Cacna1g (calcium voltage-gated channel subunit alpha1 G) - Rat Genome Database

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Gene: Cacna1g (calcium voltage-gated channel subunit alpha1 G) Rattus norvegicus
Analyze
Symbol: Cacna1g
Name: calcium voltage-gated channel subunit alpha1 G
RGD ID: 68942
Description: Enables low voltage-gated calcium channel activity. Involved in several processes, including artery smooth muscle contraction; calcium ion transport; and cellular response to dexamethasone stimulus. Located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcium channel, voltage-dependent, T type, alpha 1G subunit; voltage-dependent T-type calcium channel subunit alpha-1G; voltage-gated calcium channel subunit alpha Cav3.1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Cacna1gm1Mcwi
Genetic Models: SS-Cacna1gm1Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81079,851,886 - 79,919,926 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)EnsemblGRCr8
mRatBN7.21079,354,998 - 79,422,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1079,355,008 - 79,422,752 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1083,959,837 - 84,027,483 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01083,457,956 - 83,525,607 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01078,972,823 - 79,040,417 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,129,071 - 82,197,828 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,129,506 - 82,197,848 (-)Ensemblrn6Rnor6.0
Rnor_5.01081,950,594 - 82,017,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41083,043,636 - 83,112,886 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1078,143,865 - 78,211,268 (-)NCBICelera
RGSC_v3.11083,058,005 - 83,127,256 (-)NCBI
RH 3.4 Map10617.6RGD
Cytogenetic Map10q26NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (EXP)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
allethrin  (EXP)
ammonium chloride  (EXP)
androgen antagonist  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
barium(0)  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (EXP)
C60 fullerene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calciol  (EXP)
calcium atom  (EXP,ISO)
calcium carbonate  (EXP)
calcium(0)  (EXP,ISO)
cannabidiol  (EXP)
cerium  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
Cuprizon  (EXP)
daunorubicin  (ISO)
DDE  (EXP)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzacamene  (EXP)
epoxiconazole  (EXP,ISO)
erbium  (ISO)
ethanol  (ISO)
fluoxetine  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gadolinium atom  (ISO)
genistein  (ISO)
holmium atom  (ISO)
indole-3-methanol  (EXP)
L-methionine  (ISO)
lanthanum atom  (ISO)
linuron  (EXP)
menadione  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
Mibefradil  (EXP,ISO)
mitoxantrone  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
neodymium atom  (ISO)
nickel atom  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP)
pentanal  (ISO)
permethrin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
potassium dichromate  (ISO)
prochloraz  (EXP)
procymidone  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
scandium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
tamoxifen  (ISO)
telmisartan  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
ytterbium  (ISO)
yttrium atom  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway   (ISO)
calcium transport pathway   (ISO)
calcium/calcium-mediated signaling pathway  (IEA,ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway   (ISO)
mitogen activated protein kinase signaling pathway  (IEA)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway   (ISO)
type 2 diabetes mellitus pathway  (IEA)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Regulation of T-type Cav3.1 channels expression by synthetic glucocorticoid dexamethasone in neonatal cardiac myocytes. BenMohamed F, etal., Mol Cell Biochem. 2009 Jan;320(1-2):173-83. Epub 2008 Sep 27.
2. Voltage-gated calcium channels. Catterall WA Cold Spring Harb Perspect Biol. 2011 Aug 1;3(8):a003947. doi: 10.1101/cshperspect.a003947.
3. Reversal of experimental neuropathic pain by T-type calcium channel blockers. Dogrul A, etal., Pain 2003 Sep;105(1-2):159-68.
4. Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels. Ferron L, etal., Circ Res. 2003 Dec 12;93(12):1241-8. Epub 2003 Nov 13.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels. Hansen PB, etal., Circ Res. 2001 Sep 28;89(7):630-8.
8. Temperature dependence of T-type calcium channel gating. Iftinca M, etal., Neuroscience. 2006 Nov 3;142(4):1031-42. Epub 2006 Aug 28.
9. Distinct contributions of different structural regions to the current kinetics of the Cav3.3 T-type Ca2+ channel. Kang HW, etal., Biochim Biophys Acta. 2008 Dec;1778(12):2740-8. Epub 2008 Aug 9.
10. Distribution of neurons expressing alpha 1G subunit mRNA of T-type voltage-dependent calcium channel in adult rat central nervous system. Kase M, etal., Neurosci Lett. 1999 Jun 18;268(2):77-80.
11. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
12. Expression of voltage-gated Ca2+ channel subtypes in cultured astrocytes. Latour I, etal., Glia 2003 Mar;41(4):347-53.
