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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chalcones
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Accession:CHEBI:23086 term browser browse the term
Definition:A ketone that is 1,3-diphenylpropenone (benzylideneacetophenone), ArCH=CH(=O)Ar, and its derivatives formed by substitution.
Synonyms:related_synonym: chalconoid;   chalconoids
 xref: KEGG:C15589
 xref_mesh: MESH:D047188


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chalcones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased expression of BAX protein]
Chalcones analog results in increased expression of BAX mRNA; Chalcones analog results in increased expression of BAX protein
CTD PMID:30576621 PMID:32856275 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO Chalcones analog results in decreased expression of BCL2 mRNA; Chalcones analog results in decreased expression of BCL2 protein; Chalcones results in decreased expression of BCL2 protein
BCL2 protein inhibits the reaction [Chalcones analog results in decreased expression of BID protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP4 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP6 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP7 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of PARP1 protein]; BCL2 protein inhibits the reaction [Chalcones analog results in increased expression of BAX protein]
CTD PMID:23562496 PMID:30576621 PMID:32856275 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression
ISO BCL2 protein inhibits the reaction [Chalcones analog results in decreased expression of BID protein] CTD PMID:30576621 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects binding ISO Chalcones analog binds to BIRC2 protein CTD PMID:32856275 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP3 protein]; Chalcones analog results in increased cleavage of and results in increased activity of CASP3 protein
Chalcones analog results in increased expression of CASP3 mRNA
CTD PMID:30576621 PMID:32856275 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases cleavage
multiple interactions
ISO Chalcones analog results in increased cleavage of CASP4 protein
BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP4 protein]
CTD PMID:30576621 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 multiple interactions
increases cleavage
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP6 protein] CTD PMID:30576621 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
ISO Chalcones analog results in increased cleavage of CASP7 protein
BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of CASP7 protein]
CTD PMID:30576621 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP8 protein]; Chalcones analog results in increased cleavage of and results in increased activity of CASP8 protein
Chalcones analog results in increased expression of CASP8 mRNA
CTD PMID:30576621 PMID:32856275 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP9 protein]; Chalcones analog results in increased cleavage of and results in increased activity of CASP9 protein
Chalcones analog results in increased expression of CASP9 mRNA
CTD PMID:30576621 PMID:32856275 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity EXP Chalcones analog results in increased activity of CAT protein CTD PMID:23963778 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Chalcones analog results in decreased expression of CDK4 mRNA CTD PMID:32856275 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP Chalcones analog results in increased activity of GSR protein CTD PMID:23963778 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein] CTD PMID:22410118 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Chalcones analog results in decreased expression of KEAP1 protein CTD PMID:23963778 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO Chalcones analog results in decreased expression of MMP1 mRNA CTD PMID:32856275 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO Chalcones results in decreased expression of MMP9 mRNA
Chalcones results in decreased expression of and results in decreased activity of MMP9 protein
CTD PMID:23562496 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22410118 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Chalcones analog results in decreased expression of COX1 protein CTD PMID:32856275 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression EXP Chalcones analog results in increased expression of NFE2L2 protein CTD PMID:23963778 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Chalcones analog results in increased expression of NQO1 protein CTD PMID:23963778 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of PARP1 protein] CTD PMID:30576621 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein] CTD PMID:22410118 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein] CTD PMID:22410118 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Chalcones inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
CTD PMID:18720166 PMID:22410118 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Chalcones analog results in increased expression of TP53 mRNA CTD PMID:32856275 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Chalcones analog results in increased expression of UGT1A1 protein CTD PMID:23963778 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Chalcones analog results in decreased expression of VEGFA protein CTD PMID:32856275 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]
CTD PMID:31029725 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA; 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein
CTD PMID:31029725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein] CTD PMID:31029725 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA] CTD PMID:31029725 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:31029725 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:31029725 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased phosphorylation of MAPK8 protein
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]
CTD PMID:31029725 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein]
CTD PMID:31029725 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of and affects the stability of NFKBIA protein] CTD PMID:31029725 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]
CTD PMID:31029725 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]
CTD PMID:31029725 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA] CTD PMID:31029725 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
2',4,4',6'-tetrahydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of naringenin chalcone CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of naringenin chalcone CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
2',5'-Dihydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 increases response to substance
multiple interactions
ISO ABCG2 protein results in increased susceptibility to 2',5'-dihydroxychalcone
2',5'-dihydroxychalcone promotes the reaction [ABCG2 protein results in increased export of Glutathione]
CTD PMID:20332504 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 2',5'-dihydroxychalcone CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2',5'-dihydroxychalcone CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
2'-hydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO 2'-hydroxychalcone results in decreased activity of CYP1A1 protein
2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]
CTD PMID:15596260 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
ISO 2'-hydroxychalcone results in decreased activity of CYP1B1 protein
2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:15596260 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 2'-hydroxychalcone results in increased expression of HMOX1 protein CTD PMID:23942037 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
2,4-Dihydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO 2',4'-dihydroxychalcone results in decreased expression of BIRC5 mRNA CTD PMID:20471467 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 increases activity ISO 2',4'-dihydroxychalcone results in increased activity of CASP3 protein CTD PMID:20471467 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 2',4'-dihydroxychalcone CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2',4'-dihydroxychalcone CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
4'-hydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP 4'-hydroxychalcone binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4'-hydroxychalcone binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
4'-Methoxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
ISO [4'-methoxychalcone analog co-treated with TNF protein] results in increased expression of ADIPOQ mRNA
4'-methoxychalcone analog results in increased expression of ADIPOQ mRNA
CTD PMID:28528971 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] CTD PMID:28528971 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of FABP4 mRNA]
4'-methoxychalcone analog results in increased expression of FABP4 mRNA
CTD PMID:28528971 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO 4'-methoxychalcone analog results in increased expression of FASN mRNA
4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of FASN mRNA]
CTD PMID:28528971 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:28528971 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of PPARG mRNA]; 4'-methoxychalcone analog results in increased expression of and results in increased activity of PPARG protein
4'-methoxychalcone analog results in increased expression of PPARG mRNA
CTD PMID:28528971 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:28528971 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO 4'-methoxychalcone analog results in increased expression of SLC2A4 mRNA CTD PMID:28528971 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of FABP4 mRNA]; 4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of FASN mRNA]; 4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of PPARG mRNA]; 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; [4'-methoxychalcone analog co-treated with TNF protein] results in increased expression of ADIPOQ mRNA CTD PMID:28528971 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
4-hydroxychalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP 4-hydroxychalcone binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ar androgen receptor affects binding EXP 4-hydroxychalcone binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
affects chemical synthesis
ISO
EXP
4-hydroxychalcone results in decreased activity of CYP1A1 protein
CYP1A1 protein affects the chemical synthesis of 4-hydroxychalcone
CTD PMID:15596260 PMID:15863696 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects chemical synthesis EXP CYP1A2 protein affects the chemical synthesis of 4-hydroxychalcone CTD PMID:15863696 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO 4-hydroxychalcone results in decreased activity of CYP1B1 protein CTD PMID:15596260 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 affects chemical synthesis EXP CYP2C6V1 protein affects the chemical synthesis of 4-hydroxychalcone CTD PMID:15863696 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4-hydroxychalcone binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
butein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO butein results in decreased phosphorylation of AKT1 protein CTD PMID:20696233 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO butein results in increased expression of BAX protein CTD PMID:11055382 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO butein results in decreased expression of BCL2 protein CTD PMID:11055382 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO butein results in decreased expression of BCL2L1 protein CTD PMID:11055382 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases activity ISO butein results in increased activity of CASP3 protein CTD PMID:24931875 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO butein results in decreased activity of DIO2 protein CTD PMID:17327447 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [butein results in increased expression of HMOX1 protein] inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species]; [butein results in increased expression of HMOX1 protein] which results in decreased susceptibility to Hydrogen Peroxide; [tin protoporphyrin IX results in decreased expression of and results in decreased activity of HMOX1 protein] inhibits the reaction [butein inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species]]; butein results in increased expression of and results in increased activity of HMOX1 protein; pyrazolanthrone inhibits the reaction [butein results in increased expression of HMOX1 protein] CTD PMID:23318726 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butein results in decreased expression of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [butein results in decreased expression of MMP9 protein]; Bortezomib promotes the reaction [butein results in decreased expression of MMP9 protein]; butein inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; prolinedithiocarbamate promotes the reaction [butein results in decreased expression of MMP9 protein]
butein results in decreased expression of MMP9 mRNA; butein results in decreased expression of MMP9 protein
CTD PMID:20696233 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization ISO butein affects the localization of NFE2L2 protein CTD PMID:23318726 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization ISO butein affects the localization of NFKB1 protein CTD PMID:20696233 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO butein results in increased activity of NR1I2 protein CTD PMID:29933105 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO butein results in increased cleavage of PARP1 protein CTD PMID:24931875 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression
decreases response to substance
ISO butein results in decreased expression of PTTG1 protein
PTTG1 protein results in decreased susceptibility to butein
CTD PMID:24931875 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization ISO butein affects the localization of RELA protein CTD PMID:20696233 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sirt1 sirtuin 1 increases activity ISO butein results in increased activity of SIRT1 protein CTD PMID:17327447 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO butein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; butein inhibits the reaction [TNF protein results in increased expression of MMP9 protein] CTD PMID:20696233 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO butein results in decreased expression of VEGFA mRNA CTD PMID:20696233 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
chalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP Chalcone binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ar androgen receptor affects binding EXP Chalcone binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Chalcone results in decreased activity of CA1 protein CTD PMID:30431690 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Chalcone results in decreased activity of CA2 protein CTD PMID:30431690 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO Chalcone results in increased cleavage of CASP3 protein
MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP3 protein]
CTD PMID:20620131 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO Chalcone results in increased cleavage of CASP8 protein
MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP8 protein]
CTD PMID:20620131 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO Chalcone results in increased cleavage of CASP9 protein
MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP9 protein]
CTD PMID:20620131 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydroxylation EXP CYP1A1 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation EXP CYP1A2 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases hydroxylation EXP CYP2C6V1 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases hydroxylation EXP CYP3A23-3A1 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Chalcone analog results in increased expression of GCLM mRNA; Chalcone analog results in increased expression of GCLM protein CTD PMID:31299238 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hat1 histone acetyltransferase 1 decreases activity ISO Chalcone analog results in decreased activity of HAT1 protein CTD PMID:22155221 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:22155221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22155221 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] CTD PMID:22155221 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22155221 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects response to substance
multiple interactions
ISO MYC protein affects the susceptibility to Chalcone
Chalcone promotes the reaction [MYC protein results in increased abundance of Reactive Oxygen Species]; MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP3 protein]; MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP8 protein]; MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP9 protein]; MYC protein affects the susceptibility to [Chalcone results in increased cleavage of PARP1 protein]
CTD PMID:20620131 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO Chalcone analog results in decreased ubiquitination of and results in decreased degradation of and affects the localization of NFE2L2 protein; NFE2L2 promotes the reaction [Chalcone analog results in increased abundance of Glutathione] CTD PMID:31299238 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:22155221 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Chalcone analog inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2] which results in increased abundance of Nitric Oxide]; Chalcone analog inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22155221 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Chalcone analog results in increased expression of NQO1 mRNA; Chalcone analog results in increased expression of NQO1 protein CTD PMID:31299238 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Chalcone results in increased cleavage of PARP1 protein
MYC protein affects the susceptibility to [Chalcone results in increased cleavage of PARP1 protein]
CTD PMID:20620131 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Chalcone analog results in increased expression of PPARG mRNA CTD PMID:28528971 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions EXP [PTGR1 protein co-treated with NADP] affects the reduction of Chalcone CTD PMID:11524419 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Chalcone analog inhibits the reaction [[Lipopolysaccharides results in increased phosphorylation of RELA protein] which results in increased acetylation of RELA protein]; Chalcone analog inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:22155221 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO Chalcone binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:22155221 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Flavokawain A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides affects the localization of [JUN protein binds to FOS protein]] CTD PMID:23727179 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:23727179 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:23727179 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides affects the localization of [JUN protein binds to FOS protein]]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JUN protein] CTD PMID:23727179 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:23727179 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23727179 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:23727179 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:23727179 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; flavokawain A inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:23727179 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
flavokawain B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO flavokawain B results in decreased phosphorylation of AKT1 protein
TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of AKT1 protein]
CTD PMID:30025493 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of ATF4 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of DDIT3 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATF4 protein affects the reaction [flavokawain B results in increased expression of TRIB3 protein] CTD PMID:30025493 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atg5 autophagy related 5 multiple interactions
affects response to substance
ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of CDKN1A protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of GLB1 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MAP1LC3B protein modified form; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MKI67 protein; ATG5 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 affects response to substance
multiple interactions
ISO ATG7 protein affects the susceptibility to flavokawain B
[ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; ATG7 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]
CTD PMID:30025493 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein CTD PMID:30025493 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of CDKN1A protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of CDKN1A protein CTD PMID:30025493 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of DDIT3 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO flavokawain B results in increased phosphorylation of EIF2AK3 protein CTD PMID:30025493 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO flavokawain B results in increased phosphorylation of EIF2S1 protein CTD PMID:30025493 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
increases expression
ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of GLB1 protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of GLB1 protein
flavokawain B results in increased expression of GLB1 protein
CTD PMID:30025493 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO flavokawain B results in increased expression of HSPA5 protein CTD PMID:30025493 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO 3-methyladenine inhibits the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MAP1LC3B protein modified form; [Chloroquine co-treated with flavokawain B] results in increased expression of MAP1LC3B protein modified form; ATF4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG5 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG7 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; DDIT3 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MKI67 protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of MKI67 protein CTD PMID:30025493 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
ISO TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of MTOR protein] CTD PMID:30025493 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [flavokawain B co-treated with 3-methyladenine] results in increased cleavage of PARP1 protein CTD PMID:30025493 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO flavokawain B results in decreased phosphorylation of RPS6KB1 protein
TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein]
CTD PMID:30025493 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO flavokawain B results in increased expression of SQSTM1 protein CTD PMID:30025493 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions
increases expression
ISO ATF4 protein affects the reaction [flavokawain B results in increased expression of TRIB3 protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of AKT1 protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of MTOR protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30025493 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
isobavachalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D decreases activity ISO isobavachalcone results in decreased activity of CES1 protein CTD PMID:26560012 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
EXP isobavachalcone results in decreased activity of CYP2E1 protein
isobavachalcone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
CTD PMID:31870919 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
EXP isobavachalcone inhibits the reaction [[CYP3A4 protein results in increased metabolism of Testosterone] which results in increased chemical synthesis of 6 beta-hydroxytestosterone]
isobavachalcone results in decreased activity of CYP3A4 protein
CTD PMID:31870919 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO isobavachalcone results in increased cleavage of PARP1 protein CTD PMID:30890322 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
isoliquiritigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP isoliquiritigenin binds to AFP protein CTD PMID:23013281 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein] CTD PMID:25110319 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases response to substance
multiple interactions
decreases phosphorylation
ISO AKT1 protein modified form results in decreased susceptibility to isoliquiritigenin
isoliquiritigenin inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Leukotriene B4 inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]
isoliquiritigenin results in decreased phosphorylation of AKT1 protein
CTD PMID:23747687 PMID:25094029 PMID:27117918 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arg1 arginase 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 protein] CTD PMID:25026504 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO isoliquiritigenin results in increased expression of BAX mRNA; isoliquiritigenin results in increased expression of BAX protein CTD PMID:11055382 PMID:27702603 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases phosphorylation ISO isoliquiritigenin results in decreased phosphorylation of BCL2 protein CTD PMID:23747687 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
decreases phosphorylation
ISO isoliquiritigenin results in decreased expression of BCL2L1 protein
isoliquiritigenin results in decreased phosphorylation of BCL2L1 protein
CTD PMID:11055382 PMID:15729620 PMID:23747687 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO isoliquiritigenin results in decreased expression of BIRC2 protein CTD PMID:15729620 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO isoliquiritigenin results in decreased expression of BIRC3 protein CTD PMID:15729620 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; isoliquiritigenin results in increased cleavage of and results in increased activity of CASP3 protein
isoliquiritigenin results in increased activity of CASP3 protein
CTD PMID:15729620 PMID:16158945 PMID:23747687 PMID:25094029 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO isoliquiritigenin results in increased activity of CASP8 protein CTD PMID:16158945 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases cleavage
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; isoliquiritigenin results in increased cleavage of and results in increased activity of CASP9 protein
isoliquiritigenin results in increased activity of CASP9 protein
CTD PMID:16158945 PMID:23747687 PMID:25094029 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:25450236 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cckar cholecystokinin A receptor multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [isoliquiritigenin results in increased expression of CCKAR mRNA] CTD PMID:27702603 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO isoliquiritigenin results in decreased expression of CCND2 mRNA CTD PMID:27702603 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO isoliquiritigenin results in decreased expression of CCNE2 mRNA CTD PMID:27702603 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO isoliquiritigenin results in increased expression of CDKN1A mRNA; isoliquiritigenin results in increased expression of CDKN1A protein CTD PMID:27702603 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO isoliquiritigenin results in decreased expression of CDKN1B mRNA CTD PMID:27702603 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO isoliquiritigenin results in decreased expression of CDKN1C mRNA CTD PMID:27702603 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of CEBPA protein] CTD PMID:27117918 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of CHUK protein] CTD PMID:18295200 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA] CTD PMID:25026504 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO isoliquiritigenin results in decreased expression of CYP17A1 mRNA CTD PMID:27773742 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO isoliquiritigenin results in decreased expression of CYP19A1 mRNA CTD PMID:27773742 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 protein]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:25110319 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
isoliquiritigenin results in decreased activity of CYP1A2 protein
CTD PMID:25110319 PMID:29753067 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]; isoliquiritigenin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
isoliquiritigenin results in increased expression of CYP1B1 mRNA
