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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3,4-dihydroxyphenylethyleneglycol
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Accession:CHEBI:1387 term browser browse the term
Definition:A tetrol composed of ethyleneglycol having a 3,4-dihydroxyphenyl group at the 1-position.
Synonyms:exact_synonym: 4-(1,2-dihydroxyethyl)benzene-1,2-diol
 related_synonym: (3,4-dihydroxyphenyl)ethylene glycol;   1-(3,4-dihydroxyphenyl)-1,2-ethanediol;   2-hydroxy-2-(3,4-dihydroxy)phenylethanol;   3,4-Dihydroxyphenylglycol;   3,4-dihydroxyphenethyl glycol;   3,4-dihydroxyphenylethyl glycol;   DHPG;   DOPEG;   Dihydroxyphenylethylene glycol;   Formula=C8H10O4;   InChI=1S/C8H10O4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8-12H,4H2;   InChIKey=MTVWFVDWRVYDOR-UHFFFAOYSA-N;   SMILES=OCC(O)c1ccc(O)c(O)c1;   beta,3,4-trihydroxy phenethyl alcohol
 xref: CAS:3343-19-9;   HMDB:HMDB0000318;   KEGG:C05576
 xref_mesh: MESH:C010117
 xref: MetaCyc:CPD-11878;   PMID:11479664;   PMID:16218695;   PMID:16819902;   PMID:22770225;   PMID:2468969;   PMID:2645784;   PMID:2907005;   PMID:3161030;   PMID:4091997;   PMID:6146669;   PMID:6497782;   PMID:6671452;   PMID:6875564;   PMID:7176821;   Reaxys:2210995



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3,4-dihydroxyphenylethyleneglycol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3,4-dihydroxyphenylglycol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to 3,4-dihydroxyphenylglycol CTD PMID:21911610 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions
increases activity
EXP [3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein; Caffeine inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Caffeine inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein] CTD PMID:15998294 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          metabolite 19484
            3,4-dihydroxyphenylethyleneglycol 3
              (R)-3,4-dihydroxyphenylethyleneglycol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic aromatic compound 19336
                                  phenols 18605
                                    benzenediols 9146
                                      catechols 3399
                                        3,4-dihydroxyphenylethyleneglycol 3
                                          (R)-3,4-dihydroxyphenylethyleneglycol 0
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