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Gene: Adap1 (ArfGAP with dual PH domains 1) Rattus norvegicus

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Symbol:

Adap1

Name:

ArfGAP with dual PH domains 1

RGD ID:

621418

Description:

Enables inositol 1,3,4,5 tetrakisphosphate binding activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be located in nucleus. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ADAP1 (ArfGAP with dual PH domains 1); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

arf-GAP with dual PH domain-containing protein 1; Centa1; centaurin, alpha 1; p42IP4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADAP1 (ArfGAP with dual PH domains 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Adap1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adap1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADAP1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADAP1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adap1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADAP1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADAP1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adap1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Adap1 (ArfGAP with dual PH domains 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ADAP2 (ArfGAP with dual PH domains 2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ADAP1 (ArfGAP with dual PH domains 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Adap1 (ArfGAP with dual PH domains 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:92360	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adap1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adap1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	20,438,091 - 20,489,961 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	20,438,063 - 20,495,020 (+)	Ensembl				GRCr8
mRatBN7.2	12	15,323,913 - 15,376,110 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	15,324,209 - 15,380,831 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	16,134,353 - 16,186,232 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,758,093 - 16,809,976 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,784,243 - 15,836,094 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	17,416,327 - 17,468,212 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	17,416,327 - 17,468,212 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	19,402,559 - 19,454,794 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	15,825,017 - 15,877,643 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	17,078,350 - 17,130,259 (+)	NCBI		Celera
RGSC_v3.1	12	15,855,021 - 15,906,562 (+)	NCBI
Cytogenetic Map	12	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

inflammatory bowel disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

acetamide (EXP)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

Bufotalin (ISO)

butan-1-ol (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

elemental selenium (ISO)

ethanol (ISO)

ethylparaben (ISO)

flavonoids (EXP)

folic acid (ISO)

fulvestrant (ISO)

lead(0) (ISO)

leflunomide (ISO)

Licochalcone B (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

toluene (ISO)

tributylstannane (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO)

nucleus (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

Molecular Function

anion binding (IEA)

GTPase activator activity (IBA,IEA,ISO)

inositol 1,3,4,5 tetrakisphosphate binding (IDA)

metal ion binding (IEA)

phosphatidylinositol bisphosphate binding (IEA)

phosphatidylinositol-3,4,5-trisphosphate binding (IBA,IDA)

protein binding (ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Expression of the brain-specific membrane adapter protein p42IP4/centaurin alpha, a Ins(1,3,4,5)P4/PtdIns(3,4,5)P3 binding protein, in developing rat brain.	Aggensteiner M and Reiser G, Brain Res Dev Brain Res 2003 Apr 14;142(1):77-87.
2.	Identification of rat brain p42(IP4), a high-affinity inositol(1,3,4, 5)tetrakisphosphate/phosphatidylinositol(3,4,5)trisphosphate binding protein.	Aggensteiner M, etal., Biochim Biophys Acta 1998 Sep 8;1387(1-2):117-28.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain.	Hammonds-Odie LP, etal., J Biol Chem 1996 Aug 2;271(31):18859-68.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Oligomerization controls in tissue-specific manner ligand binding of native, affinity-purified p42(IP4)/centaurin alpha1 and cytohesins-proteins with high affinity for the messengers D-inositol 1,3,4,5-tetrakisphosphate/phosphatidylinositol 3,4,5-trisphosphate.	Stricker R, etal., Biochim Biophys Acta 2003 Sep 23;1651(1-2):102-15.

Additional References at PubMed

PMID:10333475	PMID:10448098	PMID:12477932	PMID:15082226	PMID:15679100	PMID:15923660	PMID:16805830	PMID:17635995	PMID:18298663	PMID:23516302	PMID:30206251

Genomics

Comparative Map Data

Adap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	20,438,091 - 20,489,961 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	20,438,063 - 20,495,020 (+)	Ensembl				GRCr8
mRatBN7.2	12	15,323,913 - 15,376,110 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	15,324,209 - 15,380,831 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	16,134,353 - 16,186,232 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,758,093 - 16,809,976 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,784,243 - 15,836,094 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	17,416,327 - 17,468,212 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	17,416,327 - 17,468,212 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	19,402,559 - 19,454,794 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	15,825,017 - 15,877,643 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	17,078,350 - 17,130,259 (+)	NCBI		Celera
RGSC_v3.1	12	15,855,021 - 15,906,562 (+)	NCBI
Cytogenetic Map	12	q11	NCBI

ADAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	897,900 - 955,407 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	897,900 - 955,407 (-)	Ensembl			hg38	GRCh38
GRCh37	7	937,537 - 995,043 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	904,066 - 960,811 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	710,780 - 767,508	NCBI
Celera	7	906,136 - 962,035 (-)	NCBI		Celera
Cytogenetic Map	7	p22.3	NCBI
HuRef	7	855,527 - 893,573 (-)	NCBI		HuRef
CHM1_1	7	936,645 - 993,431 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	1,001,683 - 1,060,405 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	992,062 - 1,048,924 (-)	NCBI

Adap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	139,257,631 - 139,311,516 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	139,257,631 - 139,311,377 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	139,271,876 - 139,325,763 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	139,271,876 - 139,325,622 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	139,747,830 - 139,801,418 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	139,525,518 - 139,559,961 (-)	NCBI		MGSCv36	mm8
Celera	5	136,325,945 - 136,379,615 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	78.27	NCBI

Adap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	8,635,463 - 8,674,455 (-)	Ensembl
ChiLan1.0	NW_004955460	8,635,463 - 8,674,455 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	5,841,176 - 5,899,642 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	54,165,865 - 54,224,306 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	1,054,499 - 1,112,240 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	1,269,235 - 1,316,351 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	1,269,235 - 1,326,102 (-)	Ensembl			panPan2	panpan1.1

ADAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	15,921,865 - 15,976,101 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	15,898,326 - 15,973,771 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	17,394,927 - 17,448,262 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	16,052,553 - 16,105,914 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	16,028,493 - 16,105,914 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	15,855,375 - 15,908,735 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	15,781,938 - 15,835,092 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	16,070,134 - 16,124,464 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Adap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	143,855,837 - 143,879,769 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936754	1,131,500 - 1,154,528 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936754	1,130,585 - 1,154,459 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	547,364 - 615,471 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	548,823 - 615,471 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	429,376 - 430,952 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	3	695,020 - 722,372 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	20,617,948 - 20,677,848 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	20,617,995 - 20,680,628 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666090	1,013,133 - 1,073,527 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	26,481,054 - 26,518,469 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624740	26,481,036 - 26,518,315 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Adap1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	13,876,887 - 13,930,297 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Adap1
890 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	415
Count of miRNA genes:	196
Interacting mature miRNAs:	236
Transcripts:	ENSRNOT00000001736
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
61443	Btemp2	Thermal response to stress QTL 2	3.3	0.000094	body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	12	20139028	26430640	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	12233000	30490641	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	18749469	36488809	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	18749469	34312613	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	33700556	Rat

Markers in Region

RH131687

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	15,375,796 - 15,376,007 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	17,467,900 - 17,468,110	NCBI	Rnor6.0
Rnor_5.0	12	19,454,482 - 19,454,692	UniSTS	Rnor5.0
RGSC_v3.4	12	15,877,331 - 15,877,541	UniSTS	RGSC3.4
Celera	12	17,129,947 - 17,130,157	UniSTS
RH 3.4 Map	12	245.9	UniSTS
Cytogenetic Map	12	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF123047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ007422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ007616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC099775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U51013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000089590 ⟹ ENSRNOP00000075236

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	20,438,160 - 20,491,031 (+)	Ensembl
mRatBN7.2 Ensembl	12	15,324,237 - 15,376,109 (+)	Ensembl
Rnor_6.0 Ensembl	12	17,416,327 - 17,468,212 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092186 ⟹ ENSRNOP00000074351

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	20,438,063 - 20,495,020 (+)	Ensembl
mRatBN7.2 Ensembl	12	15,324,209 - 15,380,831 (+)	Ensembl
Rnor_6.0 Ensembl	12	17,416,411 - 17,467,184 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100857 ⟹ ENSRNOP00000080905

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	20,439,040 - 20,491,031 (+)	Ensembl
mRatBN7.2 Ensembl	12	15,325,407 - 15,376,109 (+)	Ensembl

RefSeq Acc Id:

