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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621065
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf2
Name: colony stimulating factor 2
Acc ID: CHEBI:8005
Term: peptidoglycan
Definition: A peptidoglycosaminoglycan formed by alternating residues of beta-(1->4)-linked N-acetylglucosamine and N-acetylmuramic acid {2-amino-3-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose} residues. Attached to the carboxy group of the muramic acid is a peptide chain of three to five amino acids.
Chemical ID: MESH:D010457
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf2increases expressionISOCSF2 (Homo sapiens)6480464CTDPeptidoglycan results in increased expression of CSF2 mRNA; Peptidoglycan results in increased expression of CSF2 proteinPMID:12574323 PMID:15191912
Csf2multiple interactionsISOCSF2 (Homo sapiens)6480464CTDCSF2 protein promotes the reaction [Peptidoglycan results in increased secretion of CXCL8 protein]PMID:12176910
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