ADAP1 (ArfGAP with dual PH domains 1) - Rat Genome Database

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Gene: ADAP1 (ArfGAP with dual PH domains 1) Pan paniscus
Analyze
Symbol: ADAP1
Name: ArfGAP with dual PH domains 1
RGD ID: 11851537
Description: ENCODES a protein that exhibits inositol 1,3,4,5 tetrakisphosphate binding (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH genetic disease (ortholog); inflammatory bowel disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: arf-GAP with dual PH domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v265,841,176 - 5,899,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1754,165,865 - 54,224,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v071,054,499 - 1,112,240 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.171,269,235 - 1,316,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl71,269,235 - 1,326,102 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v265,841,176 - 5,899,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1754,165,865 - 54,224,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v071,054,499 - 1,112,240 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.171,269,235 - 1,316,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl71,269,235 - 1,326,102 (-)Ensemblpanpan1.1panPan2
ADAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387897,900 - 955,407 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7897,900 - 955,407 (-)EnsemblGRCh38hg38GRCh38
GRCh377937,537 - 995,043 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367904,066 - 960,811 (-)NCBINCBI36Build 36hg18NCBI36
Build 347710,780 - 767,508NCBI
Celera7906,136 - 962,035 (-)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef7855,527 - 893,573 (-)NCBIHuRef
CHM1_17936,645 - 993,431 (-)NCBICHM1_1
T2T-CHM13v2.071,001,683 - 1,060,405 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27992,062 - 1,048,924 (-)NCBI
Adap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395139,257,631 - 139,311,516 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5139,257,631 - 139,311,377 (-)EnsemblGRCm39 Ensembl
GRCm385139,271,876 - 139,325,763 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5139,271,876 - 139,325,622 (-)EnsemblGRCm38mm10GRCm38
MGSCv375139,747,830 - 139,801,418 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365139,525,518 - 139,559,961 (-)NCBIMGSCv36mm8
Celera5136,325,945 - 136,379,615 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map578.27NCBI
Adap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81220,438,091 - 20,489,961 (+)NCBIGRCr8
mRatBN7.21215,323,913 - 15,376,110 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1215,324,209 - 15,380,831 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1216,134,353 - 16,186,232 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,758,093 - 16,809,976 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,784,243 - 15,836,094 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01217,416,327 - 17,468,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,416,327 - 17,468,212 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01219,402,559 - 19,454,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41215,825,017 - 15,877,643 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11215,855,021 - 15,906,562 (+)NCBI
Celera1217,078,350 - 17,130,259 (+)NCBICelera
Cytogenetic Map12q11NCBI
Adap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554608,635,463 - 8,674,455 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554608,635,463 - 8,674,455 (-)NCBIChiLan1.0ChiLan1.0
ADAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1615,921,865 - 15,976,101 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl615,898,326 - 15,973,771 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha617,394,927 - 17,448,262 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0616,052,553 - 16,105,914 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl616,028,493 - 16,105,914 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1615,855,375 - 15,908,735 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0615,781,938 - 15,835,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0616,070,134 - 16,124,464 (+)NCBIUU_Cfam_GSD_1.0
Adap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344143,855,837 - 143,879,769 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367541,131,500 - 1,154,528 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367541,130,585 - 1,154,459 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3547,364 - 615,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13548,823 - 615,471 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23429,376 - 430,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.23695,020 - 722,372 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12820,617,948 - 20,677,848 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2820,617,995 - 20,680,628 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660901,013,133 - 1,073,527 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474026,481,054 - 26,518,469 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474026,481,036 - 26,518,315 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000043947   ⟹   ENSPPAP00000021147
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl71,269,235 - 1,316,351 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043949   ⟹   ENSPPAP00000021149
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl71,270,171 - 1,292,845 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043955   ⟹   ENSPPAP00000021155
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl71,270,256 - 1,326,102 (-)Ensembl
RefSeq Acc Id: XM_034963473   ⟹   XP_034819364
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v265,841,176 - 5,899,642 (-)NCBI
NHGRI_mPanPan1754,165,865 - 54,224,306 (-)NCBI
Mhudiblu_PPA_v071,054,499 - 1,112,240 (-)NCBI
RefSeq Acc Id: XM_034963474   ⟹   XP_034819365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v265,841,176 - 5,899,642 (-)NCBI
NHGRI_mPanPan1754,165,865 - 54,224,056 (-)NCBI
Mhudiblu_PPA_v071,054,499 - 1,112,003 (-)NCBI
RefSeq Acc Id: XM_057302815   ⟹   XP_057158798
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v265,841,176 - 5,882,518 (-)NCBI
NHGRI_mPanPan1754,165,865 - 54,207,207 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034819364 (Get FASTA)   NCBI Sequence Viewer  
  XP_034819365 (Get FASTA)   NCBI Sequence Viewer  
  XP_057158798 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021147.1
  ENSPPAP00000021149.1
  ENSPPAP00000021155.1
Reference Protein Sequences
RefSeq Acc Id: XP_034819364   ⟸   XM_034963473
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AV20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819365   ⟸   XM_034963474
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AV20 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000021149   ⟸   ENSPPAT00000043949
RefSeq Acc Id: ENSPPAP00000021147   ⟸   ENSPPAT00000043947
RefSeq Acc Id: ENSPPAP00000021155   ⟸   ENSPPAT00000043955
RefSeq Acc Id: XP_057158798   ⟸   XM_057302815
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AV20 (UniProtKB/TrEMBL)
Protein Domains
Arf-GAP   PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033795 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043947.1 UniProtKB/TrEMBL
  ENSPPAT00000043949.1 UniProtKB/TrEMBL
  ENSPPAT00000043955.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH1_ADAP UniProtKB/TrEMBL
  PH2_ADAP UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene ADAP1 ENTREZGENE
PANTHER ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART ArfGap UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A2R9AV20 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZ80_PANPA UniProtKB/TrEMBL
  A0A2R9B169_PANPA UniProtKB/TrEMBL