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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:migalastat
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Accession:CHEBI:135923 term browser browse the term
Synonyms:related_synonym: 1-Deoxygalactonojirimycin;   1-Deoxygalactonojirimycin hydrochloride;   Formula=C6H13NO4;   GR181413A;   InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1;   InChIKey=LXBIFEVIBLOUGU-DPYQTVNSSA-N;   SMILES=[C@H]1([C@H]([C@H]([C@H](NC1)CO)O)O)O;   galafold;   migalastat HCl;   migalastat hydrochloride
 xref: CAS:108147-54-2;   Drug_Central:5110
 xref_mesh: MESH:C090092


show annotations for term's descendants           Sort by:
migalastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha multiple interactions ISO [GLA protein mutant form binds to GLA protein mutant form] which results in decreased susceptibility to migalastat CTD PMID:22773828 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Lct lactase decreases activity
multiple interactions		 EXP migalastat results in decreased activity of LCT protein
[migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin; [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside; [migalastat results in decreased activity of LCT protein] which results in decreased uptake of Quercetin		 CTD PMID:12663055 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      atom 19888
        nonmetal atom 19789
          nitrogen atom 18971
            nitrogen molecular entity 18971
              organonitrogen compound 18845
                organonitrogen heterocyclic compound 18167
                  piperidines 7773
                    migalastat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic heterocyclic compound 18881
                                  organic heteromonocyclic compound 17787
                                    piperidines 7773
                                      migalastat 2
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