Gene:	Cacna1g ( Rattus norvegicus ) calcium channel, voltage-dependent, T type, alpha 1G subunit
Description:	low voltage-activated calcium channel alpha subunit; involved in calcium ion transport in nerve, muscle and edocrine cells
ArrayIDs:	6702752; 5857958; 6665000; 6466805; 6379039; 6563976; 6601769; 6745010; 5671228; 6404857; 5630099; 5819741; 6380409; 5828880; 6632218; 6061037; 6042980; 6322224; 5844991; 6284105; 6364162; 5806314; 5637925; 5971305; 5774311; 1370508_a_at; 5903436; 5997497; 5695895; 6359912; rc_AA963220_at; 6402725; AF027984_at; 5978946; 6102018; 6566095; 6121770; 6643904; 5725259; 6661155; 6028457; 6661966; 6732425; 5866318; 6240238; 6181262; 6545154; 6059214;  (details...)
Gene Type:	protein-coding
Additional Data
Curated Variants:	Cacna1gm1Mcwi
primer pair:	634953
Homologs
Homo sapiens: CACNA1G     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Cacna1g     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Cacna1g genome assembly 3.1 10 83058005 - 83127256     Rat Celera Assembly 10 78144300 - 78211596     RH 3.4 10 617.6     RGSC genome assembly v3.4 10 83043636 - 83112886     Cytogenetic 10 q26-q31 Mus musculus Cacna1g Mouse genome assembly build 36.1 11 94269830 - 94335039     Cytogenetic 11 11 D Homo sapiens CACNA1G human genome assembly 17 45993447 - 46038832     Human genome assembly build 36.2 17 45993448 - 46059541     Cytogenetic 17 q22   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology voltage-gated calcium channel activity,  ion channel activity,  low voltage-gated calcium channel activity ...  (details...)
Biological Process	Note Reference may be involved in pacemaker activity, neuronal oscillations and resonance 68747 mediates voltage-dependent entry of calcium into nerve, muscle, and endocrine cells 68748 responsible for central neuron rebound burst firing and implicated in slow wave sleep and epilepsy 68748 may play a role in hormone secretion and smooth muscle excitability 68748 Gene Ontology elevation of cytosolic calcium ion concentration,  regulation of heart rate,  artery smooth muscle contraction ...  (details...)
Cellular Component	Note Reference localizes to the plasma membrane of astrocytes 727502 Gene Ontology perinuclear region of cytoplasm,  voltage-gated calcium channel complex,  cell soma ...  (details...)
Disease	Ontology Epilepsy, Absence,  Diabetes Mellitus, Insulin-Dependent (details...)
Phenotype	Ontology abnormal circulating insulin level (details...)
Expression	Note Reference expressed in cultured astrocytes 727502 expressed in amygdala, cerebellum and thalamus 68747 expressed throughout the newborn and juvenile brain 62421
External Links
Databases	DATABASE ID SOURCE UNIPARC: UPI0000DC1C23 IPI UNIPARC: UPI0000DC1C25 IPI UNIPARC: UPI0001B7A5BA IPI UNIPARC: UPI0000500E87 IPI UNIPARC: UPI0001B7A5B9 IPI UNIPARC: UPI0000DC1C22 IPI KEGG Report: rno:29717 ENTREZGENE HomoloGene Group ID: 22544 ENTREZGENE Germonline: 68942 Pfam: Ion_trans IPI KEGG Pathway: 04020 ENTREZGENE KEGG Pathway: 04930 ENTREZGENE KEGG Pathway: 04010 ENTREZGENE InterPro: Ion_trans. IPI InterPro: VDCCAlpha1. IPI InterPro: VDCC_T_a1su. IPI IPI: IPI00196758 IPI IPI: IPI00779802 IPI IPI: IPI00199192 IPI IPI: IPI00339110 IPI IPI: IPI00777235 IPI IPI: IPI00950405 IPI Ensembl Protein: ENSRNOP00000046908 IPI Ensembl Protein: ENSRNOP00000004004 IPI Ensembl Protein: ENSRNOP00000052460 IPI Ensembl Protein: ENSRNOP00000049796 IPI Ensembl Protein: ENSRNOP00000061436 IPI Ensembl Protein: ENSRNOP00000052461 IPI Entrez Gene: Cacna1g ENTREZGENE TIGR: TC218456 UniProt: Q9WUB8_RAT IPI UniProt: Q9JL92_RAT IPI UniProt: A1EA76_RAT IPI UniProt: A1EA77_RAT IPI UniProt: A9YTJ5_RAT IPI UniProt: A1EA78_RAT IPI UniProt: A9YTJ6_RAT IPI UniProt: A9YTJ7_RAT IPI UniProt: A9YTJ8_RAT IPI UniProt: CAC1G_RAT IPI UniProt: A1EA74_RAT IPI UniProt: A9YTJ4_RAT IPI UniProt: A9YTJ9_RAT IPI Ensembl Genes: ENSRNOG00000002981 IPI PANTHER: TVDCCAlpha1 IPI PRINTS: TVDCCALPHA1. IPI PRINTS: CACHANNEL. IPI
Sequences	Nucleotide: AF290212 Get FASTA Search GEO Profiles Nucleotide: EF116282 Get FASTA Search GEO Profiles Nucleotide: EF116283 Get FASTA Search GEO Profiles Nucleotide: EF116284 Get FASTA Search GEO Profiles Nucleotide: EF116285 Get FASTA Search GEO Profiles Nucleotide: EF116286 Get FASTA Search GEO Profiles Nucleotide: EU293202 Get FASTA Search GEO Profiles Nucleotide: EU293203 Get FASTA Search GEO Profiles Nucleotide: EU293204 Get FASTA Search GEO Profiles Nucleotide: EU293205 Get FASTA Search GEO Profiles Nucleotide: EU293206 Get FASTA Search GEO Profiles Nucleotide: EU293207 Get FASTA Search GEO Profiles Nucleotide: AF203698 Get FASTA Search GEO Profiles Nucleotide: AF125161 Get FASTA Search GEO Profiles Nucleotide: AF027984 Get FASTA Search GEO Profiles Nucleotide: FJ227500 Get FASTA Search GEO Profiles Nucleotide: NM_031601 Get FASTA Search GEO Profiles (View all 17 Nucleotide Accessions) Protein: O54898 Get FASTA Protein: ACJ71730 Get FASTA Protein: ABX89950 Get FASTA Protein: ABX89949 Get FASTA Protein: ABX89948 Get FASTA Protein: ABX89947 Get FASTA Protein: ABX89946 Get FASTA Protein: ABX89945 Get FASTA Protein: ABL63741 Get FASTA Protein: ABL63740 Get FASTA Protein: ABL63739 Get FASTA Protein: ABL63738 Get FASTA Protein: ABL63737 Get FASTA Protein: AAG35186 Get FASTA Protein: Q9WUB8 Get FASTA Protein: Q9JL92 Get FASTA Protein: AAD26858 Get FASTA Protein: AAC67372 Get FASTA Protein: AAF26716 Get FASTA Protein: NP_113789 Get FASTA (View all 20 Protein Accessions)
Clusters	UniGene: 86960
References
Curated References	15 references in RGD related to Cacna1g
Other References	18 other references at PubMed related to Cacna1g
Database Information
RGD ID	68942
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-JUN-02: Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit APPROVED Symbol and Name status set to approved 70586