-treated with INS1 protein] results in decreased expression of GPD1 mRNA; [Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA; [Ascorbic Acid co-treated with INS1 protein] results in increased expression of NAMPT mRNA; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of INS1 protein]; [INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; [Lutein co-treated with Ascorbic Acid] results in decreased expression of INS1 protein; Ascorbic Acid inhibits the reaction [INS1 protein results in increased secretion of LEP protein]

PMID:12949374 PMID:20400526 PMID:21911000 PMID:25062436

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

insulin 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [T0901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; Trientine inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein]
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]

PMID:23403016 PMID:25932594 PMID:32473317

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805

G

insulin receptor

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of INSR mRNA]

NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803

G

iron responsive element binding protein 2

multiple interactions

ISO

[Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]

NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520

G

insulin receptor substrate 1

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of IRS1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of IRS1 protein]
Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of IRS1 mRNA]

PMID:21911000 PMID:38185084

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538

G

ISL LIM homeobox 1

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of ISL1 mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA

PMID:15305145 PMID:34480604

NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442

G

integrin subunit alpha 4

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ITGA4 mRNA]; [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ITGA4 protein]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of ITGA4 mRNA]

PMID:37704839 PMID:39325335

NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039

G

integrin subunit alpha M

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ITGAM mRNA]; [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of ITGAM protein]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of ITGAM mRNA]

PMID:37704839 PMID:39325335

NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943

G

inositol 1,4,5-trisphosphate receptor, type 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in increased expression of ITPR1 mRNA]

NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504

G

jagged canonical Notch ligand 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872

G

potassium voltage-gated channel subfamily B member 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of KCNB1 mRNA

NCBI chr 3:176,239,285...176,332,408
Ensembl chr 3:176,242,589...176,332,408

G

lysine demethylase 3A

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A mRNA]; Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A protein]

NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370

G

kinase insert domain receptor

decreases expression

ISO

Ascorbic Acid results in decreased expression of KDR mRNA

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192

G

Kelch-like ECH-associated protein 1

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of KEAP1 protein
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 protein]

PMID:28285367 PMID:31610155 PMID:34480604

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042

G

kinase D-interacting substrate 220

decreases expression

EXP

Ascorbic Acid results in decreased expression of KIDINS220 mRNA

NCBI chr 6:47,346,790...47,435,599
Ensembl chr 6:47,346,832...47,431,865

G

kinesin family member 1B

decreases expression

EXP

Ascorbic Acid results in decreased expression of KIF1B mRNA

NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:164,894,763...165,008,841

G

kinesin family member 1C

decreases expression

EXP

Ascorbic Acid results in decreased expression of KIF1C mRNA

NCBI chr10:55,913,010...55,942,220
Ensembl chr10:55,913,093...55,942,220

G

kinesin family member 23

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of KIF23 mRNA

NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856

G

killer cell lectin like receptor K1

decreases expression

ISO

Ascorbic Acid deficiency results in decreased expression of KLRK1 protein

NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:164,767,946...164,778,382

G

lipopolysaccharide binding protein

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of LBP mRNA]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of LBP mRNA]

PMID:37704839 PMID:39325335

NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518

G

LCK proto-oncogene, Src family tyrosine kinase

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LCK protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LCK protein]

PMID:14572611 PMID:34480604

NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267

G

lactate dehydrogenase A

multiple interactions
decreases expression

ISO

[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased secretion of LDHA protein]; [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of LDHA protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of LDHA mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of LDHA protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of LDHA mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of LDHA protein]
Ascorbic Acid results in decreased expression of LDHA mRNA; Ascorbic Acid results in decreased expression of LDHA protein

PMID:26270818 PMID:38160894

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

low density lipoprotein receptor

multiple interactions
increases expression

ISO

Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA]; FOXO3 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR protein]; SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR mRNA]; SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR protein]
Ascorbic Acid affects the reaction [GULO protein affects the expression of LDLR protein]
Ascorbic Acid results in increased expression of LDLR mRNA; Ascorbic Acid results in increased expression of LDLR protein

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675

G

lymphoid enhancer binding factor 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA

PMID:33713149 PMID:34480604

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

leptin

decreases secretion
multiple interactions

EXP

Ascorbic Acid results in decreased secretion of LEP protein
Ascorbic Acid inhibits the reaction [INS1 protein results in increased secretion of LEP protein]

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

galectin 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of LGALS1 mRNA

NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800

G

galectin 3

increases expression

EXP

Ascorbic Acid results in increased expression of LGALS3 mRNA

NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737

G

luteinizing hormone subunit beta

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein]

PMID:16248992 PMID:16298753 PMID:17280759

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of LHCGR mRNA]

NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061

G

lysyl oxidase-like 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of LOXL2 mRNA

NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842

G

lysophosphatidic acid receptor 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased methylation of LPAR2 promoter]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of LPAR2 mRNA]

NCBI chr16:19,625,974...19,633,905
Ensembl chr16:19,625,983...19,633,905

G

lumican

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA

NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508

G

latexin

increases expression

ISO

Ascorbic Acid results in increased expression of LXN mRNA; Ascorbic Acid results in increased expression of LXN protein

NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488

G

LYN proto-oncogene, Src family tyrosine kinase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LYN protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LYN protein]

NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:21,437,084...21,554,461

G

MAF bZIP transcription factor F

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

MAF bZIP transcription factor G

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA

NCBI chr10:106,401,633...106,410,159

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

increases expression

ISO

Ascorbic Acid results in increased expression of MAGI2 mRNA

NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199

G

MALT1 paracaspase

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MALT1 mRNA

NCBI chr18:61,212,290...61,266,272
Ensembl chr18:61,212,317...61,266,272

G

mannosidase, alpha, class 1A, member 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of MAN1A1 mRNA]

NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584

G

microtubule-associated protein 2

decreases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in decreased expression of MAP2 protein
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein

PMID:15372504 PMID:33713149

NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459

G

mitogen activated protein kinase kinase 3

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K3 protein]

NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004

G

mitogen-activated protein kinase kinase 6

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K6 protein]

NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721

G

mitogen-activated protein kinase kinase kinase 5

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein]

NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

ISO
EXP

U 0126 inhibits the reaction [Ascorbic Acid results in increased phosphorylation of MAPK1 protein]
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased phosphorylation of MAPK1 protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased phosphorylation of MAPK1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of MAPK1 protein modified form]
[juglone co-treated with Ascorbic Acid] results in decreased phosphorylation of MAPK1 protein

PMID:20530736 PMID:21262251 PMID:22728154 PMID:29992683 PMID:31585129 More...

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 14

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

ISO
EXP

U 0126 inhibits the reaction [Ascorbic Acid results in increased phosphorylation of MAPK3 protein]
[juglone co-treated with Ascorbic Acid] results in decreased phosphorylation of MAPK3 protein
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased phosphorylation of MAPK3 protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased phosphorylation of MAPK3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of MAPK3 protein modified form]

PMID:20530736 PMID:21262251 PMID:22728154 PMID:29992683 PMID:31585129 More...

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

multiple interactions

ISO

[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein; Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]

PMID:20206247 PMID:24488945

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 9

multiple interactions

ISO

[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein; Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein]

PMID:20206247 PMID:24488945

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228

G

microtubule-associated protein tau

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]

NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108

G

minichromosome maintenance complex component 4

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNA

NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536

G

midkine

increases expression

EXP

Ascorbic Acid results in increased expression of MDK mRNA

NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743

G

MDM2 proto-oncogene

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein]

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

meprin A subunit alpha

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of MEP1A mRNA

NCBI chr 9:24,971,901...25,001,414
Ensembl chr 9:24,971,886...25,001,414

G

MET proto-oncogene, receptor tyrosine kinase

decreases expression

ISO

Ascorbic Acid results in decreased expression of MET mRNA

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

mitofusin 1

multiple interactions

EXP

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased expression of MFN1 mRNA]

NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190

G

mitofusin 2

multiple interactions

EXP

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased expression of MFN2 mRNA]

NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA]

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482

G

microsomal glutathione S-transferase 1

increases expression

EXP

Ascorbic Acid results in increased expression of MGST1 mRNA

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

microRNA 93

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [Estradiol results in increased expression of MIR93 mRNA]

NCBI chr12:22,156,844...22,156,930

G

marker of proliferation Ki-67

multiple interactions
decreases expression

ISO
EXP

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MKI67 mRNA; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of MKI67 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of MKI67 protein]
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA

PMID:17639512 PMID:23859036 PMID:38160894

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

mutL homolog 1

multiple interactions

ISO

Ascorbic Acid promotes the reaction [MLH1 gene mutant form results in decreased susceptibility to chromium hexavalent ion]; MLH1 protein promotes the reaction [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion]; MLH1 protein results in increased susceptibility to [chromium hexavalent ion co-treated with Ascorbic Acid]