CTD PMID:25110319 PMID:26134484 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO isoliquiritigenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]; isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25450236 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO isoliquiritigenin results in decreased activity of CYP3A4 protein CTD PMID:29753067 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of FABP4 protein] CTD PMID:27117918 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Gadd45gip1 GADD45G interacting protein 1 increases expression ISO isoliquiritigenin results in increased expression of GADD45GIP1 mRNA CTD PMID:27702603 NCBI chr19:23,320,662...23,323,211
Ensembl chr19:23,320,159...23,323,236
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein] CTD PMID:19834288 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO isoliquiritigenin results in increased expression of HMOX1 protein CTD PMID:23942037 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO isoliquiritigenin results in decreased expression of HSD17B1 mRNA CTD PMID:27773742 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Ifng interferon gamma multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNG protein]; isoliquiritigenin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]
CTD PMID:23942037 PMID:25026504 PMID:26134484 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL10 protein] CTD PMID:25026504 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN protein] CTD PMID:25026504 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6 interleukin 6 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:18295200 PMID:25026504 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insr insulin receptor multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased phosphorylation of INSR protein] CTD PMID:27117918 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO TEMPOL-H inhibits the reaction [isoliquiritigenin results in increased expression of ITGAM protein] CTD PMID:24369695 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:18295200 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:18295200 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO isoliquiritigenin results in decreased expression of MKI67 mRNA; isoliquiritigenin results in decreased expression of MKI67 protein CTD PMID:27702603 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]
isoliquiritigenin results in decreased expression of MMP2 mRNA; isoliquiritigenin results in decreased expression of MMP2 protein
CTD PMID:25094029 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]
isoliquiritigenin results in decreased expression of MMP9 mRNA; isoliquiritigenin results in decreased expression of MMP9 protein
CTD PMID:25094029 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 protein] CTD PMID:25026504 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of NFKB1 protein] CTD PMID:18295200 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
decreases phosphorylation
ISO isoliquiritigenin results in increased expression of NFKBIA protein
isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
isoliquiritigenin results in decreased phosphorylation of NFKBIA protein
CTD PMID:15729620 PMID:18295200 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of NOS2 protein] CTD PMID:18295200 PMID:19834288 PMID:25026504 PMID:26134484 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO isoliquiritigenin results in increased expression of NQO1 protein CTD PMID:26473469 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression
ISO isoliquiritigenin results in increased activity of NR1I2 protein
isoliquiritigenin results in increased expression of NR1I2 mRNA
CTD PMID:29933105 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO isoliquiritigenin results in increased cleavage of PARP1 protein
benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of PARP1 protein]
CTD PMID:23747687 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases phosphorylation ISO isoliquiritigenin results in decreased phosphorylation of PDK1 protein CTD PMID:25094029 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO isoliquiritigenin results in decreased expression of PLA2G5 mRNA CTD PMID:23747687 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of PPARG protein] CTD PMID:27117918 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO isoliquiritigenin results in decreased expression of PTGER4 mRNA; isoliquiritigenin results in decreased expression of PTGER4 protein CTD PMID:25094029 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO isoliquiritigenin results in decreased expression of PTGS1 mRNA CTD PMID:25094029 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO
EXP
isoliquiritigenin results in decreased expression of PTGS2 mRNA
isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]
isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
CTD PMID:18295200 PMID:23747687 PMID:25026504 PMID:25450236 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in decreased activity of and results in increased oxidation of PTPN1 protein] CTD PMID:27117918 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions
decreases activity
ISO isoliquiritigenin affects the localization of RELA protein
isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]
isoliquiritigenin results in decreased activity of RELA protein
CTD PMID:15729620 PMID:18295200 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO isoliquiritigenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
isoliquiritigenin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein] CTD PMID:27117918 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:19834288 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions
decreases activity
EXP [isoliquiritigenin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [isoliquiritigenin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate CTD PMID:32259555 NCBI chr 4:174,877,045...174,950,857
Ensembl chr 4:174,876,593...174,950,873
JBrowse link
G Sod2 superoxide dismutase 2 affects response to substance ISO SOD2 protein affects the susceptibility to isoliquiritigenin CTD PMID:23526725 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO isoliquiritigenin results in increased expression of STAR mRNA CTD PMID:27773742 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein] CTD PMID:25026504 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein] CTD PMID:25026504 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNF protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]
isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
CTD PMID:18295200 PMID:25026504 PMID:25450236 PMID:26134484 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO isoliquiritigenin results in increased expression of TRP53 mRNA CTD PMID:27702603 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
Licochalcone A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO licochalcone A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:26134484 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO licochalcone A results in decreased expression of AKT1 mRNA CTD PMID:30055311 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO licochalcone A results in increased expression of BAD mRNA CTD PMID:30055311 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO licochalcone A results in increased expression of BAK1 mRNA CTD PMID:30055311 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO licochalcone A results in increased expression of BAX mRNA CTD PMID:30055311 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO licochalcone A results in increased expression of BBC3 mRNA CTD PMID:30055311 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO licochalcone A results in increased expression of BCL2 mRNA CTD PMID:30055311 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO licochalcone A results in decreased expression of BIRC5 mRNA CTD PMID:30055311 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
ISO licochalcone A results in increased cleavage of CASP3 protein
SB 203580 inhibits the reaction [licochalcone A results in increased cleavage of CASP3 protein]
licochalcone A results in increased expression of CASP3 mRNA
CTD PMID:30055311 PMID:30983163 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases cleavage
ISO SB 203580 inhibits the reaction [licochalcone A results in increased cleavage of CASP8 protein]
licochalcone A results in increased expression of CASP8 mRNA
CTD PMID:30055311 PMID:30983163 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO licochalcone A results in increased cleavage of CASP9 protein
SB 203580 inhibits the reaction [licochalcone A results in increased cleavage of CASP9 protein]
CTD PMID:30983163 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO licochalcone A results in decreased expression of CCNB1 mRNA CTD PMID:30055311 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO licochalcone A results in increased expression of CCND1 mRNA CTD PMID:30055311 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO licochalcone A results in decreased expression of CDK1 mRNA CTD PMID:30055311 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO licochalcone A results in increased expression of CDKN1A mRNA CTD PMID:30055311 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO licochalcone A results in decreased activity of CYP1A2 protein CTD PMID:26100226 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression
ISO licochalcone A inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]; licochalcone A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
licochalcone A results in decreased expression of CYP1B1 mRNA
CTD PMID:26134484 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO licochalcone A results in decreased activity of CYP2C19 protein CTD PMID:26100226 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO licochalcone A results in decreased activity of CYP2C8 protein CTD PMID:26100226
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects activity ISO licochalcone A affects the activity of CYP2D6 protein CTD PMID:26100226 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects activity ISO licochalcone A affects the activity of CYP2E1 protein CTD PMID:26100226 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO licochalcone A results in decreased activity of CYP3A4 protein CTD PMID:26100226 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases activity ISO licochalcone A results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO licochalcone A results in increased expression of FAS mRNA CTD PMID:30055311 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Ifng interferon gamma multiple interactions ISO licochalcone A inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA] CTD PMID:26134484 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO licochalcone A inhibits the reaction [IL1B protein results in increased abundance of Dinoprost]; licochalcone A inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone] CTD PMID:16354411 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 decreases phosphorylation
multiple interactions
ISO licochalcone A results in decreased phosphorylation of MAP2K4 protein
licochalcone A promotes the reaction [Sorafenib results in decreased phosphorylation of MAP2K4 protein]; Sorafenib promotes the reaction [licochalcone A results in decreased phosphorylation of MAP2K4 protein]
CTD PMID:30187994 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO licochalcone A results in increased phosphorylation of MAPK1 protein CTD PMID:30983163 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO licochalcone A results in increased phosphorylation of MAPK3 protein CTD PMID:30983163 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases expression
decreases phosphorylation
ISO licochalcone A promotes the reaction [Sorafenib results in decreased phosphorylation of MAPK8 protein]; Sorafenib promotes the reaction [licochalcone A results in decreased phosphorylation of MAPK8 protein]
licochalcone A results in increased expression of MAPK8 mRNA
CTD PMID:30055311 PMID:30187994 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases phosphorylation
multiple interactions
ISO licochalcone A results in decreased phosphorylation of MAPK9 protein
licochalcone A promotes the reaction [Sorafenib results in decreased phosphorylation of MAPK9 protein]; Sorafenib promotes the reaction [licochalcone A results in decreased phosphorylation of MAPK9 protein]
CTD PMID:30187994 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO licochalcone A inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:26134484 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO licochalcone A results in increased expression of NQO1 protein CTD PMID:26473469 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO licochalcone A results in increased cleavage of PARP1 protein CTD PMID:30983163 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
decreases expression
ISO licochalcone A promotes the reaction [Sorafenib results in decreased expression of PLAU protein]; Sorafenib promotes the reaction [licochalcone A results in decreased expression of PLAU protein] CTD PMID:30187994 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO licochalcone A results in decreased expression of PRKCE mRNA CTD PMID:30055311 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression ISO licochalcone A results in decreased expression of RPS6KB1 mRNA CTD PMID:30055311 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions
decreases activity
EXP [licochalcone A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [licochalcone A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate CTD PMID:32259555 NCBI chr 4:174,877,045...174,950,857
Ensembl chr 4:174,876,593...174,950,873
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO licochalcone A inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA] CTD PMID:26134484 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO licochalcone A results in increased expression of TNFRSF25 mRNA CTD PMID:30055311 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A1 protein] CTD PMID:26875642 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A3 protein] CTD PMID:26875642 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 multiple interactions ISO licochalcone A inhibits the reaction [Trifluoperazine results in increased activity of UGT1A4 protein] CTD PMID:26875642 NCBI chr 9:88,762,250...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A6 protein] CTD PMID:26875642 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A9 protein]; licochalcone A inhibits the reaction [UGT1A9 protein results in increased glucuronidation of Propofol] CTD PMID:26875642 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT2B17 protein] CTD PMID:26875642 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT2B7 protein] CTD PMID:26875642 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO licochalcone A results in increased expression of WEE1 mRNA CTD PMID:30055311 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
