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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chrysen-6-ol
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Accession:CHEBI:132407 term browser browse the term
Definition:A hydroxychrysene that is chrysene in which the hydrogen at position 6 has been replaced by a hydroxy group. It is a metabolite of the polycyclic aromatic hydrocarbon chrysene.
Synonyms:related_synonym: 6-chrysenol;   6-hydroxychrysene;   Formula=C18H12O;   InChI=1S/C18H12O/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11,19H;   InChIKey=VXFDOYXVHRYCGS-UHFFFAOYSA-N;   SMILES=C=1C=CC=C2C3=CC=C4C=CC=CC4=C3C=C(C21)O
 xref: CAS:37515-51-8
 xref_mesh: MESH:C087203
 xref: Reaxys:1970026


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chrysen-6-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgr progesterone receptor multiple interactions ISO 6-hydroxychrysene inhibits the reaction [Progesterone binds to PGR protein]; [Progesterone co-treated with 6-hydroxychrysene] results in decreased expression of PGR mRNA CTD PMID:9144411 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
multiple interactions		 EXP UGT1A1 protein results in increased glucuronidation of 6-hydroxychrysene
[Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 6-hydroxychrysene		 CTD PMID:1435739 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of 6-hydroxychrysene CTD PMID:7786300 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      biological role 19891
        biochemical role 19598
          metabolite 19585
            xenobiotic metabolite 16170
              chrysen-6-ol 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    main group molecular entity 19865
                      s-block molecular entity 19697
                        hydrogen molecular entity 19678
                          hydrides 19184
                            organic hydride 18719
                              organic fundamental parent 18719
                                hydrocarbon 18462
                                  cyclic hydrocarbon 17241
                                    arene 17222
                                      polycyclic arene 17047
                                        ortho-fused polycyclic arene 9845
                                          chrysene 872
                                            hydroxychrysene 3
                                              chrysen-6-ol 3
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