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Gene: Furin (furin (paired basic amino acid cleaving enzyme)) Rattus norvegicus

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Symbol:

Furin

Name:

furin (paired basic amino acid cleaving enzyme)

RGD ID:

3274

Description:

Enables serine-type endopeptidase activity. Involved in positive regulation of cell migration; positive regulation of transforming growth factor beta receptor signaling pathway; and protein processing. Located in Golgi cisterna and endoplasmic reticulum membrane. Orthologous to human FURIN (furin, paired basic amino acid cleaving enzyme); PARTICIPATES IN glypican signaling pathway; hypoxia inducible factor pathway; Notch signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dibasic-processing enzyme; LOC360309; Pace; Paired basic amino acid cleaving enzyme (furin); paired basic amino acid residue cleaving enzyme; paired basic amino acid residue-cleaving enzyme; Pcsk3; prohormone convertase 3; Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme furin membrane associated receptor protein); Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein); proprotein convertase subtilisin/kexin type3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FURIN (furin, paired basic amino acid cleaving enzyme)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Furin (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Furin (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FURIN (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FURIN (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Furin (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FURIN (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FURIN (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Furin (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Furin (furin, paired basic amino acid cleaving enzyme)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CYGB (cytoglobin)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Furin (furin, paired basic amino acid cleaving enzyme)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FURIN (furin, paired basic amino acid cleaving enzyme)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	furinb (furin (paired basic amino acid cleaving enzyme) b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	furina (furin (paired basic amino acid cleaving enzyme) a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	KEX2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	KEX2	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Fur1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	kpc-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	kpc-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	furin	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	furin	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	143,757,389 - 143,770,430 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	143,757,391 - 143,773,497 (-)	Ensembl				GRCr8
mRatBN7.2	1	134,348,142 - 134,361,182 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,348,144 - 134,364,314 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	142,257,013 - 142,269,107 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,426,407 - 149,438,502 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,344,416 - 142,356,506 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	142,185,092 - 142,198,167 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	142,185,094 - 142,197,182 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	143,137,721 - 143,153,628 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	136,209,969 - 136,222,057 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	126,407,744 - 126,419,832 (-)	NCBI		Celera
RGSC_v3.1	1	136,288,374 - 136,300,463	NCBI
RH 3.4 Map	1	1074.0	RGD
Cytogenetic Map	1	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

arteriosclerosis (ISO)

carcinoma (ISO)

coronary artery disease (ISO)

Experimental Diabetes Mellitus (IEP)

Experimental Mammary Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

2-amino-2-deoxy-D-glucopyranose (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

acetylsalicylic acid (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucosamine (ISO)

amitrole (EXP)

ammonium chloride (EXP)

apomorphine (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenic trichloride (ISO)

batimastat (ISO)

benzo[a]pyrene (ISO)

beta-D-glucosamine (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP)

calcium atom (EXP)

calcium(0) (EXP)

cannabidiol (ISO)

carbon nanotube (ISO)

CGS 15943 (ISO)

chlorpyrifos (ISO)

chromium atom (ISO)

cisplatin (ISO)

cobalt dichloride (EXP,ISO)

copper(II) chloride (ISO)

cordycepin (ISO)

cyclosporin A (ISO)

DDE (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diminazene diaceturate (ISO)

drometrizole (ISO)

ethanol (ISO)

fenthion (ISO)

flavonoids (EXP)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

kenpaullone (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methidathion (ISO)

methimazole (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodimethylamine (ISO)

naled (ISO)

nickel dichloride (ISO)

paclitaxel (ISO)

paracetamol (EXP,ISO)

PhIP (EXP)

potassium dichromate (ISO)

rac-lactic acid (ISO)

Rutecarpine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium chloride (EXP)

sodium dichromate (ISO)

Soman (EXP)

sulfadimethoxine (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst formation (IEA,ISO)

cholesterol homeostasis (ISO)

cytokine precursor processing (IEA,ISO,ISS)

dibasic protein processing (IEA,ISO)

negative regulation of low-density lipoprotein particle receptor catabolic process (IEA,ISO)

negative regulation of nerve growth factor production (ISO)

negative regulation of transforming growth factor beta1 production (IEA,ISO)

nerve growth factor production (IEA,ISO)

peptide biosynthetic process (IEA,ISO)

peptide hormone processing (IBA,IEA,ISO)

positive regulation of cell migration (IMP)

positive regulation of transforming growth factor beta receptor signaling pathway (IMP)

positive regulation of viral entry into host cell (IEA)

protein maturation (IEA,ISO)

protein processing (IDA,IEA,IMP,ISO)

proteolysis (IEA)

regulation of cholesterol transport (ISO)

regulation of protein catabolic process (IEA,ISO)

regulation of signal transduction (ISO)

secretion by cell (IEA,ISO)

signal peptide processing (IBA,IEA,ISO)

viral life cycle (IEA,ISO)

zymogen activation (IEA,ISO)

zymogen inhibition (ISO)

Cellular Component

cell surface (IEA,ISO)

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IDA)

endosome membrane (IEA)

extracellular region (IEA)

extracellular space (ISO)

Golgi apparatus (IEA,ISO)

Golgi cisterna (IDA)

Golgi lumen (IEA,ISO)

Golgi membrane (IBA,IEA,ISO)

membrane raft (IEA,ISO)

organelle membrane (IEA)

plasma membrane (IEA)

trans-Golgi network (IBA,IEA,ISO)

trans-Golgi network transport vesicle (IEA,ISO)

Molecular Function

endopeptidase activator activity (IEA,ISO)

endopeptidase activity (IEA,ISO)

endopeptidase inhibitor activity (IEA,ISO)

heparan sulfate binding (IEA,ISO,ISS)

heparin binding (IEA,ISO,ISS)

hydrolase activity (IEA)

metal ion binding (IEA)

nerve growth factor binding (IEA,ISO)

peptidase activity (IEA,ISO)

peptide binding (IEA,ISO)

protease binding (IEA,ISO)

protein binding (ISO)

serine-type endopeptidase activity (IBA,IEA,IMP,ISO,ISS)

serine-type endopeptidase inhibitor activity (IEA,ISO)

serine-type peptidase activity (IEA,ISO)

signal peptidase activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glypican signaling pathway (ISO)

hypoxia inducible factor pathway (ISO)

influenza A pathway (IEA)

Notch signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Expression and localization of MT1-MMP and furin in the glomerular wall of short- and long-term diabetic rats.	Boucher E, etal., Kidney Int. 2006 May;69(9):1570-7.
2.	Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.	Bowler RP, etal., J Biol Chem 2002 May 10;277(19):16505-11.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6.	Gene-gene interactions among genetic variants from obesity candidate genes for nonobese and obese populations in type 2 diabetes.	Lin E, etal., Genet Test Mol Biomarkers. 2009 Aug;13(4):485-93.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Sequence of the cDNA encoding rat furin, a possible propeptide-processing endoprotease.	Misumi Y, etal., Nucleic Acids Res 1990 Nov 25;18(22):6719.
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	GOA pipeline	RGD automated data pipeline
12.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
14.	Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta1 involves furin-convertase.	Stawowy P, etal., Cardiovasc Res. 2004 Jul 1;63(1):87-97.
15.	Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosis.	Stawowy P, etal., Virchows Arch. 2005 Apr;446(4):351-9. Epub 2005 Mar 9.
16.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:7737999	PMID:8262946	PMID:8615794	PMID:8940009	PMID:9130696	PMID:9242664	PMID:9695949	PMID:10526337	PMID:10567353	PMID:11799113	PMID:12447384	PMID:12665557
PMID:14744861	PMID:15078902	PMID:15082773	PMID:15146101	PMID:15358140	PMID:15606899	PMID:15899807	PMID:16239403	PMID:16537537	PMID:16912035	PMID:17010968	PMID:17936261
PMID:17938254	PMID:19199708	PMID:19946888	PMID:20076849	PMID:20375258	PMID:20489134	PMID:20530870	PMID:21147780	PMID:21763278	PMID:23418414	PMID:23686857	PMID:23918928
PMID:26416966	PMID:31336100	PMID:36063111

Genomics

Comparative Map Data

Furin
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	143,757,389 - 143,770,430 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	143,757,391 - 143,773,497 (-)	Ensembl				GRCr8
mRatBN7.2	1	134,348,142 - 134,361,182 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,348,144 - 134,364,314 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	142,257,013 - 142,269,107 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,426,407 - 149,438,502 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,344,416 - 142,356,506 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	142,185,092 - 142,198,167 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	142,185,094 - 142,197,182 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	143,137,721 - 143,153,628 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	136,209,969 - 136,222,057 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	126,407,744 - 126,419,832 (-)	NCBI		Celera
RGSC_v3.1	1	136,288,374 - 136,300,463	NCBI
RH 3.4 Map	1	1074.0	RGD
Cytogenetic Map	1	q31	NCBI

FURIN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	90,868,588 - 90,883,457 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	90,868,588 - 90,883,564 (+)	Ensembl			hg38	GRCh38
GRCh37	15	91,411,818 - 91,426,687 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	89,212,889 - 89,227,691 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	89,212,888 - 89,227,691	NCBI
Celera	15	67,820,515 - 67,835,658 (+)	NCBI		Celera
Cytogenetic Map	15	q26.1	NCBI
HuRef	15	67,523,022 - 67,538,192 (+)	NCBI		HuRef
CHM1_1	15	91,253,454 - 91,268,261 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	88,627,830 - 88,643,054 (+)	NCBI		T2T-CHM13v2.0

Furin
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	80,038,942 - 80,055,188 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	80,038,333 - 80,055,184 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	80,389,194 - 80,405,441 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	80,388,585 - 80,405,436 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	87,534,080 - 87,550,317 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	80,262,709 - 80,276,275 (-)	NCBI		MGSCv36	mm8
Celera	7	77,789,167 - 77,805,351 (-)	NCBI		Celera
Cytogenetic Map	7	D2	NCBI
cM Map	7	45.65	NCBI

Furin
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	14,936,546 - 14,949,252 (+)	Ensembl
ChiLan1.0	NW_004955416	14,915,031 - 14,947,634 (+)	NCBI	ChiLan1.0	ChiLan1.0

FURIN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	80,423,872 - 80,436,846 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	84,121,785 - 84,134,845 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	69,560,774 - 69,576,007 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	88,759,729 - 88,774,023 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	88,763,269 - 88,774,023 (+)	Ensembl			panPan2	panpan1.1

FURIN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	53,357,491 - 53,368,285 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	53,358,045 - 53,365,423 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	55,995,115 - 56,006,746 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	53,773,528 - 53,785,153 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	53,773,530 - 53,785,145 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	53,292,643 - 53,304,269 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	53,503,862 - 53,515,505 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	53,844,352 - 53,855,974 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Furin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	130,182,463 - 130,198,421 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	16,136,099 - 16,144,635 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	16,136,099 - 16,147,945 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FURIN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	53,460,017 - 53,472,787 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	53,455,634 - 53,472,791 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	58,486,815 - 58,503,979 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FURIN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	8,980,367 - 8,992,257 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	8,979,720 - 8,988,235 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	37,732,423 - 37,745,148 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Furin
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	17,371,628 - 17,387,881 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624768	17,372,754 - 17,387,732 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Furin
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	119,842,424 - 119,855,895 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Furin
151 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	471
Count of miRNA genes:	249
Interacting mature miRNAs:	306
Transcripts:	ENSRNOT00000015521
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
631684	Bp117	Blood pressure QTL 117	8.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	120082258	165082258	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	112521556	157521556	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
631570	Bp94	Blood pressure QTL 94		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132889797	152403053	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	142582180	153680016	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	124975316	152612788	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	141173126	169168317	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	108680016	153680016	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	112521556	157521556	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	111949780	160574007	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	152404087	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat

Markers in Region

D1Smu12

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,357,949 - 134,358,075 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,194,900 - 142,195,025	NCBI	Rnor6.0
Rnor_5.0	1	143,147,913 - 143,148,038	UniSTS	Rnor5.0
Celera	1	126,417,550 - 126,417,675	UniSTS
Cytogenetic Map	1	q31	UniSTS

D1Bda27

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,348,264 - 134,348,555 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,185,215 - 142,185,505	NCBI	Rnor6.0
Rnor_5.0	1	143,137,844 - 143,138,134	UniSTS	Rnor5.0
RGSC_v3.4	1	136,210,090 - 136,210,380	UniSTS	RGSC3.4
Celera	1	126,407,865 - 126,408,155	UniSTS
Cytogenetic Map	1	q31	UniSTS

PMC156147P3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,355,760 - 134,356,479 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,192,711 - 142,193,429	NCBI	Rnor6.0
Rnor_5.0	1	143,145,340 - 143,146,442	UniSTS	Rnor5.0
Rnor_5.0	1	143,145,340 - 143,146,058	UniSTS	Rnor5.0
RGSC_v3.4	1	136,217,586 - 136,218,304	UniSTS	RGSC3.4
Celera	1	126,415,361 - 126,416,079	UniSTS
Cytogenetic Map	1	q31	UniSTS

RH94589

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,348,147 - 134,348,343 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,185,098 - 142,185,293	NCBI	Rnor6.0
Rnor_5.0	1	143,137,727 - 143,137,922	UniSTS	Rnor5.0
RGSC_v3.4	1	136,209,973 - 136,210,168	UniSTS	RGSC3.4
Celera	1	126,407,748 - 126,407,943	UniSTS
RH 3.4 Map	1	1074.0	UniSTS
Cytogenetic Map	1	q31	UniSTS

Pcsk3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,355,488 - 134,356,700 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,192,439 - 142,193,650	NCBI	Rnor6.0
Rnor_5.0	1	143,145,068 - 143,146,663	UniSTS	Rnor5.0
RGSC_v3.4	1	136,217,314 - 136,218,525	UniSTS	RGSC3.4
Celera	1	126,415,089 - 126,416,300	UniSTS
Cytogenetic Map	1	q31	UniSTS

FURIN

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,357,114 - 134,357,271 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,194,065 - 142,194,221	NCBI	Rnor6.0
Rnor_5.0	1	143,147,078 - 143,147,234	UniSTS	Rnor5.0
RGSC_v3.4	1	136,218,940 - 136,219,096	UniSTS	RGSC3.4
Celera	1	126,416,715 - 126,416,871	UniSTS
Cytogenetic Map	1	q31	UniSTS

FURIN

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	143,763,446 - 143,764,013 (+)	Marker Load Pipeline
mRatBN7.2	1	134,354,199 - 134,354,764 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,191,150 - 142,191,714	NCBI	Rnor6.0
Rnor_5.0	1	143,143,779 - 143,144,343	UniSTS	Rnor5.0
RGSC_v3.4	1	136,216,025 - 136,216,589	UniSTS	RGSC3.4
Celera	1	126,413,800 - 126,414,364	UniSTS
Cytogenetic Map	1	q31	UniSTS

Furin

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	134,350,129 - 134,351,453 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	142,187,080 - 142,188,403	NCBI	Rnor6.0
Rnor_5.0	1	143,139,709 - 143,141,032	UniSTS	Rnor5.0
Celera	1	126,409,730 - 126,411,053	UniSTS
Cytogenetic Map	1	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001440086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_019331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X55660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015521 ⟹ ENSRNOP00000015521

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	143,757,391 - 143,769,481 (-)	Ensembl
mRatBN7.2 Ensembl	1	134,348,144 - 134,360,188 (-)	Ensembl
Rnor_6.0 Ensembl	1	142,185,094 - 142,197,182 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102738 ⟹ ENSRNOP00000088681

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	143,757,391 - 143,773,497 (-)	Ensembl
mRatBN7.2 Ensembl	1	134,348,144 - 134,364,314 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116325 ⟹ ENSRNOP00000088247

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	143,757,391 - 143,769,598 (-)	Ensembl
mRatBN7.2 Ensembl	1	134,348,144 - 134,361,046 (-)	Ensembl

RefSeq Acc Id:

NM_019331 ⟹ NP_062204

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,757,391 - 143,769,481 (-)	NCBI
mRatBN7.2	1	134,348,144 - 134,360,232 (-)	NCBI
Rnor_6.0	1	142,185,094 - 142,197,182 (-)	NCBI
Rnor_5.0	1	143,137,721 - 143,153,628 (-)	NCBI
RGSC_v3.4	1	136,209,969 - 136,222,057 (-)	RGD
Celera	1	126,407,744 - 126,419,832 (-)	RGD

Sequence:

show sequence

AAAAAAGAGGATTCCGTGGCTTAAAAAAAAAGTTTGAAAGCCTCTGACTTAATAGTTTCCACCA
CCAAGGAAACTGAGGCCCAGAGAGAGGAAATGACCTGGGTAAGATCTCCGAGGGACCAGTAGTT
GAACAGGGACTAGGAGTTAAAATTTCATGGGAGGTGCCTGTAACAGGACCTGCCTTGGGGTCTC
TGCTGGAAAGAGAGACCTGATTGGGTTTCCCAGCAGTCTTCAGTGGCTTGCTCCGTGGCTGCCT
CAGCCAGGTCTCCAGCAGCCACACCTGGGGATCTGGCCCCCGTCCTGTCCTCCAGCCCCACCCA
CCTCGGCTCCATGCCCCCCCCAGTCAGCTTCGGGACCCTGGCAGTGAGCAGGCACGTGGCAGCC
AAGGCCCTGTGACCAGGCCAGGGAGACGGAGCTCTGGGGTCCCAGTCACCTGCCCCCCCATGGA
GCTGAGACCCTGGTTGCTATGGGTGGTAGCAGCAGCAGGAGCCTTGGTCCTGCTAGCAGCTGAA
GCTCGCGGCCAGAAGATCTTCACCAACACGTGGGCTGTGCACATTTCTGGAGGCCCAGCTGTGG
CTGATAGTGTGGCACGGAAGCATGGGTTCCACAACCTGGGCCAGATCTTCGGTGACTATTACCA
CTTCTGGCACAGAGCAGTGACAAAGCGGTCCCTGTCGCCTCACCGCCCGCGGCACAGCCGGCTA
CAGAGGGTGCCTCAAGTGAAGTGGCTGGAGCAGCAGGTAGCCAAGCAAAGGGCCAAGAGGGACG
TGTATCAGGAGCCCACAGACCCCAAGTTCCCTCAGCAGTGGTACCTGTCTGGGGTCACTCAGCG
AGACCTGAATGTGAAGGAAGCCTGGGCCCAGGGCTTCACAGGGCGTGGCATTGTGGTCTCCATC
CTGGATGACGGCATTGAAAAGAACCATCCTGACTTGGCAGGCAATTATGACCCGGGAGCCAGCT
TTGATGTCAATGACCAGGACCCTGACCCACAGCCTCGGTACACGCAGATGAATGACAACAGGCA
CGGCACTCGGTGTGCCGGGGAAGTGGCAGCGGTGGCCAACAATGGTGTCTGTGGTGTAGGTGTA
GCTTACAATGCCCGGATTGGAGGGGTGCGTATGTTGGATGGCGAGGTGACTGACGCGGTAGAGG
CACGTTCGCTGGGCCTGAATCCCAACCACATCCACATCTACAGCGCCAGCTGGGGCCCCGAGGA
CGACGGCAAGACCGTGGATGGGCCAGCCCGGCTCGCCGAGGAGGCCTTCTTTCGGGGAGTTAGC
CAGGGCCGCGGAGGGCTGGGCTCCATCTTTGTCTGGGCCTCAGGGAATGGGGGCCGGGAACATG
ACAGCTGTAACTGTGACGGCTACACCAACAGTATCTACACGCTGTCCATCAGCAGTGCCACACA
ATTCGGCAACGTGCCCTGGTACAGTGAGGCCTGCTCCTCCACACTGGCCACCACCTACAGCAGT
GGCAACCAGAATGAGAAGCAGATTGTGACAACTGACTTGAGGCAGAAGTGCACTGAGTCTCACA
CAGGCACCTCAGCCTCCGCCCCTTTGGCAGCTGGTATCATTGCTCTCACCCTGGAGGCCAACAA
GAACCTCACCTGGCGGGACATGCAGCACCTGGTGGTGCAGACCTCAAAGCCAGCACATCTCAAC
GCTAACGATTGGGCCACCAATGGCGTGGGCCGGAAAGTGAGCCATTCCTATGGCTACGGGCTGT
TGGATGCAGGTGCCATGGTGGCCCTGGCCCAGAACTGGACAACAGTGGCCCCCCAGCGGAAGTG
CATCATTGAAATCCTGGCAGAGCCCAAGGACATTGGCAAACGGCTAGAGGTGCGCAAGACCGTG
ACAGCGTGCCTGGGTGAGCCCAACCACATCTCCAGACTGGAACACGTTCAGGCACGGCTCACCC
TGTCTTACAATCGCCGTGGTGACCTGGCTATCCACCTCATCAGCCCCATGGGCACCCGTTCCAC
CCTATTAGCTGCCAGACCACATGACTACTCTGCTGATGGATTTAATGACTGGGCTTTCATGACA
ACTCATTCCTGGGATGAGGACCCCTCTGGCGAGTGGGTCCTAGAGATTGAAAATACCAGCGAGG
CCAACAACTATGGGACGCTGACCAAGTTCACTCTCGTCCTATATGGCACAGCCTCTGAGGGTCT
CTCTGCACCTCCAGAGAGCAGCGGCTGCAAGACCCTCACATCCAGCCAGGCCTGCGTGGTGTGT
GAGGAAGGTTTCTCACTGCACCAGAAAAGCTGTGTCCAGCGTTGCCCACCAGGCTTCACACCCC
AAGTCCTTGATACACACTACAGCACTGAGAATGATGTGGAGATCATCCGTGCCAGCGTCTGCAC
CCCCTGCCACGCCTCATGTGCCACTTGCCAGGGCCCAGCTCCCACAGACTGCCTCAGCTGCCCC
AGCCATGCCTCCCTGGACCCTGTGGAGCAAACCTGCTCCCGGCAAAGCCAGAGCAGCCGAGAGT
CCCGACCTCAGCAGCCACCTCCCGCACTGCGCCCAGAGGTGGAAGTGGAGCCCCGGTTGCGGGC
TGGGCTGGCCTCTCACCTGCCGGAGGTCCTGGCCGGCCTCAGCTGCCTTATCATCGCTCTCATC
TTTGGCATCGTCTTCCTCTTCCTGCATCGGTGTTCAGGCTTCAGCTTCCGGGGAGTGAAAGTGT
ACACCATGGACCGTGGCCTCATCTCCTACAAGGGGCTGCCTCCTGAGGCCTGGCAGGAGGAGTG
CCCATCTGACTCAGAAGAGGATGAGGGCCGGGGCGAGAGGACCGCCTTTATCAAAGACCAGAGC
GCCCTTTGATGAGCCCACTGCCCACCCTATCAAATCGATCCCTTCCTCGGCACTTTTTAATTCA
CCAAAGTATTTTTTTATCTTGGGACTGGGTTTGGACCCTAGCTGGGAGGTGAGAGGGGCAGAGA
CCCTTGGGCCTACCTGTTTGCCTGAGGTGGGGTCCCGGGAGCCTCACCCCCCACCAACCCTCCA
TGTGGAGGAAGGAGTAAATCTTTAGGGCAGCTTCCTGCAGAGTGAAGAGGGGCAGCCTTTCTGA
CTCCCTGGCCAGCTGCAGCCTTGCCCCTCCCCTGCCCCTCAGAAAGCAATAATGGTCCCCATCC
AGGCAACAGGGAGGCTGGCCAGGAGGTACTTGAAGAAGGTGGCCACCTCTCCAAGGGCTTTTGC
ATCCCCTGACCCTCTCTGGCTCAGGATGAGCCTCTGAAGAAGCTTGCAGTCACAGGAAGGGACC
AAAGCAAACGAGGCACTCTCCAGTGTGCCTGCACTCTTGCTCTCAGCCTGCCTCTGCACTCCAG
GTCTCCACCTCAGCTGGTAGCCAGGCTGAGCTAGACCTGCACAGGTCAGGCTCTGGGGCCTTAT
GCTGGTGTCCTGACCATCCTCTATGGCACCCCCCCCCCAAGCCAGGGCCTTGTTTTCTGAGCCC
GGGGCTGCCTGGGCAGTTGGCGCTCACAGTCCAGGAGCCCCTGGGTGGGTGGTGGGGAGGGACG
GTGGCTCCTCCCACCTCCCACCCGATGCTGCTTTCCCCTGTGGGGATCTCAGGAGCTGTTTGAG
GATATATTTTCACTTTGTGATTATTCACTTTAGATGCTGATTTTTTTTTTTTTGTATTTTTAAT
GGGGGTAGCAGCTGGACCATTCACCTTCTCCTACCCATGTCCACCCTGCCTTTCCCATGGCTGC
CCAGCTCTGAGGCAGAGGGAATCACTAAGCCCCAAGTCCTGAAGAGGCAGGCCAGCCAGCTGGG
CTCCAGGAAAGGGGGTCATGGTGGGAGGGGTAGGCTGACATCATCTGTTTCAAATGGGGTTGTG
CCACAGGCTTTTGGGTTGCTGGCTCTCCAAGTGCCAGGGGTGGGCAGGTGGCACCACCAAGCCC
AAACTAACACTGTGCCCTGGTGGAGAAAGCATTGGCCTATGATGCCCCCCAAACCCCCTGTTCT
GATGTGCCTTTCGCACCCCTCCCATTAGGACAATCAGTCCCCTCCCACTTGGGCCTCCTCTTTT
CTTTTTCCTAGCCCTTCTCGGTACCCAACCTACCTGTCCAGGGTGCCCCTTGCTCTCCTGCCCA
CCCCTAGCGGCCATCCAGGCTGGTTTTGTAAGATGCTGGGTTGGTGCACAGTCATTTTTTTTTC
CTTGTAATTTAAACAGGCCTGGCATTGTTGGTTCTATTTAATGGACACGAGATAATGTTAGAGG
TTTTAAAGTGATTAAACGTGCAGACTATGCAAACC

hide sequence

RefSeq Acc Id:

XM_008759555 ⟹ XP_008757777

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,757,389 - 143,770,430 (-)	NCBI
mRatBN7.2	1	134,348,142 - 134,361,182 (-)	NCBI
Rnor_6.0	1	142,185,092 - 142,198,167 (-)	NCBI

Sequence:

show sequence

GCCGGGCCGAGGCCGCGCCGCCGCGCCTCCCCGCCTGCGCGCTGTGACGCCGCTGCCGGGCGCG
GGGACCGCCCGAGCCAGGCCCCCGCCGCCGGGCTCCGTGCTCGGCCGAGGGGTACCCGAGCAGC
CGCGGCGCTCGTCCGGAAAAGTTTCCCCGCCCGGCTCCCCAGGATCTGGCCCCCGTCCTGTCCT
CCAGCCCCACCCACCTCGGCTCCATGCCCCCCCCAGTCAGCTTCGGGACCCTGGCAGTGAGCAG
GCACGTGGCAGCCAAGGCCCTGTGACCAGGCCAGGGAGACGGAGCTCTGGGGTCCCAGTCACCT
GCCCCCCCATGGAGCTGAGACCCTGGTTGCTATGGGTGGTAGCAGCAGCAGGAGCCTTGGTCCT
GCTAGCAGCTGAAGCTCGCGGCCAGAAGATCTTCACCAACACGTGGGCTGTGCACATTTCTGGA
GGCCCAGCTGTGGCTGATAGTGTGGCACGGAAGCATGGGTTCCACAACCTGGGCCAGATCTTCG
GTGACTATTACCACTTCTGGCACAGAGCAGTGACAAAGCGGTCCCTGTCGCCTCACCGCCCGCG
GCACAGCCGGCTACAGAGGGAGCCTCAAGTGAAGTGGCTGGAGCAGCAGGTAGCCAAGCAAAGG
GCCAAGAGGGACGTGTATCAGGAGCCCACAGACCCCAAGTTCCCTCAGCAGTGGTACCTGTCTG
GGGTCACTCAGCGAGACCTGAATGTGAAGGAAGCCTGGGCCCAGGGCTTCACAGGGCGTGGCAT
TGTGGTCTCCATCCTGGATGACGGCATTGAAAAGAACCATCCTGACTTGGCAGGCAATTATGAC
CCGGGAGCCAGCTTTGATGTCAATGACCAGGACCCTGACCCACAGCCTCGGTACACGCAGATGA
ATGACAACAGGCACGGCACTCGGTGTGCCGGGGAAGTGGCAGCGGTGGCCAACAATGGTGTCTG
TGGTGTAGGTGTAGCTTACAATGCCCGGATTGGAGGGGTGCGTATGTTGGATGGCGAGGTGACT
GACGCGGTAGAGGCACGTTCGCTGGGCCTGAATCCCAACCACATCCACATCTACAGCGCCAGCT
GGGGCCCCGAGGACGACGGCAAGACCGTGGATGGGCCAGCCCGGCTCGCCGAGGAGGCCTTCTT
TCGGGGAGTTAGCCAGGGCCGCGGAGGGCTGGGCTCCATCTTTGTCTGGGCCTCAGGGAACGGG
GGCCGGGAACATGACAGCTGTAACTGTGACGGCTACACCAACAGCATCTACACGCTGTCCATCA
GCAGTGCCACACAATTCGGCAACGTGCCCTGGTACAGTGAGGCCTGCTCCTCCACACTGGCCAC
CACCTACAGCAGTGGCAACCAGAATGAGAAGCAGATTGTGACAACTGACCTGAGGCAGAAGTGC
ACTGAGTCTCACACAGGCACCTCAGCCTCCGCCCCTTTGGCAGCTGGTATCATTGCTCTCACCC
TGGAGGCCAACAAGAACCTCACCTGGCGGGACATGCAGCACCTGGTGGTGCAGACCTCAAAGCC
AGCACATCTCAACGCTAACGATTGGGCCACCAATGGCGTGGGCCGGAAAGTGAGCCATTCCTAT
GGCTACGGGCTGTTGGATGCAGGTGCCATGGTGGCCCTGGCCCAGAACTGGACAACAGTGGCCC
CCCAGCGGAAGTGCATCATTGAAATCCTGGCAGAGCCCAAGGACATTGGCAAACGGCTAGAGGT
GCGCAAGACCGTGACAGCGTGCCTGGGTGAGCCCAACCACATCTCCAGACTGGAACACGTTCAG
GCACGGCTCACCCTGTCTTACAATCGCCGTGGTGACCTGGCTATCCACCTCATCAGCCCCATGG
GCACCCGTTCCACCCTATTAGCTGCCAGACCACATGACTACTCTGCTGATGGATTTAATGACTG
GGCTTTCATGACAACTCATTCCTGGGATGAGGACCCCTCTGGCGAGTGGGTCCTAGAGATTGAA
AATACCAGCGAGGCCAACAACTATGGGACGCTGACCAAGTTCACTCTCGTCCTATATGGCACAG
CCTCTGAGGGTCTCTCTGCACCTCCAGAGAGCAGCGGCTGCAAGACCCTCACATCCAGCCAGGC
CTGCGTGGTGTGTGAGGAAGGTTTCTCACTGCACCAGAAAAGCTGTGTCCAGCGTTGCCCACCA
GGCTTCACACCCCAAGTCCTTGATACACACTACAGCACTGAGAATGATGTGGAGATCATCCGTG
CCAGTGTCTGCACCCCCTGCCACGCCTCATGTGCCACTTGCCAGGGCCCAGCTCCCACAGACTG
CCTCAGCTGCCCCAGCCATGCCTCCCTGGACCCTGTGGAGCAAACCTGCTCCCGGCAAAGCCAG
AGCAGCCGAGAGTCCCGACCTCAGCAGCCACCTCCCGCACTGCGCCCAGAGGTGGAAGTGGAGC
CCCGGTTGCGGGCTGGGCTGGCCTCTCACCTGCCGGAGGTCCTGGCCGGCCTCAGCTGCCTTAT
CATCGCTCTCATCTTTGGCATCGTCTTCCTCTTCCTGCATCGGTGTTCAGGCTTCAGCTTCCGG
GGAGTGAAAGTGTACACCATGGACCGTGGCCTCATCTCCTACAAGGGGCTGCCTCCTGAGGCCT
GGCAGGAGGAGTGCCCATCTGACTCAGAAGAGGATGAGGGCCGGGGCGAGAGGACCGCCTTTAT
CAAAGACCAGAGCGCCCTTTGATGAGCCCACTGCCCACCCTATCAAATCGATCCCTTCCTCGGG
CACTTTTTAATTCACCAAAGTATTTTTTTATCTTGGGACTGGGTTTGGACCCTAGCTGGGAGGT
GAGAGGGGCAGAGACCCTTGGGCCTACCTGTTTGCCTGAGGTGGGGTCCCGGGAGCCTCACCCC
CCACCAACCCTCCATGTGGAGGAAGGAGTAAATCTTTAGGGCAGCTTCCTGCAGAGTGAAGAGG
GGCAGCCTTTCTGAGTCCCTGGCCAGGCTGCAGCCTTGCCCCTCCCCTGCCCCTCAGAAAGCAA
TAATGGTCCCCATCCAGGCAACAGGGAGGCTGGCCAGGAGGTACTTGAAGAAGGTGGCCACCTC
TCCAAGGGCTTTTGCATCCCCTGACCCTCTCTGGCTCAGGATGAGCCTCTGAAGAAGCTTGCAG
TCACAGGAAGGGACCAAAGCAAAGCAGGCACTCTCCAGTGTGCCTGCACTCTTGCTCTCAGCCT
GCCTCTGCACTCCAGGTCTCCACCTCAGCTGGTAGCCAGGCTGAGCTAGACCAGCACAGGTCAG
GCTCTGGGGCCTTATGCTGGTGTCCTGACCATCCTCTATGGCACCCTCCCCCTTGCCAGGGCCT
TGTTTTCTGAGCCCGGGGCTGCCTGGGCAGTTGGCGCTCACAGTCCAGGAGCCCCTGGGTGGGT
GGTGGGGAGGGACGGTGGCTCCTCCCGCCTCCCACCCGATGCTGCTTTCCCCTGTGGGGATCTC
AGGAGCTGTTTGAGGATATATTTTCACTTTGTGATTATTCACTTTAGATGCTGATTTTTTTTTT
TTTTTGTATTTTTAATGGGGGTAGCAGCTGGACCATTCACCTTCTCCTACCCATGTCCACCCTG
CCTTTCCCATGGCTGCCCAGCTCTGAGGCAGAGGGAATCACTAAGCCCCAAGTCCTGAAGAGGC
AGGCCAGCCAGCTGGGCTCCAGGAAAGGGGGTCATGGTGGGAGGGGTAGGCTGACATCATCTGT
TTCAAATGGGGTTGTGCCACAGGCTTTTGGGTTGCTGGCTCTCCAAGTGCCAGGGGTGGGCAGG
TGGCACCACCAAGCCCTTTCTAACACTGTGCCCTGGTGGAGAAAGCATTGGCCTATGATGCCCC
CCAAACCCCCTGTTCTGATGTGCCTTTCGCACCCCTCCCATTAGGACAATCAGTCCCCTCCCAC
TTGGGCCTCCTCTTTTCTTTTTCCTAGCCCTTCTCGGTACCCAACCTACCTGTCCAGGGGTGCC
CCTTGCTCTCCTGCCCACCCCTAGCGGCCATCCAGGCTGGTTTTGTAAGATGCTGGGTTGGTGC
ACAGTCATTTTTTTTTCCTTGTAATTTAAACAGGCCTGGCATTGTTGGTTCTATTTAATGGACA
CGAGATAATGTTAGAGGTTTTAAAGTGATTAAACGTGCAGACTATGCAAACCAA

hide sequence

RefSeq Acc Id:

XM_063271946 ⟹ XP_063128016

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,757,389 - 143,769,531 (-)	NCBI

RefSeq Acc Id:

XM_063271951 ⟹ XP_063128021

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,757,389 - 143,769,798 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001427015	(Get FASTA)	NCBI Sequence Viewer
	NP_062204	(Get FASTA)	NCBI Sequence Viewer
	XP_008757777	(Get FASTA)	NCBI Sequence Viewer
	XP_063128016	(Get FASTA)	NCBI Sequence Viewer
	XP_063128021	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA39193	(Get FASTA)	NCBI Sequence Viewer
	EDM08645	(Get FASTA)	NCBI Sequence Viewer
	EDM08646	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015521
	ENSRNOP00000088247
GenBank Protein	P23377	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_062204 ⟸ NM_019331
- Peptide Label:	precursor
- UniProtKB:	P23377 (UniProtKB/Swiss-Prot), G3V7I9 (UniProtKB/TrEMBL), A6JCC0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELRPWLLWVVAAAGALVLLAAEARGQKIFTNTWAVHISGGPAVADSVARKHGFHNLGQIFGDY YHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEPTDPKFPQQWYLSGVT QRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQR KCIIEILAEPKDIGKRLEVRKTVTACLGEPNHISRLEHVQARLTLSYNRRGDLAIHLISPMGTR STLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASE GLSAPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQRCPPGFTPQVLDTHYSTENDVEIIRASV CTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSRESRPQQPPPALRPEVEVEPRL RAGLASHLPEVLAGLSCLIIALIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQE ECPSDSEEDEGRGERTAFIKDQSAL hide sequence

RefSeq Acc Id:

XP_008757777 ⟸ XM_008759555

- Peptide Label:

isoform X1

- Sequence:

show sequence

MELRPWLLWVVAAAGALVLLAAEARGQKIFTNTWAVHISGGPAVADSVARKHGFHNLGQIFGDY
YHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKQRAKRDVYQEPTDPKFPQQWYLSGVT
QRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN
RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP
EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA
TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA
NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQR
KCIIEILAEPKDIGKRLEVRKTVTACLGEPNHISRLEHVQARLTLSYNRRGDLAIHLISPMGTR
STLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASE
GLSAPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQRCPPGFTPQVLDTHYSTENDVEIIRASV
CTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSRESRPQQPPPALRPEVEVEPRL
RAGLASHLPEVLAGLSCLIIALIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQE
ECPSDSEEDEGRGERTAFIKDQSAL

hide sequence

Ensembl Acc Id:

ENSRNOP00000015521 ⟸ ENSRNOT00000015521

Ensembl Acc Id:

ENSRNOP00000088247 ⟸ ENSRNOT00000116325

Ensembl Acc Id:

ENSRNOP00000088681 ⟸ ENSRNOT00000102738

RefSeq Acc Id:	XP_063128021 ⟸ XM_063271951
- Peptide Label:	isoform X1
- UniProtKB:	P23377 (UniProtKB/Swiss-Prot), A6JCC0 (UniProtKB/TrEMBL), G3V7I9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128016 ⟸ XM_063271946
- Peptide Label:	isoform X1
- UniProtKB:	P23377 (UniProtKB/Swiss-Prot), A6JCC0 (UniProtKB/TrEMBL), G3V7I9 (UniProtKB/TrEMBL)

Protein Domains

P/Homo B Peptidase S8

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P23377-F1-model_v2	AlphaFold	P23377	1-793	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690149

Promoter ID:

EPDNEW_R671

Type:

multiple initiation site

Name:

Furin_1

Description:

furin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	142,197,256 - 142,197,316	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3274	AgrOrtholog
BioCyc Gene	G2FUF-58730	BioCyc
Ensembl Genes	ENSRNOG00000011352	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000015521	ENTREZGENE
	ENSRNOT00000116325	ENTREZGENE
Gene3D-CATH	3.30.70.850	UniProtKB/Swiss-Prot
	3.40.50.200	UniProtKB/Swiss-Prot
	Galactose-binding domain-like	UniProtKB/Swiss-Prot
	Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2	UniProtKB/Swiss-Prot
InterPro	Furin_repeat	UniProtKB/Swiss-Prot
	Galactose-bd-like_sf	UniProtKB/Swiss-Prot
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot
	Kexin/furin	UniProtKB/Swiss-Prot
	P_dom	UniProtKB/Swiss-Prot
	Peptidase_S8/S53_dom	UniProtKB/Swiss-Prot
	Peptidase_S8/S53_dom_sf	UniProtKB/Swiss-Prot
	Peptidase_S8_Asp-AS	UniProtKB/Swiss-Prot
	Peptidase_S8_His-AS	UniProtKB/Swiss-Prot
	Peptidase_S8_Ser-AS	UniProtKB/Swiss-Prot
	Peptidase_S8_subtilisin-rel	UniProtKB/Swiss-Prot
	S8_pro-domain	UniProtKB/Swiss-Prot
	S8_pro-domain_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:54281	UniProtKB/Swiss-Prot
NCBI Gene	54281	ENTREZGENE
PANTHER	FURIN	UniProtKB/Swiss-Prot
	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED	UniProtKB/Swiss-Prot
Pfam	P_proprotein	UniProtKB/Swiss-Prot
	Peptidase_S8	UniProtKB/Swiss-Prot
	S8_pro-domain	UniProtKB/Swiss-Prot
PhenoGen	Furin	PhenoGen
PRINTS	SUBTILISIN	UniProtKB/Swiss-Prot
PROSITE	P_HOMO_B	UniProtKB/Swiss-Prot
	SUBTILASE	UniProtKB/Swiss-Prot
	SUBTILASE_ASP	UniProtKB/Swiss-Prot
	SUBTILASE_HIS	UniProtKB/Swiss-Prot
	SUBTILASE_SER	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000011352	RatGTEx
SMART	SM00261	UniProtKB/Swiss-Prot
Superfamily-SCOP	Protease propeptides/inhibitors	UniProtKB/Swiss-Prot
	SSF49785	UniProtKB/Swiss-Prot
	SSF52743	UniProtKB/Swiss-Prot
	SSF57184	UniProtKB/Swiss-Prot
TIGR	TC204992
UniProt	A0A8I6A642_RAT	UniProtKB/TrEMBL
	A0A8I6A6N7_RAT	UniProtKB/TrEMBL
	A6JCC0	ENTREZGENE, UniProtKB/TrEMBL
	FURIN_RAT	UniProtKB/Swiss-Prot
	G3V7I9	ENTREZGENE, UniProtKB/TrEMBL
	P23377	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-15	Furin	furin (paired basic amino acid cleaving enzyme)	Pcsk3	proprotein convertase subtilisin/kexin type3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-02-23	Pcsk3	proprotein convertase subtilisin/kexin type3	Furin_predicted	furin (paired basic amino acid cleaving enzyme) (predicted)	Data merged from RGD:1311616	737654	APPROVED
2005-01-12	Furin_predicted	furin (paired basic amino acid cleaving enzyme) (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Pcsk3	Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein)			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)