PMID:15831465 PMID:17169990 PMID:17301063

NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011

G

muscular LMNA-interacting protein

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA

NCBI chr 8:86,815,491...87,085,117
Ensembl chr 8:86,814,798...87,082,408

G

membrane metallo-endopeptidase

decreases activity

EXP

Ascorbic acid decreases activity of Mme protein in osteoblasts

RGD

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463

G

matrix metallopeptidase 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; Ascorbic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]

PMID:10836612 PMID:34480604

NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964

G

matrix metallopeptidase 13

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]

PMID:23692848 PMID:26526931

NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105

G

matrix metallopeptidase 2

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of MMP2 protein]
[juglone co-treated with Ascorbic Acid] affects the expression of MMP2 mRNA

PMID:19391111 PMID:29992683

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 7

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MMP7 mRNA

NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755

G

matrix metallopeptidase 9

multiple interactions

ISO
EXP

[juglone co-treated with Ascorbic Acid] results in decreased expression of MMP9 mRNA
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of MMP9 mRNA]; [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of MMP9 protein]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of MMP9 mRNA]

PMID:29992683 PMID:37704839 PMID:39325335

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

MOB kinase activator 3B

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of MOB3B mRNA]

NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:54,338,056...54,454,678

G

myeloperoxidase

multiple interactions

EXP
ISO

[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein]; Ascorbic Acid inhibits the reaction [Fluorouracil results in increased activity of MPO protein]; Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]

PMID:18726076 PMID:19462961 PMID:26921358 PMID:27020608 PMID:31022331

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

myelin protein zero-like 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA

NCBI chr13:80,385,454...80,422,315
Ensembl chr13:80,385,456...80,422,390

G

mutS homolog 2

multiple interactions

ISO

MSH2 protein promotes the reaction [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion]; MSH2 protein results in increased susceptibility to [chromium hexavalent ion co-treated with Ascorbic Acid]

PMID:17169990 PMID:17301063

NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503

G

macrophage stimulating 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of MST1 mRNA

NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015

G

msh homeobox 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA]

NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945

G

metallothionein 1A

increases expression

EXP

Ascorbic Acid results in increased expression of MT1A mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 3

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of MT3 mRNA
[[MT3 protein binds to Zinc] which co-treated with Ascorbic Acid] inhibits the reaction [Copper results in increased chemical synthesis of Hydroxyl Radical]

PMID:15372504 PMID:17389590

NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

decreases expression

ISO

Ascorbic Acid results in decreased expression of MTHFD2 mRNA

NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350

G

major vault protein

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of MVP mRNA]

NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873

G

MYB proto-oncogene, transcription factor

multiple interactions

EXP

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MYB protein

NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:17,759,309...17,792,547

G

MYB proto-oncogene like 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of MYBL2 mRNA

NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA]

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

myosin heavy chain 11

increases expression

EXP

Ascorbic Acid results in increased expression of MYH11 protein

NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678

G

myosin heavy chain 6

increases expression

ISO

Ascorbic Acid results in increased expression of MYH6 mRNA

NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333

G

myosin heavy chain 7

increases expression

ISO

Ascorbic Acid results in increased expression of MYH7 mRNA

PMID:12668514 PMID:21570463

NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194

G

myosin light chain 2

increases expression

ISO

Ascorbic Acid results in increased expression of MYL2 mRNA

NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149

G

myosin, light chain 4

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA

NCBI chr10:89,949,733...89,985,308
Ensembl chr10:89,949,404...89,985,308

G

myosin IA

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of MYO1A mRNA

NCBI chr 7:65,424,206...65,443,227
Ensembl chr 7:65,428,258...65,443,213

G

myosin IE

decreases expression

EXP

Ascorbic Acid results in decreased expression of MYO1E mRNA

NCBI chr 8:79,768,828...79,961,048
Ensembl chr 8:79,753,596...79,961,045

G

nicotinamide phosphoribosyltransferase

multiple interactions

EXP

[Ascorbic Acid co-treated with INS1 protein] results in increased expression of NAMPT mRNA

NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544

G

asparaginyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of NARS1 mRNA

NCBI chr18:60,259,506...60,275,782
Ensembl chr18:60,259,516...60,275,782

G

neurocalcin delta

increases expression

ISO

Ascorbic Acid results in increased expression of NCALD mRNA

NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482

G

N-myc downstream regulated 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of NDRG1 protein]

NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913

G

NDRG family member 2

increases expression

EXP

Ascorbic Acid results in increased expression of NDRG2 mRNA

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

nestin

decreases expression

EXP

Ascorbic Acid results in decreased expression of NES protein

NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228

G

NFE2 like bZIP transcription factor 1

increases expression

ISO

Ascorbic Acid results in increased expression of NFE2L1 mRNA; Ascorbic Acid results in increased expression of NFE2L1 protein

NCBI chr10:82,296,824...82,309,472
Ensembl chr10:82,292,508...82,309,375

G

NFE2 like bZIP transcription factor 2

multiple interactions
increases expression
affects localization

ISO
EXP

[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] promotes the reaction [[Ozone co-treated with Oxygen] results in increased localization of NFE2L2 protein]; [lead acetate results in increased abundance of Lead] inhibits the reaction [Ascorbic Acid results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased activity of NFE2L2 promoter]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA]
Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 protein]
Ascorbic Acid results in increased expression of NFE2L2 mRNA; Ascorbic Acid results in increased expression of NFE2L2 protein
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol affects the localization of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 protein]; Ascorbic Acid promotes the reaction [Cadmium results in increased expression of NFE2L2 protein]; Ascorbic Acid promotes the reaction [Fluorouracil affects the localization of NFE2L2 protein]
Ascorbic Acid affects the localization of NFE2L2 protein

PMID:21199573 PMID:22008531 PMID:23027624 PMID:23492819 PMID:25130429 More...

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NFE2 like bZIP transcription factor 3

decreases expression

ISO

Ascorbic Acid results in decreased expression of NFE2L3 mRNA; Ascorbic Acid results in decreased expression of NFE2L3 protein

NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532

G

nuclear factor I/B

increases expression

ISO

Ascorbic Acid results in increased expression of NFIB mRNA

NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945

G

nuclear factor kappa B subunit 1

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]
Ascorbic Acid inhibits the reaction [Fluorouracil affects the localization of NFKB1 protein]

PMID:17879260 PMID:23114885 PMID:23692848 PMID:26921358

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased degradation of NFKBIA protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]

PMID:17879260 PMID:25305479 PMID:25551565

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nuclear transcription factor Y subunit alpha

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NFYA mRNA

NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504

G

ninjurin 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNA

NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,659,200...15,668,063

G

NK2 homeobox 1

multiple interactions

ISO
EXP

Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of NKX2-1 mRNA]; Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of NKX2-1 protein]

PMID:15083329 PMID:16863852

NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:79,731,677...79,736,441

G

NK2 homeobox 5

increases expression

ISO

Ascorbic Acid results in increased expression of NKX2-5 mRNA

NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452

G

NME/NM23 nucleoside diphosphate kinase 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NME1 mRNA

NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310

G

neuronatin

increases expression

ISO

Ascorbic Acid results in increased expression of NNAT mRNA

NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086

G

noggin

multiple interactions

EXP

NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]

NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103

G

nitric oxide synthase 2

increases activity
multiple interactions
decreases expression

ISO
EXP

Ascorbic Acid results in increased activity of NOS2 protein
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]
Ascorbic Acid results in decreased expression of NOS2
[Ascorbic Acid co-treated with Formaldehyde] results in decreased expression of NOS2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [endotoxin, Escherichia coli results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased activity of NOS2 protein]
Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of NOS2 protein]

PMID:15612528 PMID:17218764 PMID:17637181 PMID:18779489 PMID:19391111 More...

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

nitric oxide synthase 3

multiple interactions
increases activity
increases phosphorylation

ISO
EXP

[Isosorbide Dinitrate co-treated with Ascorbic Acid] affects the expression of NOS3 mRNA
Ascorbic Acid results in increased activity of NOS3 protein
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dexamethasone results in decreased expression of NOS3 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde results in decreased expression of NOS3 mRNA]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of NOS3 protein]
Ascorbic Acid results in increased phosphorylation of NOS3 protein

PMID:11243424 PMID:11729227 PMID:15719745 PMID:20068362 PMID:21570463 More...