NM_133567 ⟹ NP_598251

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	20,438,091 - 20,489,961 (+)	NCBI
mRatBN7.2	12	15,324,237 - 15,376,109 (+)	NCBI
Rnor_6.0	12	17,416,327 - 17,468,212 (+)	NCBI
Rnor_5.0	12	19,402,559 - 19,454,794 (+)	NCBI
RGSC_v3.4	12	15,825,017 - 15,877,643 (+)	RGD
Celera	12	17,078,350 - 17,130,259 (+)	RGD

Sequence:

show sequence

CGATGGCGCAAGGCGGACGGCGGGCGCGCGGCGCGGGGCCCTAGCTGGGCGGGCGTGCTCGGGA
CGGCGCGGTGGCCGCGCAGCCATGGCCGGGGAGCGGCGCCGGGCGCTGCTGGAGCTGCTGACGC
GTCCGGGGAACTCGCGCTGCGCTGACTGCGGAGCCCCGGATCCTGACTGGGCGTCCTACACCCT
GGGTGTGTTCATCTGTTTGAGCTGCTCTGGGATCCACCGGAACATCCCCCAGGTCAGCAAGGTG
AAGTCAGTTCGTCTGGATGCCTGGGATGAGACCCAAGTTGAGTTCATGACATCTCATGGGAACG
AGGCTGCCAGAGCCACATTTGAGTCCAAAGTACCACCCTTCTACTACCGGCCCACGTTCTCCGA
CTGCCAACTCCTACGTGAGCAGTGGATCCGTGCCAAGTATGAGAGGCAAGAATTCCTTCATGTG
GAGAAACAGGAACCGTACTCTACAGGATACCGTGAGGGCCTTCTCTGGAAGCGTGGCCGGGACA
ACGGACAGTTCTTAAGTCGGAAGTTTGTGCTGACAGAACGAGAGGGTGCTCTGAAATACTTCAA
CAAAAATGACGCTAAGGAGCCTAAGGCTGTCATGAAGATTGAGCACCTGAATGCCACCTTCCAG
CCAGCCAAGATCGGCCACCCCCATGGCCTGCAGGTCACCTACTTGAAGGACAACAGCACTCGCA
ACATCTTTATCTACCACGAGGATGGCAAGGAGATCGTGGACTGGTTCAATGCGCTGCGAGCAGC
CCGCTTCCACTACCTGCAGGTGGCTTTCCCAGGAGCCAGTGACGCAGATCTGGTGCCCAAGCTC
TCTAGGAACTACCTGAAGGAAGGCTACATGGAGAAGACAGGGCCCAAGCAGACAGAAGGCTTTC
GGAAGCGCTGGTTCACCATGGACGACCGGAGGCTCATGTACTTCAAAGACCCTCTGGATGCCTT
TGCCCGAGGGGAAGTCTTCATTGGCAGCAAGGAAAGTGGTTACACGGTCCTGGAGGGCCTCCCA
CCGTCAACCCAGAGTCACCACTGGCCCCATGGCATCACCATTGTCACCCCTGACCGAAAATTCC
TGTTCACGTGTGAGACAGAGTCAGACCAGAGGGAGTGGATAGCAGCCTTCCAGAAGGTGGTGGA
CAGGCCCATGCTGCCTCAGGAGTACGCAGTGGAAGCCCACTTCAAGCATAAACCCTAAGGAAGA
GAGCCCGGAGGCCCCAGGATTCTGCACTCGTGTGGCGGCGCTGGACAGCAGGAGAGCCTCTGTT
CCTCGGTGTGGCCCAGGCATGGCCAGGTGGGGCTCAGGCAAGCCCATCAGATAGACAGTTTTTC
AGAACCTCATTAAAGTTGAAGGCAGACTTGGTTCTGGGCCTCACTTGACCCTGGCCCTGTCATG
ACGCTCCCAGCCACGCCCAGCCGACCCACCCATTTTCCTGCTGCTGGAGGAAGCCCTGCCTCCC
AACTTGAGCAGGACCCTACTAACTCTTCTGGCCTGAGGGGATCTTGGCCTCAGGACAGGACTTG
GTGCTGGGCTGCTGTGGACAGCCATGGACAGCCATGAACAGCTGTGGCAGCGGGCTGGCCTGGC
TGCTGGGGACTCACTCTGGGATGTGCCGCATGCCTCCCCACTCCTCTCCCCACTTCAACAAGTA
TTTATTGAGCACCTGCTGTGTGTCAGTCAGGGATCAAGGGTCAGGGGTCAGCTCTCCTTCCCCT
AGGGCTGACCCAGCTGGAGCATTGGGGGTCAGGTATTTTTCCAAGAGAACTGTGTGCATAGGCC
CTGCACCCACCTGTTTGCCCCACCCCCCCACCCCCAGGCCCCTTGGGACAGCTGGCTGGAGCAA
CCAGGAGGGAGCCTAGCCTGCAGGGTGCTGTGCATGGAGCCCAGGAGCGGTTTCCTTGGGAGCC
AGGGAGCGCCCCATCCCATCTGCTTTTGGGCGTCAGTGCCCAGCTCGGTGCTGTCCCCGCTTTG
TAACCCATGCCCTCTGGCCCTGCCCTTACAGTCTTTGAGCCCTTGATGAATGAAAGCCCAAGCC
AAGAAGTGGTCATTGGCAGGAATGGCTGCCCCCCAGCCCTGATTGCTGCTGGCAGGCCAGTAGT
TAAAGCTACCTGTATTTATTTCCCCCACTGCCCTCTGGCCACCCCAACAGATGGGCTCCCTTCT
ATGGGATCCCCAAAGGGCAGGTCCTGGCCGCTGGACAGCTGGGGAGCATTGATGGGGGACCCAT
CTGTGAATGACCTGGTCCCTCCTCAAAGCTAAGCCCTAGGGACCTGGGGGGAGGGGTCCTTAGT
TGGGCTTCTGCTGCCCTGTGTCATGTCGCCTGGAATAAAGTGTGGCTCTGGCGTTGTCAAAAAA
AAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017598251 ⟹ XP_017453740