Licochalcone B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO licochalcone B results in decreased expression of ABCA1 mRNA CTD PMID:33647349 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 decreases expression ISO licochalcone B results in decreased expression of ABCA8 mRNA CTD PMID:33647349 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO licochalcone B results in increased expression of ABCB4 mRNA CTD PMID:33647349 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Ache acetylcholinesterase increases expression ISO licochalcone B results in increased expression of ACHE mRNA CTD PMID:33647349 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 increases expression ISO licochalcone B results in increased expression of ACSBG1 mRNA CTD PMID:33647349 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression ISO licochalcone B results in increased expression of ACTA1 mRNA CTD PMID:33647349 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Actn3 actinin alpha 3 increases expression ISO licochalcone B results in increased expression of ACTN3 mRNA CTD PMID:33647349 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression ISO licochalcone B results in decreased expression of ADAMTS5 mRNA CTD PMID:33647349 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Adap1 ArfGAP with dual PH domains 1 increases expression ISO licochalcone B results in increased expression of ADAP1 mRNA CTD PMID:33647349 NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831
JBrowse link
G Adat3 adenosine deaminase, tRNA-specific 3 increases expression ISO licochalcone B results in increased expression of ADAT3 mRNA CTD PMID:33647349 NCBI chr 7:9,109,070...9,113,673
Ensembl chr 7:9,101,187...9,115,340
JBrowse link
G Adgrg3 adhesion G protein-coupled receptor G3 decreases expression ISO licochalcone B results in decreased expression of ADGRG3 mRNA CTD PMID:33647349 NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 decreases expression ISO licochalcone B results in decreased expression of ADGRL2 mRNA CTD PMID:33647349 NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141
JBrowse link
G Adm adrenomedullin increases expression ISO licochalcone B results in increased expression of ADM mRNA CTD PMID:33647349 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adra1d adrenoceptor alpha 1D increases expression ISO licochalcone B results in increased expression of ADRA1D mRNA CTD PMID:33647349 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Adra2b adrenoceptor alpha 2B increases expression ISO licochalcone B results in increased expression of ADRA2B mRNA CTD PMID:33647349 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression ISO licochalcone B results in increased expression of ADRB2 mRNA CTD PMID:33647349 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Afmid arylformamidase increases expression ISO licochalcone B results in increased expression of AFMID mRNA CTD PMID:33647349 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase decreases expression ISO licochalcone B results in decreased expression of AGL mRNA CTD PMID:33647349 NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
JBrowse link
G Akap5 A-kinase anchoring protein 5 decreases expression ISO licochalcone B results in decreased expression of AKAP5 mRNA CTD PMID:33647349 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO licochalcone B results in increased expression of AKR1B10 mRNA CTD PMID:33647349 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO licochalcone B results in increased expression of ALDH1A1 mRNA CTD PMID:33647349 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alg9 ALG9, alpha-1,2-mannosyltransferase decreases expression ISO licochalcone B results in decreased expression of ALG9 mRNA CTD PMID:33647349 NCBI chr 8:51,117,057...51,188,790
Ensembl chr 8:51,119,365...51,182,261
JBrowse link
G Alkal2 ALK and LTK ligand 2 increases expression ISO licochalcone B results in increased expression of ALKAL2 mRNA CTD PMID:33647349 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO licochalcone B results in increased expression of ALOX12 mRNA CTD PMID:33647349 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 increases expression ISO licochalcone B results in increased expression of ALOXE3 mRNA CTD PMID:33647349 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328
JBrowse link
G Ang angiogenin decreases expression ISO licochalcone B results in decreased expression of ANG mRNA CTD PMID:33647349 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO licochalcone B results in increased expression of ANKRD1 mRNA CTD PMID:33647349 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO licochalcone B results in increased expression of AP3B2 mRNA CTD PMID:33647349 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 increases expression ISO licochalcone B results in increased expression of AP5Z1 mRNA CTD PMID:33647349 NCBI chr12:12,093,834...12,109,043 JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 increases expression ISO licochalcone B results in increased expression of APBB1 mRNA CTD PMID:33647349 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627
JBrowse link
G Apobr apolipoprotein B receptor decreases expression ISO licochalcone B results in decreased expression of APOBR mRNA CTD PMID:33647349 NCBI chr 1:181,168,982...181,173,528
Ensembl chr 1:181,168,916...181,173,528
JBrowse link
G Apoe apolipoprotein E increases expression ISO licochalcone B results in increased expression of APOE mRNA CTD PMID:33647349 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO licochalcone B results in increased expression of ARC mRNA CTD PMID:33647349 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arhgef33 Rho guanine nucleotide exchange factor 33 increases expression ISO licochalcone B results in increased expression of ARHGEF33 mRNA CTD PMID:33647349 NCBI chr 6:14,582,922...14,715,014
Ensembl chr 6:14,551,495...14,725,292
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases expression ISO licochalcone B results in increased expression of ARL4C mRNA CTD PMID:33647349 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D increases expression ISO licochalcone B results in increased expression of ARL4D mRNA CTD PMID:33647349 NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 increases expression ISO licochalcone B results in increased expression of ARL6IP4 mRNA CTD PMID:33647349 NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression ISO licochalcone B results in decreased expression of ARNT2 mRNA CTD PMID:33647349 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Arpin actin-related protein 2/3 complex inhibitor decreases expression ISO licochalcone B results in decreased expression of ARPIN mRNA CTD PMID:33647349 NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124
JBrowse link
G Asic4 acid sensing ion channel subunit family member 4 increases expression ISO licochalcone B results in increased expression of ASIC4 mRNA CTD PMID:33647349 NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO licochalcone B results in increased expression of ASNS mRNA CTD PMID:33647349 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atcay ATCAY kinesin light chain interacting caytaxin increases expression ISO licochalcone B results in increased expression of ATCAY mRNA CTD PMID:33647349 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO licochalcone B results in increased expression of ATF3 mRNA CTD PMID:33647349 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atg9b autophagy related 9B increases expression ISO licochalcone B results in increased expression of ATG9B mRNA CTD PMID:33647349 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
JBrowse link
G Atp13a4 ATPase 13A4 increases expression ISO licochalcone B results in increased expression of ATP13A4 mRNA CTD PMID:33647349 NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression ISO licochalcone B results in increased expression of ATP1A3 mRNA CTD PMID:33647349 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression ISO licochalcone B results in increased expression of ATP6V0C mRNA CTD PMID:33647349 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) decreases expression ISO licochalcone B results in decreased expression of ATP9A mRNA CTD PMID:33647349 NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
JBrowse link
G Aurkc aurora kinase C increases expression ISO licochalcone B results in increased expression of AURKC mRNA CTD PMID:33647349 NCBI chr 1:66,843,653...66,864,348
Ensembl chr 1:66,843,653...66,864,386
JBrowse link
G B3gnt4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 increases expression ISO licochalcone B results in increased expression of B3GNT4 mRNA CTD PMID:33647349 NCBI chr12:33,070,221...33,073,904
Ensembl chr12:33,060,416...33,073,854
JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 increases expression ISO licochalcone B results in increased expression of B4GALNT3 mRNA CTD PMID:33647349 NCBI chr 4:153,410,907...153,509,019
Ensembl chr 4:153,409,004...153,509,321
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO licochalcone B results in increased expression of BAG3 mRNA CTD PMID:33647349 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression ISO licochalcone B results in increased expression of BAIAP2 mRNA CTD PMID:33647349 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO licochalcone B results in increased expression of BAIAP3 mRNA CTD PMID:33647349 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO licochalcone B results in increased expression of BAMBI mRNA CTD PMID:33647349 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO licochalcone B results in increased expression of BAX protein CTD PMID:24384411 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO licochalcone B results in increased expression of BBC3 mRNA CTD PMID:33647349 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO licochalcone B results in decreased expression of BCL2 protein CTD PMID:24384411 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bex2 brain expressed X-linked 2 increases expression ISO licochalcone B results in increased expression of BEX2 mRNA CTD PMID:33647349 NCBI chr  X:99,019,847...99,021,375
Ensembl chr  X:99,019,000...99,021,503
JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 increases expression ISO licochalcone B results in increased expression of BICDL2 mRNA CTD PMID:33647349 NCBI chr10:12,691,610...12,700,049
Ensembl chr10:12,691,610...12,700,049
JBrowse link
G Bik BCL2-interacting killer increases expression ISO licochalcone B results in increased expression of BIK mRNA CTD PMID:33647349 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO licochalcone B results in decreased expression of BIRC5 protein CTD PMID:24384411 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO licochalcone B results in increased expression of BLVRB mRNA CTD PMID:33647349 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bmper BMP-binding endothelial regulator decreases expression ISO licochalcone B results in decreased expression of BMPER mRNA CTD PMID:33647349 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO licochalcone B results in increased expression of BPGM mRNA CTD PMID:33647349 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator increases expression ISO licochalcone B results in increased expression of BRMS1 mRNA CTD PMID:33647349 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 increases expression ISO licochalcone B results in increased expression of BST1 mRNA CTD PMID:33647349 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180
JBrowse link
G Btbd8 BTB domain containing 8 decreases expression ISO licochalcone B results in decreased expression of BTBD8 mRNA CTD PMID:33647349 NCBI chr14:2,265,189...2,338,426
Ensembl chr14:2,266,454...2,334,393
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO licochalcone B results in increased expression of BTG2 mRNA CTD PMID:33647349 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Btla B and T lymphocyte associated increases expression ISO licochalcone B results in increased expression of BTLA mRNA CTD PMID:33647349 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181
JBrowse link
G C12H7orf61 chromosome 12 open reading frame, human C7orf61 increases expression ISO licochalcone B results in increased expression of C7ORF61 mRNA CTD PMID:33647349 NCBI chr12:18,930,608...18,936,787 JBrowse link
G C1H10orf95 chromosome 1 C10orf95 homolog decreases expression ISO licochalcone B results in decreased expression of C10ORF95 mRNA CTD PMID:33647349 NCBI chr 1:245,210,228...245,212,080 JBrowse link
G C1ql3 complement C1q like 3 increases expression ISO licochalcone B results in increased expression of C1QL3 mRNA CTD PMID:33647349 NCBI chr17:76,121,832...76,128,327
Ensembl chr17:76,119,447...76,128,530
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression ISO licochalcone B results in increased expression of C1QTNF4 mRNA CTD PMID:33647349 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G C5ar2 complement C5a receptor 2 decreases expression ISO licochalcone B results in decreased expression of C5AR2 mRNA CTD PMID:33647349 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517
JBrowse link
G Cabp7 calcium binding protein 7 increases expression ISO licochalcone B results in increased expression of CABP7 mRNA CTD PMID:33647349 NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 increases expression ISO licochalcone B results in increased expression of CACNA2D2 mRNA CTD PMID:33647349 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 decreases expression ISO licochalcone B results in decreased expression of CACNB2 mRNA CTD PMID:33647349 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link
G Calb2 calbindin 2 increases expression ISO licochalcone B results in increased expression of CALB2 mRNA CTD PMID:33647349 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO licochalcone B results in increased expression of CARD9 mRNA CTD PMID:33647349 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Carf calcium responsive transcription factor decreases expression ISO licochalcone B results in decreased expression of CARF mRNA CTD PMID:33647349 NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462
JBrowse link