13. Ca(V)3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons. McKay BE, etal., Eur J Neurosci. 2006 Nov;24(9):2581-94.
14. Molecular and functional characterization of a family of rat brain T-type calcium channels. McRory JE, etal., J Biol Chem 2001 Feb 9;276(6):3999-4011.
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Non-L-type voltage-dependent calcium channels control vascular tone of the rat basilar artery. Navarro-Gonzalez MF, etal., Clin Exp Pharmacol Physiol. 2009 Jan;36(1):55-66. Epub 2008 Aug 26.
17. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
18. Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat. Obaid AA, etal., J Trace Elem Med Biol. 2023 May 24;79:127221. doi: 10.1016/j.jtemb.2023.127221.
19. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Perez-Reyes E, etal., Nature 1998 Feb 26;391(6670):896-900.
20. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
21. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
22. GOA pipeline RGD automated data pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
26. Cav3.1 (alpha1G) controls von Willebrand factor secretion in rat pulmonary microvascular endothelial cells. Zhou C, etal., Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L833-44. Epub 2006 Dec 15.
27. Cloning of a T-type Ca2+ channel isoform in insulin-secreting cells. Zhuang H, etal., Diabetes 2000 Jan;49(1):59-64.
Additional References at PubMed
PMID:11230107   PMID:16567615   PMID:16690884   PMID:17450521   PMID:17761775   PMID:18294617   PMID:18765948   PMID:18801335   PMID:18930057   PMID:19520861   PMID:19657020   PMID:19666840  
PMID:20505041   PMID:21084288   PMID:21123217   PMID:21148410   PMID:22972512   PMID:23103495   PMID:23250353   PMID:26456284   PMID:26656778   PMID:26715324   PMID:29578032   PMID:31871187  
PMID:32034930   PMID:34586897  


Genomics

Comparative Map Data
Cacna1g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81079,851,886 - 79,919,926 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)EnsemblGRCr8
mRatBN7.21079,354,998 - 79,422,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1079,355,008 - 79,422,752 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1083,959,837 - 84,027,483 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01083,457,956 - 83,525,607 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01078,972,823 - 79,040,417 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,129,071 - 82,197,828 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,129,506 - 82,197,848 (-)Ensemblrn6Rnor6.0
Rnor_5.01081,950,594 - 82,017,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41083,043,636 - 83,112,886 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1078,143,865 - 78,211,268 (-)NCBICelera
RGSC_v3.11083,058,005 - 83,127,256 (-)NCBI
RH 3.4 Map10617.6RGD
Cytogenetic Map10q26NCBI
CACNA1G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381750,560,715 - 50,627,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1750,560,715 - 50,627,474 (+)Ensemblhg38GRCh38
GRCh371748,638,076 - 48,704,835 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,993,448 - 46,059,541 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341745,993,447 - 46,038,832NCBI
Celera1745,099,811 - 45,165,917 (+)NCBICelera
Cytogenetic Map17q21.33NCBI
HuRef1744,006,381 - 44,072,836 (+)NCBIHuRef
CHM1_11748,702,306 - 48,768,826 (+)NCBICHM1_1
T2T-CHM13v2.01751,427,851 - 51,494,639 (+)NCBIT2T-CHM13v2.0
Cacna1g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,299,217 - 94,365,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,299,217 - 94,365,024 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381194,408,391 - 94,474,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,408,391 - 94,474,198 (-)Ensemblmm10GRCm38
MGSCv371194,269,705 - 94,335,512 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361194,224,606 - 94,289,815 (-)NCBIMGSCv36mm8
Celera11104,027,102 - 104,094,565 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1158.9NCBI
Cacna1g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,137,214 - 11,194,036 (-)Ensembl
ChiLan1.0NW_00495545111,136,885 - 11,194,321 (-)NCBIChiLan1.0ChiLan1.0
CACNA1G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,751,924 - 66,818,924 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11771,559,170 - 71,626,261 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,654,558 - 44,786,037 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11749,528,819 - 49,595,487 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,529,402 - 49,595,166 (+)EnsemblpanPan2panpan1.1
CACNA1G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,481,148 - 26,544,511 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,481,652 - 26,544,845 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha925,874,088 - 25,937,055 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0927,275,576 - 27,338,562 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl927,275,746 - 27,338,504 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1926,043,294 - 26,106,242 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0926,301,905 - 26,364,906 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0926,432,081 - 26,495,083 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cacna1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,917,385 - 25,981,187 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649011,093,595 - 11,157,563 