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

NADPH oxidase 1

increases expression

ISO

Ascorbic Acid results in increased expression of NOX1 protein

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520

G

NADPH oxidase 4

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of NOX4 mRNA; Ascorbic Acid results in increased expression of NOX4 protein
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of NOX4 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of NOX4 protein]

PMID:21570463 PMID:25305479

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483

G

nucleophosmin 1

increases expression

ISO

Ascorbic Acid results in increased expression of NPM1 mRNA

NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr X:18,245,740...18,256,024

G

NAD(P)H quinone dehydrogenase 1

multiple interactions
increases expression

ISO
EXP

Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 protein]; Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of NQO1 mRNA]
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NQO1 protein]
Ascorbic Acid results in increased expression of NQO1 protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Ascorbic Acid promotes the reaction [Cadmium results in increased expression of NQO1 protein]

PMID:16517059 PMID:22008531 PMID:25130429 PMID:29663635 PMID:31610155 More...

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]

NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532

G

nuclear receptor subfamily 2, group F, member 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA

NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:9,776,179...9,785,924

G

nuclear receptor subfamily 2, group F, member 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA

NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:133,420,227...133,431,975

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR3C1 mRNA

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843

G

nuclear receptor subfamily 4, group A, member 2

increases expression
multiple interactions

EXP

Ascorbic Acid results in increased expression of NR4A2 protein
[Ascorbic Acid co-treated with Vitamin E] results in increased expression of NR4A2 protein

NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769

G

nuclear receptor subfamily 4, group A, member 3

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR4A3 mRNA

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285

G

nuclear receptor subfamily 5, group A, member 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of NR5A1 mRNA]

NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046

G

neuronal regeneration related protein

increases expression

ISO

Ascorbic Acid results in increased expression of NREP mRNA

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742

G

neurexin 1

decreases expression

EXP

Ascorbic Acid results in decreased expression of NRXN1 mRNA

NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:8,935,523...10,077,374

G

nuclear receptor binding SET domain protein 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of NSD2 mRNA

NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027

G

neurotrophic receptor tyrosine kinase 2

increases expression

ISO

Ascorbic Acid results in increased expression of NTRK2 mRNA

NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628

G

occludin

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of OCLN protein]

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

oxoglutarate dehydrogenase

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of OGDH protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of OGDH protein]

PMID:12915223 PMID:24295472

NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271

G

2-oxoglutarate and iron-dependent oxygenase domain containing 1

multiple interactions
decreases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of OGFOD1 mRNA
Ascorbic Acid results in decreased expression of OGFOD1 mRNA

NCBI chr19:10,950,950...10,980,519
Ensembl chr19:10,950,060...10,980,519

G

8-oxoguanine DNA glycosylase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of OGG1 protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased methylation of OGG1 promoter]

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604

G

oligodendrocyte transcription factor 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA

NCBI chr11:43,961,585...43,964,961
Ensembl chr11:43,958,940...43,968,634

G

oxidized low density lipoprotein receptor 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA

NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598

G

OS9, endoplasmic reticulum lectin

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of OS9 mRNA

NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070

G

orthodenticle homeobox 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA

NCBI chr15:24,422,876...24,432,709
Ensembl chr15:24,422,876...24,432,472

G

prolyl 4-hydroxylase subunit alpha 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of P4HA2 mRNA

NCBI chr10:38,743,894...38,772,741
Ensembl chr10:38,743,894...38,772,993

G

prolyl 4-hydroxylase, transmembrane

multiple interactions

ISO

[Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] results in increased activity of P4HTM protein

NCBI chr 8:118,153,158...118,172,199
Ensembl chr 8:118,153,158...118,171,002

G

peptidyl arginine deiminase 4

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of PADI4 mRNA]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of PADI4 mRNA]

PMID:37704839 PMID:39325335

NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:158,324,417...158,360,422

G

3'-phosphoadenosine 5'-phosphosulfate synthase 1

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of PAPSS1 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of PAPSS1 mRNA

NCBI chr 2:222,646,103...222,788,475
Ensembl chr 2:222,714,487...222,788,670

G

poly (ADP-ribose) polymerase 1

multiple interactions

EXP
ISO

Ascorbic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of PARP1 protein]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA]
[juglone co-treated with Ascorbic Acid] results in increased degradation of PARP1 protein; Ascorbic Acid inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of PARP1 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]

PMID:16407847 PMID:17301063 PMID:19433269 PMID:21262251 PMID:22678527 More...

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

protocadherin gamma subfamily A, 12

increases expression

ISO

Ascorbic Acid results in increased expression of PCDHGA12 mRNA

NCBI chr18:29,843,897...29,919,095

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

decreases expression

ISO

Ascorbic Acid results in decreased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864

G

proliferating cell nuclear antigen

multiple interactions

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of PCNA protein
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of PCNA protein; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of PCNA protein]

PMID:17917374 PMID:18544905 PMID:21621607

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

Purkinje cell protein 4

increases expression

EXP

Ascorbic Acid results in increased expression of PCP4 mRNA

NCBI chr11:49,229,185...49,331,186
Ensembl chr11:49,270,186...49,331,186

G

proprotein convertase subtilisin/kexin type 9

multiple interactions
decreases expression

ISO

FOXO3 protein affects the reaction [Ascorbic Acid results in decreased expression of PCSK9 protein]
Ascorbic Acid affects the reaction [GULO protein affects the expression of PCSK9 protein]; Ascorbic Acid results in decreased expression of and results in decreased secretion of PCSK9 protein
Ascorbic Acid results in decreased expression of PCSK9 mRNA; Ascorbic Acid results in decreased expression of PCSK9 protein

NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507

G

phosphodiesterase 1A

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA

NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212

G

platelet derived growth factor receptor beta

multiple interactions

EXP

[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

protein disulfide isomerase family A, member 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of PDIA2 mRNA

NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396

G

protein disulfide isomerase family A, member 3

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PDIA3 mRNA]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PDIA3 protein]

NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327

G

phosphatidylethanolamine binding protein 1

increases expression

ISO

Ascorbic Acid results in increased expression of PEBP1 mRNA; Ascorbic Acid results in increased expression of PEBP1 protein

NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780

G

peptidase D

increases activity

ISO

Ascorbic Acid results in increased activity of PEPD protein

NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190

G

phosphoribosylformylglycinamidine synthase

multiple interactions
increases expression

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of PFAS mRNA
Ascorbic Acid results in increased expression of PFAS mRNA

NCBI chr10:54,189,157...54,210,685
Ensembl chr10:54,189,157...54,207,272

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Iodoacetamide affects the activity of PFKFB1 protein]

NCBI chr X:22,936,038...22,989,691
Ensembl chr X:22,937,494...22,989,704

G

phosphofructokinase, muscle

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of PFKM mRNA; Ascorbic Acid results in decreased expression of PFKM protein
[arsenic trichloride co-treated with Ascorbic Acid] results in decreased expression of PFKM mRNA; [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PFKM protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PFKM mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PFKM protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PFKM mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PFKM protein]

NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248

G

phosphoglycerate mutase 1

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of PGAM1 mRNA]

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203

G

phosphoglycerate kinase 1

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of PGK1 mRNA; Ascorbic Acid results in decreased expression of PGK1 protein
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PGK1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGK1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGK1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGK1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGK1 protein]

NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959

G

phosphoglucomutase 1

multiple interactions
decreases expression

ISO

[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PGM1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGM1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGM1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGM1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGM1 protein]
Ascorbic Acid results in decreased expression of PGM1 mRNA; Ascorbic Acid results in decreased expression of PGM1 protein

NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159

G

PHD finger protein 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PHF2 mRNA

NCBI chr17:15,989,594...16,057,583
Ensembl chr17:15,981,604...16,057,583

G

phosphoglycerate dehydrogenase

decreases expression

ISO

Ascorbic Acid results in decreased expression of PHGDH mRNA

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789

G

pleckstrin homology-like domain, family A, member 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA1 mRNA

NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542

G

pleckstrin homology-like domain, family A, member 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA2 mRNA

NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

EXP

Ascorbic Acid results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

pyruvate kinase M1/2

increases expression
affects expression
decreases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of PKM mRNA
Ascorbic Acid affects the expression of PKM protein
Ascorbic Acid results in decreased expression of PKM mRNA; Ascorbic Acid results in decreased expression of PKM protein
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PKM protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PKM mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PKM protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PKM mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PKM protein]

PMID:22139585 PMID:38160894

NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396

G

phospholipase A and acyltransferase 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of PLAAT3 mRNA

NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763

G

plasminogen activator, tissue type

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Endosulfan results in increased activity of PLAT protein]; Ascorbic Acid promotes the reaction [Vitamin E results in increased activity of PLAT protein]

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696

G

plasminogen

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Arsenic promotes the reaction [Humic Substances results in decreased activity of PLG protein]]; Ascorbic Acid inhibits the reaction [Humic Substances results in decreased activity of PLG protein]

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

perilipin 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]

PMID:25932594 PMID:32473317

NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206

G

polo-like kinase 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637

G

polo-like kinase 2

decreases expression

EXP

Ascorbic Acid results in decreased expression of PLK2 mRNA

NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296

G

phospholamban

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA

NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241

G

plastin 3

increases expression

ISO

Ascorbic Acid results in increased expression of PLS3 mRNA; Ascorbic Acid results in increased expression of PLS3 protein

NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893

G

phorbol-12-myristate-13-acetate-induced protein 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PMAIP1 mRNA]

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382

G

peripheral myelin protein 22

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of PMP22 mRNA
Ascorbic Acid inhibits the reaction [Bucladesine results in increased activity of PMP22 promoter]

PMID:15034573 PMID:17303424

NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940

G

purine nucleoside phosphorylase

affects expression

ISO

Ascorbic Acid affects the expression of PNP protein

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162

G

proopiomelanocortin

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of POMC protein]

NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173

G

paraoxonase 1

multiple interactions
decreases activity

EXP
ISO

[Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein
Ascorbic Acid results in decreased activity of PON1 protein
1,2-dioleoyl-sn-glycero-3-phosphoglycerol inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; 1,2-dioleoyl-sn-glycero-3-phosphoglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; 1,2-dipalmitoylphosphatidylglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; 1,2-oleoylphosphatidylcholine inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; [Ascorbic Acid co-treated with Copper Sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; [Ascorbic Acid co-treated with Copper Sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein; [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with ferrous sulfate] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein; [PON1 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]] which results in increased chemical synthesis of 5,6,7,8-tetrahydroxy-4-oxooctanal; Butylated Hydroxytoluene inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]; erucic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; PON1 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]; Sulfhydryl Compounds inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]

PMID:12871208 PMID:15104111 PMID:15375178 PMID:16052486 PMID:20353174

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924

G

paraoxonase 2

multiple interactions

ISO

[PON2 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]] which results in increased chemical synthesis of 5,6,7,8-tetrahydroxy-4-oxooctanal; PON2 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]

NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996

G

POU class 5 homeobox 1

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of POU5F1 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of POU5F1 mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; Ascorbic Acid inhibits the reaction [Cobalt results in increased expression of POU5F1 protein]

PMID:21166886 PMID:24497960 PMID:28189605 PMID:34480604

NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598

G

peroxisome proliferator-activated receptor gamma

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]

PMID:14505802 PMID:25932594 PMID:32473317

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

increases expression

ISO

Ascorbic Acid results in increased expression of PPARGC1A mRNA

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

PPARG related coactivator 1

multiple interactions

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA

NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:254,851,164...254,867,570

G

peroxiredoxin 1

multiple interactions

EXP

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX1 mRNA

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

peroxiredoxin 3

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of PRDX3 mRNA]

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300

G

perforin 1

decreases expression

ISO

Ascorbic Acid deficiency results in decreased expression of PRF1 mRNA

NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124

G

protein kinase C, beta

increases expression

ISO

Ascorbic Acid results in increased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740

G

protein kinase C, theta

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of PRKCQ mRNA

NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508

G

prolactin

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of PRL protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of PRL protein]

PMID:16298753 PMID:18602937

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217

G

protein S

decreases expression

EXP

Ascorbic Acid results in decreased expression of PROS1 mRNA

NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852

G

proteasome 20S subunit beta 6

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [epoxomicin results in increased expression of PSMB6 mRNA]; Ascorbic Acid inhibits the reaction [Rotenone results in increased expression of PSMB6 mRNA]

NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,737,888...55,740,218

G

proteasome 26S subunit, ATPase 3

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of PSMC3 mRNA

NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176

G

proteasome activator subunit 2

increases expression

ISO

Ascorbic Acid results in increased expression of PSME2 mRNA; Ascorbic Acid results in increased expression of PSME2 protein

NCBI chr15:33,048,452...33,053,055
Ensembl chr15:33,048,457...33,053,102

G

prostaglandin-endoperoxide synthase 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of PTGS1 mRNA]

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

prostaglandin-endoperoxide synthase 2

multiple interactions

ISO
EXP

[juglone co-treated with Ascorbic Acid] results in decreased expression of PTGS2 mRNA; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]; Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of PTGS2 mRNA]
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of PTGS2 mRNA]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 mRNA; [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [JP8 aviation fuel results in increased expression of PTGS2 mRNA]

PMID:17218764 PMID:17222177 PMID:17637181 PMID:19095747 PMID:21873648 More...

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

parathyroid hormone 1 receptor

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA]

NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108

G

parathyroid hormone-like hormone

decreases expression

EXP

Ascorbic Acid results in decreased expression of PTHLH mRNA

NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454

G

protein tyrosine kinase 2

decreases expression

EXP

Ascorbic Acid results in decreased expression of PTK2 mRNA

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091

G

pleiotrophin

increases expression

ISO

Ascorbic Acid results in increased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

parvalbumin

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of PVALB protein]

NCBI chr 7:111,653,820...111,668,469
Ensembl chr 7:111,653,111...111,668,446

G

RAB3B, member RAS oncogene family

multiple interactions
increases expression

ISO
EXP

[Quercetin co-treated with Ascorbic Acid] results in increased expression of RAB3B mRNA
Ascorbic Acid results in increased expression of RAB3B mRNA

PMID:15372504 PMID:17639512

NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:128,841,716...128,926,086

G

RAB6A, member RAS oncogene family

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of RAB6A mRNA

NCBI chr 1:164,370,033...164,422,324
Ensembl chr 1:164,369,861...164,417,763

G

Rac family small GTPase 1

multiple interactions

ISO

Ascorbic Acid promotes the reaction [arsenic trioxide results in increased activity of RAC1 protein]

NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109

G

RAD50 double strand break repair protein

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of RAD50 mRNA

NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100

G

RAD51 paralog C

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of RAD51C mRNA

NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143

G

RAD54 homolog B

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of RAD54B mRNA

NCBI chr 5:29,829,465...29,901,967
Ensembl chr 5:29,855,304...29,901,964

G

RAN, member RAS oncogene family

increases expression

ISO

Ascorbic Acid results in increased expression of RAN mRNA; Ascorbic Acid results in increased expression of RAN protein

NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317

G

RNA binding fox-1 homolog 3

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein

NCBI chr10:104,218,940...104,655,863
Ensembl chr10:104,218,940...104,551,945

G

RNA binding motif protein 20

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA

NCBI chr 1:262,671,311...262,912,551
Ensembl chr 1:262,688,978...262,891,364

G

regulator of calcineurin 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in increased expression of RCAN1 mRNA

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236

G

REL proto-oncogene, NF-kB subunit

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of REL protein]

NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]
[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of RELA protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of RELA protein]; Ascorbic Acid inhibits the reaction [lead acetate affects the localization of RELA protein]
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased localization of RELA protein]; [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein]; Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of RELA protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and affects the localization of RELA protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of RELA protein]

PMID:17879260 PMID:19391111 PMID:22728154 PMID:23114885 PMID:23692848 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

regulator of G-protein signaling 8

decreases expression

EXP

Ascorbic Acid results in decreased expression of RGS8 mRNA

NCBI chr13:68,355,078...68,399,412
Ensembl chr13:68,355,157...68,399,412

G

ras homolog family member A

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of RHOA mRNA]

NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302

G

rabphilin 3A

increases expression

ISO

Ascorbic Acid results in increased expression of RPH3A mRNA

NCBI chr12:41,203,004...41,279,536
Ensembl chr12:41,200,089...41,279,531

G

ribosomal protein S29

increases expression

EXP

Ascorbic Acid results in increased expression of RPS29 mRNA

NCBI chr 6:93,371,293...93,372,731
Ensembl chr13:87,816,954...87,817,267
Ensembl chr 6:87,816,954...87,817,267

G

ribosomal protein SA

affects expression

ISO

Ascorbic Acid affects the expression of RPSA protein

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA

NCBI chr19:360,581...363,874
Ensembl chr19:360,973...363,871

G

arginine and serine rich coiled-coil 1

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in decreased expression of RSRC1 mRNA]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of RSRC1 mRNA]

PMID:37704839 PMID:39325335

NCBI chr 2:153,536,839...153,942,825
Ensembl chr 2:153,541,161...153,942,824

G

RUNX family transcription factor 2

multiple interactions
increases expression

ISO
EXP

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA; [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]
Ascorbic Acid results in increased expression of RUNX2 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; [Ascorbic Acid co-treated with Phosphates] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]; Lithium Chloride affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]]; Lithium Chloride affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]]; U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of RUNX2 mRNA]

PMID:17692823 PMID:20530736 PMID:21613385 PMID:26424790 PMID:26492236 More...

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027

G

S100 calcium binding protein A10

increases expression

EXP

Ascorbic Acid results in increased expression of S100A10 mRNA

NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103

G

S100 calcium binding protein A2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]

NCBI chr 2:178,374,659...178,375,903

G

S100 calcium-binding protein A4

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Copper promotes the reaction [S100A4 protein binds to S100A4 protein]]

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837

G

S100 calcium binding protein A6

increases expression

EXP

Ascorbic Acid results in increased expression of S100A6 mRNA

NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762

G

S100 calcium binding protein B

increases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of S100B mRNA
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein

PMID:15372504 PMID:33713149

NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081

G

S100 calcium binding protein G

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of S100G mRNA

NCBI chr X:35,337,636...35,340,205
Ensembl chr X:35,337,675...35,340,205

G

SATB homeobox 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]

NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:65,844,570...66,021,238

G

scavenger receptor class B, member 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA

NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980

G

stearoyl-CoA desaturase

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

sodium voltage-gated channel alpha subunit 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA

PMID:33713149 PMID:34480604

NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:70,710,954...70,845,279

G

syndecan 2

decreases expression

EXP

Ascorbic Acid results in decreased expression of SDC2 mRNA

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294

G

succinate dehydrogenase complex flavoprotein subunit A

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein]

NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121

G

Sec61 translocon subunit gamma

decreases expression

EXP

Ascorbic Acid results in decreased expression of SEC61G mRNA

NCBI chr14:95,113,083...95,119,458
Ensembl chr 9:48,798,504...48,798,710
Ensembl chr14:48,798,504...48,798,710

G

selectin E

multiple interactions

ISO

[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of SELE mRNA]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903

G

selenoprotein I

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of SELENOI mRNA]

NCBI chr 6:31,792,972...31,831,170
Ensembl chr 6:31,792,973...31,831,523

G

semaphorin 3C

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA

NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:18,538,454...18,701,740

G

serpin family A member 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA

NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703

G

serpin family B member 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of SERPINB2 mRNA

NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031

G

serpin family E member 1

multiple interactions

EXP

Ascorbic Acid promotes the reaction [Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein]]

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

sestrin 2

multiple interactions

ISO

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]

NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255

G

secreted frizzled-related protein 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA

NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079

G

surfactant protein B

multiple interactions

ISO
EXP

Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of SFTPB mRNA]; Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of SFTPB protein]

PMID:15083329 PMID:16490937 PMID:16863852

NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646

G

surfactant protein C

decreases expression

EXP

Ascorbic Acid results in decreased expression of SFTPC mRNA

NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475

G

SH3-domain binding protein 5

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA

NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,589,877...6,655,211

G

serine hydroxymethyltransferase 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of SHMT2 mRNA

NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567

G

sucrase-isomaltase

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of SI mRNA

NCBI chr 2:159,804,568...159,884,902
Ensembl chr 2:159,804,568...159,883,934

G

solute carrier family 11 member 2

decreases expression
increases expression

ISO

Ascorbic Acid results in decreased expression of SLC11A2 protein
Ascorbic Acid results in increased expression of SLC11A2 protein

NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941

G

solute carrier family 17 member 6

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA

NCBI chr 1:110,348,447...110,388,499
Ensembl chr 1:110,348,447...110,388,498

G

solute carrier family 17 member 7

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein

NCBI chr 1:104,786,172...104,798,049
Ensembl chr 1:104,785,955...104,798,049

G

solute carrier family 22 member 7

increases transport

ISO

SLC22A7 protein results in increased transport of Ascorbic Acid

NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681

G

solute carrier family 23 member 1

multiple interactions
affects uptake
increases expression
affects transport
affects abundance
decreases expression
increases transport

ISO

Quercetin inhibits the reaction [SLC23A1 protein results in increased transport of Ascorbic Acid]
SLC23A1 protein affects the uptake of Ascorbic Acid
Ascorbic Acid results in increased expression of SLC23A1 mRNA
SLC23A1 protein affects the transport of Ascorbic Acid
SLC23A1 gene polymorphism affects the abundance of Ascorbic Acid
Ascorbic Acid results in decreased expression of SLC23A1 mRNA; Ascorbic Acid results in decreased expression of SLC23A1 protein
Ascorbic Acid deficiency results in increased expression of SLC23A1 mRNA; Ascorbic Acid deficiency results in increased expression of SLC23A1 protein

PMID:11834736 PMID:11984597 PMID:12381735 PMID:20122894 PMID:20471816 More...

NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702

G

solute carrier family 23 member 2

decreases expression
increases abundance
multiple interactions
increases expression

EXP
ISO

Ascorbic Acid results in decreased expression of SLC23A2 mRNA
SLC23A2 mRNA results in increased abundance of Ascorbic Acid
Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased expression of SLC23A2 mRNA]; Diclofenac inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Estradiol inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Genistein inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Hydrocortisone inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Indomethacin inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Progesterone inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Quercetin inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]
Ascorbic Acid deficiency results in increased expression of SLC23A2 protein; Ascorbic Acid results in increased expression of SLC23A2 mRNA

PMID:16288478 PMID:17092984 PMID:19418264 PMID:20122894 PMID:22001929 More...

NCBI chr 3:139,755,583...139,913,304
Ensembl chr 3:139,755,584...139,847,343

G

solute carrier family 2 member 1

increases expression
decreases expression
affects expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of SLC2A1 mRNA
Ascorbic Acid results in decreased expression of SLC2A1 mRNA; Ascorbic Acid results in decreased expression of SLC2A1 protein
Ascorbic Acid affects the expression of SLC2A1 protein
[arsenic trichloride co-treated with Ascorbic Acid] results in decreased expression of SLC2A1 mRNA; [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of SLC2A1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of SLC2A1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of SLC2A1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of SLC2A1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of SLC2A1 protein]

PMID:15372504 PMID:38160894

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742

G

solute carrier family 2 member 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of SLC2A2 mRNA]

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467

G

solute carrier family 2 member 4

increases expression
multiple interactions

ISO
EXP

Ascorbic Acid results in increased expression of SLC2A4 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate affects the localization of SLC2A4 protein]

PMID:20122894 PMID:21911000

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270

G

solute carrier family 46 member 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of SLC46A1 mRNA]

NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869

G

solute carrier family 6 member 1

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SLC6A1 protein]

NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:149,004,635...149,037,839

G

solute carrier family 7 member 11

increases expression

ISO

Ascorbic Acid results in increased expression of SLC7A11 mRNA

NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695

G

solute carrier organic anion transporter family, member 2b1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA

NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279

G

SMAD family member 1

multiple interactions

ISO

[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD1 mRNA]

NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957

G

SMAD family member 2

multiple interactions

ISO

[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in decreased phosphorylation of and affects the localization of SMAD2 protein; Particulate Matter promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in decreased phosphorylation of and affects the localization of SMAD2 protein]

NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388

G

SMAD family member 4

multiple interactions

ISO

[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD4 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Particulate Matter] results in decreased expression of SMAD4 protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMAD4 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD4 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMAD4 protein]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]]; SMAD4 protein promotes the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]]

PMID:26492236 PMID:38914176

NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684

G

SMAD family member 5

multiple interactions

ISO

[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA]

NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992

G

SMAD family member 9

multiple interactions

ISO

[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD9 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD9 mRNA]

NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:141,106,668...141,156,477

G

structural maintenance of chromosomes 6

decreases expression

ISO

Ascorbic Acid results in decreased expression of SMC6 mRNA

NCBI chr 6:39,697,810...39,752,275
Ensembl chr 6:39,697,811...39,752,279

G

SMAD specific E3 ubiquitin protein ligase 1

multiple interactions

ISO

[Particulate Matter co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMURF1 mRNA

NCBI chr12:14,748,717...14,840,273
Ensembl chr12:14,749,043...14,840,273

G

synuclein alpha

increases expression

ISO

Ascorbic Acid results in increased expression of SNCA mRNA

NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315

G

superoxide dismutase 1

multiple interactions
increases expression
affects abundance

ISO
EXP

[Ascorbic Acid co-treated with Vitamin E] results in increased expression of SOD1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of SOD1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SOD1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD1 protein]
Ascorbic Acid results in increased expression of SOD1 mRNA
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of SOD1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 protein]; Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [Lead results in decreased expression of SOD1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of SOD1 mRNA]
SOD1 protein affects the abundance of Ascorbic Acid

PMID:16377630 PMID:16443354 PMID:17822687 PMID:21344382 PMID:22056337 More...

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

increases response to substance
multiple interactions
increases expression

ISO
EXP

SOD2 protein results in increased susceptibility to Ascorbic Acid
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde results in decreased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Lead results in decreased expression of SOD2 protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA]
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [HMOX1 protein results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]
Ascorbic Acid deficiency results in increased expression of SOD2 mRNA; Ascorbic Acid results in increased expression of SOD2 mRNA

PMID:10942521 PMID:15130278 PMID:15612528 PMID:18779489 PMID:19932582 More...