G Casp14 caspase 14 decreases expression ISO licochalcone B results in decreased expression of CASP14 mRNA CTD PMID:33647349 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Casp3 caspase 3 increases activity ISO licochalcone B results in increased activity of CASP3 protein CTD PMID:24384411 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cass4 Cas scaffold protein family member 4 increases expression ISO licochalcone B results in increased expression of CASS4 mRNA CTD PMID:33647349 NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186
JBrowse link
G Catsperg cation channel sperm associated auxiliary subunit gamma increases expression ISO licochalcone B results in increased expression of CATSPERG mRNA CTD PMID:33647349 NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression ISO licochalcone B results in increased expression of CBARP mRNA CTD PMID:33647349 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Cbx4 chromobox 4 increases expression ISO licochalcone B results in increased expression of CBX4 mRNA CTD PMID:33647349 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Ccdc13 coiled-coil domain containing 13 increases expression ISO licochalcone B results in increased expression of CCDC13 mRNA CTD PMID:33647349 NCBI chr 8:121,455,202...121,507,487
Ensembl chr 8:121,457,697...121,502,337
JBrowse link
G Ccdc148 coiled-coil domain containing 148 increases expression ISO licochalcone B results in increased expression of CCDC148 mRNA CTD PMID:33647349 NCBI chr 3:43,356,885...43,631,999
Ensembl chr 3:43,356,892...43,631,991
JBrowse link
G Ccdc194 coiled-coil domain containing 194 increases expression ISO licochalcone B results in increased expression of CCDC194 mRNA CTD PMID:33647349 NCBI chr16:18,205,099...18,209,310 JBrowse link
G Ccdc68 coiled-coil domain containing 68 decreases expression ISO licochalcone B results in decreased expression of CCDC68 mRNA CTD PMID:33647349 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119
JBrowse link
G Ccdc9 coiled-coil domain containing 9 increases expression ISO licochalcone B results in increased expression of CCDC9 mRNA CTD PMID:33647349 NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression ISO licochalcone B results in increased expression of CCDC96 mRNA CTD PMID:33647349 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
JBrowse link
G Ccm2l CCM2 like scaffold protein increases expression ISO licochalcone B results in increased expression of CCM2L mRNA CTD PMID:33647349 NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO licochalcone B results in increased expression of CCN1 mRNA CTD PMID:33647349 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO licochalcone B results in increased expression of CCN2 mRNA CTD PMID:33647349 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO licochalcone B results in decreased expression of CCNA2 mRNA CTD PMID:24384411 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccne1 cyclin E1 increases expression ISO licochalcone B results in increased expression of CCNE1 mRNA CTD PMID:33647349 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd14 CD14 molecule increases expression ISO licochalcone B results in increased expression of CD14 mRNA CTD PMID:33647349 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd247 Cd247 molecule increases expression ISO licochalcone B results in increased expression of CD247 mRNA CTD PMID:33647349 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd27 CD27 molecule increases expression ISO licochalcone B results in increased expression of CD27 mRNA CTD PMID:33647349 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd4 Cd4 molecule increases expression ISO licochalcone B results in increased expression of CD4 mRNA CTD PMID:33647349 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd79a CD79a molecule increases expression ISO licochalcone B results in increased expression of CD79A mRNA CTD PMID:33647349 NCBI chr 1:80,493,520...80,497,936
Ensembl chr 1:80,493,581...80,497,935
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO licochalcone B results in decreased expression of CDC25A protein CTD PMID:24384411 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO licochalcone B results in decreased expression of CDC25B protein CTD PMID:24384411 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme increases expression ISO licochalcone B results in increased expression of CDC34 mRNA CTD PMID:33647349 NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 increases expression ISO licochalcone B results in increased expression of CDC42EP2 mRNA CTD PMID:33647349 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdh23 cadherin-related 23 increases expression ISO licochalcone B results in increased expression of CDH23 mRNA CTD PMID:33647349 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO licochalcone B results in decreased expression of CDK1 mRNA CTD PMID:24384411 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO licochalcone B results in decreased expression of CDK2 mRNA CTD PMID:24384411 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 increases expression ISO licochalcone B results in increased expression of CDK2AP2 mRNA CTD PMID:33647349 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO licochalcone B results in increased expression of CDK5R1 mRNA CTD PMID:33647349 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 decreases expression ISO licochalcone B results in decreased expression of CDK5R2 mRNA CTD PMID:33647349 NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO licochalcone B results in increased expression of CDKN1A mRNA CTD PMID:33647349 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO licochalcone B results in increased expression of CDKN1C mRNA CTD PMID:33647349 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D increases expression ISO licochalcone B results in increased expression of CDKN2D mRNA CTD PMID:33647349 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Celf5 CUGBP, Elav-like family member 5 increases expression ISO licochalcone B results in increased expression of CELF5 mRNA CTD PMID:33647349 NCBI chr 7:8,225,787...8,250,322
Ensembl chr 7:8,225,825...8,250,322
JBrowse link
G Cenpe centromere protein E decreases expression ISO licochalcone B results in decreased expression of CENPE mRNA CTD PMID:33647349 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cfap20 cilia and flagella associated protein 20 increases expression ISO licochalcone B results in increased expression of CFAP20 mRNA CTD PMID:33647349 NCBI chr19:9,608,851...9,622,562
Ensembl chr19:9,608,859...9,622,558
JBrowse link
G Cfap43 cilia and flagella associated protein 43 increases expression ISO licochalcone B results in increased expression of CFAP43 mRNA CTD PMID:33647349 NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443
JBrowse link
G Cfap99 cilia and flagella associated protein 99 increases expression ISO licochalcone B results in increased expression of CFAP99 mRNA CTD PMID:33647349 NCBI chr14:76,423,923...76,468,170
Ensembl chr14:76,410,555...76,468,125
JBrowse link
G Cfp complement factor properdin increases expression ISO licochalcone B results in increased expression of CFP mRNA CTD PMID:33647349 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO licochalcone B results in increased expression of CHAC1 mRNA CTD PMID:33647349 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 increases expression ISO licochalcone B results in increased expression of CHCHD7 mRNA CTD PMID:33647349 NCBI chr 5:16,957,081...16,969,388
Ensembl chr 5:16,957,188...16,961,184
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression ISO licochalcone B results in decreased expression of CHRM3 mRNA CTD PMID:33647349 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 increases expression ISO licochalcone B results in increased expression of CHRM4 mRNA CTD PMID:33647349 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit increases expression ISO licochalcone B results in increased expression of CHRNA3 mRNA CTD PMID:33647349 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression ISO licochalcone B results in increased expression of CHRNA7 mRNA CTD PMID:33647349 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit decreases expression ISO licochalcone B results in decreased expression of CHRND mRNA CTD PMID:33647349 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit decreases expression ISO licochalcone B results in decreased expression of CHRNG mRNA CTD PMID:33647349 NCBI chr 9:87,878,085...87,884,193 JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO licochalcone B results in increased expression of CITED2 mRNA CTD PMID:33647349 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO licochalcone B results in increased expression of CKS2 mRNA CTD PMID:33647349 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn19 claudin 19 increases expression ISO licochalcone B results in increased expression of CLDN19 mRNA CTD PMID:33647349 NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227
JBrowse link
G Cldn6 claudin 6 increases expression ISO licochalcone B results in increased expression of CLDN6 mRNA CTD PMID:33647349 NCBI chr10:12,710,302...12,713,987 JBrowse link
G Cldn9 claudin 9 increases expression ISO licochalcone B results in increased expression of CLDN9 mRNA CTD PMID:33647349 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Clu clusterin increases expression ISO licochalcone B results in increased expression of CLU mRNA CTD PMID:33647349 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 increases expression ISO licochalcone B results in increased expression of CNIH3 mRNA CTD PMID:33647349 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 increases expression ISO licochalcone B results in increased expression of CNNM4 mRNA CTD PMID:33647349 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942
JBrowse link
G Cntn2 contactin 2 increases expression ISO licochalcone B results in increased expression of CNTN2 mRNA CTD PMID:33647349 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO licochalcone B results in increased expression of COL6A2 mRNA CTD PMID:33647349 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Cox8c cytochrome c oxidase subunit 8C increases expression ISO licochalcone B results in increased expression of COX8C mRNA CTD PMID:33647349 NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889
JBrowse link
G Cplx2 complexin 2 increases expression ISO licochalcone B results in increased expression of CPLX2 mRNA CTD PMID:33647349 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression ISO licochalcone B results in decreased expression of CPS1 mRNA CTD PMID:33647349 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression ISO licochalcone B results in decreased expression of CRISPLD1 mRNA CTD PMID:33647349 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO licochalcone B results in increased expression of CRISPLD2 mRNA CTD PMID:33647349 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
JBrowse link
G Cryba1 crystallin, beta A1 increases expression ISO licochalcone B results in increased expression of CRYBA1 mRNA CTD PMID:33647349 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726
JBrowse link
G Crybg1 crystallin beta-gamma domain containing 1 decreases expression ISO licochalcone B results in decreased expression of CRYBG1 mRNA CTD PMID:33647349 NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392
JBrowse link
G Crym crystallin, mu increases expression ISO licochalcone B results in increased expression of CRYM mRNA CTD PMID:33647349 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO licochalcone B results in increased expression of CSRNP1 mRNA CTD PMID:33647349 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Csrnp2 cysteine and serine rich nuclear protein 2 increases expression ISO licochalcone B results in increased expression of CSRNP2 mRNA CTD PMID:33647349 NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO licochalcone B results in increased expression of CSRP2 mRNA CTD PMID:33647349 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Ctrc chymotrypsin C increases expression ISO licochalcone B results in increased expression of CTRC mRNA CTD PMID:33647349 NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528
JBrowse link
G Cxxc4 CXXC finger protein 4 decreases expression ISO licochalcone B results in decreased expression of CXXC4 mRNA CTD PMID:33647349 NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365
JBrowse link
G Cygb cytoglobin decreases expression ISO licochalcone B results in decreased expression of CYGB mRNA CTD PMID:33647349 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO licochalcone B results in increased expression of CYP27A1 mRNA CTD PMID:33647349 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 increases expression ISO licochalcone B results in increased expression of DACT3 mRNA CTD PMID:33647349 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase increases expression ISO licochalcone B results in increased expression of DCXR mRNA CTD PMID:33647349 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO licochalcone B results in increased expression of DDIT3 mRNA CTD PMID:33647349 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 increases expression ISO licochalcone B results in increased expression of DDR2 mRNA CTD PMID:33647349 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Dedd2 death effector domain containing 2 increases expression ISO licochalcone B results in increased expression of DEDD2 mRNA CTD PMID:33647349 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO licochalcone B results in increased expression of DGAT1 mRNA CTD PMID:33647349 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhdh dihydrodiol dehydrogenase increases expression ISO licochalcone B results in increased expression of DHDH mRNA CTD PMID:33647349 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197
JBrowse link
G Dhx58 DEXH-box helicase 58 increases expression ISO licochalcone B results in increased expression of DHX58 mRNA CTD PMID:33647349 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO licochalcone B results in decreased expression of DIO2 mRNA CTD PMID:33647349 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 increases expression ISO licochalcone B results in increased expression of DIO3 mRNA CTD PMID:33647349 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Disp3 dispatched RND transporter family member 3 increases expression ISO licochalcone B results in increased expression of DISP3 mRNA CTD PMID:33647349 NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:158,672,015...158,720,806
JBrowse link
G Dixdc1 DIX domain containing 1 decreases expression ISO licochalcone B results in decreased expression of DIXDC1 mRNA CTD PMID:33647349 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 decreases expression ISO licochalcone B results in decreased expression of DLG3 mRNA CTD PMID:33647349 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322
JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression ISO licochalcone B results in increased expression of DLL4 mRNA CTD PMID:33647349 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO licochalcone B results in increased expression of DLX2 mRNA CTD PMID:33647349 NCBI chr 3:56,371,347...56,373,230
Ensembl chr 3:56,370,483...56,373,597
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 decreases expression ISO licochalcone B results in decreased expression of DMBT1 mRNA CTD PMID:33647349 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 increases expression ISO licochalcone B results in increased expression of DNAH3 mRNA CTD PMID:33647349 NCBI chr 1:174,305,929...174,479,490 JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 increases expression ISO licochalcone B results in increased expression of DNAJA4 mRNA CTD PMID:33647349 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO licochalcone B results in increased expression of DNAJB1 mRNA CTD PMID:33647349 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajc28 DnaJ heat shock protein family (Hsp40) member C28 decreases expression ISO licochalcone B results in decreased expression of DNAJC28 mRNA CTD PMID:33647349 NCBI chr11:30,855,566...30,858,386
Ensembl chr11:30,853,526...30,858,441
JBrowse link
G Dock3 dedicator of cyto-kinesis 3 increases expression ISO licochalcone B results in increased expression of DOCK3 mRNA CTD PMID:33647349 NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514
JBrowse link
G Drap1 Dr1 associated protein 1 increases expression ISO licochalcone B results in increased expression of DRAP1 mRNA CTD PMID:33647349 NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425
JBrowse link
G Drc1 dynein regulatory complex subunit 1 increases expression ISO licochalcone B results in increased expression of DRC1 mRNA CTD PMID:33647349 NCBI chr 6:26,025,004...26,059,438
Ensembl chr 6:26,025,005...26,059,414
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO licochalcone B results in decreased expression of DTX3L mRNA CTD PMID:33647349 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO licochalcone B results in increased expression of DUSP2 mRNA CTD PMID:33647349 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO licochalcone B results in increased expression of DUSP5 mRNA CTD PMID:33647349 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp7 dual specificity phosphatase 7 increases expression ISO licochalcone B results in increased expression of DUSP7 mRNA CTD PMID:33647349 NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
JBrowse link
G Eddm13 epididymal protein 13 decreases expression ISO licochalcone B results in decreased expression of EDDM13 mRNA CTD PMID:33647349 NCBI chr 1:67,630,905...67,656,404 JBrowse link
G Ednra endothelin receptor type A decreases expression ISO licochalcone B results in decreased expression of EDNRA mRNA CTD PMID:33647349 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Efnb2 ephrin B2 increases expression ISO licochalcone B results in increased expression of EFNB2 mRNA CTD PMID:33647349 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Efnb3 ephrin B3 increases expression ISO licochalcone B results in increased expression of EFNB3 mRNA CTD PMID:33647349 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471
JBrowse link
G Egfl8 EGF-like-domain, multiple 8 decreases expression ISO licochalcone B results in decreased expression of EGFL8 mRNA CTD PMID:33647349 NCBI chr20:4,132,930...4,136,024
Ensembl chr20:4,133,629...4,136,018
JBrowse link
G Egr1 early growth response 1 increases expression ISO licochalcone B results in increased expression of EGR1 mRNA CTD PMID:33647349 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr3 early growth response 3 increases expression ISO licochalcone B results in increased expression of EGR3 mRNA CTD PMID:33647349 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Ehd1 EH-domain containing 1 increases expression ISO licochalcone B results in increased expression of EHD1 mRNA CTD PMID:33647349 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
JBrowse link
G Ehf ets homologous factor decreases expression ISO licochalcone B results in decreased expression of EHF mRNA CTD PMID:33647349 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO licochalcone B results in increased expression of EIF4A1 mRNA CTD PMID:33647349 NCBI chr10:54,384,345...54,389,853
Ensembl chr10:54,384,347...54,389,858
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 increases expression ISO licochalcone B results in increased expression of EIF4A3 mRNA CTD PMID:33647349 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Emc9 ER membrane protein complex subunit 9 increases expression ISO licochalcone B results in increased expression of EMC9 mRNA CTD PMID:33647349 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098
JBrowse link
G Engase endo-beta-N-acetylglucosaminidase increases expression ISO licochalcone B results in increased expression of ENGASE mRNA CTD PMID:33647349 NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819
JBrowse link
G Epha2 Eph receptor A2 increases expression ISO licochalcone B results in increased expression of EPHA2 mRNA CTD PMID:33647349 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Epha3 Eph receptor A3 decreases expression ISO licochalcone B results in decreased expression of EPHA3 mRNA CTD PMID:33647349 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Eppk1 epiplakin 1 increases expression ISO licochalcone B results in increased expression of EPPK1 mRNA CTD PMID:33647349 NCBI chr 7:107,816,919...107,842,946 JBrowse link
G Eras ES cell expressed Ras increases expression ISO licochalcone B results in increased expression of ERAS mRNA CTD PMID:33647349 NCBI chr  X:14,573,987...14,578,455
Ensembl chr  X:14,573,987...14,578,374
JBrowse link
G Erf Ets2 repressor factor increases expression ISO licochalcone B results in increased expression of ERF mRNA CTD PMID:33647349 NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388
JBrowse link
G Erlin2 ER lipid raft associated 2 decreases expression ISO licochalcone B results in decreased expression of ERLIN2 mRNA CTD PMID:33647349 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Espn espin increases expression ISO licochalcone B results in increased expression of ESPN mRNA CTD PMID:33647349 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
JBrowse link
G Eva1b eva-1 homolog B increases expression ISO licochalcone B results in increased expression of EVA1B mRNA CTD PMID:33647349 NCBI chr 5:138,427,083...138,429,602
Ensembl chr 5:138,427,151...138,432,433
JBrowse link
G Exoc3l2 exocyst complex component 3-like 2 increases expression ISO licochalcone B results in increased expression of EXOC3L2 mRNA CTD PMID:33647349 NCBI chr 1:79,113,784...79,145,359
Ensembl chr 1:79,112,506...79,145,465
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO licochalcone B results in decreased expression of F2R mRNA CTD PMID:33647349 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fam102a family with sequence similarity 102, member A increases expression ISO licochalcone B results in increased expression of FAM102A mRNA CTD PMID:33647349 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643
JBrowse link
G Fam117a family with sequence similarity 117, member A increases expression ISO licochalcone B results in increased expression of FAM117A mRNA CTD PMID:33647349 NCBI chr10:80,281,408...80,325,343
Ensembl chr10:80,281,408...80,325,343
JBrowse link
G Fam166a family with sequence similarity 166, member A increases expression ISO licochalcone B results in increased expression of FAM166A mRNA CTD PMID:33647349 NCBI chr 3:8,030,548...8,038,370
Ensembl chr 3:8,033,246...8,037,961
JBrowse link
G Fam205a family with sequence similarity 205, member A increases expression ISO licochalcone B results in increased expression of FAM205A mRNA CTD PMID:33647349 NCBI chr 5:57,065,739...57,071,880
Ensembl chr 5:57,065,747...57,071,738
JBrowse link
G Fam222a family with sequence similarity 222, member A increases expression ISO licochalcone B results in increased expression of FAM222A mRNA CTD PMID:33647349 NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682
JBrowse link
G Fam228b family with sequence similarity 228, member B increases expression ISO licochalcone B results in increased expression of FAM228B mRNA CTD PMID:33647349 NCBI chr 6:27,754,505...27,786,578
Ensembl chr 6:27,754,506...27,786,537
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO licochalcone B results in increased expression of FAM43A mRNA CTD PMID:33647349 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
JBrowse link
G Fam78a family with sequence similarity 78, member A decreases expression ISO licochalcone B results in decreased expression of FAM78A mRNA CTD PMID:33647349 NCBI chr 3:15,355,958...15,376,330
Ensembl chr 3:15,355,955...15,373,812
JBrowse link
G Fam89b family with sequence similarity 89, member B increases expression ISO licochalcone B results in increased expression of FAM89B mRNA CTD PMID:33647349 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 increases expression ISO licochalcone B results in increased expression of FAM90A1 mRNA CTD PMID:33647349 NCBI chr16:70,098,439...70,106,147 JBrowse link
G Fbll1 fibrillarin-like 1 increases expression ISO licochalcone B results in increased expression of FBLL1 mRNA CTD PMID:33647349 NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO licochalcone B results in increased expression of FBXO32 mRNA CTD PMID:33647349 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fcgbp Fc fragment of IgG binding protein increases expression ISO licochalcone B results in increased expression of FCGBP mRNA CTD PMID:33647349 NCBI chr 1:83,374,979...83,413,083
Ensembl chr 1:83,372,127...83,413,083
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia increases expression ISO licochalcone B results in increased expression of FCGR1A mRNA CTD PMID:33647349 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fer1l5 fer-1-like family member 5 increases expression ISO licochalcone B results in increased expression of FER1L5 mRNA CTD PMID:33647349 NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425
JBrowse link
G Fgf18 fibroblast growth factor 18 increases expression ISO licochalcone B results in increased expression of FGF18 mRNA CTD PMID:33647349 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf22 fibroblast growth factor 22 increases expression ISO licochalcone B results in increased expression of FGF22 mRNA CTD PMID:33647349 NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO licochalcone B results in increased expression of FGFR3 mRNA CTD PMID:33647349 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fitm1 fat storage-inducing transmembrane protein 1 increases expression ISO licochalcone B results in increased expression of FITM1 mRNA CTD PMID:33647349 NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO licochalcone B results in increased expression of FOS mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of FOS protein]
CTD PMID:25451593 PMID:33647349 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO licochalcone B results in increased expression of FOSB mRNA CTD PMID:33647349 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO licochalcone B results in increased expression of FOSL1 mRNA CTD PMID:33647349 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxa3 forkhead box A3 increases expression ISO licochalcone B results in increased expression of FOXA3 mRNA CTD PMID:33647349 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxd1 forkhead box D1 increases expression ISO licochalcone B results in increased expression of FOXD1 mRNA CTD PMID:33647349 NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978
JBrowse link
G Foxe3 forkhead box E3 increases expression ISO licochalcone B results in increased expression of FOXE3 mRNA CTD PMID:33647349 NCBI chr 5:128,445,594...128,446,454
Ensembl chr 5:128,445,594...128,446,454
JBrowse link
G Foxp4 forkhead box P4 increases expression ISO licochalcone B results in increased expression of FOXP4 mRNA CTD PMID:33647349 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879
JBrowse link
G Frg2 FSHD region gene 2 increases expression ISO licochalcone B results in increased expression of FRG2 mRNA CTD PMID:33647349 NCBI chr14:80,427,260...80,429,560
Ensembl chr14:80,427,673...80,429,181
JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO licochalcone B results in decreased expression of FRY mRNA CTD PMID:33647349 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
JBrowse link
G Frzb frizzled-related protein increases expression ISO licochalcone B results in increased expression of FRZB mRNA CTD PMID:33647349 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO licochalcone B results in decreased expression of FUT1 mRNA CTD PMID:33647349 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 decreases expression ISO licochalcone B results in decreased expression of FYCO1 mRNA CTD PMID:33647349 NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021
JBrowse link
G Fzd7 frizzled class receptor 7 increases expression ISO licochalcone B results in increased expression of FZD7 mRNA CTD PMID:33647349 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 increases expression ISO licochalcone B results in increased expression of GABRR2 mRNA CTD PMID:33647349 NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO licochalcone B results in increased expression of GADD45A mRNA CTD PMID:33647349 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO licochalcone B results in increased expression of GADD45B mRNA CTD PMID:33647349 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Galntl6 polypeptide N-acetylgalactosaminyltransferase-like 6 decreases expression ISO licochalcone B results in decreased expression of GALNTL6 mRNA CTD PMID:33647349 NCBI chr16:31,192,880...32,443,979
Ensembl chr16:31,186,462...32,441,960
JBrowse link
G Galr2 galanin receptor 2 increases expression ISO licochalcone B results in increased expression of GALR2 mRNA CTD PMID:33647349 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Gata2 GATA binding protein 2 increases expression ISO licochalcone B results in increased expression of GATA2 mRNA CTD PMID:33647349 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gata3 GATA binding protein 3 increases expression ISO licochalcone B results in increased expression of GATA3 mRNA CTD PMID:33647349 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gbx2 gastrulation brain homeobox 2 increases expression ISO licochalcone B results in increased expression of GBX2 mRNA CTD PMID:33647349 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Gcm1 glial cells missing transcription factor 1 increases expression ISO licochalcone B results in increased expression of GCM1 mRNA CTD PMID:33647349 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO licochalcone B results in increased expression of GEM mRNA CTD PMID:33647349 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Get4 guided entry of tail-anchored proteins factor 4 increases expression ISO licochalcone B results in increased expression of GET4 mRNA CTD PMID:33647349 NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO licochalcone B results in decreased expression of GFI1 mRNA CTD PMID:33647349 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO licochalcone B results in increased expression of GFPT2 mRNA CTD PMID:33647349 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
JBrowse link
G Gfra3 GDNF family receptor alpha 3 increases expression ISO licochalcone B results in increased expression of GFRA3 mRNA CTD PMID:33647349 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 increases expression ISO licochalcone B results in increased expression of GIPC2 mRNA CTD PMID:33647349 NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
JBrowse link
G Gng13 G protein subunit gamma 13 increases expression ISO licochalcone B results in increased expression of GNG13 mRNA CTD PMID:33647349 NCBI chr10:14,741,179...14,743,083
Ensembl chr10:14,741,239...14,743,083
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression ISO licochalcone B results in increased expression of GSTM5 mRNA CTD PMID:33647349 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gzmm granzyme M increases expression ISO licochalcone B results in increased expression of GZMM mRNA CTD PMID:33647349 NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665
JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO licochalcone B results in increased expression of H1-4 mRNA CTD PMID:33647349 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H2ac12 H2A clustered histone 12 increases expression ISO licochalcone B results in increased expression of H2AC12 mRNA CTD PMID:33647349 NCBI chr17:42,486,315...42,486,880 JBrowse link
G H2ac21 H2A clustered histone 21 increases expression ISO licochalcone B results in increased expression of H2AC21 mRNA CTD PMID:33647349 NCBI chr 2:183,779,385...183,779,777 JBrowse link
G H2ax H2A.X variant histone increases expression ISO licochalcone B results in increased expression of H2AX mRNA CTD PMID:33647349 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO licochalcone B results in increased expression of H2BC12 mRNA CTD PMID:33647349 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H2bc9 H2B clustered histone 9 increases expression ISO licochalcone B results in increased expression of H2BC9 mRNA CTD PMID:33647349 NCBI chr17:42,470,593...42,478,605 JBrowse link
G H3c1 H3 clustered histone 1 increases expression ISO licochalcone B results in increased expression of H3C1 mRNA CTD PMID:33647349 NCBI chr17:41,367,824...41,368,902 JBrowse link
G H3c13 H3 clustered histone 13 increases expression ISO licochalcone B results in increased expression of H3C13 mRNA CTD PMID:33647349 NCBI chr17:41,529,860...41,532,577 JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO licochalcone B results in increased expression of H4C3 mRNA CTD PMID:33647349
G Hamp hepcidin antimicrobial peptide increases expression ISO licochalcone B results in increased expression of HAMP mRNA CTD PMID:33647349 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 increases expression ISO licochalcone B results in increased expression of HAPLN2 mRNA CTD PMID:33647349 NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression ISO licochalcone B results in increased expression of HAPLN3 mRNA CTD PMID:33647349 NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO licochalcone B results in increased expression of HAS1 mRNA CTD PMID:33647349 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Has3 hyaluronan synthase 3 increases expression ISO licochalcone B results in increased expression of HAS3 mRNA CTD PMID:33647349 NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression ISO licochalcone B results in increased expression of HBA1 mRNA CTD PMID:33647349 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO licochalcone B results in increased expression of HBEGF mRNA CTD PMID:33647349 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO licochalcone B results in increased expression of HERPUD1 mRNA CTD PMID:33647349 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes6 hes family bHLH transcription factor 6 increases expression ISO licochalcone B results in increased expression of HES6 mRNA CTD PMID:33647349 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hes7 hes family bHLH transcription factor 7 increases expression ISO licochalcone B results in increased expression of HES7 mRNA CTD PMID:33647349 NCBI chr10:53,824,124...53,828,350
Ensembl chr10:53,825,574...53,828,097
JBrowse link
G Hic2 HIC ZBTB transcriptional repressor 2 increases expression ISO licochalcone B results in increased expression of HIC2 mRNA CTD PMID:33647349 NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 increases expression ISO licochalcone B results in increased expression of HIPK4 mRNA CTD PMID:33647349 NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO licochalcone B results in increased expression of H2AC8 mRNA CTD PMID:33647349 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO licochalcone B results in increased expression of H2BC5 mRNA CTD PMID:33647349 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l increases expression ISO licochalcone B results in increased expression of H2BC8 mRNA CTD PMID:33647349 NCBI chr17:42,708,646...42,709,435 JBrowse link
G Hist1h2bo histone cluster 1 H2B family member o increases expression ISO licochalcone B results in increased expression of H2BC17 mRNA CTD PMID:33647349 NCBI chr17:42,716,433...42,718,046
Ensembl chr17:42,673,067...42,718,095
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q increases expression ISO licochalcone B results in increased expression of H2BC7 mRNA CTD PMID:33647349 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B increases expression ISO licochalcone B results in increased expression of H4C9 mRNA CTD PMID:33647349 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
JBrowse link
G Hist1h4m histone cluster 1, H4m increases expression ISO licochalcone B results in increased expression of H4C1 mRNA CTD PMID:33647349 NCBI chr17:42,698,054...42,698,365
Ensembl chr17:42,698,025...42,698,958
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E increases expression ISO licochalcone B results in increased expression of H2BC11 mRNA CTD PMID:33647349 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hist2h4a histone cluster 2 H4 family member A increases expression ISO licochalcone B results in increased expression of H4C4 mRNA CTD PMID:33647349
G Hmox1 heme oxygenase 1 increases expression ISO licochalcone B results in increased expression of HMOX1 mRNA CTD PMID:33647349 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer2 homer scaffold protein 2 increases expression ISO licochalcone B results in increased expression of HOMER2 mRNA CTD PMID:33647349 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Hoxc4 homeo box C4 decreases expression ISO licochalcone B results in decreased expression of HOXC4 mRNA CTD PMID:33647349 NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133
JBrowse link
G Hpx hemopexin increases expression ISO licochalcone B results in increased expression of HPX mRNA CTD PMID:33647349 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO licochalcone B results in increased expression of HSPA1A mRNA CTD PMID:33647349
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO licochalcone B results in increased expression of HSPA1B mRNA CTD PMID:33647349 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression ISO licochalcone B results in increased expression of HSPA1L mRNA CTD PMID:33647349 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO licochalcone B results in increased expression of HSPA8 mRNA CTD PMID:33647349 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression ISO licochalcone B results in increased expression of HSPB8 mRNA CTD PMID:33647349 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hspb9 heat shock protein family B (small) member 9 increases expression ISO licochalcone B results in increased expression of HSPB9 mRNA CTD PMID:33647349 NCBI chr10:85,641,284...85,641,929
Ensembl chr10:85,641,284...85,641,929
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO licochalcone B results in increased expression of HSPH1 mRNA CTD PMID:33647349 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Hus1b HUS1 checkpoint clamp component B increases expression ISO licochalcone B results in increased expression of HUS1B mRNA CTD PMID:33647349 NCBI chr17:33,534,113...33,534,943 JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO licochalcone B results in increased expression of ID2 mRNA CTD PMID:33647349 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ier5 immediate early response 5 increases expression ISO licochalcone B results in increased expression of IER5 mRNA CTD PMID:33647349 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Ier5l immediate early response 5-like increases expression ISO licochalcone B results in increased expression of IER5L mRNA CTD PMID:33647349 NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase increases expression ISO licochalcone B results in increased expression of IFI30 mRNA CTD PMID:33647349 NCBI chr16:18,675,651...18,679,857
Ensembl chr16:18,675,613...18,681,175
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO licochalcone B results in decreased expression of IFIH1 mRNA CTD PMID:33647349 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 increases expression ISO licochalcone B results in increased expression of IGSF11 mRNA CTD PMID:33647349 NCBI chr11:61,733,139...61,884,059
Ensembl chr11:61,733,144...61,868,348
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO licochalcone B results in decreased expression of IL1A mRNA CTD PMID:33647349 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO licochalcone B results in decreased expression of IL1B mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:25451593 PMID:33647349 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO licochalcone B results in decreased expression of IL1R1 mRNA CTD PMID:33647349 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il2rb interleukin 2 receptor subunit beta decreases expression ISO licochalcone B results in decreased expression of IL2RB mRNA CTD PMID:33647349 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
licochalcone B results in decreased expression of IL6 mRNA
CTD PMID:25451593 PMID:33647349 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inafm1 InaF-motif containing 1 increases expression ISO licochalcone B results in increased expression of INAFM1 mRNA CTD PMID:33647349 NCBI chr 1:76,976,808...76,978,292 JBrowse link
G Inhbe inhibin subunit beta E decreases expression ISO licochalcone B results in decreased expression of INHBE mRNA CTD PMID:33647349 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inka1 inka box actin regulator 1 increases expression ISO licochalcone B results in increased expression of INKA1 mRNA CTD PMID:33647349 NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953
JBrowse link
G Insm2 INSM transcriptional repressor 2 increases expression ISO licochalcone B results in increased expression of INSM2 mRNA CTD PMID:33647349 NCBI chr 6:72,973,897...72,977,777 JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO licochalcone B results in increased expression of IRF7 mRNA CTD PMID:33647349 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irgc immunity related GTPase cinema increases expression ISO licochalcone B results in increased expression of IRGC mRNA CTD PMID:33647349 NCBI chr 1:80,020,114...80,025,797
Ensembl chr 1:80,020,079...80,025,802
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO licochalcone B results in increased expression of JMJD6 mRNA CTD PMID:33647349 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jph4 junctophilin 4 increases expression ISO licochalcone B results in increased expression of JPH4 mRNA CTD PMID:33647349 NCBI chr15:28,579,579...28,588,903
Ensembl chr15:28,571,568...28,587,573
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO licochalcone B results in increased expression of JUN mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of JUN protein]
CTD PMID:25451593 PMID:33647349 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO licochalcone B results in increased expression of JUNB mRNA CTD PMID:33647349 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO licochalcone B results in increased expression of JUND mRNA CTD PMID:33647349 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 increases expression ISO licochalcone B results in increased expression of KANK3 mRNA CTD PMID:33647349 NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675
JBrowse link
G Kbtbd8 kelch repeat and BTB domain containing 8 increases expression ISO licochalcone B results in increased expression of KBTBD8 mRNA CTD PMID:33647349 NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 increases expression ISO licochalcone B results in increased expression of KCNB1 mRNA CTD PMID:33647349 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 increases expression ISO licochalcone B results in increased expression of KCNG2 mRNA CTD PMID:33647349 NCBI chr18:73,742,224...73,810,420
Ensembl chr18:73,743,074...73,808,723
JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 decreases expression ISO licochalcone B results in decreased expression of KCNH5 mRNA CTD PMID:33647349 NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 decreases expression ISO licochalcone B results in decreased expression of KCNK3 mRNA CTD PMID:33647349 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 increases expression ISO licochalcone B results in increased expression of KCNK4 mRNA CTD PMID:33647349 NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression ISO licochalcone B results in increased expression of KCTD5 mRNA CTD PMID:33647349 NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209
JBrowse link
G Kdf1 keratinocyte differentiation factor 1 increases expression ISO licochalcone B results in increased expression of KDF1 mRNA CTD PMID:33647349 NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878
JBrowse link
