Muc5ac (mucin 5AC, oligomeric mucus/gel-forming) - Rat Genome Database

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Gene: Muc5ac (mucin 5AC, oligomeric mucus/gel-forming) Rattus norvegicus
Analyze
Symbol: Muc5ac
Name: mucin 5AC, oligomeric mucus/gel-forming
RGD ID: 62001
Description: Predicted to be an extracellular matrix structural constituent. Involved in several processes, including cellular response to epidermal growth factor stimulus; cellular response to retinoic acid; and response to ozone. Located in extracellular space. Used to study chronic obstructive pulmonary disease; dry eye syndrome; gastric ulcer; and stomach disease. Biomarker of asthma; gastric ulcer; otitis media; pulmonary fibrosis; and rhinitis (multiple). Human ortholog(s) of this gene implicated in dry eye syndrome. Orthologous to human MUC5AC (mucin 5AC, oligomeric mucus/gel-forming); INTERACTS WITH (E)-roxithromycin; (R,R,R)-alpha-tocopherol; 1,8-cineole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07006032.1; LOC682837; mucin 5, subtypes A and C; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin-5AC; similar to mucin 5, subtype B, tracheobronchial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,293,717 - 206,326,006 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1206,293,869 - 206,326,006 (+)EnsemblGRCr8
mRatBN7.21196,864,336 - 196,896,475 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,864,336 - 196,896,475 (+)EnsemblmRatBN7.2
Rnor_6.01214,725,482 - 214,756,653 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,727,416 - 214,741,252 (+)NCBIrn6Rnor6.0
Rnor_5.01221,642,507 - 221,671,770 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1194,493,496 - 194,524,940 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(E)-roxithromycin  (EXP)
(R,R,R)-alpha-tocopherol  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-naphthoquinone  (ISO)
1,8-cineole  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6alpha-methylprednisolone  (EXP)
8'-apo-beta,psi-caroten-8'-al  (ISO)
9-cis-retinoic acid  (ISO)
A-967079  (ISO)
acrolein  (EXP,ISO)
afatinib  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
alizarin  (ISO)
all-trans-4-hydroxyretinoic acid  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
aluminium hydroxide  (ISO)
amitrole  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
astragaloside IV  (EXP)
Atractylodin  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-carotene  (ISO)
bisphenol A  (ISO)
bleomycin A2  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbon nanotube  (ISO)
ceric oxide  (ISO)
CHIR 99021  (ISO)
chlorphenamine  (ISO)
chromium(6+)  (ISO)
citric acid  (ISO)
coniferyl aldehyde  (ISO)
curcumin  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dihydroxyacetone  (ISO)
dimethyl sulfoxide  (ISO)
dioscin  (ISO)
dioxygen  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
erlotinib hydrochloride  (ISO)
ethyl methanesulfonate  (ISO)
euxanthone  (ISO)
Fidarestat  (ISO)
flavonoids  (EXP)
fluoranthene  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
gamma-tocopherol  (EXP)
gefitinib  (ISO)
glucose  (ISO)
glycerol  (EXP)
glycyrrhizinic acid  (ISO)
histamine  (ISO)
hydrogen peroxide  (ISO)
icariin  (EXP)
kaempferol  (ISO)
lead diacetate  (ISO)
leukotriene B4  (EXP)
leukotriene C4  (EXP)
leukotriene D4  (EXP)
leukotriene E4  (EXP)
lipopolysaccharide  (EXP,ISO)
lixisenatide  (ISO)
LY294002  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
mevalonic acid  (ISO)
MitoTEMPO  (ISO)
MK 571  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
naringin  (ISO)
nickel atom  (ISO)
Niflumic acid  (ISO)
Nivalenol  (ISO)
nobiletin  (EXP)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
Paeonol  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
platycodin D  (ISO)
platycodin D3  (ISO)
potassium dichromate  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 203580  (ISO)
scopolamine  (EXP,ISO)
selenium atom  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
StemRegenin 1  (ISO)
sulforaphane  (ISO)
tebuconazole  (ISO)
theaflavin  (EXP)
Theaflavin 3,3'-digallate  (EXP)
tobramycin  (ISO)
triamcinolone acetonide  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tyrphostin AG 1478  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
zearalenone  (ISO)
zileuton  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Gastric mucin phenotype defines tumour progression and prognosis of intrahepatic cholangiocarcinoma: gastric foveolar type is associated with aggressive tumour behaviour. Aishima S, etal., Histopathology. 2006 Jul;49(1):35-44.
2. Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines. Balague C, etal., Gastroenterology. 1994 Apr;106(4):1054-61.
3. In situ hybridization shows distinct patterns of mucin gene expression in normal, benign, and malignant pancreas tissues. Balague C, etal., Gastroenterology. 1995 Sep;109(3):953-64.
4. Prognostic value of serum MUC5AC mucin in patients with cholangiocarcinoma. Boonla C, etal., Cancer. 2003 Oct 1;98(7):1438-43.
5. MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma. Boonla C, etal., World J Gastroenterol. 2005 Aug 28;11(32):4939-46.
6. Effect of Myrtol standardized on mucus hypersecretion and clearance of Pseudomonas aeruginosa in a rat model of chronic obstructive pulmonary disease. Cao L, etal., Arzneimittelforschung. 2011;61(12):685-92. doi: 10.1055/s-0031-1300588.
7. Mucinous nonneoplastic cyst of the pancreas: apomucin phenotype distinguishes this entity from intraductal papillary mucinous neoplasm. Cao W, etal., Hum Pathol. 2010 Apr;41(4):513-21. Epub 2009 Dec 1.
8. MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients. Caramori G, etal., Histopathology. 2009 Sep;55(3):321-31.
9. Phenotypic alterations of mucins and cytokeratins during gallbladder carcinogenesis. Chang HJ, etal., Pathol Int. 2004 Aug;54(8):576-84.
10. Toll-like receptor 4 relates to lipopolysaccharide-induced mucus hypersecretion in rat airway. Chen L, etal., Arch Med Res. 2009 Jan;40(1):10-7.
11. Inflammatory and epithelial responses during the development of ozone-induced mucous cell metaplasia in the nasal epithelium of rats. Cho HY, etal., Toxicol Sci. 1999 Sep;51(1):135-45.
12. In vivo characterization of the molecular-genetic changes in gastric mucosa during the development of acute gastritis and stress ulceration. Choo D, etal., J Trauma. 2002 Apr;52(4):720-5; discussion 725-6.
13. Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury. Cortijo J, etal., Br J Pharmacol. 2009 Feb;156(3):534-44.
14. Alterations of the ocular surface epithelial MUC16 and goblet cell MUC5AC in patients with atopic keratoconjunctivitis. Dogru M, etal., Allergy. 2008 Oct;63(10):1324-34. doi: 10.1111/j.1398-9995.2008.01781.x.
15. Ocular surface and MUC5AC alterations in atopic patients with corneal shield ulcers. Dogru M, etal., Curr Eye Res. 2005 Oct;30(10):897-908.
16. Mucin deficiency causes functional and structural changes of the ocular surface. Floyd AM, etal., PLoS One. 2012;7(12):e50704. doi: 10.1371/journal.pone.0050704. Epub 2012 Dec 18.
17. Spatial and temporal expression of CCR3 and the common beta chain of the IL-3, IL-5 and GM-CSF receptor in the nasal epithelium and lymphoid tissues in a rat model of allergic rhinitis. Fortin M, etal., Cytokine. 2010 Aug 7.
18. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
19. Effect of Bifidobacterium bifidum BF-1 on gastric protection and mucin production in an acute gastric injury rat model. Gomi A, etal., J Dairy Sci. 2013 Feb;96(2):832-7. doi: 10.3168/jds.2012-5950. Epub 2012 Nov 29.
20. Regulation of MUC5 and MUC1 gene expression: correlation with airway mucous differentiation. Guzman K, etal., Am J Physiol 1996 May;270(5 Pt 1):L846-53.
21. Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5. Hashimoto K, etal., Am J Respir Crit Care Med. 2004 Aug 1;170(3):306-12. Epub 2004 May 6.
22. Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection. Hasnain SZ, etal., Gastroenterology. 2010 May;138(5):1763-71. doi: 10.1053/j.gastro.2010.01.045. Epub 2010 Feb 4.
23. MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation. Henke MO, etal., Am J Respir Crit Care Med. 2007 Apr 15;175(8):816-21. Epub 2007 Jan 25.
24. Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-kappaB and EGFR pathways. Hewson CA, etal., Eur Respir J. 2010 Dec;36(6):1425-35. Epub 2010 Jun 4.
25. Cloning of rat Muc5AC mucin gene: comparison of its structure and tissue distribution to that of human and mouse homologues. Inatomi T, etal., Biochem Biophys Res Commun 1997 Jul 30;236(3):789-97.
26. Differences in the expression of mucins in various forms of cystitis glandularis. Jankovic Velickovic L, etal., Pathol Res Pract. 2007;203(9):653-8. Epub 2007 Jul 30.
27. MUC5AC expression in human middle ear epithelium of patients with otitis media. Kerschner JE, etal., Arch Otolaryngol Head Neck Surg. 2010 Aug;136(8):819-24. doi: 10.1001/archoto.2010.123.
28. Effects of normal saline and selenium-enriched hot spring water on experimentally induced rhinosinusitis in rats. Kim DH and Yeo SW, Int J Pediatr Otorhinolaryngol. 2013 Jan;77(1):117-22. doi: 10.1016/j.ijporl.2012.10.008. Epub 2012 Nov 3.
29. Panax ginseng ameliorates airway inflammation in an ovalbumin-sensitized mouse allergic asthma model. Kim DY and Yang WM, J Ethnopharmacol. 2011 Jun 14;136(1):230-5. doi: 10.1016/j.jep.2011.04.048. Epub 2011 Apr 28.
30. Relation of epidermal growth factor receptor expression to mucus hypersecretion in diffuse panbronchiolitis. Kim JH, etal., Chest. 2004 Sep;126(3):888-95.
31. Up-regulation of MUC5AC mRNA expression in endotoxin-induced otitis media. Kim YT, etal., Acta Otolaryngol. 2001 Apr;121(3):364-70.
32. Altered mucin gene expression in stone-containing intrahepatic bile ducts and cholangiocarcinomas. Lee KT and Liu TS, Dig Dis Sci. 2001 Oct;46(10):2166-72.
33. Effects of sulfur dioxide on the expressions of MUC5AC and ICAM-1 in airway of asthmatic rats. Li R, etal., Regul Toxicol Pharmacol. 2007 Aug;48(3):284-91. Epub 2007 May 21.
34. [Toll-like receptor 2 and Toll-like receptor 4 participates in mediation of acute otitis media and mortality in pneumococcal infections in mice]. Li SL, etal., Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Dec;46(12):1009-18.
35. A mouse dry eye model induced by topical administration of benzalkonium chloride. Lin Z, etal., Mol Vis. 2011 Jan 25;17:257-64.
36. The tear fluid mucin 5AC change of primary angle-closure glaucoma patients after short-term medications and phacotrabeculectomy. Liu W, etal., Mol Vis. 2010 Nov 9;16:2342-6.
37. Effects of dexamethasone on Muc5ac mucin production by primary airway goblet cells. Lu W, etal., Am J Physiol Lung Cell Mol Physiol. 2005 Jan;288(1):L52-60. Epub 2004 Sep 10.
38. [Expression of MUC5AC in human nasal polyp and inferior turbinate epithelium]. Lü H, etal., Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2004 Nov;18(11):649-50.
39. Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats. Mata M, etal., Eur Respir J. 2003 Dec;22(6):900-5.
40. MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer. Matull WR, etal., Br J Cancer. 2008 May 20;98(10):1675-81. Epub 2008 May 13.
41. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
42. Gastric mucosal protection via enhancement of MUC5AC and MUC6 by geranylgeranylacetone. Nam SY, etal., Dig Dis Sci. 2005 Nov;50(11):2110-20.
43. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
44. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
45. Comprehensive gene review and curation RGD comprehensive gene curation
46. Elastase- and LPS-exposed mice display altered responses to rhinovirus infection. Sajjan U, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L931-44. Epub 2009 Sep 11.
47. Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma. Shahzeidi S, etal., Exp Lung Res. 2003 Dec;29(8):549-65.
48. Mucin secretion in the rat tracheal epithelial cells by epidermal growth factor and Pseudomonas aeruginosa extracts. Song JS, etal., Korean J Intern Med. 2001 Sep;16(3):167-72.
49. Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca. Song XJ, etal., Invest Ophthalmol Vis Sci. 2003 Oct;44(10):4223-9.
50. Trefoil factor family 1, MUC5AC and human leucocyte antigen-DR expression by conjunctival cells in patients with glaucoma treated with chronic drugs: could these markers predict the success of glaucoma surgery? Souchier M, etal., Br J Ophthalmol. 2006 Nov;90(11):1366-9. Epub 2006 Jun 29.
51. The effect of formoterol on airway goblet cell hyperplasia and protein Muc5ac expression in asthmatic mice. Tan YF, etal., Eur Rev Med Pharmacol Sci. 2011 Jul;15(7):743-50.
52. Vitamin A deficiency alters the expression of mucin genes by the rat ocular surface epithelium. Tei M, etal., Invest Ophthalmol Vis Sci. 2000 Jan;41(1):82-8.
53. Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene. Tian C, etal., PLoS One. 2012;7(4):e34944. doi: 10.1371/journal.pone.0034944. Epub 2012 Apr 23.
54. Rapid and specific alterations of goblet cell mucin in rat airway and small intestine associated with resistance against Nippostrongylus brasiliensis reinfection. Tsubokawa D, etal., Exp Parasitol. 2012 Mar;130(3):209-17. doi: 10.1016/j.exppara.2012.01.002. Epub 2012 Jan 18.
55. Metaplasia of the duodenum shows a Helicobacter pylori-correlated differentiation into gastric-type protein expression. Van De Bovenkamp JH, etal., Hum Pathol. 2003 Feb;34(2):156-65.
56. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Viau S, etal., Graefes Arch Clin Exp Ophthalmol. 2009 Aug;247(8):1039-50. Epub 2009 May 5.
57. Gamma-tocopherol attenuates ozone-induced exacerbation of allergic rhinosinusitis in rats. Wagner JG, etal., Toxicol Pathol. 2009 Jun;37(4):481-91. doi: 10.1177/0192623309335630. Epub 2009 Apr 23.
58. Increased expression of human calcium-activated chloride channel 1 gene is correlated with mucus overproduction in Chinese asthmatic airway. Wang K, etal., Cell Biol Int. 2007 Nov;31(11):1388-95. Epub 2007 Jun 29.
59. Increased expression of human calcium-activated chloride channel 1 is correlated with mucus overproduction in the airways of Chinese patients with chronic obstructive pulmonary disease. Wang K, etal., Chin Med J (Engl). 2007 Jun 20;120(12):1051-7.
60. Mucin 5 subtype AC expression and upregulation in the nasal mucosa of allergic rhinitis rats. Wang W and Zheng M, Otolaryngol Head Neck Surg. 2012 Dec;147(6):1012-9. doi: 10.1177/0194599812460977. Epub 2012 Sep 12.
61. Ocular surface and tear functions after topical cyclosporine treatment in dry eye patients with chronic graft-versus-host disease. Wang Y, etal., Bone Marrow Transplant. 2008 Feb;41(3):293-302. Epub 2007 Nov 5.
62. Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas. Wang Y, etal., Int J Cancer. 2007 Dec 15;121(12):2716-22.
63. Expression and localization of MUC1, MUC2, MUC5AC and small intestinal mucin antigen in pancreatic tumors. Yamasaki H, etal., Int J Oncol. 2004 Jan;24(1):107-13.
64. Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor. Yonezawa S, etal., Pathol Int. 1999 Jan;49(1):45-54.
65. MUC19 expression in human ocular surface and lacrimal gland and its alteration in Sjogren syndrome patients. Yu DF, etal., Exp Eye Res. 2008 Feb;86(2):403-11. doi: 10.1016/j.exer.2007.11.013. Epub 2007 Nov 28.
66. The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Yue T, etal., Mol Cell Proteomics. 2009 Jul;8(7):1697-707. Epub 2009 Apr 17.