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

superoxide dismutase 3

affects localization
multiple interactions
increases expression
increases activity

EXP
ISO

Ascorbic Acid affects the localization of SOD3 protein
Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of SOD3 protein]
Ascorbic Acid results in increased expression of SOD3 protein
Ascorbic Acid results in increased activity of SOD3 protein
Ascorbic Acid inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased activity of SOD3 protein]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of SOD3 protein]

PMID:23027624 PMID:25130429

NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125

G

sortilin 1

increases expression

ISO

Ascorbic Acid results in increased expression of SORT1 mRNA

NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:198,612,148...198,690,481

G

SRY-box transcription factor 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA

NCBI chr16:83,837,689...83,841,703
Ensembl chr16:83,802,160...83,841,775

G

SRY-box transcription factor 10

increases expression

ISO

Ascorbic Acid results in increased expression of SOX10 mRNA

NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990

G

SRY-box transcription factor 11

decreases expression

EXP

Ascorbic Acid results in decreased expression of SOX11 mRNA

NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:49,736,304...49,738,691

G

SRY-box transcription factor 13

multiple interactions

ISO

[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of SOX13 mRNA

NCBI chr13:47,383,145...47,427,572
Ensembl chr13:47,383,145...47,435,663

G

SRY-box transcription factor 2

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of SOX2 mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA

PMID:21166886 PMID:28189605 PMID:34480604

NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350

G

SRY-box transcription factor 9

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX9 mRNA; [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]; resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]]

PMID:26424790 PMID:26526931

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

Sp1 transcription factor

decreases expression

ISO

Ascorbic Acid results in decreased expression of SP1 protein

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

Sp3 transcription factor

decreases expression

ISO

Ascorbic Acid results in decreased expression of SP3 protein

NCBI chr 3:78,219,421...78,272,318
Ensembl chr 3:78,219,426...78,264,517

G

Sp4 transcription factor

decreases expression

ISO

Ascorbic Acid results in decreased expression of SP4 protein

NCBI chr 6:145,330,416...145,395,750
Ensembl chr 6:145,330,416...145,395,146

G

Sp7 transcription factor

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of SP7 mRNA; Ascorbic Acid results in increased expression of SP7 protein
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; carbobenzoxy-leucyl-leucyl-norvalinal inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Deferoxamine inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA]; EGLN1 mRNA affects the reaction [Ascorbic Acid results in increased expression of SP7 protein]; ethyl protocatechuate inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA]; ethyl protocatechuate inhibits the reaction [Ascorbic Acid results in increased expression of SP7 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; SMAD4 protein promotes the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]

PMID:21467157 PMID:25062436 PMID:25932594 PMID:26492236 PMID:32324263 More...

NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559

G

secreted protein acidic and cysteine rich

multiple interactions

ISO

[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPARC protein

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268

G

SPARC like 1

increases expression

ISO

Ascorbic Acid results in increased expression of SPARCL1 mRNA

NCBI chr14:5,937,484...5,968,532
Ensembl chr14:5,914,535...5,969,120

G

secreted phosphoprotein 1

multiple interactions

ISO

[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein; [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA]

PMID:17692823 PMID:26492236 PMID:36682590

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

splA/ryanodine receptor domain and SOCS box containing 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of SPSB1 mRNA]

NCBI chr 5:165,641,255...165,701,482
Ensembl chr 5:165,642,851...165,654,225

G

serine palmitoyltransferase, small subunit B

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA

NCBI chr 2:156,432,509...156,461,936
Ensembl chr 2:156,432,512...156,460,909

G

sequestosome 1

multiple interactions

ISO
EXP

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 mRNA]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein]

PMID:30320191 PMID:32525552 PMID:34480604

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions

ISO

SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462

G

sterol regulatory element binding transcription factor 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

sterol regulatory element binding transcription factor 2

multiple interactions
decreases metabolic processing
increases expression

ISO

SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR mRNA]; SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR protein]
Ascorbic Acid results in decreased metabolism of SREBF2 protein
Ascorbic Acid results in increased expression of SREBF2 mRNA

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943

G

sulfiredoxin 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

somatostatin

increases expression

EXP

Ascorbic Acid results in increased expression of SST mRNA

NCBI chr11:90,461,546...90,462,823
Ensembl chr11:90,461,546...90,462,823

G

steroidogenic acute regulatory protein

multiple interactions

EXP

[Selenium co-treated with retinol acetate co-treated with Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased expression of STAR mRNA]; Ascorbic Acid inhibits the reaction [Cadmium results in decreased expression of STAR mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of STAR mRNA]

PMID:15055539 PMID:18602937 PMID:33372294

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

signal transducer and activator of transcription 1

multiple interactions
decreases expression

ISO

Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]
Ascorbic Acid results in decreased expression of STAT1 mRNA

PMID:16896058 PMID:30597948

NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346

G

signal transducer and activator of transcription 3

multiple interactions
affects expression

ISO

Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]
Ascorbic Acid affects the expression of STAT3 mRNA

PMID:16896058 PMID:30597948

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

signal transducer and activator of transcription 6

affects expression

ISO

Ascorbic Acid affects the expression of STAT6 mRNA

NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795

G

serine/threonine kinase 17b

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of STK17B mRNA

NCBI chr 9:62,801,912...62,832,511
Ensembl chr 9:62,803,005...62,832,511

G

stathmin 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA

NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335

G

succinate-CoA ligase GDP-forming subunit beta

affects expression

ISO

Ascorbic Acid affects the expression of SUCLG2 protein

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296

G

sulfotransferase family 1A member 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of SULT1A1 mRNA

NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131

G

sulfotransferase family 1C member 3

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of SULT1C1 mRNA

NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295

G

sulfotransferase family 2A member 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of SULT2A1 mRNA

NCBI chr 1:84,582,011...84,639,001

G

sulfatase modifying factor 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of SUMF1 mRNA]

NCBI chr 4:142,634,766...142,716,726
Ensembl chr 4:142,634,767...142,716,712

G

SUV39H1 histone lysine methyltransferase

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H1 mRNA

NCBI chr X:17,093,059...17,105,942
Ensembl chr X:17,092,986...17,105,942

G

SUV39H1 histone lysine methyltransferase, pseudogene 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H1 mRNA

NCBI chr X:146,828,818...146,831,485

G

SUV39H2 histone lysine methyltransferase

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H2 mRNA

NCBI chr17:79,665,467...79,684,492
Ensembl chr17:79,665,376...79,684,492

G

synapsin I

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Corticosterone results in decreased expression of SYN1 protein]

NCBI chr X:3,725,745...3,780,940
Ensembl chr X:3,725,714...3,780,938

G

synaptotagmin 7

increases expression

ISO

Ascorbic Acid results in increased expression of SYT7 mRNA

NCBI chr 1:216,456,148...216,518,718
Ensembl chr 1:216,456,259...216,518,718

G

tafazzin, phospholipid-lysophospholipid transacylase

multiple interactions

ISO

[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of TAFAZZIN mRNA

NCBI chr X:157,216,826...157,230,524
Ensembl chr X:157,216,554...157,225,287

G

transgelin

multiple interactions
increases expression

ISO

[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of TAGLN mRNA
Ascorbic Acid results in increased expression of TAGLN mRNA

NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563

G

threonyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of TARS1 mRNA

NCBI chr 2:62,095,978...62,114,802
Ensembl chr 2:62,087,763...62,114,802

G

TBC1 domain family, member 4

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TBC1D4 protein]

NCBI chr15:84,670,756...84,848,876
Ensembl chr15:84,670,756...84,848,693

G

T-box transcription factor 2

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA

NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275

G

transcription factor 19

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of TCF19 mRNA

NCBI chr20:3,223,464...3,227,569
Ensembl chr20:3,223,324...3,230,060

G

transcription factor 20

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TCF20 mRNA

NCBI chr 7:115,833,523...116,009,790
Ensembl chr 7:115,834,416...115,931,915

G

transcobalamin 2

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of TCN2 mRNA]

NCBI chr14:83,036,935...83,052,187
Ensembl chr14:83,036,935...83,051,552

G

thymine-DNA glycosylase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TDG protein]

NCBI chr 7:22,965,388...22,990,311
Ensembl chr 7:22,965,388...22,985,100

G

TEN1 subunit of CST complex

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of TEN1 mRNA]

NCBI chr10:101,930,212...101,951,932
Ensembl chr10:101,930,222...101,953,979

G

telomerase reverse transcriptase

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA

NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111

G

tet methylcytosine dioxygenase 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TET1 protein]

NCBI chr20:25,766,806...25,839,598
Ensembl chr20:25,760,057...25,832,730

G

tet methylcytosine dioxygenase 2

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TET2 protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased stability of TET2 protein]

PMID:33388378 PMID:38185084

NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:224,662,654...224,746,186

G

transferrin

multiple interactions
increases expression

ISO
EXP

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of TF mRNA
Ascorbic Acid results in increased expression of TF mRNA

PMID:15372504 PMID:17639512 PMID:34480604

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transcription factor AP-2 alpha

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA

NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219

G

trefoil factor 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of TFF2 mRNA

NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,217,121...9,220,979

G

transferrin receptor

multiple interactions

ISO

[Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta 1

multiple interactions
increases expression

EXP
ISO

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TGFB1 mRNA; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in increased expression of TGFB1 mRNA]; Ascorbic Acid inhibits the reaction [Dibutyl Phthalate results in increased expression of TGFB1 protein]
Ascorbic Acid results in increased expression of TGFB1 mRNA
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 protein; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of TAGLN mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of TGFB1 mRNA

PMID:14566779 PMID:17639512 PMID:18544905 PMID:18607632 PMID:28415704

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor, beta 2

increases expression

ISO

Ascorbic Acid results in increased expression of TGFB2 mRNA

NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856

G

transforming growth factor, beta 3

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein; [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA; [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA; [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA; [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]; IL1B protein results in decreased susceptibility to [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]]

PMID:26526931 PMID:33713149

NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946

G

tyrosine hydroxylase

increases expression
decreases expression
multiple interactions

EXP
ISO

Ascorbic Acid results in increased expression of TH mRNA; Ascorbic Acid results in increased expression of TH protein
Ascorbic Acid results in decreased expression of TH protein
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of TH protein

PMID:15372504 PMID:18772553 PMID:22285708 PMID:25891525

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227

G

THUMP domain containing 1

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of THUMPD1 mRNA]

NCBI chr 1:183,510,242...183,516,282
Ensembl chr 1:183,431,657...183,516,282

G

TIMP metallopeptidase inhibitor 1

increases expression
multiple interactions

ISO
EXP

Ascorbic Acid results in increased expression of TIMP1 protein
[Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA; [juglone co-treated with Ascorbic Acid] affects the expression of TIMP1 mRNA
Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein]
Ascorbic Acid results in increased expression of TIMP1 mRNA

PMID:12510807 PMID:15372504 PMID:20881940 PMID:27381660 PMID:29992683

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

tight junction protein 1

multiple interactions

EXP

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of TJP1 protein]

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

toll-like receptor 2

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194

G

toll-like receptor 4

multiple interactions

ISO

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007

G

transmembrane 4 L six family member 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of TM4SF1 mRNA

NCBI chr 2:143,606,980...143,616,176
Ensembl chr 2:143,603,271...143,616,176

G

transmembrane 4 L six family member 4

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA

NCBI chr 2:143,720,220...143,771,283
Ensembl chr 2:143,720,267...143,771,227

G

transmembrane protein 176B

increases expression

EXP

Ascorbic Acid results in increased expression of TMEM176B mRNA

NCBI chr 4:79,097,808...79,105,263
Ensembl chr 4:79,097,808...79,105,263

G

transmembrane protein 245

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of TMEM245 mRNA]

NCBI chr 5:76,366,157...76,443,108
Ensembl chr 5:76,366,157...76,442,888

G

transmembrane serine protease 6

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of TMPRSS6 mRNA

NCBI chr 7:111,871,504...111,902,127
Ensembl chr 7:111,871,031...111,902,116

G

tumor necrosis factor

multiple interactions

ISO
EXP

[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ascorbic Acid promotes the reaction [Quartz results in increased expression of TNF mRNA]; Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of TNF protein]; Ascorbic Acid deficiency promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; Ascorbic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [Sodium Fluoride results in increased expression of TNF protein]
[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; [Ascorbic Acid co-treated with neohesperidin co-treated with pycnogenols co-treated with Tocopherols co-treated with Hyaluronic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Vehicle Emissions] which results in increased expression of TNF mRNA]; Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Ascorbic Acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; Ascorbic Acid promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]

PMID:12723939 PMID:15158148 PMID:19298665 PMID:19429265 PMID:22728154 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 11B

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of TNFRSF11B mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA]

PMID:17664058 PMID:26424790

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF superfamily member 10

multiple interactions
decreases response to substance

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of TNFSF10 mRNA; Ascorbic Acid inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased chemical synthesis of Reactive Oxygen Species]
Ascorbic Acid results in decreased susceptibility to TNFSF10 protein

PMID:17639512 PMID:23711929

NCBI chr 2:112,136,550...112,155,903

G

TNF superfamily member 11

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of and results in increased secretion of TNFSF11 protein

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

translocase of outer mitochondrial membrane 7

decreases expression
multiple interactions

ISO

Ascorbic Acid results in decreased expression of TOMM7 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of TOMM7 mRNA

NCBI chr 4:12,197,503...12,204,344
Ensembl chr 4:12,197,491...12,204,343

G

tumor protein p53

multiple interactions

ISO
EXP

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of TRP53 mRNA; Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of TRP53 mRNA]
Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of and results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of TP53 mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased localization of TP53 protein modified form]
[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; [juglone co-treated with Ascorbic Acid] results in increased phosphorylation of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 protein]; Ascorbic Acid promotes the reaction [Cisplatin results in increased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]

PMID:17917374 PMID:20067818 PMID:20530418 PMID:21262251 PMID:21429301 More...

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein, translationally-controlled 1

increases expression

ISO

Ascorbic Acid results in increased expression of TPT1 mRNA

NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554

G

thyrotropin releasing hormone

decreases expression

ISO

Ascorbic Acid results in decreased expression of TRH mRNA

NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762

G

tribbles pseudokinase 3

multiple interactions
decreases expression

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of TRIB3 mRNA
Ascorbic Acid results in decreased expression of TRIB3 mRNA

PMID:17639512 PMID:19197388

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802

G

tripartite motif-containing 28

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TRIM28 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TRIM28 protein modified form]

PMID:25977998 PMID:28285367

NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572

G

thyroid hormone receptor interactor 10

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of TRIP10 mRNA

NCBI chr 9:2,219,695...2,234,771
Ensembl chr 9:2,220,658...2,235,027

G

transient receptor potential cation channel, subfamily C, member 5

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Resveratrol promotes the reaction [Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]

NCBI chr X:112,742,828...113,027,638
Ensembl chr X:112,742,828...113,027,638

G

transient receptor potential cation channel, subfamily V, member 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TRPV1 protein]

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021

G

thyroid stimulating hormone subunit beta

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of TSHB protein]

NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984

G

translocator protein

increases expression

EXP

Ascorbic Acid results in increased expression of TSPO mRNA

NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460

G

tetratricopeptide repeat domain 32

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of TTC32 mRNA]

NCBI chr 6:37,553,628...37,560,227
Ensembl chr 6:37,553,628...37,561,821

G

transthyretin

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA

NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969

G

tubulin, beta 3 class III

multiple interactions

ISO

[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein

NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740

G

thioredoxin 1

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of TXN1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of TXN1 mRNA]

PMID:21344382 PMID:23470461

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307

G

thioredoxin 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of TXN2 mRNA]

NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:111,386,805...111,390,022

G

thioredoxin interacting protein

increases expression

EXP

Ascorbic Acid results in increased expression of TXNIP mRNA

NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731

G

thioredoxin reductase 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

thioredoxin reductase 2

multiple interactions

EXP

Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of TXNRD2 mRNA]

NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475

G

tyrosine kinase 2

decreases expression

ISO

Ascorbic Acid results in decreased expression of TYK2 mRNA

NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278

G

tyrosinase

multiple interactions
increases oxidation

ISO

ethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]

NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857

G

ubiquitin-conjugating enzyme E2A

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of UBE2A mRNA

NCBI chr X:120,979,993...120,990,773
Ensembl chr X:120,978,790...120,990,750

G

UDP glucuronosyltransferase 1 family, polypeptide A2

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UGT1A2 mRNA

NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 1 member A6a

multiple interactions

EXP

UGT1A6 protein affects the reaction [Methylcholanthrene results in increased abundance of Ascorbic Acid]

NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 1 member A9

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in increased expression of UGT1A9 mRNA

NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 2 member A3

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA

NCBI chr14:20,851,970...20,869,974
Ensembl chr14:20,851,969...20,869,973

G

UDP glucuronosyltransferase 2 family, polypeptide B1

multiple interactions

EXP

UGT2B17 protein affects the reaction [Phenobarbital results in increased abundance of Ascorbic Acid]

NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331

G

ubiquitin-like with PHD and ring finger domains 1

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of UHRF1 mRNA

NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792

G

ubiquitin like with PHD and ring finger domains 2

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of UHRF2 mRNA

NCBI chr 1:237,224,050...237,291,406
Ensembl chr 1:237,228,456...237,292,353

G

uracil-DNA glycosylase

multiple interactions

ISO

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UNG mRNA

NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257

G

uroporphyrinogen decarboxylase

increases expression

EXP

Ascorbic Acid results in increased expression of UROD mRNA

NCBI chr 5:135,701,294...135,705,380
Ensembl chr 5:135,701,296...135,705,380

G

vascular cell adhesion molecule 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of VCAM1 mRNA; Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of VCAM1 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 protein]