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649011,093,600 - 11,157,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA1G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,844,079 - 26,912,110 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11226,838,633 - 26,912,344 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,991,543 - 27,052,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNA1G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11642,710,640 - 42,776,736 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1642,708,638 - 42,768,843 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607713,424,552 - 13,494,447 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacna1g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247956,443,781 - 6,501,050 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247956,443,322 - 6,501,673 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cacna1g
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1951,067,213 - 51,135,153 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cacna1g
745 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:68
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000055597, ENSRNOT00000067416
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)1079272424102982300Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395464802Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
724516Uae17Urinary albumin excretion QTL 173.6urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)107870758585720738Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106724133498502431Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)107369533997272278Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107304965694495280Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)107369533983061459Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)107369533983061459Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106413959783061459Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106184363383061236Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
2325836Bp346Blood pressure QTL 3460.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313384503487Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
12880053Cm104Cardiac mass QTL 1040.009heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)107395020983959619Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395604677Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Wox53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21079,361,543 - 79,361,708 (+)MAPPERmRatBN7.2
Rnor_6.01082,135,617 - 82,135,781NCBIRnor6.0
Rnor_5.01081,957,140 - 81,957,304UniSTSRnor5.0
RGSC_v3.41083,049,746 - 83,049,910UniSTSRGSC3.4
Celera1078,150,411 - 78,150,575UniSTS
Cytogenetic Map10q26-q31UniSTS
RH130173  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21079,355,437 - 79,355,617 (+)MAPPERmRatBN7.2
Rnor_6.01082,129,511 - 82,129,690NCBIRnor6.0
Rnor_5.01081,951,034 - 81,951,213UniSTSRnor5.0
RGSC_v3.41083,043,641 - 83,043,820UniSTSRGSC3.4
Celera1078,144,305 - 78,144,484UniSTS
RH 3.4 Map10631.2UniSTS
Cytogenetic Map10q26-q31UniSTS
RH142184  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81079,852,334 - 79,852,508 (+)Marker Load Pipeline
mRatBN7.21079,355,447 - 79,355,620 (+)MAPPERmRatBN7.2
Rnor_6.01082,129,521 - 82,129,693NCBIRnor6.0
Rnor_5.01081,951,044 - 81,951,216UniSTSRnor5.0
RGSC_v3.41083,043,651 - 83,043,823UniSTSRGSC3.4
Celera1078,144,315 - 78,144,487UniSTS
RH 3.4 Map10617.6UniSTS
Cytogenetic Map10q26-q31UniSTS
BE098192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21079,357,051 - 79,357,225 (+)MAPPERmRatBN7.2
Rnor_6.01082,131,125 - 82,131,298NCBIRnor6.0
Rnor_5.01081,952,648 - 81,952,821UniSTSRnor5.0
RGSC_v3.41083,045,255 - 83,045,428UniSTSRGSC3.4
Celera1078,145,919 - 78,146,092UniSTS
RH 3.4 Map10719.39UniSTS
Cytogenetic Map10q26-q31UniSTS
RH137526  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21079,355,442 - 79,355,563 (+)MAPPERmRatBN7.2
Rnor_6.01082,129,516 - 82,129,636NCBIRnor6.0
Rnor_5.01081,951,039 - 81,951,159UniSTSRnor5.0
RGSC_v3.41083,043,646 - 83,043,766UniSTSRGSC3.4
Celera1078,144,310 - 78,144,430UniSTS
Cytogenetic Map10q26-q31UniSTS
CACNA1G-1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81079,861,322 - 79,862,211 (+)Marker Load Pipeline
Rnor_5.01081,959,678 - 81,960,532NCBIRnor5.0
RGSC_v3.41083,052,735 - 83,053,623UniSTSRGSC3.4
Celera1078,153,302 - 78,154,190UniSTS
Cytogenetic Map10q26-q31UniSTS


Genetic Models
This gene Cacna1g is modified in the following models/strains:
SS-Cacna1gm1Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 85 210 91 90 59 76 59 6 408 204 22 188 114 124 31 34 34

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF027984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF125161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF203698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF290212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF116282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF116283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF116284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF116285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF116286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU293207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ227500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000081307   ⟹   ENSRNOP00000071940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,149 (-)Ensembl
