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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68942 Species: Rattus norvegicus RGD Object: Gene Symbol: Cacna1g Name: calcium channel, voltage-dependent, T type, alpha 1G subunit

Acc ID: CHEBI:34795 Term: 3-isobutyl-1-methyl-7H-xanthine Definition: A 3-isobutyl-1-methylxanthine that has formula C10H14N4O2. CasRN: 28822-58-4 Chemical ID: MESH:D015056

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Mibefradil inhibits the reaction [[Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein] Nickel inhibits the reaction [[Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]	PMID:17110049