67. Analysis of the correlations of mucins, inflammatory markers, and clinical tests in dry eye. Zhang J, etal., Cornea. 2013 Jul;32(7):928-32. doi: 10.1097/ICO.0b013e3182801622.
Additional References at PubMed
PMID:11992401   PMID:14749330   PMID:15632090   PMID:16229173   PMID:17066439   PMID:17203232   PMID:17426222   PMID:19199708   PMID:19558866   PMID:21265101   PMID:22489685   PMID:22931723  
PMID:24975055   PMID:26850552   PMID:31170201   PMID:33300069   PMID:35908134  


Genomics

Comparative Map Data
Muc5ac
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,293,717 - 206,326,006 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1206,293,869 - 206,326,006 (+)EnsemblGRCr8
mRatBN7.21196,864,336 - 196,896,475 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,864,336 - 196,896,475 (+)EnsemblmRatBN7.2
Rnor_6.01214,725,482 - 214,756,653 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,727,416 - 214,741,252 (+)NCBIrn6Rnor6.0
Rnor_5.01221,642,507 - 221,671,770 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1194,493,496 - 194,524,940 (+)NCBICelera
Cytogenetic Map1q41NCBI
MUC5AC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,157,953 - 1,201,138 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,157,953 - 1,201,138 (+)Ensemblhg38GRCh38
GRCh37111,151,580 - 1,222,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,169,363 - 1,178,940 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34111,141,594 - 1,152,361NCBI
Celera111,216,270 - 1,325,135 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11979,261 - 1,006,024 (+)NCBIHuRef
CHM1_1111,141,384 - 1,221,279 (+)NCBICHM1_1
T2T-CHM13v2.0111,229,366 - 1,272,380 (+)NCBIT2T-CHM13v2.0
Muc5ac
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,342,695 - 141,372,964 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,342,709 - 141,372,968 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm387141,788,958 - 141,819,227 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,788,972 - 141,819,231 (+)Ensemblmm10GRCm38
MGSCv377148,974,916 - 149,005,040 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv367148,974,916 - 149,005,040 (+)NCBIMGSCv36mm8
Celera7141,544,129 - 141,573,772 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.23NCBI
Muc5ac
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547611,061,405 - 11,084,294 (-)NCBIChiLan1.0ChiLan1.0
MUC5AC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,571,337 - 3,614,623 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,783,098 - 2,826,292 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0111,191,223 - 1,234,373 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,225,362 - 1,272,411 (+)NCBIPanPan1.1PanPan1.1panPan2
MUC5AC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,471,232 - 45,498,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1844,080,267 - 44,110,233 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01846,149,914 - 46,180,208 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11845,598,266 - 45,628,540 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01845,178,618 - 45,208,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,916,410 - 45,946,691 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Muc5ac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947875,887 - 905,133 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936816129,926 - 159,026 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936816129,926 - 159,396 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MUC5AC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12757,897 - 790,321 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MUC5AC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11981,515 - 1,018,242 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603898,106,473 - 98,148,026 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Muc5ac
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,439,023 - 21,461,108 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Muc5ac
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v127,708,428 - 7,737,212 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Muc5ac
322 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:64
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000071485
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1181059071226059071Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1181059071226059071Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1182039247227039247Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1183564652228564652Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1181059071226059071Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1181059071226059071Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1182535316227535316Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1181059071226059071Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1181059071226059071Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1194786607207590403Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1203300512229359342Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1180739993225739993Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1191190115223964326Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1201915593208479939Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1178547286206690557Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1185979875230979875Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1202851915223964440Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1203300512213659238Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat

Markers in Region
D1Bda42  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21196,896,152 - 196,896,418 (+)MAPPERmRatBN7.2
Rnor_6.01214,756,331 - 214,756,596NCBIRnor6.0
Rnor_5.01221,671,448 - 221,671,713UniSTSRnor5.0
Celera1194,524,618 - 194,524,883UniSTS
RH141818  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21196,896,121 - 196,896,302 (+)MAPPERmRatBN7.2
Rnor_6.01214,756,300 - 214,756,480NCBIRnor6.0
Rnor_5.01221,671,417 - 221,671,597UniSTSRnor5.0
Celera1194,524,587 - 194,524,767UniSTS
RH 3.4 Map11437.21UniSTS


Expression

RNA-SEQ Expression

circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 20 23 39 31 7 13 8 15 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000085159   ⟹   ENSRNOP00000072033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1206,293,869 - 206,326,006 (+)Ensembl
mRatBN7.2 Ensembl1196,864,336 - 196,896,475 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091110   ⟹   ENSRNOP00000074773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1196,864,336 - 196,896,475 (+)Ensembl
RefSeq Acc Id: NM_001419868   ⟹   NP_001406797
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81206,293,869 - 206,326,006 (+)NCBI
mRatBN7.21196,864,336 - 196,896,475 (+)NCBI
RefSeq Acc Id: XM_063273781   ⟹   XP_063129851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81206,293,717 - 206,326,001 (+)NCBI
Ensembl Acc Id: ENSRNOP00000072033   ⟸   ENSRNOT00000085159
Ensembl Acc Id: ENSRNOP00000074773   ⟸   ENSRNOT00000091110
RefSeq Acc Id: NP_001406797   ⟸   NM_001419868
- Peptide Label: precursor
- UniProtKB: A0A0G2K1Y4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129851   ⟸   XM_063273781
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K8X5 (UniProtKB/TrEMBL)
Protein Domains
CTCK   VWFC   VWFD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K8X5-F1-model_v2 AlphaFold A0A0G2K8X5 1-1032 view protein structure
AF-A0A0G2K1Y4-F1-model_v2 AlphaFold A0A0G2K1Y4 1-1103 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62001 AgrOrtholog
BioCyc Gene G2FUF-56933 BioCyc
Ensembl Genes ENSRNOG00000055996 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000085159 ENTREZGENE
  ENSRNOT00000085159.3 UniProtKB/TrEMBL
Gene3D-CATH Complement Module, domain 1 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Cys_knot_C UniProtKB/TrEMBL
  Mucin_vWF_Thrombospondin_sf UniProtKB/TrEMBL
  Ser_inhib-like_sf UniProtKB/TrEMBL
  TIL_dom UniProtKB/TrEMBL
  Unchr_dom_Cys-rich UniProtKB/TrEMBL
  VWF_dom UniProtKB/TrEMBL
  VWF_type-D UniProtKB/TrEMBL
  WxxW_domain UniProtKB/TrEMBL
NCBI Gene Muc5ac ENTREZGENE
PANTHER EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED UniProtKB/TrEMBL
  MUCIN-5AC UniProtKB/TrEMBL
Pfam Mucin2_WxxW UniProtKB/TrEMBL
  PF08742 UniProtKB/TrEMBL
  TIL UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
PhenoGen Muc5ac PhenoGen
PROSITE CTCK_1 UniProtKB/TrEMBL
  CTCK_2 UniProtKB/TrEMBL
  VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
  VWFD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000055996 RatGTEx
SMART SM00041 UniProtKB/TrEMBL
  SM00832 UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/TrEMBL
  SSF57567 UniProtKB/TrEMBL
UniProt A0A0G2K1Y4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K8X5 ENTREZGENE
  O35888_RAT UniProtKB/TrEMBL
  Q9ESP3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Muc5ac  mucin 5AC, oligomeric mucus/gel-forming  AABR07006032.1    Data merged from RGD:15009889 737654 PROVISIONAL
2019-11-08 AABR07006032.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-09-19 Muc5ac  mucin 5AC, oligomeric mucus/gel-forming  LOC682837  similar to mucin 5, subtype B, tracheobronchial  Data merged from RGD:1594011 737654 APPROVED
2008-08-29 Muc5ac  mucin 5AC, oligomeric mucus/gel-forming  Muc5ac  mucin 5, subtypes A and C, tracheobronchial/gastric  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC682837  similar to mucin 5, subtype B, tracheobronchial      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Muc5ac  mucin 5, subtypes A and C, tracheobronchial/gastric    mucin 5, subtypes A and C  Name updated 1299863 APPROVED
2002-06-10 Muc5ac  mucin 5, subtypes A and C      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference