CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2',4,4',6'-tetrahydroxychalcone
Accession: CHEBI:15413
browse the term
Definition: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively.
Synonyms: exact_synonym: (2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
related_synonym: Chalconaringenin; Formula=C15H12O5; InChI=1S/C15H12O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-8,16-17,19-20H/b6-3+; InChIKey=YQHMWTPYORBCMF-ZZXKWVIFSA-N; Isosalipurpol; Naringenin chalcone; SMILES=Oc1ccc(cc1)\\C=C\\C(=O)c1c(O)cc(O)cc1O
alt_id: CHEBI:10785; CHEBI:14641; CHEBI:19219; CHEBI:6055
xref: CAS:73692-50-9; KEGG:C06561; KNApSAcK:C00007233; LIPID_MAPS_instance:LMPK12120264
xref_mesh: MESH:C027329
xref: PMID:15322354; PMID:17915259; PMID:20035147; PMID:20363289; PMID:20815398; Reaxys:2335724
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases glucuronidation
ISO
UGT1A1 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases glucuronidation
ISO
UGT1A9 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19841
role
19817
application
19661
anti-inflammatory agent
16598
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0
Path 2
CHEBI ontology
19841
subatomic particle
19839
composite particle
19839
hadron
19839
baryon
19839
nucleon
19839
atomic nucleus
19839
atom
19839
main group element atom
19789
p-block element atom
19789
carbon group element atom
19737
carbon atom
19733
organic molecular entity
19733
heteroorganic entity
19492
organochalcogen compound
19255
organooxygen compound
19172
carbonyl compound
18898
ketone
17187
alpha,beta-unsaturated ketone
9969
enone
9969
chalcones
934
chalcone
114
trans-chalcone
114
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0