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1,2-diacyl-sn-glycero-3-phosphocholine(1+) - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-diacyl-sn-glycero-3-phosphocholine(1+)
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Accession:CHEBI:16110 term browser browse the term
Definition:A phosphatidylcholine that is a glycerol phosphatide (phosphoglyceride, glycerophospholipid) in which the hydroxy group of choline is esterified with the phosphate group of phosphatidic acid.
Synonyms:related_synonym: (3-sn-phosphatidyl)choline;   1,2-Diacyl-sn-glycero-3-phosphocholine;   1,2-diacyl-sn-glycero-3-phosphocholines;   Choline phosphatide;   Formula=C10H19NO8PR2;   L-alpha-phosphatidylcholine;   Lecithin;   PC;   Phosphatidyl-N-trimethylethanolamine;   Phosphatidylcholine;   SMILES=C[N+](C)(C)CCOP(O)(=O)OC[C@@H](COC([*])=O)OC([*])=O;   lecithins
 alt_id: CHEBI:11148;   CHEBI:11753;   CHEBI:1681;   CHEBI:18878;   CHEBI:20200;   CHEBI:23660;   CHEBI:26029;   CHEBI:44694;   CHEBI:8128
 xref: CAS:8002-43-5;   KEGG:C00157;   PDBeChem:PC1;   PMID:16341241;   PMID:3196084;   PMID:7192727
 cyclic_relationship: is_conjugate_acid_of CHEBI:57643

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1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO		 [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein
[1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein		 CTD PMID:1627548 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO 1,2-dilauroylphosphatidylcholine results in increased expression of NR5A2 CTD PMID:24459144 NCBI chr13:50,865,253...50,985,107
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pon1 paraoxonase 1 increases activity ISO 1,2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      application 19697
        pharmaceutical 19534
          drug 19534
            1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
              1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-dicaproyl-sn-glycero-3-phosphocholine 0
              1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
              1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
              1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
              1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
              1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
              1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
              1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
              1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
              1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
              1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
              1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
              2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
              \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            inorganic hydride 18162
                              pnictogen hydride 18152
                                nitrogen hydride 18059
                                  ammonium 8311
                                    ammonium ion derivative 8306
                                      quaternary ammonium ion 5296
                                        phosphatidylcholine(1+) 5
                                          1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
                                            1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-dicaproyl-sn-glycero-3-phosphocholine 0
                                            1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
                                            1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
                                            1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
                                            1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
                                            1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
                                            1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
                                            \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
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