G Kif5a kinesin family member 5A increases expression ISO licochalcone B results in increased expression of KIF5A mRNA CTD PMID:33647349 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
JBrowse link
G Kirrel2 kirre like nephrin family adhesion molecule 2 increases expression ISO licochalcone B results in increased expression of KIRREL2 mRNA CTD PMID:33647349 NCBI chr 1:85,708,793...85,718,670
Ensembl chr 1:85,708,793...85,718,670
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO licochalcone B results in increased expression of KLF2 mRNA CTD PMID:33647349 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO licochalcone B results in increased expression of KLF4 mRNA CTD PMID:33647349 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klhl13 kelch-like family member 13 decreases expression ISO licochalcone B results in decreased expression of KLHL13 mRNA CTD PMID:33647349 NCBI chr  X:113,942,309...114,107,355
Ensembl chr  X:113,942,309...114,107,321
JBrowse link
G Klhl21 kelch-like family member 21 increases expression ISO licochalcone B results in increased expression of KLHL21 mRNA CTD PMID:33647349 NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545
JBrowse link
G Klhl25 kelch-like family member 25 increases expression ISO licochalcone B results in increased expression of KLHL25 mRNA CTD PMID:33647349 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227
JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 decreases expression ISO licochalcone B results in decreased expression of KNDC1 mRNA CTD PMID:33647349 NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362
JBrowse link
G Krt16 keratin 16 increases expression ISO licochalcone B results in increased expression of KRT16 mRNA CTD PMID:33647349 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Lag3 lymphocyte activating 3 increases expression ISO licochalcone B results in increased expression of LAG3 mRNA CTD PMID:33647349 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Ldlrad2 low density lipoprotein receptor class A domain containing 2 increases expression ISO licochalcone B results in increased expression of LDLRAD2 mRNA CTD PMID:33647349 NCBI chr 5:149,778,795...149,788,335
Ensembl chr 5:149,779,675...149,787,140
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression ISO licochalcone B results in increased expression of LDLRAD4 mRNA CTD PMID:33647349 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Leng1 leukocyte receptor cluster member 1 increases expression ISO licochalcone B results in increased expression of LENG1 mRNA CTD PMID:33647349 NCBI chr 1:65,551,983...65,556,915
Ensembl chr 1:65,551,983...65,556,915
JBrowse link
G Lgals4 galectin 4 increases expression ISO licochalcone B results in increased expression of LGALS4 mRNA CTD PMID:33647349 NCBI chr 1:84,123,497...84,132,605
Ensembl chr 1:84,124,764...84,132,481
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO licochalcone B results in increased expression of LGI4 mRNA CTD PMID:33647349 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression ISO licochalcone B results in decreased expression of LGSN mRNA CTD PMID:33647349 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression ISO licochalcone B results in increased expression of LHB mRNA CTD PMID:33647349 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lnx1 ligand of numb-protein X 1 decreases expression ISO licochalcone B results in decreased expression of LNX1 mRNA CTD PMID:33647349 NCBI chr14:33,514,429...33,617,086
Ensembl chr14:33,514,436...33,617,086
JBrowse link
G LOC102556504 titin-like decreases expression ISO licochalcone B results in decreased expression of C2ORF16 mRNA CTD PMID:33647349 NCBI chr 6:25,023,718...25,040,928 JBrowse link
G LOC290876 similar to RIKEN cDNA 1700029H14 decreases expression ISO licochalcone B results in decreased expression of C13ORF46 mRNA CTD PMID:33647349 NCBI chr16:75,974,501...75,987,629
Ensembl chr16:75,975,463...75,987,628
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO licochalcone B results in increased expression of HSPA6 mRNA CTD PMID:33647349 NCBI chr13:83,271,340...83,275,267 JBrowse link
G LOC689065 hypothetical protein LOC689065 decreases expression ISO licochalcone B results in decreased expression of C11ORF86 mRNA CTD PMID:33647349 NCBI chr 1:201,784,009...201,785,916
Ensembl chr 1:201,784,009...201,785,916
JBrowse link
G Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 decreases expression ISO licochalcone B results in decreased expression of LRFN1 mRNA CTD PMID:33647349 NCBI chr 1:83,742,442...83,761,450
Ensembl chr 1:83,682,964...83,761,449
JBrowse link
G Lrguk leucine-rich repeats and guanylate kinase domain containing decreases expression ISO licochalcone B results in decreased expression of LRGUK mRNA CTD PMID:33647349 NCBI chr 4:62,647,222...62,770,268
Ensembl chr 4:62,647,264...62,770,319
JBrowse link
G Lrrc15 leucine rich repeat containing 15 increases expression ISO licochalcone B results in increased expression of LRRC15 mRNA CTD PMID:33647349 NCBI chr11:70,469,775...70,484,268
Ensembl chr11:70,469,804...70,484,267
JBrowse link
G Lrrc43 leucine rich repeat containing 43 increases expression ISO licochalcone B results in increased expression of LRRC43 mRNA CTD PMID:33647349 NCBI chr12:33,074,149...33,092,257
Ensembl chr12:33,074,150...33,095,082
JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A increases expression ISO licochalcone B results in increased expression of LRRC8A mRNA CTD PMID:33647349 NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202
JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO licochalcone B results in decreased expression of LRRIQ3 mRNA CTD PMID:33647349 NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 increases expression ISO licochalcone B results in increased expression of LRRN4 mRNA CTD PMID:33647349 NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831
JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 increases expression ISO licochalcone B results in increased expression of LSMEM1 mRNA CTD PMID:33647349 NCBI chr 6:57,250,221...57,262,240
Ensembl chr 6:57,252,056...57,261,653
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 decreases expression ISO licochalcone B results in decreased expression of LTBP1 mRNA CTD PMID:33647349 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Ly6g6c lymphocyte antigen 6 family member G6C increases expression ISO licochalcone B results in increased expression of LY6G6C mRNA CTD PMID:33647349 NCBI chr20:3,753,632...3,757,205
Ensembl chr20:3,753,632...3,758,867
JBrowse link
G Mafa MAF bZIP transcription factor A increases expression ISO licochalcone B results in increased expression of MAFA mRNA CTD PMID:33647349 NCBI chr 7:107,432,292...107,435,061
Ensembl chr 7:107,433,605...107,434,690
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO licochalcone B results in increased expression of MAFB mRNA CTD PMID:33647349 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO licochalcone B results in increased expression of MAFF mRNA CTD PMID:33647349 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mageb3 MAGE family member B3 increases expression ISO licochalcone B results in increased expression of MAGEB3 mRNA CTD PMID:33647349 NCBI chr  X:50,865,484...50,866,479
Ensembl chr  X:50,865,484...50,866,479
JBrowse link
G Maml2 mastermind-like transcriptional coactivator 2 decreases expression ISO licochalcone B results in decreased expression of MAML2 mRNA CTD PMID:33647349 NCBI chr 8:10,268,611...10,588,307
Ensembl chr 8:10,268,665...10,587,107
JBrowse link
G Man1c1 mannosidase, alpha, class 1C, member 1 increases expression ISO licochalcone B results in increased expression of MAN1C1 mRNA CTD PMID:33647349 NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421
JBrowse link
G Mansc1 MANSC domain containing 1 decreases expression ISO licochalcone B results in decreased expression of MANSC1 mRNA CTD PMID:33647349 NCBI chr 4:167,438,817...167,459,047
Ensembl chr 4:167,439,071...167,479,606
JBrowse link
G Map1a microtubule-associated protein 1A increases expression ISO licochalcone B results in increased expression of MAP1A mRNA CTD PMID:33647349 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO licochalcone B results in increased expression of MAP2K3 mRNA CTD PMID:33647349 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 increases expression ISO licochalcone B results in increased expression of MAP3K14 mRNA CTD PMID:33647349 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map7d2 MAP7 domain containing 2 increases expression ISO licochalcone B results in increased expression of MAP7D2 mRNA CTD PMID:33647349 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:25451593 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:25451593 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25451593 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 increases expression ISO licochalcone B results in increased expression of MAPK8IP1 mRNA CTD PMID:33647349 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] CTD PMID:25451593 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Marchf1 membrane associated ring-CH-type finger 1 decreases expression ISO licochalcone B results in decreased expression of MARCHF1 mRNA CTD PMID:33647349 NCBI chr16:23,255,554...24,114,290
Ensembl chr16:23,258,799...24,114,277
JBrowse link
G Marcksl1 MARCKS-like 1 increases expression ISO licochalcone B results in increased expression of MARCKSL1 mRNA CTD PMID:33647349 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
JBrowse link
G Marcol MARCO like decreases expression ISO licochalcone B results in decreased expression of MARCOL mRNA CTD PMID:33647349 NCBI chr18:36,448,714...36,455,171 JBrowse link
G Masp1 MBL associated serine protease 1 decreases expression ISO licochalcone B results in decreased expression of MASP1 mRNA CTD PMID:33647349 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Mc5r melanocortin 5 receptor increases expression ISO licochalcone B results in increased expression of MC5R mRNA CTD PMID:33647349 NCBI chr18:61,915,188...61,920,229
Ensembl chr18:61,915,188...61,920,229
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 increases expression ISO licochalcone B results in increased expression of MCOLN1 mRNA CTD PMID:33647349 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Mdfi MyoD family inhibitor increases expression ISO licochalcone B results in increased expression of MDFI mRNA CTD PMID:33647349 NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217
JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 increases expression ISO licochalcone B results in increased expression of MDGA1 mRNA CTD PMID:33647349 NCBI chr20:7,900,327...7,963,471
Ensembl chr20:7,904,358...7,963,471
JBrowse link
G Meis1 Meis homeobox 1 decreases expression ISO licochalcone B results in decreased expression of MEIS1 mRNA CTD PMID:33647349 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO licochalcone B results in decreased expression of MEOX1 mRNA CTD PMID:33647349 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator increases expression ISO licochalcone B results in increased expression of METRNL mRNA CTD PMID:33647349 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO licochalcone B results in decreased expression of METTL7A mRNA CTD PMID:33647349 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154
JBrowse link
G Mex3a mex-3 RNA binding family member A decreases expression ISO licochalcone B results in decreased expression of MEX3A mRNA CTD PMID:33647349 NCBI chr 2:173,989,491...173,999,567
Ensembl chr 2:173,989,856...173,997,377
JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO licochalcone B results in increased expression of MEX3B mRNA CTD PMID:33647349 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
JBrowse link
G Mex3d mex-3 RNA binding family member D increases expression ISO licochalcone B results in increased expression of MEX3D mRNA CTD PMID:33647349 NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression ISO licochalcone B results in increased expression of MFGE8 mRNA CTD PMID:33647349 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein increases expression ISO licochalcone B results in increased expression of MGARP mRNA CTD PMID:33647349 NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612
JBrowse link
G Micall2 MICAL-like 2 increases expression ISO licochalcone B results in increased expression of MICALL2 mRNA CTD PMID:33647349 NCBI chr12:14,899,151...14,927,949
Ensembl chr12:14,899,157...14,927,946
JBrowse link
G Mir125b1 microRNA 125b-1 decreases expression ISO licochalcone B results in decreased expression of MIR125B1 mRNA CTD PMID:33647349 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir126b microRNA 126b decreases expression ISO licochalcone B results in decreased expression of MIR126 mRNA CTD PMID:33647349 NCBI chr 3:9,415,087...9,415,159 JBrowse link
G Mir127 microRNA 127 increases expression ISO licochalcone B results in increased expression of MIR127 mRNA CTD PMID:33647349 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311
JBrowse link
G Mir143 microRNA 143 increases expression ISO licochalcone B results in increased expression of MIR143 mRNA CTD PMID:33647349 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir146a microRNA 146a increases expression ISO licochalcone B results in increased expression of MIR146A mRNA CTD PMID:33647349 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir148a microRNA 148a decreases expression ISO licochalcone B results in decreased expression of MIR148A mRNA CTD PMID:33647349 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858
JBrowse link
G Mir181b1 microRNA 181b-1 decreases expression ISO licochalcone B results in decreased expression of MIR181B1 mRNA CTD PMID:33647349 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797
JBrowse link
G Mir191 microRNA 191 decreases expression ISO licochalcone B results in decreased expression of MIR191 mRNA CTD PMID:33647349 NCBI chr 8:109,264,098...109,264,188 JBrowse link
G Mir193a microRNA 193a increases expression ISO licochalcone B results in increased expression of MIR193A mRNA CTD PMID:33647349 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
JBrowse link
G Mir19a microRNA 19a increases expression ISO licochalcone B results in increased expression of MIR19A mRNA CTD PMID:33647349 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir200a microRNA 200a increases expression ISO licochalcone B results in increased expression of MIR200A mRNA CTD PMID:33647349 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir206 microRNA 206 increases expression ISO licochalcone B results in increased expression of MIR206 mRNA CTD PMID:33647349 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir210 microRNA 210 decreases expression ISO licoc