PMID:16443354 PMID:25305479 PMID:34480604 PMID:35349355

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801

G

voltage-dependent anion channel 1

multiple interactions

ISO

VDAC1 protein results in increased susceptibility to [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram]

NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541

G

vascular endothelial growth factor A

multiple interactions

ISO

[Ascorbic Acid co-treated with Quartz] results in increased expression of VEGFA mRNA; [juglone co-treated with Ascorbic Acid] results in decreased expression of VEGFA mRNA

PMID:27381660 PMID:29992683

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

VGF nerve growth factor inducible

multiple interactions

EXP

[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased expression of VGF mRNA]; [Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in increased expression of VGF mRNA]

PMID:37704839 PMID:39325335

NCBI chr12:25,274,004...25,281,803
Ensembl chr12:25,273,333...25,282,703

G

vestigial-like family member 1

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA

NCBI chr X:140,016,938...140,036,348

G

von Hippel-Lindau tumor suppressor

multiple interactions

ISO

[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]

NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:148,328,079...148,334,991

G

vimentin

increases expression

ISO

Ascorbic Acid results in increased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

G

vasoactive intestinal peptide

affects expression

EXP

Ascorbic Acid affects the expression of VIP protein

NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:44,470,462...44,478,558

G

vanin 3

affects expression
increases expression

ISO

Ascorbic Acid affects the expression of VNN3P mRNA
Ascorbic Acid deficiency results in increased expression of VNN3P mRNA

NCBI chr 1:23,390,596...23,402,858
Ensembl chr 1:23,390,596...23,402,858

G

VPS41 subunit of HOPS complex

decreases expression

ISO

Ascorbic Acid results in decreased expression of VPS41 mRNA

NCBI chr17:50,758,732...50,923,129
Ensembl chr17:50,758,734...50,923,133

G

VRK serine/threonine kinase 1

multiple interactions

ISO

[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of VRK1 mRNA

NCBI chr 6:130,679,400...130,746,089
Ensembl chr 6:130,679,515...130,746,752

G

VRK serine/threonine kinase 3

multiple interactions

EXP

[Ascorbic Acid co-treated with alpha-Tocopherol] inhibits the reaction [sodium arsenite results in decreased expression of VRK3 mRNA]

NCBI chr 1:104,379,903...104,407,278
Ensembl chr 1:104,379,628...104,407,274

G

vitronectin

increases expression
multiple interactions

ISO

Ascorbic Acid results in increased expression of VTN mRNA
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA

PMID:15305145 PMID:34480604

NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860

G

tryptophanyl-tRNA synthetase 1

decreases expression

ISO

Ascorbic Acid results in decreased expression of WARS1 mRNA

NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645

G

tryptophanyl tRNA synthetase 2 (mitochondrial)

decreases expression

ISO

Ascorbic Acid results in decreased expression of WARS2 mRNA

NCBI chr 2:189,150,322...189,233,606
Ensembl chr 2:189,145,371...189,232,970

G

Wnt family member 1

multiple interactions

ISO

[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein]

NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:131,817,558...131,821,605

G

Wnt family member 11

multiple interactions

ISO

[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of WNT11 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of WNT11 mRNA]

NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660

G

Wnt family member 3A

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919

G

WW domain containing transcription regulator 1

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of WWTR1 mRNA

NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950

G

xanthine dehydrogenase

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased activity of XDH protein]

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350

G

X-prolyl aminopeptidase 2

multiple interactions

ISO

[Quercetin co-treated with Ascorbic Acid] results in decreased expression of XPNPEP2 mRNA

NCBI chr X:132,165,696...132,194,937
Ensembl chr X:132,165,701...132,195,126

G

X-ray repair cross complementing 1

multiple interactions

ISO

Ascorbic Acid inhibits the reaction [Fenretinide results in decreased expression of XRCC1 protein]; Ascorbic Acid inhibits the reaction [Reactive Oxygen Species results in decreased expression of XRCC1 protein]; Ascorbic Acid inhibits the reaction [XRCC1 mutant form results in increased susceptibility to chromium hexavalent ion]

PMID:16124896 PMID:22241526

NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

affects expression

ISO

Ascorbic Acid affects the expression of YWHAE protein

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:61,106,716...61,114,291

G

zinc finger DHHC-type palmitoyltransferase 2

increases expression

EXP

Ascorbic Acid results in increased expression of ZDHHC2 mRNA

NCBI chr16:58,511,931...58,581,530
Ensembl chr16:58,511,934...58,581,516

G

zinc finger AN1-type containing 2A

multiple interactions

ISO

[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA

NCBI chr12:20,275,435...20,286,513
Ensembl chr12:20,275,450...20,286,513

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20874
role	20844
chemical role	20219
donor	17885
Bronsted acid	17870
oxoacid	17853
carbon oxoacid	17678
carboxylic acid	17675
carbohydrate acid	868
ketoaldonic acid	814
(7R)-6-deoxy-D-manno-oct-7-ulosuronic acid	0
(R)-2,4-dihydroxy-3-oxobutanoic acid	0
(R)-3,4-dihydroxy-2-oxobutanoic acid	0
(S)-2,4-dihydroxy-3-oxobutanoic acid	0
(S)-3,4-dihydroxy-2-oxobutanoic acid	0
2,4-didehydro-3-deoxy-L-rhamnonic acid	0
2-dehydro-3-deoxy-D-arabinonic acid	0
2-dehydro-3-deoxy-D-fuconic acid	0
2-dehydro-3-deoxy-D-galactonic acid	0
2-dehydro-3-deoxy-D-gluconic acid	0
2-dehydro-3-deoxy-L-arabinonic acid	0
2-dehydro-3-deoxy-L-fuconic acid	0
2-dehydro-3-deoxy-L-rhamnonic acid	0
2-dehydro-L-idonic acid	0
2-deoxy-D-gluc-5-ulosonic acid	0
2-keto-3-deoxy-L-galactonic acid	0
3,7-dideoxy-D-threo-hepto-2,6-diuolosonic acid	0
3-dehydro-2-deoxy-D-gluconic acid	0
3-dehydro-L-gulonic acid	0
3-deoxy-D-manno-octulosonic acid +	0
3-deoxy-L-threo-hex-2-ulopyranosonic acid	0
5-dehydro-D-gluconic acid	0
7-epi-Kdo	0
ascorbic acid +	813
deaminoneuraminic acid +	0
Path 2
Term	Annotations
CHEBI ontology	20874
subatomic particle	20883
composite particle	20883
hadron	20872
baryon	20883
nucleon	20872
atomic nucleus	20883
atom	20872
main group element atom	20796
p-block element atom	20796
carbon group element atom	20712
carbon atom	20706
organic molecular entity	20706
heteroorganic entity	20201
organochalcogen compound	19822
organooxygen compound	19713
carbohydrates and carbohydrate derivatives	15263
carbohydrate	6585
carbohydrate acid	868
ketoaldonic acid	814
(7R)-6-deoxy-D-manno-oct-7-ulosuronic acid	0
(R)-2,4-dihydroxy-3-oxobutanoic acid	0
(R)-3,4-dihydroxy-2-oxobutanoic acid	0
(S)-2,4-dihydroxy-3-oxobutanoic acid	0
(S)-3,4-dihydroxy-2-oxobutanoic acid	0
2,4-didehydro-3-deoxy-L-rhamnonic acid	0
2-dehydro-3-deoxy-D-arabinonic acid	0
2-dehydro-3-deoxy-D-fuconic acid	0
2-dehydro-3-deoxy-D-galactonic acid	0
2-dehydro-3-deoxy-D-gluconic acid	0
2-dehydro-3-deoxy-L-arabinonic acid	0
2-dehydro-3-deoxy-L-fuconic acid	0
2-dehydro-3-deoxy-L-rhamnonic acid	0
2-dehydro-L-idonic acid	0
2-deoxy-D-gluc-5-ulosonic acid	0
2-keto-3-deoxy-L-galactonic acid	0
3,7-dideoxy-D-threo-hepto-2,6-diuolosonic acid	0
3-dehydro-2-deoxy-D-gluconic acid	0
3-dehydro-L-gulonic acid	0
3-deoxy-D-manno-octulosonic acid +	0
3-deoxy-L-threo-hex-2-ulopyranosonic acid	0
5-dehydro-D-gluconic acid	0
7-epi-Kdo	0
ascorbic acid +	813
deaminoneuraminic acid +	0

paths to the root