mRatBN7.2 Ensembl1079,355,008 - 79,422,424 (-)Ensembl
Rnor_6.0 Ensembl1082,129,506 - 82,197,848 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092024   ⟹   ENSRNOP00000072061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)Ensembl
mRatBN7.2 Ensembl1079,355,008 - 79,422,424 (-)Ensembl
Rnor_6.0 Ensembl1082,129,541 - 82,197,520 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101230   ⟹   ENSRNOP00000095036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,852,618 - 79,919,634 (-)Ensembl
mRatBN7.2 Ensembl1079,355,730 - 79,422,752 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106180   ⟹   ENSRNOP00000080340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,149 (-)Ensembl
mRatBN7.2 Ensembl1079,355,008 - 79,422,267 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106257   ⟹   ENSRNOP00000091253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)Ensembl
mRatBN7.2 Ensembl1079,355,008 - 79,422,424 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115912   ⟹   ENSRNOP00000082604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)Ensembl
mRatBN7.2 Ensembl1079,355,008 - 79,422,424 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138373   ⟹   ENSRNOP00000104356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155882   ⟹   ENSRNOP00000109000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1079,851,896 - 79,919,634 (-)Ensembl
RefSeq Acc Id: NM_001308302   ⟹   NP_001295231
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,634 (-)NCBI
mRatBN7.21079,354,998 - 79,422,752 (-)NCBI
Rnor_6.01082,129,071 - 82,197,520 (-)NCBI
Celera1078,143,865 - 78,211,268 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031601   ⟹   NP_113789
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,634 (-)NCBI
mRatBN7.21079,354,998 - 79,422,752 (-)NCBI
Rnor_6.01082,129,071 - 82,197,520 (-)NCBI
Rnor_5.01081,950,594 - 82,017,885 (-)NCBI
RGSC_v3.41083,043,636 - 83,112,886 (-)RGD
Celera1078,143,865 - 78,211,268 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767985   ⟹   XP_008766207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,926 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,822 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767986   ⟹   XP_008766208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,926 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,822 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767987   ⟹   XP_008766209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,926 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,822 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767988   ⟹   XP_008766210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,926 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,822 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767994   ⟹   XP_008766216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767996   ⟹   XP_008766218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767997   ⟹   XP_008766219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767998   ⟹   XP_008766220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767999   ⟹   XP_008766221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768000   ⟹   XP_008766222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768001   ⟹   XP_008766223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,925 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597189   ⟹   XP_017452678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,851,886 - 79,919,926 (-)NCBI
mRatBN7.21079,354,998 - 79,422,960 (-)NCBI
Rnor_6.01082,129,071 - 82,197,821 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001295231 (Get FASTA)   NCBI Sequence Viewer  
  NP_113789 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766207 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766208 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766209 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766210 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766216 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766218 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766219 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766220 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766221 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766222 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766223 (Get FASTA)   NCBI Sequence Viewer  
  XP_017452678 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC67372 (Get FASTA)   NCBI Sequence Viewer  
  AAD26858 (Get FASTA)   NCBI Sequence Viewer  
  AAF26716 (Get FASTA)   NCBI Sequence Viewer  
  AAG35186 (Get FASTA)   NCBI Sequence Viewer  
  ABL63737 (Get FASTA)   NCBI Sequence Viewer  
  ABL63738 (Get FASTA)   NCBI Sequence Viewer  
  ABL63739 (Get FASTA)   NCBI Sequence Viewer  
  ABL63740 (Get FASTA)   NCBI Sequence Viewer  
  ABL63741 (Get FASTA)   NCBI Sequence Viewer  
  ABX89945 (Get FASTA)   NCBI Sequence Viewer  
  ABX89946 (Get FASTA)   NCBI Sequence Viewer  
  ABX89947 (Get FASTA)   NCBI Sequence Viewer  
  ABX89948 (Get FASTA)   NCBI Sequence Viewer  
  ABX89949 (Get FASTA)   NCBI Sequence Viewer  
  ABX89950 (Get FASTA)   NCBI Sequence Viewer  
  ACJ71730 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071940
  ENSRNOP00000072061
  ENSRNOP00000082604
  ENSRNOP00000091253
  ENSRNOP00000104356
GenBank Protein O54898 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113789   ⟸   NM_031601