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	20,439,264 - 20,489,961 (+)	NCBI
mRatBN7.2	12	15,325,596 - 15,376,110 (+)	NCBI
Rnor_6.0	12	17,417,466 - 17,468,212 (+)	NCBI

Sequence:

show sequence

GTAAGTGCATGCCACCCCAGGGGCCCTGGTGTCCCTGGGAGGAGACATTGACCAAGCTTCAGTG
GGAAGCTGGGCAAGATGAAGTAGTCCTTTCCTGGTCTCCAGAGGCCCTGCAGGGCCCTGCCATG
GTGCAGTGGGGTGGTGGCTCCCTGGTTCTGCATGGTTCCCACCTCCCTCTCTCAGACCTGCCTT
TCAACATGTTTGGGAAAGCCGGCTATGCCAGAGTCTCTGGAGTCCCTGATCCTGACTGGGCGTC
CTACACCCTGGGTGTGTTCATCTGTTTGAGCTGCTCTGGGATCCACCGGAACATCCCCCAGGTC
AGCAAGGTGAAGTCAGTTCGTCTGGATGCCTGGGATGAGACCCAAGTTGAGTTCATGACATCTC
ATGGGAACGAGGCTGCCAGAGCCACATTTGAGTCCAAAGTACCACCCTTCTACTACCGGCCCAC
GTTCTCCGACTGCCAACTCCTACGTGAGCAGTGGATCCGTGCCAAGTATGAGAGGCAAGAATTC
CTTCATGTGGAGAAACAGGAACCGTACTCTACAGGATACCGTGAGGGCCTTCTCTGGAAGCGTG
GCCGGGACAACGGACAGTTCTTAAGTCGGAAGTTTGTGCTGACAGAACGAGAGGGTGCTCTGAA
ATACTTCAACAAAAATGACGCTAAGGAGCCTAAGGCTGTCATGAAGATTGAGCACCTGAATGCC
ACCTTCCAGCCAGCCAAGATCGGCCACCCCCATGGCCTGCAGGTCACCTACTTGAAGGACAACA
GCACTCGCAACATCTTTATCTACCATGAGGATGGCAAGGAGATCGTGGACTGGTTCAATGCGCT
GCGAGCAGCCCGCTTCCACTACCTGCAGGTGGCTTTCCCAGGAGCCAGTGACGCAGATCTGGTG
CCCAAGCTCTCTAGGAACTACCTGAAGGAAGGCTACATGGAGAAGACAGGGCCCAAGCAGACAG
AAGGCTTTCGGAAGCGCTGGTTCACCATGGACGACCGGAGGCTCATGTACTTCAAAGACCCTCT
GGATGCCTTTGCCCGAGGGGAAGTCTTCATTGGCAGCAAGGAAAGTGGTTACACGGTCCTGGAG
GGCCTCCCACCGTCAACCCAGAGTCACCACTGGCCCCATGGCATCACCATTGTCACCCCTGACC
GAAAATTCCTGTTCACGTGTGAGACAGAGTCAGACCAGAGGGAGTGGATAGCAGCCTTCCAGAA
GGTGGTGGACAGGCCCATGCTGCCTCAGGAGTACGCAGTGGAAGCCCACTTCAAGCATAAACCC
TAAGGAAGAGAGCCCGGAGGCCCCAGGATTCTGCACTCGTGTGGCGGCGCTGGACAGCAGGAGA
GCCTCTGTTCCTCGGTGTGGCCCAGGCATGGCCAGGTGGGGCTCAGGCAAGCCCATCAGATAGA
CAGTTTTTCAGAACCTCATTAAAGTTGAAGGCAGACTTGGTTCTGGGCCTCACTTGACCCTGGC
CCTGTCATGACGCTCCCAGCCACGCCCAGCCGACCCACCCATTTTCCTGCTGCTGGAGGAAGCC
CTGCCTCCCAACTTGAGCAGGACCCTACTAACTCTTCTGGCCTGAGGGGATCTTGGCCTCAGGA
CAGGACTTGGTGCTGGGCTGCTGTGGACAGCCATGGACAGCCATGAACAGCTGTGGCAGCGGGC
TGGCCTGGCTGCTGGGGACTCACTCTGGGATGTGCCGCATGCCTCCCCACTCCTCTCCCCACTT
CAACAAGTATTTATTGAGCACCTGCTGTGTGTCAGTCAGGGATCAAGGGTCAGGGGTCAGCTCT
CCTTCCCCTAGGGCTGACCCAGCTGGAGCATTGGGGGTCAGGTATTTTTCCAAGAGAACTGTGT
GCATAGGCCCTGCACCCACCTGTTTGCCCCACCCCCCCACCCCCAGGCCCCTTGGGACAGCTGG
CTGGAGCAACCAGGAGGGAGCCTAGCCTGCAGGGTGCTGTGCATGGAGCCCAGGAGCGGTTTCC
TTGGGAGCCAGGGAGCGCCCCATCCCATCTGCTTTTGGGCGTCAGTGCCCAGCTCGGTGCTGTC
CCCGCTTTGTAACCCATGCCCTCTGGCCCTGCCCTTACAGTCTTTGAGCCCTTGATGAATGAAA
GCCCAAGCCAAGAAGTGGTCATTGGCAGGAATGGCTGCCCCCCAGCCCTGATTGCTGCTGGCAG
GCCAGTAGTTAAAGCTACCTGTATTTATTTCCCCCACTGCCCTCTGGCCACCCCAACAGATGGG
CTCCCTTCTATGGGATCCCCAAAGGGCAGGTCCTGGCCGCTGGACAGCTGGGGAGCATTGATGG
GGGACCCATCTGTGAATGACCTGGTCCCTCCTCAAAGCTAAGCCCTAGGGACCTGGGGGGAGGG
GTCCTTAGTTGGGCTTCTGCTGCCCTGTGTCATGTCGCCTGGAATAAAGTGTGGCTCTGGCGTT
GTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_598251	(Get FASTA)	NCBI Sequence Viewer
	XP_017453740	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52683	(Get FASTA)	NCBI Sequence Viewer
	AAD28040	(Get FASTA)	NCBI Sequence Viewer
	AAH99775	(Get FASTA)	NCBI Sequence Viewer
	CAA07496	(Get FASTA)	NCBI Sequence Viewer
	CAA07581	(Get FASTA)	NCBI Sequence Viewer
	EDL89776	(Get FASTA)	NCBI Sequence Viewer
	EDL89777	(Get FASTA)	NCBI Sequence Viewer
	EDL89778	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074351.2
	ENSRNOP00000075236
	ENSRNOP00000075236.1
	ENSRNOP00000080905
	ENSRNOP00000080905.2

RefSeq Acc Id:

NP_598251 ⟸ NM_133567

- UniProtKB:

O88768 (UniProtKB/TrEMBL), Q9QUI9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGERRRALLELLTRPGNSRCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDA
WDETQVEFMTSHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFLHVEKQEPYS
TGYREGLLWKRGRDNGQFLSRKFVLTEREGALKYFNKNDAKEPKAVMKIEHLNATFQPAKIGHP
HGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKE
GYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLEGLPPSTQSHH
WPHGITIVTPDRKFLFTCETESDQREWIAAFQKVVDRPMLPQEYAVEAHFKHKP

hide sequence

RefSeq Acc Id:	XP_017453740 ⟸ XM_017598251
- Peptide Label:	isoform X1
- UniProtKB:	Q9QUI9 (UniProtKB/TrEMBL), A0A8I5ZRW6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPPQGPWCPWEETLTKLQWEAGQDEVVLSWSPEALQGPAMVQWGGGSLVLHGSHLPLSDLPFNM FGKAGYARVSGVPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWDETQVEFMTSHGN EAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFLHVEKQEPYSTGYREGLLWKRGRD NGQFLSRKFVLTEREGALKYFNKNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTR NIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGF RKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLEGLPPSTQSHHWPHGITIVTPDRKF LFTCETESDQREWIAAFQKVVDRPMLPQEYAVEAHFKHKP hide sequence

Ensembl Acc Id:

ENSRNOP00000074351 ⟸ ENSRNOT00000092186

Ensembl Acc Id:

ENSRNOP00000075236 ⟸ ENSRNOT00000089590

Ensembl Acc Id:

ENSRNOP00000080905 ⟸ ENSRNOT00000100857

Protein Domains

Arf-GAP PH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K7U5-F1-model_v2	AlphaFold	A0A0G2K7U5	1-414	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698469

Promoter ID:

EPDNEW_R8993

Type:

initiation region

Name:

Adap1_1

Description:

ArfGAP with dual PH domains 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	17,416,234 - 17,416,294	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621418	AgrOrtholog
BioCyc Gene	G2FUF-19887	BioCyc
Ensembl Genes	ENSRNOG00000054033	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000089590	ENTREZGENE
	ENSRNOT00000089590.3	UniProtKB/TrEMBL
	ENSRNOT00000092186.3	UniProtKB/TrEMBL
	ENSRNOT00000100857	ENTREZGENE
	ENSRNOT00000100857.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.220.150	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7933317	IMAGE-MGC_LOAD
InterPro	Arf-GAP_dual-PH_domain	UniProtKB/TrEMBL
	ArfGAP	UniProtKB/TrEMBL
	ARFGAP/RecO	UniProtKB/TrEMBL
	ArfGAP_dom_sf	UniProtKB/TrEMBL
	PH1_ADAP	UniProtKB/TrEMBL
	PH2_ADAP	UniProtKB/TrEMBL
	PH_type	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
KEGG Report	rno:171097	UniProtKB/TrEMBL
MGC_CLONE	MGC:124568	IMAGE-MGC_LOAD
NCBI Gene	171097	ENTREZGENE
PANTHER	ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN	UniProtKB/TrEMBL
Pfam	ArfGap	UniProtKB/TrEMBL
	PF00169	UniProtKB/TrEMBL
PhenoGen	Adap1	PhenoGen
PRINTS	REVINTRACTNG	UniProtKB/TrEMBL
PROSITE	ARFGAP	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000054033	RatGTEx
SMART	ArfGap	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF57863	UniProtKB/TrEMBL
UniProt	A0A0G2K7U5_RAT	UniProtKB/TrEMBL
	A0A8I5ZRW6	ENTREZGENE, UniProtKB/TrEMBL
	A6K1X0_RAT	UniProtKB/TrEMBL
	O88768	ENTREZGENE, UniProtKB/TrEMBL
	Q9QUI9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-15	Adap1	ArfGAP with dual PH domains 1	Centa1	centaurin, alpha 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Centa1	centaurin, alpha 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Centa1	centaurin, alpha 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed with various levels in the cortex, hippocampus, thalamus, striatum and Cerebellum	632412
gene_process	may link the activation of phosphoinositide 3-kinase to downstream responses in the brain	632413

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)