Pafah1b1 (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1) - Rat Genome Database

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Gene: Pafah1b1 (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1) Rattus norvegicus
Analyze
Symbol: Pafah1b1
Name: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
RGD ID: 620331
Description: Enables dynein intermediate chain binding activity. Involved in several processes, including establishment of centrosome localization; generation of neurons; and regulation of neuron projection development. Located in several cellular components, including central region of growth cone; neuronal cell body; and nuclear envelope. Part of 1-alkyl-2-acetylglycerophosphocholine esterase complex and kinesin complex. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in lissencephaly and lissencephaly 1. Orthologous to human PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ether lipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LIS-1; LIS1; lissencephaly-1 protein; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAF-AH beta; PAFAH alpha; platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,031,441 - 60,090,259 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1060,032,514 - 60,090,196 (-)EnsemblGRCr8
mRatBN7.21059,533,042 - 59,591,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,534,117 - 59,591,808 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1064,180,143 - 64,238,014 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,685,733 - 63,743,607 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,148,104 - 59,205,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,456,144 - 61,577,412 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,456,145 - 61,577,412 (-)Ensemblrn6Rnor6.0
Rnor_5.01061,186,183 - 61,299,247 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41061,955,348 - 62,037,871 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1058,565,530 - 58,623,461 (-)NCBICelera
RGSC_v3.11061,968,971 - 62,051,494 (-)NCBI
Cytogenetic Map10q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Apafant  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
castor oil  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glucose  (ISO)
inulin  (ISO)
isosorbide mononitrate  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosphatidylcholine  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
terbutaline  (EXP)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acrosome assembly  (ISO)
actin cytoskeleton organization  (ISO)
adult locomotory behavior  (IEA,ISO)
ameboidal-type cell migration  (ISO)
auditory receptor cell development  (IEA,ISO)
brain morphogenesis  (IBA,IEA,ISO)
cell differentiation  (IEA)
cell division  (IEA)
cell migration  (ISO)
centrosome localization  (IEA)
cerebral cortex development  (IEA,ISO)
cerebral cortex neuron differentiation  (IMP)
chemical synaptic transmission  (ISO)
cochlea development  (IEA,ISO)
corpus callosum morphogenesis  (IEA,ISO)
cortical microtubule organization  (IEA,ISO)
establishment of centrosome localization  (IMP)
establishment of mitotic spindle orientation  (IBA,IEA,ISO)
establishment of organelle localization  (IEA)
establishment of planar polarity of embryonic epithelium  (IEA,ISO)
forebrain development  (IEA)
germ cell development  (IBA)
hippocampus development  (ISO)
layer formation in cerebral cortex  (ISO)
learning or memory  (ISO)
lipid catabolic process  (IEA)
lipid metabolic process  (IEA)
maintenance of centrosome location  (ISO)
microtubule cytoskeleton organization  (ISO)
microtubule cytoskeleton organization involved in establishment of planar polarity  (IEA,ISO)
microtubule organizing center organization  (IBA,IEA,ISO)
microtubule sliding  (IEA)
microtubule-based process  (IEA,ISO)
modulation of chemical synaptic transmission  (IEA,ISO)
negative regulation of JNK cascade  (ISO)
negative regulation of neuron projection development  (IMP)
nervous system development  (IEA)
neuroblast proliferation  (ISO)
neuromuscular process controlling balance  (IEA,ISO)
neuron migration  (IEA,IMP,ISO)
nuclear membrane disassembly  (ISO)
nuclear migration  (IBA,IMP)
osteoclast development  (ISO)
positive regulation of axon extension  (IMP)
positive regulation of cellular component organization  (IEA,ISO)
positive regulation of cytokine-mediated signaling pathway  (ISO)
positive regulation of dendritic spine morphogenesis  (IEA,ISO)
positive regulation of embryonic development  (IEA,ISO)
positive regulation of mitotic cell cycle  (IMP)
protein secretion  (ISO)
reelin-mediated signaling pathway  (IEA,ISO,ISS)
regulation of microtubule cytoskeleton organization  (IEA,ISO)
regulation of postsynapse organization  (IEA,ISO)
retrograde axonal transport  (IBA,ISO)
stem cell division  (IMP)
transmission of nerve impulse  (ISO)
vesicle transport along microtubule  (IBA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The role of DCX and LIS1 in migration through the lateral cortical stream of developing forebrain. Bai J, etal., Dev Neurosci. 2008;30(1-3):144-56.
2. The location and type of mutation predict malformation severity in isolated lissencephaly caused by abnormalities within the LIS1 gene. Cardoso C, etal., Hum Mol Genet. 2000 Dec 12;9(20):3019-28.
3. Interaction between LIS1 and doublecortin, two lissencephaly gene products. Caspi M, etal., Hum Mol Genet. 2000 Sep 22;9(15):2205-13.
4. A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Faulkner NE, etal., Nat Cell Biol. 2000 Nov;2(11):784-91.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. Grabham PW, etal., J Neurosci. 2007 May 23;27(21):5823-34.
8. [A rare case of ileo-ileal intussusception secondary to adenocarcinoma of the small intestine in a 21-year-old adult] Guarda PG and Vitale M, Minerva Chir. 1991 Sep 30;46(18):985-7.
9. Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. Hebbar S, etal., J Cell Biol. 2008 Sep 22;182(6):1063-71. doi: 10.1083/jcb.200803071.
10. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Lipska BK, etal., Hum Mol Genet. 2006 Apr 15;15(8):1245-58. Epub 2006 Mar 1.
11. Switching of platelet-activating factor acetylhydrolase catalytic subunits in developing rat brain. Manya H, etal., J Biol Chem. 1998 Jul 17;273(29):18567-72.
12. The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. Morris SM, etal., Curr Biol. 1998 May 7;8(10):603-6.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. Impaired learning and motor behavior in heterozygous Pafah1b1 (Lis1) mutant mice. Paylor R, etal., Learn Mem. 1999 Sep-Oct;6(5):521-37.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
18. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Pletnikov MV, etal., Neurosci Res. 2007 Jul;58(3):234-44. Epub 2007 Mar 16.
19. GOA pipeline RGD automated data pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Platelet-activating factor (PAF) acetylhydrolase activity, LIS1 expression, and seizures. Shmueli O, etal., J Neurosci Res. 1999 Jul 15;57(2):176-84.
23. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Smith DS, etal., Nat Cell Biol. 2000 Nov;2(11):767-75.
24. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
25. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Taya S, etal., J Neurosci. 2007 Jan 3;27(1):15-26.
26. LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages. Tsai JW, etal., J Cell Biol. 2005 Sep 12;170(6):935-45. Epub 2005 Sep 6.
27. Dual subcellular roles for LIS1 and dynein in radial neuronal migration in live brain tissue. Tsai JW, etal., Nat Neurosci. 2007 Aug;10(8):970-9. Epub 2007 Jul 8.
28. Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase. Watanabe M, etal., Biochim Biophys Acta 1998 Jan 2;1401(1):73-9.
29. The human LIS1 is downregulated in hepatocellular carcinoma and plays a tumor suppressor function. Xing Z, etal., Biochem Biophys Res Commun. 2011 Jun 3;409(2):193-9. doi: 10.1016/j.bbrc.2011.04.117. Epub 2011 May 1.
30. The Pafah1b complex interacts with the reelin receptor VLDLR. Zhang G, etal., PLoS One. 2007 Feb 28;2(2):e252.
Additional References at PubMed
PMID:9063735   PMID:9697693   PMID:10729324   PMID:11163258   PMID:11163259   PMID:11163260   PMID:11344260   PMID:11889140   PMID:11940666   PMID:12551946   PMID:12629176   PMID:12796778  
PMID:12950100   PMID:13129914   PMID:14507966   PMID:14578885   PMID:14691133   PMID:15331402   PMID:15489334   PMID:16107726   PMID:16481446   PMID:17314247   PMID:17433713   PMID:18469343  
PMID:19056867   PMID:21212011   PMID:21399614   PMID:21844209   PMID:21911489   PMID:22073305   PMID:22871113   PMID:23483716   PMID:23533177   PMID:23551859   PMID:28000671   PMID:28131823  
PMID:28576829   PMID:31505169  


Genomics

Comparative Map Data
Pafah1b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,031,441 - 60,090,259 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1060,032,514 - 60,090,196 (-)EnsemblGRCr8
mRatBN7.21059,533,042 - 59,591,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,534,117 - 59,591,808 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1064,180,143 - 64,238,014 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,685,733 - 63,743,607 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,148,104 - 59,205,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,456,144 - 61,577,412 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,456,145 - 61,577,412 (-)Ensemblrn6Rnor6.0
Rnor_5.01061,186,183 - 61,299,247 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41061,955,348 - 62,037,871 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1058,565,530 - 58,623,461 (-)NCBICelera
RGSC_v3.11061,968,971 - 62,051,494 (-)NCBI
Cytogenetic Map10q24NCBI
PAFAH1B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,593,183 - 2,685,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,593,183 - 2,685,616 (+)Ensemblhg38GRCh38
GRCh37172,496,948 - 2,588,909 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,443,686 - 2,535,638 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34172,443,685 - 2,535,638NCBI
Celera172,513,612 - 2,605,584 (+)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef172,389,423 - 2,481,264 (+)NCBIHuRef
CHM1_1172,505,702 - 2,597,647 (+)NCBICHM1_1
T2T-CHM13v2.0172,482,370 - 2,574,760 (+)NCBIT2T-CHM13v2.0
Pafah1b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,564,775 - 74,615,210 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,564,775 - 74,615,496 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381174,673,949 - 74,724,384 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,673,949 - 74,724,670 (-)Ensemblmm10GRCm38
MGSCv371174,487,452 - 74,537,886 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361174,490,150 - 74,540,865 (-)NCBIMGSCv36mm8
Celera1182,183,768 - 82,236,827 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
Pafah1b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955481608,897 - 686,452 (-)Ensembl
ChiLan1.0NW_004955481608,897 - 686,454 (-)NCBIChiLan1.0ChiLan1.0
PAFAH1B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21910,173,698 - 10,266,800 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11712,140,607 - 12,233,244 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,584,349 - 2,676,928 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,589,129 - 2,680,994 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,590,007 - 2,680,994 (+)EnsemblpanPan2panpan1.1
PAFAH1B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1946,648,057 - 46,731,259 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl946,648,052 - 46,771,400 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha945,800,900 - 45,884,016 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0947,482,963 - 47,566,431 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl947,482,963 - 47,607,125 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,250,595 - 46,333,659 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,544,618 - 46,627,828 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,599,366 - 46,680,302 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pafah1b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,734,221 - 45,815,751 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365388,612,049 - 8,694,015 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365388,612,142 - 8,693,698 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAFAH1B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,628,816 - 48,735,834 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11248,567,329 - 48,735,836 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21250,398,376 - 50,505,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAFAH1B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,270,126 - 2,293,705 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl162,270,085 - 2,296,825 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605919,649,125 - 19,755,407 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pafah1b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247865,224,982 - 5,302,436 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247865,223,890 - 5,306,033 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pafah1b1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1993,406,083 - 93,464,249 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pafah1b1
280 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:967
Count of miRNA genes:330
Interacting mature miRNAs:441
Transcripts:ENSRNOT00000003696
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104748901769161158Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105216243375582749Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105686844076129113Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105429622767476781Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
RH130886  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21059,534,835 - 59,535,036 (+)MAPPERmRatBN7.2
Rnor_6.01061,457,936 - 61,458,136NCBIRnor6.0
Rnor_5.01061,186,903 - 61,187,103UniSTSRnor5.0
RGSC_v3.41061,956,068 - 61,956,268UniSTSRGSC3.4
Celera1058,566,250 - 58,566,450UniSTS
Cytogenetic Map10q24UniSTS
RH134247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21059,534,178 - 59,534,358 (+)MAPPERmRatBN7.2
Rnor_6.01061,457,279 - 61,457,458NCBIRnor6.0
Rnor_5.01061,186,246 - 61,186,425UniSTSRnor5.0
RGSC_v3.41061,955,411 - 61,955,590UniSTSRGSC3.4
Celera1058,565,593 - 58,565,772UniSTS
Cytogenetic Map10q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003696   ⟹   ENSRNOP00000003696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1060,032,514 - 60,090,196 (-)Ensembl
mRatBN7.2 Ensembl1059,534,117 - 59,591,808 (-)Ensembl
Rnor_6.0 Ensembl1061,457,216 - 61,577,412 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1061,459,741 - 61,460,462 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092712   ⟹   ENSRNOP00000075779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1061,456,145 - 61,576,952 (-)Ensembl
RefSeq Acc Id: NM_031763   ⟹   NP_113951
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,032,513 - 60,090,196 (-)NCBI
mRatBN7.21059,534,116 - 59,591,808 (-)NCBI
Rnor_6.01061,457,216 - 61,577,412 (-)NCBI
Rnor_5.01061,186,183 - 61,299,247 (-)NCBI
RGSC_v3.41061,955,348 - 62,037,871 (-)RGD
Celera1058,565,530 - 58,623,461 (-)RGD
Sequence:
RefSeq Acc Id: XM_039086944   ⟹   XP_038942872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,089,869 (-)NCBI
mRatBN7.21059,533,042 - 59,591,338 (-)NCBI
RefSeq Acc Id: XM_063269963   ⟹   XP_063126033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,090,250 (-)NCBI
RefSeq Acc Id: XM_063269964   ⟹   XP_063126034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,090,259 (-)NCBI
RefSeq Acc Id: XM_063269965   ⟹   XP_063126035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,089,735 (-)NCBI
RefSeq Acc Id: XM_063269966   ⟹   XP_063126036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,089,723 (-)NCBI
RefSeq Acc Id: XM_063269967   ⟹   XP_063126037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,090,250 (-)NCBI
RefSeq Acc Id: XM_063269968   ⟹   XP_063126038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,089,723 (-)NCBI
RefSeq Acc Id: XM_063269969   ⟹   XP_063126039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,031,441 - 60,078,031 (-)NCBI
RefSeq Acc Id: NP_113951   ⟸   NM_031763
- UniProtKB: P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   P63004 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075779   ⟸   ENSRNOT00000092712
Ensembl Acc Id: ENSRNOP00000003696   ⟸   ENSRNOT00000003696
RefSeq Acc Id: XP_038942872   ⟸   XM_039086944
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126034   ⟸   XM_063269964
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126033   ⟸   XM_063269963
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126037   ⟸   XM_063269967
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126035   ⟸   XM_063269965
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126038   ⟸   XM_063269968
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126036   ⟸   XM_063269966
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126039   ⟸   XM_063269969
- Peptide Label: isoform X1
- UniProtKB: P63004 (UniProtKB/Swiss-Prot),   Q9R2A6 (UniProtKB/Swiss-Prot),   P81692 (UniProtKB/Swiss-Prot),   P43035 (UniProtKB/Swiss-Prot),   O35592 (UniProtKB/Swiss-Prot),   A6HGN1 (UniProtKB/TrEMBL)
Protein Domains
LisH   PAC1-like LisH-like dimerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63004-F1-model_v2 AlphaFold P63004 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697414
Promoter ID:EPDNEW_R7936
Type:multiple initiation site
Name:Pafah1b1_2
Description:platelet-activating factor acetylhydrolase 1b, regulatory subunit1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7937  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01061,576,932 - 61,576,992EPDNEW
RGD ID:13697413
Promoter ID:EPDNEW_R7937
Type:initiation region
Name:Pafah1b1_1
Description:platelet-activating factor acetylhydrolase 1b, regulatory subunit1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7936  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01061,577,444 - 61,577,504EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620331 AgrOrtholog
BioCyc Gene G2FUF-24257 BioCyc
Ensembl Genes ENSRNOG00000002755 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003696 ENTREZGENE
  ENSRNOT00000003696.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.960.30 UniProtKB/Swiss-Prot
  2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7104733 IMAGE-MGC_LOAD
InterPro Dynein_regulator_LIS1 UniProtKB/Swiss-Prot
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  LIS1_N UniProtKB/Swiss-Prot
  LisH UniProtKB/Swiss-Prot
  PAC1-like_LisH-like_dom UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
  WD_LIS1/nudF_dynein_reg UniProtKB/Swiss-Prot
KEGG Report rno:83572 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91446 IMAGE-MGC_LOAD
NCBI Gene 83572 ENTREZGENE
PANTHER WD REPEAT-CONTAINING PROTEIN POP1 UniProtKB/Swiss-Prot
Pfam LisH_PAC1 UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Pafah1b1 PhenoGen
PIRSF Dynein_regulator_Lis1 UniProtKB/Swiss-Prot
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE LISH UniProtKB/Swiss-Prot
  WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002755 RatGTEx
SMART LisH UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109925 UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot
UniProt A6HGN1 ENTREZGENE, UniProtKB/TrEMBL
  A6HGN2_RAT UniProtKB/TrEMBL
  LIS1_RAT UniProtKB/Swiss-Prot
  O35592 ENTREZGENE
  P43035 ENTREZGENE
  P63004 ENTREZGENE
  P81692 ENTREZGENE
  Q9R2A6 ENTREZGENE
UniProt Secondary O35592 UniProtKB/Swiss-Prot
  P43035 UniProtKB/Swiss-Prot
  P81692 UniProtKB/Swiss-Prot
  Q9R2A6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-06 Pafah1b1  platelet-activating factor acetylhydrolase 1b, regulatory subunit 1  Pafah1b1  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-04-21 Pafah1b1  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1  Pafah1b1  platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Pafah1b1  platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa    platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)  Name updated 1299863 APPROVED
2002-08-07 Pafah1b1  platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)      Symbol and Name status set to provisional 70820 PROVISIONAL