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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phosphatidylcholine(1+)
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Accession:CHEBI:49183 term browser browse the term
Definition:A glycerophosphocholine compound having O-acyl substituents at both the 1- and 2-positions of the glycerol. It is a major constituent of cell membranes.
Synonyms:related_synonym: 1,2-Diacyl-sn-glycero-3-phosphocholine;   3-sn-Phosphatidylcholine;   Choline phosphatide;   Formula=C10H19NO8PR2;   Lecithin;   Lecithol;   PC;   Phosphatidyl-N-trimethylethanolamine;   Phospholutein;   SMILES=C[N+](C)(C)CCOP(O)(=O)OCC(COC([*])=O)OC([*])=O;   phosphatidylcholines
 alt_id: CHEBI:14802;   CHEBI:36705
 xref: CAS:8002-43-5;   KEGG:C00157;   PMID:11306571;   PMID:11394647;   PMID:11829744;   PMID:14756787;   PMID:14761824;   PMID:15008874;   PMID:15223015;   PMID:16484204;   PMID:16829536;   PMID:16882035;   PMID:18614529;   PMID:19843309;   PMID:22809594;   PMID:22922101;   PMID:23207112;   PMID:23452035;   PMID:23519169;   PMID:23543734;   PMID:3196084;   Wikipedia:Phosphatidylcholine
 cyclic_relationship: is_conjugate_acid_of CHEBI:64482


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1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein CTD PMID:1627548 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein CTD PMID:1627548 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO 1,2-dilauroylphosphatidylcholine results in increased expression of NR5A2 CTD PMID:24459144 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Pon1 paraoxonase 1 increases activity ISO 1,2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
dioleoyl phosphatidylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein CTD PMID:1627548 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein CTD PMID:1627548 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects binding ISO LCAT protein binds to 1,2-oleoylphosphatidylcholine CTD PMID:16780378 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO 1,2-oleoylphosphatidylcholine inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein] CTD PMID:12871208 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19771
        ion 15935
          organic ion 8447
            organic cation 7303
              quaternary ammonium ion 5090
                phosphatidylcholine(1+) 5
                  1,2-diacyl-sn-glycero-3-phosphocholine(1+) + 4
                  10-(perfluorobutyl)decyl phosphatidylcholine 0
                  2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
                  dioleoyl phosphatidylcholine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            inorganic hydride 17457
                              pnictogen hydride 17432
                                nitrogen hydride 17277
                                  ammonium 8210
                                    ammonium ion derivative 8206
                                      quaternary ammonium ion 5090
                                        phosphatidylcholine(1+) 5
                                          1,2-diacyl-sn-glycero-3-phosphocholine(1+) + 4
                                          10-(perfluorobutyl)decyl phosphatidylcholine 0
                                          2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
                                          dioleoyl phosphatidylcholine 4
paths to the root