Gene:	Csf2 ( Rattus norvegicus ) colony stimulating factor 2 (granulocyte-macrophage)
Description:	plays a role in alveolar epithelial fluid transport
Synonyms:	Gm-csf; Gmcsf;
ArrayIDs:	6435475; 1371228_at; 6129578; 1371227_at; 6248324; 6120161; GE20831; 6452788; A_43_P16294; A_44_P247880; 5852468;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CSF2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Csf2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Csf2 Rat Celera Assembly 10 37727629 - 37729611     RGSC genome assembly v3.4 10 39665850 - 39667831     Cytogenetic 10 q22     genome assembly 3.1 10 39679472 - 39681403 Mus musculus Csf2 Mouse genome assembly build 36.1 11 54060772 - 54063401     Cytogenetic 11 11 B1.3 Homo sapiens CSF2 human genome assembly 5 131437383 - 131439758     Human genome assembly build 36.2 5 131437384 - 131439758     Cytogenetic 5 q31.1   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding,  growth factor activity,  granulocyte macrophage colony-stimulating factor receptor binding ...  (details...)
Biological Process	Gene Ontology regulation of gene expression,  positive regulation of macrophage differentiation,  immune response ...  (details...)
Cellular Component	Gene Ontology extracellular space,  extracellular region (details...)
External Links
Databases	DATABASE ID SOURCE SMART: CSF2 IPI PROSITE: GM_CSF IPI ProDom: GM_colony-stim-fac IPI UNIPARC: UPI0000DA339B IPI KEGG Report: rno:116630 ENTREZGENE HomoloGene Group ID: 600 ENTREZGENE Germonline: 621065 Pfam: GM_CSF IPI KEGG Pathway: 04640 ENTREZGENE KEGG Pathway: 04664 ENTREZGENE KEGG Pathway: 04060 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 04630 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE InterPro: GM_colony-stim-fac. IPI InterPro: 4_helix_cytokine-like_core. IPI InterPro: 4_helix_cytokine_core. IPI Ensembl Protein: ENSRNOP00000034235 IPI IPI: IPI00372574 IPI Gene3D-CATH: 4_helix_cytokine_core IPI Entrez Gene: Csf2 ENTREZGENE UniProt: CSF2_RAT IPI Ensembl Genes: ENSRNOG00000026805 IPI Superfamily-SCOP: 4_helix_cytokine IPI PANTHER: GM_CSF IPI PRINTS: GMCSFACTOR. IPI
Sequences	Nucleotide: XM_001074265 Get FASTA Search GEO Profiles Nucleotide: CH473948 Get FASTA Search GEO Profiles Nucleotide: XM_340799 Get FASTA Search GEO Profiles Nucleotide: U00620 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: XP_340800 Get FASTA Protein: AAA18281 Get FASTA Protein: P48750 Get FASTA Protein: EDM04426 Get FASTA Protein: XP_001074265 Get FASTA (View all 5 Protein Accessions)
Clusters	UniGene: 44285
References
Curated References	5 references in RGD related to Csf2
Other References	13 other references at PubMed related to Csf2
Database Information
RGD ID	621065
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-SEP-04: Csf2 colony stimulating factor 2 (granulocyte-macrophage) APPROVED Symbol and Name status set to approved 1299863 07-AUG-02: Csf2 colony stimulating factor 2 (granulocyte-macrophage) PROVISIONAL Symbol and Name status set to provisional 70820