- Peptide Label: isoform 2
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot),   A6HI48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766222   ⟸   XM_008768000
- Peptide Label: isoform X11
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766223   ⟸   XM_008768001
- Peptide Label: isoform X12
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766221   ⟸   XM_008767999
- Peptide Label: isoform X10
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766210   ⟸   XM_008767988
- Peptide Label: isoform X4
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766219   ⟸   XM_008767997
- Peptide Label: isoform X8
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766220   ⟸   XM_008767998
- Peptide Label: isoform X9
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766208   ⟸   XM_008767986
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZVK1 (UniProtKB/TrEMBL),   A0A8I5ZQG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766218   ⟸   XM_008767996
- Peptide Label: isoform X7
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot),   A0A0G2K1Q5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766209   ⟸   XM_008767987
- Peptide Label: isoform X3
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766216   ⟸   XM_008767994
- Peptide Label: isoform X6
- UniProtKB: A0A0G2K209 (UniProtKB/TrEMBL),   A0A8I5ZQG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766207   ⟸   XM_008767985
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZQG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295231   ⟸   NM_001308302
- Peptide Label: isoform 1
- UniProtKB: Q9WUB8 (UniProtKB/TrEMBL),   A0A8I5ZQG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452678   ⟸   XM_017597189
- Peptide Label: isoform X5
- UniProtKB: Q548R1 (UniProtKB/Swiss-Prot),   O54898 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072061   ⟸   ENSRNOT00000092024
Ensembl Acc Id: ENSRNOP00000071940   ⟸   ENSRNOT00000081307
Ensembl Acc Id: ENSRNOP00000091253   ⟸   ENSRNOT00000106257
Ensembl Acc Id: ENSRNOP00000082604   ⟸   ENSRNOT00000115912
Ensembl Acc Id: ENSRNOP00000095036   ⟸   ENSRNOT00000101230
Ensembl Acc Id: ENSRNOP00000080340   ⟸   ENSRNOT00000106180
Ensembl Acc Id: ENSRNOP00000104356   ⟸   ENSRNOT00000138373
Ensembl Acc Id: ENSRNOP00000109000   ⟸   ENSRNOT00000155882
Protein Domains
Ion transport

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54898-F1-model_v2 AlphaFold O54898 1-2254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697605
Promoter ID:EPDNEW_R8127
Type:initiation region
Name:Cacna1g_1
Description:calcium voltage-gated channel subunit alpha1 G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01082,197,810 - 82,197,870EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68942 AgrOrtholog
BioCyc Gene G2FUF-23622 BioCyc
Ensembl Genes ENSRNOG00000060528 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000081307 ENTREZGENE
  ENSRNOT00000092024 ENTREZGENE
  ENSRNOT00000106257 ENTREZGENE
  ENSRNOT00000115912 ENTREZGENE
  ENSRNOT00000138373 ENTREZGENE
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
  1.20.120.350 UniProtKB/Swiss-Prot
InterPro Ion_trans_dom UniProtKB/Swiss-Prot
  VDCC_alpha-1_subunit UniProtKB/Swiss-Prot
  VDCC_T_a1 UniProtKB/Swiss-Prot
  Volt_channel_dom_sf UniProtKB/Swiss-Prot
NCBI Gene 29717 ENTREZGENE
PANTHER VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 UniProtKB/Swiss-Prot
  VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1G UniProtKB/Swiss-Prot
Pfam Ion_trans UniProtKB/Swiss-Prot
PharmGKB CACNA1G RGD
PhenoGen Cacna1g PhenoGen
PRINTS TVDCCALPHA1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060528 RatGTEx
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/Swiss-Prot
TIGR TC218456
UniProt A0A0G2K1Q5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K209 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIV4_RAT UniProtKB/TrEMBL
  A0A8I6GKZ6_RAT UniProtKB/TrEMBL
  A0ABK0L4A7_RAT UniProtKB/TrEMBL
  A0ABK0LDZ6_RAT UniProtKB/TrEMBL
  A1EA75_RAT UniProtKB/TrEMBL
  A6HI48 ENTREZGENE, UniProtKB/TrEMBL
  A9YTJ4_RAT UniProtKB/TrEMBL
  A9YTJ5_RAT UniProtKB/TrEMBL
  A9YTJ6_RAT UniProtKB/TrEMBL
  A9YTJ7_RAT UniProtKB/TrEMBL
  A9YTJ8_RAT UniProtKB/TrEMBL
  A9YTJ9_RAT UniProtKB/TrEMBL
  B8XCX0_RAT UniProtKB/TrEMBL
  CAC1G_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q548R1 ENTREZGENE
  Q9JL92_RAT UniProtKB/TrEMBL
  Q9WUB8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q548R1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Cacna1g  calcium voltage-gated channel subunit alpha1 G  Cacna1g  calcium channel, voltage-dependent, T type, alpha 1G subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Cacna1g  calcium channel, voltage-dependent, T type, alpha 1G subunit      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the plasma membrane of astrocytes 727502
gene_expression expressed throughout the newborn and juvenile brain 62421
gene_expression expressed in cultured astrocytes 727502
gene_expression expressed in amygdala, cerebellum and thalamus 68747
gene_process mediates voltage-dependent entry of calcium into nerve, muscle, and endocrine cells 68748
gene_process responsible for central neuron rebound burst firing and implicated in slow wave sleep and epilepsy 68748
gene_process may play a role in hormone secretion and smooth muscle excitability 68748
gene_process may be involved in pacemaker activity, neuronal oscillations and resonance 68747