Advanced Search (OLGA)

Gene: Bsn (bassoon (presynaptic cytomatrix protein)) Rattus norvegicus

Analyze

Symbol:

Bsn

Name:

bassoon (presynaptic cytomatrix protein)

RGD ID:

2223

Description:

Enables dynein light chain binding activity; enzyme inhibitor activity; and transcription corepressor binding activity. Involved in several processes, including presynaptic active zone assembly; regulation of ubiquitin protein ligase activity; and retrograde axonal transport. Located in several cellular components, including axon cytoplasm; cytoplasmic vesicle; and cytoskeleton of presynaptic active zone. Is active in several cellular components, including GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; and presynaptic active zone cytoplasmic component. Colocalizes with synaptic membrane. Orthologous to human BSN (bassoon presynaptic cytomatrix protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

bassoon; neuronal double zinc finger protein; zinc finger protein 231; Znf231

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BSN (bassoon presynaptic cytomatrix protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Bsn (bassoon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bsn (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BSN (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BSN (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bsn (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BSN (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BSN (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bsn (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Bsn (bassoon presynaptic cytomatrix protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Bsn (bassoon)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BSN (bassoon presynaptic cytomatrix protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bsnb (bassoon (presynaptic cytomatrix protein) b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bsnb (bassoon (presynaptic cytomatrix protein) b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bsna (bassoon presynaptic cytomatrix protein a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bsna (bassoon presynaptic cytomatrix protein a)	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	cla-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	bsn	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	bsn	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Bsn^em1Ionsz

Genetic Models:

SD-Bsn^em1Ionsz

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,663,447 - 117,754,412 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,670,334 - 117,754,412 (-)	Ensembl				GRCr8
mRatBN7.2	8	108,784,849 - 108,875,819 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,788,542 - 108,875,819 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,411,051 - 114,502,023 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,610,375 - 112,701,351 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,453,016 - 110,543,985 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,873,721 - 116,965,396 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,873,721 - 116,965,396 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,227,802 - 116,319,071 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,364,208 - 113,455,766 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	108,089,061 - 108,180,178 (-)	NCBI		Celera
RGSC_v3.1	8	113,387,192 - 113,475,221 (-)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

epilepsy (ISO,ISS)

heart disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

amitrole (EXP)

amphetamine (EXP)

androgen antagonist (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

bisphenol AF (EXP)

Brodifacoum (EXP)

Butylparaben (EXP)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

clobetasol (ISO)

DDE (EXP,ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

doxorubicin (ISO)

enzacamene (EXP)

epoxiconazole (EXP)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

genistein (ISO)

lidocaine (EXP)

linuron (EXP)

manganese(II) chloride (EXP)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

miconazole (ISO)

O-methyleugenol (ISO)

paracetamol (EXP,ISO)

prochloraz (EXP)

procymidone (EXP)

quercetin (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

titanium dioxide (EXP,ISO)

tributylstannane (EXP)

trichloroethene (EXP)

triptonide (ISO)

tunicamycin (ISO)

valproic acid (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axo-dendritic transport (IDA)

cytoskeleton organization (NAS)

maintenance of presynaptic active zone structure (IEA)

modulation of chemical synaptic transmission (IDA)

presynaptic active zone assembly (IBA,IDA,IEA)

protein localization to synapse (IBA,IEA,ISO)

regulation of synaptic vesicle cycle (IEA,ISO)

regulation of ubiquitin protein ligase activity (IDA)

retrograde axonal transport (IDA)

synapse organization (IDA)

synaptic vesicle clustering (IEA,ISO)

Cellular Component

axon (IBA,IEA,ISO)

axon cytoplasm (IDA)

cell cortex (IDA)

cell surface (IEA,ISO)

cochlear hair cell ribbon synapse (IEA,ISO)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

cytoskeleton (IEA)

cytoskeleton of presynaptic active zone (IBA,IDA,IEA)

dendrite (IEA,ISO)

excitatory synapse (IDA)

GABA-ergic synapse (IBA,IDA,IEA,ISO)

glutamatergic synapse (IBA,IDA,IEA,ISO)

Golgi-associated vesicle (IDA,IEA)

hippocampal mossy fiber to CA3 synapse (IDA)

inhibitory synapse (IDA,IEA)

neuron projection terminus (IEA,ISO)

neuronal cell body (IDA)

piccolo-bassoon transport vesicle (IDA)

postsynaptic density (IEA,ISO)

presynapse (IEA,ISO)

presynaptic active zone (IDA,IEA,ISO)

presynaptic active zone cytoplasmic component (IDA)

ribbon synapse (IDA,IEA)

Schaffer collateral - CA1 synapse (IEA,ISO)

synapse (IEA,ISO)

synaptic membrane (IDA)

synaptic vesicle (IDA)

synaptic vesicle membrane (IEA)

trans-Golgi network (IDA,IEA)

Molecular Function

dynein light chain binding (IPI)

enzyme inhibitor activity (IDA)

metal ion binding (IEA)

protein binding (IPI,ISO)

structural constituent of presynaptic active zone (IBA,IEA,ISO)

transcription corepressor binding (IEA,IPI)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif.	Burkhardt C, etal., FEBS Lett. 2005 Jul 4;579(17):3821-8.
2.	Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon.	Dick O, etal., J Comp Neurol. 2001 Oct 15;439(2):224-34.
3.	Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment.	Dresbach T, etal., J Biol Chem. 2006 Mar 3;281(9):6038-47. Epub 2005 Dec 21.
4.	Myotonia congenita with strabismus in a large family with a mutation in the SCN4A gene.	Du H, etal., Eye (Lond). 2012 Aug;26(8):1039-43. doi: 10.1038/eye.2012.80. Epub 2012 Jun 1.
5.	Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon.	Fejtova A, etal., J Cell Biol. 2009 Apr 20;185(2):341-55. doi: 10.1083/jcb.200807155.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
8.	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	Ivanova D, etal., EMBO J. 2015 Apr 15;34(8):1056-77. doi: 10.15252/embj.201488796. Epub 2015 Feb 4.
9.	Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.	Ko J, etal., EMBO J. 2009 Oct 21;28(20):3244-55. doi: 10.1038/emboj.2009.249. Epub 2009 Sep 3.
10.	Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover.	Körber C, etal., Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001. Epub 2015 Jul 23.
11.	Formation of Golgi-derived active zone precursor vesicles.	Maas C, etal., J Neurosci. 2012 Aug 8;32(32):11095-108. doi: 10.1523/JNEUROSCI.0195-12.2012.
12.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
13.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
14.	Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.	Ohtsuka T, etal., J Cell Biol 2002 Aug 5;158(3):577-90. Epub 2002 Aug 5.
15.	D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.	Popiolek M, etal., J Biol Chem. 2011 Aug 19;286(33):28867-28875. doi: 10.1074/jbc.M111.262063. Epub 2011 Jun 23.
16.	GOA pipeline	RGD automated data pipeline
17.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
19.	Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brain.	Richter K, etal., J Comp Neurol. 1999 Jun 7;408(3):437-48.
20.	Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals.	tom Dieck S, etal., J Cell Biol 1998 Jul 27;142(2):499-509.
21.	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	Waites CL, etal., EMBO J. 2013 Apr 3;32(7):954-69. doi: 10.1038/emboj.2013.27. Epub 2013 Feb 12.

Additional References at PubMed

PMID:8889548	PMID:10564375	PMID:10900017	PMID:12115694	PMID:12812759	PMID:14622577	PMID:14734538	PMID:15340146	PMID:15935055	PMID:17114649	PMID:19966281	PMID:20127803
PMID:21092860	PMID:21144999	PMID:21356198	PMID:21712437	PMID:21940441	PMID:22701595	PMID:22871113	PMID:23516560	PMID:23791195	PMID:24554721	PMID:26793095	PMID:27907191
PMID:29476059	PMID:30053369	PMID:32651614

Genomics

Comparative Map Data

Bsn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,663,447 - 117,754,412 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,670,334 - 117,754,412 (-)	Ensembl				GRCr8
mRatBN7.2	8	108,784,849 - 108,875,819 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,788,542 - 108,875,819 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,411,051 - 114,502,023 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,610,375 - 112,701,351 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,453,016 - 110,543,985 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,873,721 - 116,965,396 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,873,721 - 116,965,396 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,227,802 - 116,319,071 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,364,208 - 113,455,766 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	108,089,061 - 108,180,178 (-)	NCBI		Celera
RGSC_v3.1	8	113,387,192 - 113,475,221 (-)	NCBI
Cytogenetic Map	8	q32	NCBI

BSN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	49,554,477 - 49,673,130 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	49,554,477 - 49,671,549 (+)	Ensembl			hg38	GRCh38
GRCh37	3	49,591,910 - 49,708,982 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,566,926 - 49,683,986 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	49,566,925 - 49,683,980	NCBI
Celera	3	49,556,534 - 49,673,679 (+)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,651,449 - 49,767,966 (+)	NCBI		HuRef
CHM1_1	3	49,544,319 - 49,661,041 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	49,583,475 - 49,700,809 (+)	NCBI		T2T-CHM13v2.0

Bsn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,973,221 - 108,067,618 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,973,221 - 108,067,583 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	108,096,022 - 108,190,419 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,096,022 - 108,190,384 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	107,998,353 - 108,092,714 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,961,291 - 108,048,359 (-)	NCBI		MGSCv36	mm8
Celera	9	107,705,791 - 107,798,925 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	59.07	NCBI

Bsn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,527,477 - 1,570,670 (+)	Ensembl
ChiLan1.0	NW_004955532	1,527,336 - 1,578,394 (+)	NCBI	ChiLan1.0	ChiLan1.0

BSN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	49,537,981 - 49,653,399 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	49,542,626 - 49,663,680 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	49,483,652 - 49,603,928 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	50,729,927 - 50,841,178 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	50,790,552 - 50,841,178 (+)	Ensembl			panPan2	panpan1.1

BSN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,601,803 - 39,696,831 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,605,117 - 39,642,298 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	39,519,615 - 39,562,116 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,956,213 - 39,998,718 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,956,214 - 40,053,096 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	39,323,297 - 39,368,646 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,726,652 - 39,770,208 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	40,006,478 - 40,050,065 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	64,422,347 - 64,527,292 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	1,182,810 - 1,280,657 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	1,182,872 - 1,287,794 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BSN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,159,630 - 32,195,578 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	32,106,967 - 32,203,461 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	35,341,713 - 35,382,661 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BSN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	10,953,901 - 11,066,892 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	11,018,966 - 11,059,701 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	155,934,160 - 156,048,808 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bsn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	3,498,257 - 3,593,450 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	3,498,118 - 3,600,488 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Bsn
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	99,427,841 - 99,517,738 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Bsn
659 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	416
Count of miRNA genes:	220
Interacting mature miRNAs:	281
Transcripts:	ENSRNOT00000042528
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

D8Rat67

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	117,715,258 - 117,715,446 (+)	Marker Load Pipeline
mRatBN7.2	8	108,836,661 - 108,836,849 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,926,242 - 116,926,429	NCBI	Rnor6.0
Rnor_5.0	8	116,279,875 - 116,280,062	UniSTS	Rnor5.0
RGSC_v3.4	8	113,416,429 - 113,416,799	RGD	RGSC3.4
RGSC_v3.4	8	113,416,613 - 113,416,800	UniSTS	RGSC3.4
Celera	8	108,140,920 - 108,141,107	UniSTS
RGSC_v3.1	8	113,435,884 - 113,436,254	RGD
RH 3.4 Map	8	1118.6	UniSTS
RH 3.4 Map	8	1118.6	RGD
RH 2.0 Map	8	874.3	RGD
SHRSP x BN Map	8	71.8999	RGD
Cytogenetic Map	8	q32	UniSTS

D8Wox32

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,793,202 - 108,793,463 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,882,075 - 116,882,335	NCBI	Rnor6.0
Rnor_5.0	8	116,236,156 - 116,236,416	UniSTS	Rnor5.0
RGSC_v3.4	8	113,372,562 - 113,372,826	UniSTS	RGSC3.4
Celera	8	108,097,417 - 108,097,677	UniSTS
Cytogenetic Map	8	q32	UniSTS

BF387500

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,786,414 - 108,786,571 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,875,287 - 116,875,443	NCBI	Rnor6.0
Rnor_5.0	8	116,229,368 - 116,229,524	UniSTS	Rnor5.0
RGSC_v3.4	8	113,365,774 - 113,365,930	UniSTS	RGSC3.4
Celera	8	108,090,629 - 108,090,785	UniSTS
RH 3.4 Map	8	1116.7	UniSTS
Cytogenetic Map	8	q32	UniSTS

BE097610

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,790,188 - 108,790,380 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,879,061 - 116,879,252	NCBI	Rnor6.0
Rnor_5.0	8	116,233,142 - 116,233,333	UniSTS	Rnor5.0
RGSC_v3.4	8	113,369,548 - 113,369,739	UniSTS	RGSC3.4
Celera	8	108,094,403 - 108,094,594	UniSTS
RH 3.4 Map	8	1120.9	UniSTS
Cytogenetic Map	8	q32	UniSTS

D8Wox11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	117,663,278 - 117,663,387 (+)	Marker Load Pipeline
mRatBN7.2	8	108,784,680 - 108,784,789 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,873,553 - 116,873,661	NCBI	Rnor6.0
Rnor_5.0	8	116,227,634 - 116,227,742	UniSTS	Rnor5.0
RGSC_v3.4	8	113,364,040 - 113,364,148	UniSTS	RGSC3.4
Celera	8	108,088,893 - 108,089,001	UniSTS
Cytogenetic Map	8	q32	UniSTS

Genetic Models

This gene Bsn is modified in the following models/strains:

SD-Bsn^em1Ionsz

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	8	64	164	74	73	42	64	42	6	283	158	10	143	65	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE105137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB580320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y16563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000042528 ⟹ ENSRNOP00000039162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	8	116,873,721 - 116,965,396 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082113 ⟹ ENSRNOP00000072024

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,670,334 - 117,754,412 (-)	Ensembl
mRatBN7.2 Ensembl	8	108,788,542 - 108,875,819 (-)	Ensembl
Rnor_6.0 Ensembl	8	116,877,251 - 116,893,057 (-)	Ensembl

RefSeq Acc Id:

NM_019146 ⟹ NP_062019

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,663,447 - 117,754,412 (-)	NCBI
mRatBN7.2	8	108,784,849 - 108,875,819 (-)	NCBI
Rnor_6.0	8	116,873,721 - 116,965,396 (-)	NCBI
Rnor_5.0	8	116,227,802 - 116,319,071 (-)	NCBI
RGSC_v3.4	8	113,364,208 - 113,455,766 (-)	RGD
Celera	8	108,089,061 - 108,180,178 (-)	RGD

Sequence:

show sequence

AGATGGCGGCAGCTGCGGTGGAGCGGAGAGTGTGAGCGCCGCCCGGGAGCCGCCGGCCCGGGCG
CAGTGCGACCCCGACCCCGCCCGCCCGCCTGCCCACCATGGGCAACGAGGCCAGCCTGGAGGGC
GGCGCGGGCGAAGGGCCGCTGCCGCCGGGAGGCTCTGGTCTGGGTCCGGGCCCCGGAGCAGGGA
AGCCGCCTTCAGCACTAGCTGGCGGCGGACAGCTCCCCGTGGCTGGTGCTGCGCGAGCGGCGGG
ACCCCCGACCCCTGGTCTCGGTCTGGTCCCCGGCCCTGGTCCCGGCCCCGGCCCGGGCAGTGTT
TCCCGGAGACTGGACCCCAAGGAGCCCCTGGGCAGCCAGAGAGCAACTTCTCCAACCCCAAAGC
AAGCTTCTGCTACTGCTCCTGGCCGAGAGAGCCCCCGAGAGACAAGGGCCCAAGGCCTGTCAGG
CCAGGAGGCCGAAGGTCCCCGCAGGACACTGCAGGTAGACAGCAGGACACAGAGATCAGGACGG
TCCCCCTCCGTGTCACCAGACAGAGGCAGCACTCCCACATCACCCTATTCCGTCCCCCAGATTG
CCCCTCTTCCCAGCAGCACCCTGTGTCCAATATGCAAGACATCGGACCTCACATCAACCTCCAG
CCAGCCAAACTTCAACACCTGCACCCAGTGTCACAACAAGGTCTGCAACCAATGTGGGTTCAAC
CCCAACCCTCACCTCACCCAGGTGAAGGAGTGGCTCTGTTTGAACTGTCAGATGCAGAGGGCCC
TGGGAATGGACATGACCACTGCACCTCGGTCCAAGAGCCAGCAGCAGCTACACTCCCCGGCCCT
GTCTCCTGCCCACTCCCCAGCCAAACAGCCTCTGGGGAAGCCAGAGCAAGAGAGATCTCGGAGC
CCAGGGGCCACACAGTCTGGTCCCCGCCAGGCTGAAGCAGCCAGGGCCACCTCAGTGCCTGGGC
CTACCCAGGCAACTGCCCCTCCAGAGGTGGGGAGGGTGTCTCCTCAGCCCCCTCTCTCTACCAA
GCCTTCCACAGCTGAGCCCAGGCCACCTGCAGGAGAGGCCCAGGGCAAAAGTGCCACCACAGTG
CCCTCCGGGCTTGGTGCTGCTGAACAGACCCAGGAGGGGCTCACCGGGAAGCTCTTTGGCCTTG
GAGCATCACTGCTGACCCAGGCAAGCACCCTTATGTCTGTGCAGCCAGAGGCTGACACCCAGGG
CCAGCCTTCCCCCAGCAAGGGGCCACCCAAGATTGTCTTCAGTGATGCCAGCAAGGAGGCGGGT
CCAAGACCCCCAGGCTCAGGGCCCGGGCCTGGGCCAACCCCTGGAGCCAAAACGGAGCCTGGGC
CTAGAACAGGTCCTGGATCAGGGCCTGGGGCCCTGGCAAAAACTGGAGGAACCCCCAGTCCAAA
GCATGGCAGAGCAGACCATCAGGCAGCATCCAAAGCTGCTGCCAAGCCAAAGACCATGCCGAAG
GAAAGGGCTGCCTGCCCACTGTGCCAAGCCGAGCTCAACGTGGGTAGCAGGGGCCCAGCCAACT
ACAATACCTGCACTGCCTGCAAGCTCCGGGTGTGCACCCTGTGTGGCTTTAACCCGACACCACA
CCTGGTGGAGAAAACAGAGTGGCTCTGTCTGAACTGCCAAACCAAGAGGCTGCTGGAGGGCAGC
TTGGGGGAGCCGGCCCCCCTGCCTCTGCCCACCCCACAGCAGCCTCCAGCAGGGGTCCCTCAGC
GAGCAGCTGGAGCAAGTCCTCTGAAGCAGAAAGGGCCACAGGGGCCGGGCCAGCCCTCAGGCTC
CCTGCCTCCCAAGGCCAGTCCTCAAGCCGCCAAGGCCAGCCCTCAGGCCGCCAAGGCCAGCCCT
CAGGCCAAGCCTCTCAGGGCTTCTGAACCCAGCAAGACCTCTAGCAGCGCCCCGGAAAAGAAGA
CAGGGATCCCTGTGAAAGCTGAGCCTGTGCCGAAGCCACCTCCAGAGACTGCTGTGCCTCCTGG
GACTCCTAAAGCAAAAAGCGGGGTGAAGAGGACCGACCCTGCCACCCCAGTCGTCAAGCCTGTT
CCAGAAGCTCCCAAGAGCGGGGAGGCTGAGGAACCTGTCCCCAAGCCTTACTCTCAGGATCTGT
CTCGAAGCCCACAAAGCCTCAGTGATACAGGCTACTCCTCCGATGGCGTCTCCAGCTCCCAGAG
TGAGATCACAGGTGTTGTACAGCAAGAAGTGGAGCAACTTGACAGTGCGGGGGTGACAGGCCCA
CGTCCACCCAGCCCCTCAGAGCTCCACAAAGTGGGCAGTAGTATGCGCCCTTCCCTGGAGGCCC
AGGCTGTGGCTCCCAGTGGTGAGTGGAGCAAGCCACCCAGCGGCAGTGCTGTTGAAGACCAGAA
ACGGCGTCCCCACTCCCTGTCCATCATGCCCGAGGCCTTCGACTCTGACGAGGAGCTGGGGGAT
ATTCTAGAAGAGGATGACTCCTTGGCATGGGGGCGTCAGAGGGAGCAGCAAGACACAGCTGAGT
CTTCAGATGACTTTGGCAGCCAGCTGAGGCATGACTACGTGGAAGACAGCAGTGAAGGCGGCTT
GTCTCCCCTTCCACCTCAGCCCCCAGCCAGGGCAGATATGACTGATGAAGAGTTCATGCGGCGG
CAGATCCTAGAAATGAGCGCCGAGGAAGACAACTTGGAGGAAGACGACACCGCTGTCTCCGGGC
GAGGCCTGGCCAAACACGGTGCCCAGAAGGCAAGTGCCAGACCCAGGCCCGAATCTAGCCAAGA
ATCAGTAGCACTGCCCAAGAGGCGCCTGCCCCATAATGCCACCACAGGTTACGAGGAACTTCTG
TCTGAGGAAGGCCCAGCAGAGCCCACTGACGGAGCCCTTCAGGGAGGTCTCCGACGCTTTAAAA
CTATTGAGCTCAACAGCACAGGTAGCTATGGTCACGAGCTAGACCTGGGCCAAGGCTCTGATCC
CAACCTAGACCGGGAGCCTGAGCTGGAGATGGAGAGCCTTACAGGCTCGCCTGAAGACCGCTCT
CGTGGGGAGCACTCCTCTACACTGCCGGCTTCCACGCCTAGCTATACATCTGGCACCTCACCCA
CCTCCCTGTCTTCCCTGGAGGAGGACAGTGACAGCAGCCCCAGCCGCAGGCAGCGGCTAGAAGA
AGCGAAGCAGCAGCGCAAGGCCCGGCACCGGTCCCACGGGCCCCTGCTGCCCACCATTGAGGAC
TCTTCCGAGGAGGAGGAGCTGCGGGAAGAAGAGGAGCTGCTGCGTGAGCAAGAGAAGATGCGGG
AGGTGGAACAGCAGCGAATTCGAAGCACAGCCCGCAAGACCCGGCGTGACAAGGAAGAACTTCG
GGCTCAGCGGCGGCGTGAGCGCTCCAAGACACCGCCTAGTAACCTGTCACCCATCGAAGATGCG
TCCCCTACAGAGGAGCTGAGGCAGGCAGCGGAGATGGAGGAGCTACACCGCTCTTCCTGCTCTG
AGTACTCCCCCTCCCCCTCCCTGGACTCAGAGGCTGAGACCCTCGATGGCGGCCCCACTCGGCT
CTACAAGTCGGGCAGCGAGTACAACCTGCCTGCCTTTATGTCCCTCTGCTCACCAACCGAGACC
CCTTCAGGCAGTTCCACCACGCCCAGTTCTGGACGGCCCCTTAAGAGTGCGGAGGAGGCCTACG
AGGACATGATGAGAAAAGCTGAGCTGCTCCAGAGACAGCAGGGCCAGGCGGCAGGGGCCCGGGG
ACCCCATGGCGGCCCCTCTCAGCCCACAGGCCCCCGCAGCCAGGGCTCCTTTGAATACCAAGAC
ACCCAAGACCATGACTATGGCGGCAGGGCTTCTCAGCCTGCGGCAGATGGCACGCCCGCAGGCC
TCGGAGCAACAGTGTATGAGGAGATCCTTCAGACATCCCAGAGCATAGCCCGGATGCGGCAGGC
CTCCTCGCGGGATCTGGCCTTCACTGAGGACAAAAAGAAGGAGAAGCAGTTTCTGAATGCGGAG
AGTGCATACATGGACCCAATGAAGCAAAATGGTGGCCCACTTACCCCTGGGACTAGCCCCACCC
AACTTGCTGCTCCTGTGTCATTTCCCACTTCCACCTCCTCAGACAGCAGCGGGGGCCGAGTTAT
TCCCGATGTCAGAGTCACTCAGCATTTTGCAAAAGAGCCTCAGGAGCCTCTCAAGCTACATAGC
TCTCCTGCCTCTCCCAGTCTGGCCTCTAAGGAGGTAGGCATGACCTTCTCCCAGGGTCCTGGAA
CTCCAGCCACCACAGCCATGGCGCCTTGTCCAGCCAGCCTTCCACGGGGGTATATGACTCCAGC
CGGCCCTGAGCGCAGCCCATCAACATCTTCCACAATACACAGCTATGGACAGCCCCCAACCACT
GCTAACTATGGGTCTCAGACGGAGGAGCTGCCTCACGCTCCCAGTGGCCCTGCTGGAAGTGGGC
GGGCCTCCAGAGAGAAGCCTCTGAGTGGGGGTGATGGTGAGGTTGGTCCCCCCCAGCCTTCTCG
GGGATATTCTTATTTTACGGGCTCTAGCCCACCTCTCTCTCCATCCACCCCCTCCGAGAGCCCC
ACCTTCTCTCCAAGCAAGCTGGGTCCAAGGGCCACAGCAGAGTTCTCTACACAGACGCCAAGCC
TAACGCCTTCCTCTGACATTCCACGGAGCCCTGGCACCCCTTCCCCCATGGTAGCCCAAGGCAC
GCAGACGCCACACCGACCTAGCACTCCTCGCTTGGTGTGGCAGCAGTCTTCCCAGGAGGCTCCT
GTTATGGTCATCACGCTAGCTTCAGATGCTTCTAGCCAGACCCGAATGGTACACGCCAGTGCCT
CTACTTCCCCTCTGTGCTCGCCTACGGACTCTCAGCCTGCCTCCCATAGCTACAGCCAGACCAC
ACCCCCAAGTGCATCTCAAATGCCCTCAGAACCAGCTGGGCCACCTGGTTTCCCACGAGCACCC
AGTGCTGGTGTAGACGGGCCATTGGCGCTGTATGGCTGGGGTGCCCTCCCTGCTGAAAACATCT
CCTTATGCCGGATCTCCTCTGTCCCTGGAACATCTAGAGTTGAGCCGGGCCCCAGGCCCCCGGG
CACCGCAGTGGTCGACCTTCGCACGGCTGTCAAGCCCACACCCATTATCCTTACCGACCAGGGC
ATGGATCTGACCTCTCTTGCTGTGGAAGCAAGGAAGTATGGCCTTGCCCTGGATCCAGTTCCAG
GCCGCCAGTCAACCGCCGTGCAGCCTCTAGTTATTAACCTCAATGCCCAAGAGCAGACCCATAC
CTTCCTGGCCACTGCCACCACAGTGAGCATCACCATGGCCTCATCTGTGCTCATGGCGCAGCAA
AAGCAACCAGTGGTATATGGAGATCCTTTCCAGAGCCGCCTCGACTTTGGCCAGGGTTCAGGTA
GCCCTGTGTGCCTGGCCCAGGTCAAGCAAGTAGAGCAGGCTGTCCAGACAGCCCCATACCGAGG
TGGGCCCAGGGGAAGACCCAGGGAGGCTAAGTTCGCCAGGTATAACCTTCCCAACCAGGTAACA
CCTCTGGCCAGAAGGGACATTCTGATCACTCAGATGGGCACTGCCCAGAGTGTTAGCCTGAAGC
CAGGACCAGTGCCAGAGCCTGGTGCTGAACCCCACCGGGCTACTCCTGCAGAGCTCCGGGCACA
TGCTCTACCAGGTACCAGGAAGCCACACACAGTGGTGGTGCAGATGGGAGAGGGCGCAGCCGGC
ACGGTGACTACCCTGCTCCCAGAAGAGCCAGCAGGAGCCCTGGACCTCACTGGGATGAGGCCCG
AGAGCCGACTGGCATGCTGTGACATGGCCTATAAGTTTCCCTTTGGCAGTAGCTGCACTGGTAC
CTTCCATCCTGCCCCTAGTGCACCTGACAAGAGTGTGACAGATGCTGCCCTGCCTGGCCAAAGC
AGTGGCCCCTTCTACAGTCCCAGAGACCCTGAGCCTCCTGAGCCCCTCACCTTCCGGGCACAAG
GGGTCGTAGGACCTGGGCCCCATGAAGAACAGAGGCCCTACCCACAGGGCTTGCCCGGTAGGCT
CTACTCCTCCATGTCTGACACCAATTTGGCTGAAGCTGGTCTCAACTACCACGCCCAGAGGATT
GGGCAGCTCTTCCAGGGCCCTGGGAGGGACTCAGCTGTGGATCTCAGCTCGCTGAAGCATTCTT
ACAGCTTAGGCTTCGCTGATGGACGCTACTTGGGGCAGGGCTTACAGTATGGCTCGTTCACGGA
CCTGCGCCACCCCACAGACCTTTTGTCTCACCCACTGCCCATGAGGCGCTACAGCTCTGTGTCA
AACATCTATTCGGATCACCGGTACGGCCCACGGGGAGATGCCGTCGGCTTTCAGGAGGCCAGCC
TGGCCCAGTACAGTGCCACCACAGCCCGCGAGATCAGCCGCATGTGTGCCGCCCTCAACTCCAT
GGACCAGTACGGTGGGCGGCATGGCGGTGGAAGTGGTGGGCCCGACCTTGTGCCGTATCAGCCC
CAGCACGGGCCTGGACTCAATGCTCCACAGGGTCTGGCTTCCCTTAGATCTGGCCTCCTCGGCA
ACCCCACCTACCCAGAAGGGCAACCAAGTCCTGGGAACCTTGCTCAGTACGGGCCTGCAGCAAG
CCAAGGAACAGCAGTCAGACAGTTGCTCCCATCCACAGCAACAGTGCGTGCAGCCGATGGCATG
ATCTACTCGACTATCAATACCCCAATCGCTGCAACACTGCCCATCACCACCCAGCCTGCCTCAG
TACTGCGGCCCATGGTGCGTGGTGGCATGTACAGGCCTTACGGATCTGGCGGAGTCACAGCTGT
GCCCCTTACCAGCCTGACCCGGGTGCCCATGATTGCCCCTCGGGTACCTCTTGGACCAGCAGGG
TTATACCGCTATCCTGCACCAAGTCGATTCCCCATCGCTTCCACCATTCCACCCGCTGAAGGAC
CTGTCTATTTGGGAAAGCCAGCAGCCGCCAAGGCCTCGGGGGCAGGAGGCCCGCCAAGGCCTGA
GCTACCAGCAGGGGGTGCTCGAGAAGAACCTCTCTCCACAACTGCCCCTCCTGCTGTCATCAAG
GAAGCCCCGGTGGCCCAGGCCCCGGCCCCACCACCAGGCCAAAAGCCAGCAGGAGATGCTGCTG
CTGGGAGTGGCAGTGGAGTCCTCGGCCGGCCTGTGATGGAGAAGGAGGAGGCATCTCAGGAGGA
CCGGCAGCGAAAGCAACAGGAGCAGCTGCTGCAGCTGGAGCGGGAACGGGTAGAGTTGGAAAAG
CTCCGGCAGTTGCGGCTACAGGAGGAGCTGGAGCGAGAGAGGGTGGAGCTGCAGAGGCATCGTG
AGGAGGAGCAGCTGCTGGTGCAGAGAGAGTTGCAGGAGCTCCAGACCATCAAGCACCATGTTCT
GCAGCAGCAGCAAGAAGAGCGCCAAGCTCAGTTCGCACTGCAGCGCGAGCAGCTGGCACAGCAG
CGGCTGCAGCTAGAGCAGATCCAGCAACTGCAGCAGCAGCTGCAGCAGCAGCTAGAGGAGCAGA
AACAGAGGCAAAAGGCCCCCTTTCCTGCAACCTGTGAGGCGCCTAGCCGAGGGCCTCCCCCCGC
TGCTACCGAGCTGGCCCAGAACGGCCAGTATTGGCCACCATTGACCCACACAGCCTTCATCGCC
GTGGCAGGAACCGAAGGGCCTGGGCAAGCTCGTGAGCCCGTGCTGCACAGGGGCCTCCCCAGCT
CTGCCTCAGACATGTCCCTGCAAACTGAGGAGCAGTGGGAGGCAGGCCGTAGTGGCATCAAGAA
ACGTCACTCTATGCCACGCCTGAGAGACGCCTGTGAACCAGAGTCAGGCCCTGATCCCAGCACG
GTCAGGAGGATTGCAGACAGCAGTGTTCAGACAGATGATGAGGAGGGCGAGGGCCGCTACCTCC
TGACCCGTAGGCGCAGGACACGGCGCAGTGCCGACTGCAGTGTGCAGACAGATGACGAGGACAA
TGCCGAATGGGAGCAGCCTGTCCGCCGCCGCAGGTCTCGTCTTTCCCGTCACTCAGACTCAGGC
TCTGACAGCAAGCACGAGGCCTCGGCCTCATCGTCCGCTGCTGCCGCTGCGGCGAGGGCCATGA
GCAGTGTGGGTATCCAGACCATCAGTGACTGCTCTGTACAGACAGAGCCTGAGCAGCTGCCCAG
GGTCTCACCAGCCATCCACATCACAGCCGCCACTGACCCAAAGGTGGAGATCGTCAGATACATA
TCAGCACCAGAAAAGACTGGGCGAGGGGAGAGCCTGGCCTGCCAGACAGAACCCGATGGGCAGG
CTCAGGGTGTGGCTGGGCCACAGCTCATAGGACCAACTGCCATCAGCCCCTACCTACCTGGCAT
CCAGATAGTCACCCCAGGAGCCCTAGGCAGATTTGAAAAGAAGAAGCCAGATCCTCTGGAGATT
GGGTACCAGGCCCACCTGCCCCCGGAGTCCCTGTCGCAGCTTGTGAGCCGCCAGCCTCCCAAGT
CTCCACAAGTGCTCTACTCACCAGTGTCGCCACTGTCCCCACACCGGCTCCTGGACACCTCGTT
TGCTTCCAGTGAGAGGCTGAACAAGGCTCATGTGAGTCCCCAGAAGCAGTTCATAGCTGACAGC
ACTCTTCGCCAGCAGACTCTGCCGCGCCCCATGAAGACCCTGCAGCGGTCCCTGTCCGACCCTA
AGCCCCTGAGCCCCACCGCCGAGGAGTCTGCCAAAGAGAGATTCTCCCTCTACCAGCACCAGGG
GGGACTAGGTAGCCAGGTGTCGGCGCTGCCACCCAACGGCCTGGTCCGCAAGGTGAAGCGGACA
CTGCCCAGCCCCCCTCCAGAGGAAGCTCACCTTCCCCTGGCTGGCCAGGTGCCCTCACAGCTGT
ATGCAGCCAGTCTGCTGCAGCGAGGGTTGGCGGGGCCCACCACCGTCCCTGCTACCAAGGCCAG
CCTGCTCCGGGAGCTGGACCGGGACCTGCGGCTGGTGGAGCATGAATCCACCAAGCTGCGCAAG
AAGCAGGCGGAGTTGGACGAGGAGGAGAAGGAGATTGATGCCAAGCTCAAGTACCTGGAGCTGG
GCATCACCCAGCGCAAAGAGTCTTTGGCCAAAGACCGGGTTGGCCGTGACTACCCACCTTTACG
TGGCCTTGGTGAGCATCGTGACTACCTGTCTGACAGCGAGCTCAACCAGCTGCGGCTCCAGGGT
TGTACCACGCCCGCTGGCCAGTATGTGGACTACCCTGCCTCAGCTGCTGTGCCTGCCACCCCCT
CTGGCCCCACTGCCTTCCAACAGCCCCGGTTCCCACCTGCAGCCACACAGTACACTGCAGGCAG
TAGTGGACCAACTCAGAATGGATTTCTAGCCCACCAGGCACCTACCTACACTGGCCCTAGCACG
TACCCAGCACCTACCTACCCTCCTGGAACGAGTTATCCAGCTGAGCCTGGCCTGCCAAGCCAAC
CGGCTTTCCACCCCACAGGCCATTACGCAGCCCCAACGCCCATGCCAACCACGCAGAGCGCCCC
TTTTCCAGTCCAAGCTGACAGTCACGCTGCCCACCAGAAGCCGCGCCAGACCTCACTGGCTGAT
TTGGAGCAGAAGGTTCCCACCAATTATGAAGTGATCAGCAGCCCTGCTGTAACCGTGTCCTCAA
CCCCCTCTGAGACCGGCTACAGTGGTCCAGCTGTGAGCAGCAGCTACGAGCACGGTAAAGCCCC
TGAGCATCCCCGGGGTGGTGATCGAAGCAGTGTGAGCCAGAGCCCAGCCCCTACATATCCCTCT
GACTCCCATTACACCAGTCTGGAGCAGAACGTTCCCCGAAACTATGTGATGATCGATGACATCA
GTGAGCTAACCAAGGACAGCACCCCCACTGCCTCGGATAGCCAACGGCCAGAGCCCTTGGGCCC
AGGTGGAGTCAGTGGGCGTCCCGGGAAGGATCCCGGAGAACCAGCTGTCCTAGAGGGACCCACT
CTGCCCTGCTGCTATGGCAGAGGTGAGGAAGAATCTGAGGAGGACTCATATGACCCCCGTGGCA
AATCTGGTCATCACCGGAGCATGGAGAGCAACGGCCGACCAGCCAGCACCCACTATTACAGTGA
CAGTGACTATAGACATGGGGCTCGAGCAGACAAGTATGGCCCAGGACCCATGGGGCCAAAGCAT
CCCTCTAAGAACCTGGCCCCGGCTGCCATCTCCTCCAAGCGCAGCAAGCACCGGAAGCAAGGCA
TGGAGCAAAAGATCTCCAAGTTCTCACCTATCGAGGAGGCCAAGGACGTGGAATCAGACCTGGC
CTCCTATCCCCCACCCACCGTCAGCAGCAGCCTGACCTCTCGGAGCAGAAAGTTCCAAGACGAA
ATCACCTATGGGCTCAAGAAGAATGTGTATGAACAGCAGAGGTACTACGGGGTGTCCAGCCGGG
ACACAGCCGAGGAGGATGACCGCATGTATGGTGGTAGCAGCCGGTCCCGAGTGGCATCGGCATA
CAGTGGGGAGAAGCTGTCCAGCCATGATTTCAGCAGCCGAAGCAAAGGGTATGAACGGGAACGG
GAGACTGCAGAGCGACTTCAAAAGGCGGGGCCCAAGCCCTCATCCCTGAGCATGGCTCATGGAC
GGGCACGGCCCCCCATGAGGAGCCAGGCCTCTGAAGAGGAGAGCCCTGTCAGCCCCTTAGGGCG
GCCCCGTCCCGCAGGGGGCGCTCTTCCTCCTGGGGATACCTGCCCACAGTTCTGCTCCAGCCAC
TCCATGCCGGACGTCCAGGAGCACGTCAAGGACGGACCGCGCGCCCACGCATATAAGCGTGAGG
AGGGCTACATCTTGGATGACTCCCACTGCGTGGTTTCGGACAGTGAAGCGTATCACCTGGGCCA
GGAGGAGACAGACTGGTTTGATAAGCCCCGAGATGCCCGCTCCGACCGGTTCAGGCACCATGGG
GGGCATACAGTCTCCTCCTCCCAGAAGCGAGGCCCTGCCAGGCACAGCTACCATGACTACGATG
AGCCCCCTGAGGAGGGCCTGTGGCCTCATGATGAGGGTGGTCCAGGCCGGCATACCTCAGCCAA
GGAGCACCGGCACCACGGTGACCACGGGAGGCACTCAGGCCGCCATGCTGGTGAGGAGCCAGGG
CGCCGTGCTGCCAGACCACATGCTCGGGACATGGGTCGCCACGAGACCCGGCCTCACCCTCAGG
CCAGCCCTGCCCCTGCCATGCAAAAGAAGGGTCAGCCTGGGTACCCCAGCTCTGCTGATTACTC
ACAGCCATCCCGGGCTCCGTCAGCATACCACCATGCCTCTGACAGCAAAAAGGGCTCCCGGCAG
GCCCACTCTGGGCCTACTGTACTGCAGCCAAAGCCAGAAGCCCAGGCACAGCCACAGATGCAAG
GTCGGCAGGCGGTTCCGGGACCGCAGCAATCACAGCCACCATCGTCCAGGCAGACGCCCTCAGG
CACAGCATCACGCCAGCCACAGACACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAA
CAGCAACAGCAGCAACAGCAAGGTCTTGGGCAACAAGCTCCCCAGCAGGCTCCATCACAGGCTC
GGCTACAGCAACAGAGCCAGCCAACCACCCGGAGCACAGCCCCTGCTGCCAGCCACCCAGCAGG
GAAACCTCAACCAGGCCCCACCACAGCCCCAGGGCCCCAGCCAGCAGGACTGCCACGTGCAGAG
CAGGCAGGCAGCTCCAAACCGGCAGCCAAAGCGCCCCAGCAGGGGCGCGCTCCTCAGGCCCAGT
CAGCTCCAGGACCTGCAGGGGCGAAGACTGGAGCCAGGCCTGGGGGGACCCCAGGGGCTCCTGC
TGGTCAGCCAGCGGCAGAAGGAGAGAGTGTATTTTCTAAGATCCTCCCTGGTGGGGCAGCAGAG
CAAGCCGGAAAGCTGACAGAAGCTGTCTCTGCTTTTGGCAAAAAATTTTCCTCATTCTGGTGAT
TGTGTCCAGAAGGGCTCCTGAAGACCTGAAGAAAGACAATCTCATTGCTGTGGAAAAATCTCTG
GAGTCAGAGGCCTGGGTGCAGCTCTGGACTCTGCGTATAACGCATCCACAACCTGGCAAACCTT
TGGCCCAAAGATTCACACCATGTGGGCCCCACCCAGCAGGCAGGCCTCGGCCGAGCATGAGAAT
GCAATGTTTTCTAACAGCAGCGACCTAGGTGAAGCATCTGCTTGCTGGACCAATGGGACCATTG
GCTTGGGGGAACCTTTCATGTCTTTCAAGAGACCCTGCCTTACTCAGGCCAGCCGTCCTTGGGA
GAGAGGAGCCCTCGCCAGAATGCGGTTGCTGCTGAGGCTGTCCGCTGCTTTTCCTGCAGCCTCC
TGTGGCCTGGGCAGCCAGGCTTCCAACGCGTTATACACAGAGTTTGGGTGCACACTACCCTCCC
TCTAAGACACCAGAAGTTTTTTCCACAGCCTTGGAGAGGGGCTTTGACTGAGGGCTGGAGCCCT
AGGCTCCGATTCCTTCACATTCCAGCTGGCCCGGATCCCTCTGTGGCCATGAGGCCTTGCCCGC
TTCACCCTGCTCTGTGGGCGACAATGGAGCAGACCTCCACATGGCCAGCATGGGTTTGGGAGAA
CTTTACAAACATTAGGACCTAACACTGTCTCATCGCTGAAACAAGAGGCCATAGCACCGAAAAG
CAGCGTGGGCACCGGCTGAGGCTTCTCCCAGCCCATGGATGGCAGCGTAACTAAGCATGCCTGC
CATCCTCTTAAAGCCATCCCCCCAGCCATTGTGAGCATCCCAGCAACACCGCCATTGTCTCGAC
CAGCCGGCCCCTCGGCTCCTCATCTGTACACCTGGGGATTTCTTTTGATTTCAGGAACAGCCTT
AATCATTCCAGTTTGATTTACATGTATACCTCACAAACTTTTTTTTTGTTTTATTTTTTTCTTT
CCCTTTCTTTGCTTTTATCCCTCTGTCTCTTCCTCCACCTCCACCCCCACCTCGTGATGGATGG
TTTGGTTTCCTCTCTGCTCTGCCCCTGCTCAGCACAGGGAGAAATGTTGATTTAGAAGCAATAG
CGGGCAGCCGGCCACCAAGAGCACAAACCCAGGGCGAGGTCTAGGGAGGCTCCTCCGCCCGCCT
GTTTACTGTGCAATTCCAGTCCTCTTAAGCCATCAGCAGTAGGTGTGCTCAGAGCAGAGGAGCC
AAGGGGAAGGTTCAGAGCCCTGTGAGGTAAAGGGGAGTATGACACCGTCCATTCACCCGGGGGA
CTGGGCTACACACCTCCCCAAAGCCCTTCCCTCGGAGGCCTCCCTTCATCTCGGGCCCAGCCAC
AAGTCTCATCTCTAATGTTCTATGCAATGAAATATAAACCCTCAAAGACAACTGTTAATATTTA
ATAAATTCCATGTTACATATAAGGAGTTAATTGCAAACACGCAGTTGAGAAACTGGATAGCTCT
ATCTGCTCATACCACCGCCCCAGCCTGATCCTTGTCCCCACTTTCCGTGTGTGTACGTGTGAGA
GCGAAAACGAGAGCATGTATGTACATGTGTGTGCGTGCGTGTATGTTTGTGTGTGTGCGCGGGC
GTGCGTGTGTAAATTCTAAGTCTGTGGCATGTTTGACCTGTGGCAGGACTCGCTGCTTGCCAGG
TGACCCACCGCCTGTCTCGCAGTGGAGCATGCACAGCTCGAAGCTTCTTTGCACGATTTCATTC
ATTTTAAATGCTCGACCTCTTGCTTGGAGTTCTTTTTGCCTCCAAACCTCTCCCTTAAGAGCGC
TTCTCCCTGACTTCGGGACACGCTAGTGAAGACCTCCCAGAACTGCCTGAATATGCCAGGCCAT
GGAGCAGGCCGTGCGGCCCCATACACCTTGCAGTTTTTAATCTGTGTGCGACAGCAGATTAAAA
ACAAACAAACCAACCAACCTTAGAAAAGACAGAGAGAGGAGCCCGCACAGGATGCATGCATATG
AACATTCTATGGGTCTGCTACAGGATCTCTACCTGTGTATCATTTTTCCCTCCTATCCTAGGCC
TGAGCCAAAAGAATCTGGTCACCACTCCCCAGTTGGACACTGCTCAAGAACAAAGCTGGGGTAC
ATCTGTGGAGAGGCAGCAGCCAAGGGATCCTGGCTGTGCCCTACAATCCCTAGATCTTGGCCCT
GCTCTATGTCTCTCCTTTGTGATGTGGAGCCTCAAAGGACTGTGATCCAAGAGATCTGGAATGG
AGCCAGGGGTCATAGGGTACCCAGGAAGAGATGGCTGAAAATATCATTCGGAAAATAACATCCA
CATAAGTAACAGCTTCAAGCTGAGCTCAGGTTTCTCAGGAGCAAAGCTTACCGAAGGGTCTGTG
TAACCCTCTCCACATCTGCCCCAGGACTTGCCTCCTCGGAAACCTAAGTATTACACTGTTGTCA
GTATCTCCCTCACTGGTCCAGGAGTAGAGCAGACAGTACCTGCATGACCCCTAATGTCTGGCCT
GCCTCCAGAGAGTTTTGGTGTACACCACGCATTTCTCAGGGGTTCACATGTCTCATGCTTTTTT
TTTTTTAACAAGGCTTATAACTCCTTTAGAGTGGGACCCTGTCCACCGTTGGCAGCTGTGGATG
GGACACTGAAAACTGTGTTGGACTTAAGAGCCTGAATTCCCAGGATTTAGCTTTCTTCCCACTA
TGTAATATCTCAGTATCTCAAGTTTGATCTCAGAGATCAAACTTGGGTTATATGGGGCCATCTC
TATAAGGGCTGAAGAAGGCCCTCATCGAGGAACTCACAGGCCCAGGTGTGTGCAGGATGTGCCC
AGTGTTCAGATCCTTGGGATCGTGGCAGTATCCCTTCCCACTCATAGTCAGGACTAGGAGATGA
GAGCAGGCAGGGATCCACAGGTCAACCTCTGGCAGCACCCCTAGGCTCAAAAGTATTAATTTTA
CACCAAATTTCTTTTCTGGCTAAACTCCAAGTTTGACATTTCTGATATCTGCTACTCTACCCCT
GGCTGTGCTCACAGGACAGATATTTGCCCCCTTGTGATTATGACAGCAGACTGCAATAGTCTTC
TAGGTCATAGGTATCCCGGGCTCTTGTGTTGACCCTGGGGCTCGGGGATGAGTGTTTGCTGCTG
TGGGACATGATAAGCAATGGGTGCATCTCCAAATGGGTAAGAAGTCTCTGGGTAGAGTCCAGAT
CTTCTCCATTTTCCCCTCTCGGTGTCATAAGCAAGGGTACCCACCTCTGCCCACCCACGGCCTC
AACACACTCACGTCATAGTGATGGTCCTCGCACCATCCTCTTCCTATTCTTTGGGTAGGGTGAA
TGGACTCAGGGCTCACAATGAGAGAACAGCTAGGGCAGCCATTCTGGCCTGTATTCTGGAGCCT
ATGGGGAGTTTTCTAGGCAGGTCCATGCCATAGAGTGCAGTCCTGCCCATAGCCCTTCTCCCCC
CATACTGTAAATAATTTGTCATCATGGACTCCAACAGGGTCGGAGGGACAGATATAACCAATTG
AAATTCTCTGAAGATGCCATCTGTCTCCCGGGGTGCCAGCGCCTGCTATCATGTGCACCAAGTG
GCACTGGAGAGCCATAGAAGTCATAAGATACTGTATGTGTAAGCACATGTACATGAATGTGTGT
GTGTGTGTATGTGTGTGTGTAAGTGTGTGTGCGTGTGTGCACGAGTCTCATTCAGCCTCTGGGG
TCAAATCAGCTCCTCTCCTCTCCTCTACTCCTGGAGAGTAGTGACCATCAACATTTTCCCCTTC
TAGCTTCTATGTCTTGTTTTTGCTTTCCCTCCCCCCTCCTCCCCTCTCCTTCCTTCTCTCCTTC
TTTATTTGAGGGGGAAGAGTGCTGTACAAAGTCAAACAAACAAGTTTACAGTTGTAAGTGCAAT
GACCCGAGTCCTCCACATGACCTTGTGAATTGTGTGCCGTCCTCCTGTGCTCTGTGAGAACTCG
TGGTACTTCAGTGTCCCTCCCCTGTACTGTGACAAGGTATTTCTGTGGTATCAGAATAAAAGGA
CTTGATATAAACAAC

hide sequence

Protein Sequences


Protein RefSeqs	NP_062019	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA76287	(Get FASTA)	NCBI Sequence Viewer
	EDL77188	(Get FASTA)	NCBI Sequence Viewer
	EDL77189	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072024
GenBank Protein	O88778	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062019 ⟸ NM_019146

- UniProtKB:

O88778 (UniProtKB/Swiss-Prot), G3V984 (UniProtKB/TrEMBL), A6I338 (UniProtKB/TrEMBL), A0A0G2K1X6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGNEASLEGGAGEGPLPPGGSGLGPGPGAGKPPSALAGGGQLPVAGAARAAGPPTPGLGLVPGP
GPGPGPGSVSRRLDPKEPLGSQRATSPTPKQASATAPGRESPRETRAQGLSGQEAEGPRRTLQV
DSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQPNFNTCTQCHN
KVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLG
KPEQERSRSPGATQSGPRQAEAARATSVPGPTQATAPPEVGRVSPQPPLSTKPSTAEPRPPAGE
AQGKSATTVPSGLGAAEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGPPKIV
FSDASKEAGPRPPGSGPGPGPTPGAKTEPGPRTGPGSGPGALAKTGGTPSPKHGRADHQAASKA
AAKPKTMPKERAACPLCQAELNVGSRGPANYNTCTACKLRVCTLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPLPLPTPQQPPAGVPQRAAGASPLKQKGPQGPGQPSGSLPPKASPQAAKA
SPQAAKASPQAKPLRASEPSKTSSSAPEKKTGIPVKAEPVPKPPPETAVPPGTPKAKSGVKRTD
PATPVVKPVPEAPKSGEAEEPVPKPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVVQQEVEQ
LDSAGVTGPRPPSPSELHKVGSSMRPSLEAQAVAPSGEWSKPPSGSAVEDQKRRPHSLSIMPEA
FDSDEELGDILEEDDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAD
MTDEEFMRRQILEMSAEEDNLEEDDTAVSGRGLAKHGAQKASARPRPESSQESVALPKRRLPHN
ATTGYEELLSEEGPAEPTDGALQGGLRRFKTIELNSTGSYGHELDLGQGSDPNLDREPELEMES
LTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSH
GPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPP
SNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSEYNLPAF
MSLCSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAELLQRQQGQAAGARGPHGGPSQPTGPR
SQGSFEYQDTQDHDYGGRASQPAADGTPAGLGATVYEEILQTSQSIARMRQASSRDLAFTEDKK
KEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFPTSTSSDSSGGRVIPDVRVTQHFAKE
PQEPLKLHSSPASPSLASKEVGMTFSQGPGTPATTAMAPCPASLPRGYMTPAGPERSPSTSSTI
HSYGQPPTTANYGSQTEELPHAPSGPAGSGRASREKPLSGGDGEVGPPQPSRGYSYFTGSSPPL
SPSTPSESPTFSPSKLGPRATAEFSTQTPSLTPSSDIPRSPGTPSPMVAQGTQTPHRPSTPRLV
WQQSSQEAPVMVITLASDASSQTRMVHASASTSPLCSPTDSQPASHSYSQTTPPSASQMPSEPA
GPPGFPRAPSAGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKP
TPIILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSITM
ASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRGRPREAKFA
RYNLPNQVTPLARRDILITQMGTAQSVSLKPGPVPEPGAEPHRATPAELRAHALPGTRKPHTVV
VQMGEGAAGTVTTLLPEEPAGALDLTGMRPESRLACCDMAYKFPFGSSCTGTFHPAPSAPDKSV
TDAALPGQSSGPFYSPRDPEPPEPLTFRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEA
GLNYHAQRIGQLFQGPGRDSAVDLSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPL
PMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGGGSG
GPDLVPYQPQHGPGLNAPQGLASLRSGLLGNPTYPEGQPSPGNLAQYGPAASQGTAVRQLLPST
ATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYGSGGVTAVPLTSLTRVPMIA
PRVPLGPAGLYRYPAPSRFPIASTIPPAEGPVYLGKPAAAKASGAGGPPRPELPAGGAREEPLS
TTAPPAVIKEAPVAQAPAPPPGQKPAGDAAAGSGSGVLGRPVMEKEEASQEDRQRKQQEQLLQL
ERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFA
LQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPATCEAPSRGPPPAATELAQNGQYWP
PLTHTAFIAVAGTEGPGQAREPVLHRGLPSSASDMSLQTEEQWEAGRSGIKKRHSMPRLRDACE
PESGPDPSTVRRIADSSVQTDDEEGEGRYLLTRRRRTRRSADCSVQTDDEDNAEWEQPVRRRRS
RLSRHSDSGSDSKHEASASSSAAAAAARAMSSVGIQTISDCSVQTEPEQLPRVSPAIHITAATD
PKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFE
KKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVS
PQKQFIADSTLRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPN
GLVRKVKRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLV
EHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRVGRDYPPLRGLGEHRDYLSDS
ELNQLRLQGCTTPAGQYVDYPASAAVPATPSGPTAFQQPRFPPAATQYTAGSSGPTQNGFLAHQ
APTYTGPSTYPAPTYPPGTSYPAEPGLPSQPAFHPTGHYAAPTPMPTTQSAPFPVQADSHAAHQ
KPRQTSLADLEQKVPTNYEVISSPAVTVSSTPSETGYSGPAVSSSYEHGKAPEHPRGGDRSSVS
QSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTPTASDSQRPEPLGPGGVSGRPGKDPG
EPAVLEGPTLPCCYGRGEEESEEDSYDPRGKSGHHRSMESNGRPASTHYYSDSDYRHGARADKY
GPGPMGPKHPSKNLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLT
SRSRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSRSRVASAYSGEKLSSHDFSS
RSKGYERERETAERLQKAGPKPSSLSMAHGRARPPMRSQASEEESPVSPLGRPRPAGGALPPGD
TCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDA
RSDRFRHHGGHTVSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRHHGDHGRHS
GRHAGEEPGRRAARPHARDMGRHETRPHPQASPAPAMQKKGQPGYPSSADYSQPSRAPSAYHHA
SDSKKGSRQAHSGPTVLQPKPEAQAQPQMQGRQAVPGPQQSQPPSSRQTPSGTASRQPQTQQQQ
QQQQQQQQQQQQQQQQGLGQQAPQQAPSQARLQQQSQPTTRSTAPAASHPAGKPQPGPTTAPGP
QPAGLPRAEQAGSSKPAAKAPQQGRAPQAQSAPGPAGAKTGARPGGTPGAPAGQPAAEGESVFS
KILPGGAAEQAGKLTEAVSAFGKKFSSFW

hide sequence

Ensembl Acc Id:

ENSRNOP00000072024 ⟸ ENSRNOT00000082113

Ensembl Acc Id:

ENSRNOP00000039162 ⟸ ENSRNOT00000042528

Protein Domains

Zinc finger piccolo-type

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696291

Promoter ID:

EPDNEW_R6816

Type:

single initiation site

Name:

Bsn_1

Description:

bassoon

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	116,965,404 - 116,965,464	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2223	AgrOrtholog
BioCyc Gene	G2FUF-29156	BioCyc
Ensembl Genes	ENSRNOG00000030714	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000082113	ENTREZGENE
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot
InterPro	Bsn	UniProtKB/Swiss-Prot
	Presynaptic_Scaffold_Bsn/Pclo	UniProtKB/Swiss-Prot
	Znf_FYVE_PHD	UniProtKB/Swiss-Prot
	Znf_piccolo	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot
NCBI Gene	29138	ENTREZGENE
PANTHER	PICCOLO/BASSOON	UniProtKB/Swiss-Prot
	PTHR14113:SF1	UniProtKB/Swiss-Prot
Pfam	zf-piccolo	UniProtKB/Swiss-Prot
PhenoGen	Bsn	PhenoGen
RatGTEx	ENSRNOG00000030714	RatGTEx
Superfamily-SCOP	SSF57903	UniProtKB/Swiss-Prot
UniProt	A0A0G2K1X6	ENTREZGENE, UniProtKB/TrEMBL
	A6I338	ENTREZGENE, UniProtKB/TrEMBL
	BSN_RAT	UniProtKB/Swiss-Prot
	G3V984	ENTREZGENE
	O88778	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-01-14	Bsn	bassoon (presynaptic cytomatrix protein)	Bsn	bassoon	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Bsn	bassoon			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to the axon terminals of hippocampal neurons	69780
gene_cellular_localization	presynaptic cytomatrix protein	69780
gene_domains	contains two double-zinc fingers, several coiled-coil domains, and a stretch of polyglutamines	69780

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI