Activ1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Activ1 (Activity QTL 1) Rattus norvegicus

Symbol: Activ1
Name: Activity QTL 1
RGD ID: 631217
Previously known as: Ma1; Motor activity QTL 1; Act1
Trait: voluntary movement trait   (VT:0003491)    
Measurement Type: number of photobeam interruptions in an experimental apparatus   (CMO:0001517)    
LOD Score: 15.9
P Value: Not Available
Variance: 35.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28102,370,617 - 108,923,645RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.08110,212,979 - 116,947,981RGD_MAPPER_PIPELINERnor6.0
Rnor_5.08109,621,234 - 116,312,980RGDRnor5.0
RGSC_v3.48106,733,287 - 113,364,148RGDRGSC3.4
RGSC_v3.18106,752,743 - 113,498,899RGD
Cross Type: intercross
Strains Crossed: WKY WKHA/N 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Hyperkinesis  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Vertebrate Trait

Rat Strain
WKHA/N  (IEA)
WKY  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Ahmadiyeh N, etal., Behav Genet 2005 Mar;35(2):189-98.
2. Further dissection of a genomic locus associated with behavioral activity in the Wistar-Kyoto hyperactive rat, an animal model of hyperkinesis. Moisan MP, etal., Mol Psychiatry 2003 Mar;8(3):348-52.
3. A major quantitative trait locus influences hyperactivity in the WKHA rat. Moisan MP, etal., Nat Genet 1996 Dec;14(4):471-3.
Related QTLs

Related QTL Description Reference
Stresp11 maps to same region RGD:1358767
Activ2 maps to same region RGD:631228


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2556Ephb1Eph receptor B18102507549102944839Rat
1305407Kykyphoscoliosis peptidase8103086959103126305Rat
41111708Rpl27-ps3ribosomal protein L27, pseudogene 38103138302103138924Rat
1561183Cep63centrosomal protein 638103162639103214177Rat
1583270Anapc13anaphase promoting complex subunit 138103205520103213936Rat
70977Amotl2angiomotin like 28103303368103319161Rat
620549Rykreceptor-like tyrosine kinase8103419338103492083Rat
7621358LOC102549824uncharacterized LOC1025498248103578910103588660Rat
3051Slco2a1solute carrier organic anion transporter family, member 2a18103588916103672546Rat
41348082LOC120094519small nucleolar RNA SNORA178103607316103607440Rat
1309958Rab6bRAB6B, member RAS oncogene family8103695328103764023Rat
1304698SrprbSRP receptor subunit beta8103768685103782632Rat
3845Tftransferrin8103789780103816487Rat
41361285LOC120094247uncharacterized LOC1200942478103826885103829663Rat
1310507Inhcainhibitor of carbonic anhydrase8103836846103874980Rat
1562949Topbp1DNA topoisomerase II binding protein 18103887805103931662Rat
1359113Cdv3carnitine deficiency-associated gene expressed in ventricle 38103934006103947173Rat
7532272LOC102550226uncharacterized LOC1025502268103967818103978728Rat
1591927Bfsp2beaded filament structural protein 28104006226104063399Rat
1311530Tmem108transmembrane protein 1088104066081104360172Rat
41062204Smarce1-ps7SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, pseudogene 78104258115104259349Rat
7512575LOC102550471uncharacterized LOC1025504718104397919104405607Rat
1591994Rpl27-ps1ribosomal protein L27, pseudogene 18104497134104497579Rat
41111408LOC120094250uncharacterized LOC1200942508104557812104583967Rat
1563856Nphp3nephrocystin 38104621908104662383Rat
1311702Uba5ubiquitin-like modifier activating enzyme 58104665241104680915Rat
1306270Acad11acyl-CoA dehydrogenase family, member 118104681346104746559Rat
1596453Ackr4atypical chemokine receptor 48104716537104720972Rat
41233547LOC120094252uncharacterized LOC1200942528104757449104772885Rat
1308046Dnajc13DnaJ heat shock protein family (Hsp40) member C138104767785104877317Rat
2023Acp3acid phosphatase 38104905570104956146Rat
41393413Rps6-ps7ribosomal protein S6, pseudogene 78104961099104961924Rat
11503015Trnac-gca31transfer RNA cysteine (anticodon GCA) 318105020043105020114Rat
11439069Trnac-gca32transfer RNA cysteine (anticodon GCA) 328105023468105023539Rat
11519997Trnae-uuc4transfer RNA glutamic acid (anticodon UUC) 48105028879105028950Rat
40980385LOC120094513small nucleolar RNA SNORA178105100538105100654Rat
1591993Rps11-ps16ribosomal protein S11, pseudogene 168105114531105115646Rat
1308844Cpne4copine 48105177376105653075Rat
1306391Mrpl3mitochondrial ribosomal protein L38105670184105693544Rat
1311387Nudt16nudix hydrolase 168105739927105741982Rat
1584138Nudt16l2nudix hydrolase 16 like 28105754821105756548Rat
1308801Nek11NIMA-related kinase 118105767230106026676Rat
7489031Mir6330microRNA 63308105784904105785042Rat
7577342Sms-ps1spermine synthase, pseudogene 18105964464105968641Rat
1304643Aste1asteroid homolog 18106026570106044694Rat
621311Atp2c1ATPase secretory pathway Ca2+ transporting 18106034777106155854Rat
7604621Apex2-ps1apurinic/apyrimidinic endodeoxyribonuclease 2, pseudogene 18106072038106074709Rat
1560844Rpl29-ps14ribosomal protein L29, pseudogene 148106177818106178267Rat
41341470LOC1200944005S ribosomal RNA8106210563106210681Rat
1311809Pik3r4phosphoinositide-3-kinase, regulatory subunit 48106267908106316585Rat
1309172Col6a6collagen type VI alpha 6 chain8106318010106473419Rat
9338792LOC103693167uncharacterized LOC1036931678106473549106501011Rat
1565804Col6a5collagen type VI alpha 5 chain8106483806106584114Rat
41037238Trnal-aag7transfer RNA leucine (anticodon AAG) 78106522331106522405Rat
1564060Col6a4collagen, type VI, alpha 48106617169106733493Rat
41380564Rpl6-ps10ribosomal protein L6, pseudogene 108106759114106761529Rat
1591498Glyctkglycerate kinase8106795461106802675Rat
1584269Wdr82WD repeat domain 828106814569106834535Rat
9685094Mirlet7gmicroRNA let-7g8106822293106822380Rat
1584266Ppm1mprotein phosphatase, Mg2+/Mn2+ dependent, 1M8106836221106843472Rat
1591460Twf2twinfilin actin-binding protein 28106845253106858298Rat
631352Tlr9toll-like receptor 98106864680106868796Rat
68392Alas15'-aminolevulinate synthase 18106876514106889917Rat
1565004Poc1aPOC1 centriolar protein A8106922058106991678Rat
40974940LOC120094254uncharacterized LOC1200942548106952559106969689Rat
735026Dusp7dual specificity phosphatase 78107009369107016404Rat
62069Rpl29ribosomal protein L298107068929107070963Rat
2030Acy1aminoacylase 18107072354107077756Rat
1309721Abhd14aabhydrolase domain containing 14A8107079139107089004Rat
1359649Abhd14babhydrolase domain containing 14b8107087157107092122Rat
1307910Pcbp4poly(rC) binding protein 48107092688107103276Rat
1560166Gpr62G protein-coupled receptor 628107103225107105311Rat
1305189Parp3poly (ADP-ribose) polymerase family, member 38107111010107117073Rat
1307881Rrp9ribosomal RNA processing 9, U3 small nucleolar RNA binding protein8107116411107126123Rat
1565640Iqcf1IQ motif containing F18107129462107133242Rat
1560754Iqcf5IQ motif containing F58107151477107152862Rat
1565277Iqcf3IQ motif containing F38107163067107198028Rat
7631233LOC102550160IQ domain-containing protein F5-like8107206402107208677Rat
1562645Iqcf6IQ motif containing F68107263673107264726Rat
40978404Trnas-aga34transfer RNA serine (anticodon AGA) 348107275614107275688Rat
2743Grm2glutamate metabotropic receptor 28107280099107293159Rat
1359353Tex264testis expressed 2648107295806107322858Rat
1561889Rad54l2RAD54 like 28107324945107427033Rat
1593469Timm8a1-ps1translocase of inner mitochondrial membrane 8A1, pseudogene 18107440411107448210Rat
1305176Dcaf1DDB1 and CUL4 associated factor 18107466229107540633Rat
1307252Manfmesencephalic astrocyte-derived neurotrophic factor8107500856107551595Rat
1305937Rbm15bRNA binding motif protein 15B8107543613107546678Rat
1306677Dock3dedicator of cyto-kinesis 38107552462107903527Rat
41314406LOC120094488small nucleolar RNA SNORA178107838468107838598Rat
7507784Blmh-ps1bleomycin hydrolase, pseudogene 18107847016107857956Rat
1304980Mapkapk3MAPK activated protein kinase 38107929754107963638Rat
41391883Rpsa-ps9ribosomal protein SA, pseudogene 98107966999107970488Rat
69261Cishcytokine inducible SH2-containing protein8107972306107977254Rat
1308293Hemk1HemK methyltransferase family member 18107999658108010732Rat
1307461C8h3orf18similar to human chromosome 3 open reading frame 188108012638108022050Rat
631360Cacna2d2calcium voltage-gated channel auxiliary subunit alpha2delta 28108072208108203516Rat
41184370LOC120094259uncharacterized LOC1200942598108184284108207504Rat
1310540Tmem115transmembrane protein 1158108207463108212327Rat
1359644Cyb561d2cytochrome b561 family, member D28108213201108215778Rat
1308927Nprl2NPR2-like, GATOR1 complex subunit8108215823108218996Rat
1303250Zmynd10zinc finger, MYND-type containing 108108220386108224745Rat
1359383Rassf1Ras association domain family member 18108225023108236164Rat
1561664Tusc2tumor suppressor 2, mitochondrial calcium regulator8108236838108240056Rat
620321Hyal2hyaluronidase 28108241895108246853Rat
1303060Hyal1hyaluronidase 18108250668108254519Rat
6496422Naa80N(alpha)-acetyltransferase 80, NatH catalytic subunit8108254314108257564Rat
1303334Hyal3hyaluronidase 38108254385108260020Rat
1310222Ifrd2interferon-related developmental regulator 28108260969108266191Rat
1589957Lsmem2leucine-rich single-pass membrane protein 28108265855108270656Rat
1310079Sema3bsemaphorin 3B8108271663108280326Rat
41293752LOC120094260uncharacterized LOC1200942608108280472108288983Rat
620243Gnai2G protein subunit alpha i28108288401108309009Rat
628620Slc38a3solute carrier family 38, member 38108323889108339959Rat
1304683Gnat1G protein subunit alpha transducin 18108350935108355671Rat
1308514Sema3fsemaphorin 3F8108357629108386569Rat
1305059Rbm5RNA binding motif protein 58108420220108449481Rat
1560367Rbm6RNA binding motif protein 68108452687108552783Rat
1588858Cfl1l1cofilin 1 like 18108489949108491597Rat
7535217Eno1-ps23enolase 1, pseudogene 238108499236108500742Rat
40983521Trnap-agg36transfer RNA proline (anticodon AGG) 368108555963108556043Rat
1308823Mon1aMON1 homolog A, secretory trafficking associated8108574272108593163Rat
1306465Mst1rmacrophage stimulating 1 receptor8108596100108611441Rat
1310036Actl11actin-like 118108619143108622836Rat
621488CamkvCaM kinase-like vesicle-associated8108626821108641169Rat
1309761TraipTRAF-interacting protein8108641860108661640Rat
1308323Uba7ubiquitin-like modifier activating enzyme 78108665289108674097Rat
1560778Inka1inka box actin regulator 18108674263108675953Rat
1306603Cdhr4cadherin-related family member 48108682594108690358Rat
71025Ip6k1inositol hexakisphosphate kinase 18108693068108737278Rat
1560458GmppbGDP-mannose pyrophosphorylase B8108737429108740437Rat
2301394Rnf123ring finger protein 1238108740176108768177Rat
631413Amigo3adhesion molecule with Ig like domain 38108741899108743425Rat
3114Mst1macrophage stimulating 18108767886108773425Rat
2125Apehacylaminoacyl-peptide hydrolase8108773791108782903Rat
2223Bsnbassoon (presynaptic cytomatrix protein)8108784849108875819Rat
621890Dag1dystroglycan 18108890926108955611Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10074D8Wox158104917506104917671Ratregion
33919D8Mit151008102370617102370718Ratregion
34062D8Mgh22428105647037105647297Ratregion
34068D8Mgh111508105647049105647213Ratregion
35405D8Rat601628104790881104791045Ratregion
35537D8Rat122048104215934104216130Ratregion
37130D8Rat1071888103897218103897433Ratregion
37736D8Rat652398105406630105406857Ratregion
34949D8Rat131678102387671102387838Ratregion
40480D8Rat1751258103687536103687659Ratregion
40308D8Rat1671758102620359102620533Ratregion
38956D8Rat672128108836661108836849Ratregion
39134D8Rat762238107269825107270051Ratregion
39328D8Rat1032448106538675106538907Ratregion
42230D8Arb182628103671211103671496Ratregion
42232D8Arb192218107183772107183995Ratregion
42234D8Arb203938108776825108777230Ratregion
42240D8Arb28608105495002105495062Ratregion
41082D8Rat1232108104073095104073311Ratregion
44510D8Got1611568102866210102866364Ratregion
44511D8Got1681588104419802104419960Ratregion
44512D8Got1661798105366332105366513Ratregion
44513D8Got1641568104380921104381077Ratregion
44514D8Got1741968108488184108488380Ratregion
44515D8Got1632488105082174105082423Ratregion
44516D8Got1752368107779518107779754Ratregion
44517D8Got1721468108535894108536039Ratregion
44518D8Wox71948108776880108777075Ratregion
44519D8Got2072048106679470106679674Ratregion
44521D8Got1692368107269796107270033Ratregion
44522D8Got1702978103896990103897441Ratregion
44522D8Got1702978103897143103897441Ratregion
44523D8Got1732518107680423107680674Ratregion
60603D8Got1711848106086869106087053Ratregion
60604D8Got1761508108572029108572179Ratregion
60605D8Got1771338108599874108600112Ratregion
60605D8Got1771338108599979108600112Ratregion
66496D8Uia41638107500218107500385Ratregion
66498D8Uia51328107500239107500375Ratregion
1630518D8Got3171728102806200102806372Ratregion
1631834D8Got330868105915667105915753Ratregion
1579050D10Chm1742398108680723108681193Ratregion
1629375D8Wox191838107268671107268852Ratregion
1629821D8Wox142398107183758107183999Ratregion
1641618D8Got311858106180570106180652Ratregion
1640120D8Wox322618108793202108793463Ratregion
1633936D8Got3411438104539991104540136Ratregion
1634519D8Got1621168103157666103157779Ratregion
1634864D8Wox258103671212103671431Ratregion
7192145Cfl11748108490519108490693Ratregion
7191291D8Wox111598108784680108784789Ratregion
5038686C794671218107540327107540448Ratregion
5036249D9Mgc281908104368493104368683Ratregion
5036257Dag12468108894531108894777Ratregion
5036687AU0488781778105092255105092434Ratregion
5037069WI-187241298108452708108452837Ratregion
5031216SGC320041268103319009103319135Ratregion
5025958RH1303522048107079168107079372Ratregion
5031512AU0480812648104340749104341013Ratregion
5031652AU0475982668108516269108516535Ratregion
5031826AU0470261348102419307102419441Ratregion
5026474RH1323481808106318292106318472Ratregion
5032125RH944621008108773819108773919Ratregion
5032161RH1259712158108288987108289202Ratregion
5026880RH1338822028103124626103124828Ratregion
5032291AV0064031268106036772106036898Ratregion
5026980RH1342671828103763734103763916Ratregion
5026988RH1342971808108504383108504563Ratregion
5034670BF3909361518103167280103167431Ratregion
5032747RH1351512148104169204104169418Ratregion
5025062RH1265432278103767973103768200Ratregion
5027679242D11L22738104078275104078523Ratregion
5030341BF4027471918105652539105652730Ratregion
5033345RH1384912458107847610107847855Ratregion
5025446RH1283481848107929828107930012Ratregion
5033483RH1389971408107546829107546969Ratregion
5030739BE1078411748107971875107972049Ratregion
5033519RH1391261848108254313108254497Ratregion
5056149RH1442121688107329484107329652Ratregion
5057540BE0955081598104317729104317888Ratregion
5059680BE0976101928108790188108790380Ratregion
5052225D179141538107548389107548542Ratregion
5055289RH1437151438107008675107008818Ratregion
5052585RH1257152418108239798108240039Ratregion
5059902BF3881952118105689451105689662Ratregion
5049864RH1337261848108365267108365451Ratregion
5052303R747261938104067695104067888Ratregion
5059136BF3875001578108786414108786571Ratregion
5059186BF3876011748108253956108254130Ratregion
5059372AW5304631978107508795107508992Ratregion
5057602BI2832531168104917129104917247Ratregion
5052587RH1257171468107548388107548534Ratregion
5054249RH1431161748106257299106257559Ratregion
5051481AU017982908108687636108687726Ratregion
5054783RH1434231408103305467103305607Ratregion
5050812RH1342721978107083117107083314Ratregion
5044502RH1306402108104665380104665590Ratregion
5044560RH1306742058106074430106074635Ratregion
5045520RH1312251938103931353103931546Ratregion
5045592RH1312661838106043610106043793Ratregion
5041486RH1288842168108212070108212286Ratregion
5045792RH1313812178107072527107072971Ratregion
5045828RH1314021848103126047103126231Ratregion
5047726RH1324931838106837185106837368Ratregion
5048860RH1331481838107015044107016278Ratregion
5048932RH1331891878106049199106049386Ratregion
5046702RH1319062068108271751108271957Ratregion
5048208RH1327702168108218744108218960Ratregion
5039514RH1277491858108736738108736923Ratregion
5047368RH1322871958104507097104507288Ratregion
5039734RH1278762068108239617108239823Ratregion
5042280RH1293431858103225914103226099Ratregion
5039568RH1277802208107091707107091927Ratregion
5042058RH1292141508107548385107548535Ratregion
5042994RH1297681768108744055108744231Ratregion
5043512RH1300671818106795501106795682Ratregion
5072680RH1369901808108224544108224724Ratregion
5072722RH1370152078108350968108351175Ratregion
5072762RH1370381848108661428108661612Ratregion
5079484RH1410241868108323996108324182Ratregion
5077154RH1395931858108741840108742025Ratregion
5079774RH1411952118106316358106316569Ratregion
5079860RH1412451878103672776103672963Ratregion
5078960RH1406522168108738658108739067Ratregion
5080156RH1414172028108229210108229412Ratregion
5078480RH1403671768108213331108213507Ratregion
5079172RH1407771818108288979108289160Ratregion
5079266RH1408821848105693041105693225Ratregion
5073202RH1372991878103491046103491233Ratregion
5071602RH1351772178108892138108892355Ratregion
5074428RH1380111838107573552107573735Ratregion
5074514RH1380611518102508066102508217Ratregion
5073494RH1374691838106799416106799599Ratregion
5074680RH1381561348107541257107541391Ratregion
5067646AU0476201708104322659104322829Ratregion
5068616AU0470372108107082514107082558Ratregion
5070372AI838527848108265918108266002Ratregion
5070460AI8746651248107929959107930083Ratregion
5060200AI1448001078107552421107552528Ratregion
5060252BG3781401188108894377108894495Ratregion
5063752AW5350671518102507590102507741Ratregion
5063792AW5351821518106146190106146341Ratregion
5064082BE1140101688106069078106069246Ratregion
5064142BE1206561828103936881103937403Ratregion
5064284BE1209851918103782833103783024Ratregion
5066018BE1165571508107599289107599439Ratregion
5062380BF3978662288106802597106802825Ratregion
5062502BE1067741908107186160107186350Ratregion
5065982BE1163911918103491524103491715Ratregion
5066168BF4071051268108266299108266425Ratregion
5066250PMC126259P2818108640093108640174Ratregion
5066556AU0482871528105563021105563173Ratregion
5061582BF3967421408108215977108216530Ratregion
5087820D9Mgc44e1798103125062103125241Ratregion
5087822D9Mgc48e818103171580103171661Ratregion
5087824RH1256951588108891055108891213Ratregion
5082779BF3900841538106034833106034986Ratregion
5082889BF3903361888103767150103767337Ratregion
5087420Ephb12378102508639102508876Ratregion
5088128Trf2198103816628103816847Ratregion
5088599AU0486652018107779524107779725Ratregion
5088681AU0487131348102546895102547029Ratregion
5083952AI0120391158103162846103162961Ratregion
5081819BI2737691898108288701108288891Ratregion
5081945BE1188011828108619729108619911Ratregion
5087818D9Mgc291328104497554104497686Ratregion
5082455BE1194471558108742655108742810Ratregion
5090859AU0500082558107680423107680679Ratregion
5080826RH1418051818103761457103761638Ratregion
5088729AU0487441048103702413103702517Ratregion
5089253AU0490461168105017510105017626Ratregion
5081286RH1420731948108271226108271420Ratregion
5083161BI2752242448107108605107108849Ratregion
5086620BQ2057141888104719597104719785Ratregion
5503388SSC24F051608108892012108892172Ratregion
5504694PMC55404P12608106868367106868627Ratregion
5504350D11S383108106679515106680656Ratregion
5506306D3S45202738108360547108360820Ratregion
5506308D3S45196148108360799108361413Ratregion
5500025UniSTS:2362461568108246387108246543Ratregion
5501057PMC133006P33198106868325106868644Ratregion
5500356GDB:30460408103993959103994406Ratregion
5501227PMC156147P151598107972039107972198Ratregion
5501225PMC156147P142528107971848107972100Ratregion
5501255PMC17675P15358108352589108353124Ratregion
5505153Amigo39928108742329108743321Ratregion
5501910MARC_17265-17266:1024683815:11188108758229108758740Ratregion
5502110MARC_4375-4376:966894539:12008104259008104259208Ratregion
5502505RH1251211438103763855103763998Ratregion
Position Markers

Flank 1: (D8Mit15)
Rat AssemblyChrPosition (strand)Source
mRatBN7.28102,370,617 - 102,370,718 (+)MAPPER
Rnor_6.08110,212,979 - 110,213,079NCBI
Rnor_5.08109,621,234 - 109,621,334UniSTS
RGSC_v3.48106,733,287 - 106,733,388RGD
RGSC_v3.48106,733,288 - 106,733,388UniSTS
RGSC_v3.18106,752,743 - 106,752,843RGD
Celera8101,755,196 - 101,755,296UniSTS
RH 3.4 Map81170.9UniSTS
RH 3.4 Map81170.9RGD
RH 2.0 Map8858.6RGD
Peak: (D8Mgh11)
Rat AssemblyChrPosition (strand)Source
mRatBN7.28105,647,049 - 105,647,213 (+)MAPPER
Rnor_6.08113,580,399 - 113,580,562NCBI
Rnor_5.08112,967,026 - 112,967,189UniSTS
RGSC_v3.48110,106,284 - 110,106,448RGD
RGSC_v3.48110,106,285 - 110,106,448UniSTS
RGSC_v3.18110,125,739 - 110,125,903RGD
Celera8105,003,697 - 105,003,860UniSTS
RH 3.4 Map81145.3UniSTS
RH 3.4 Map81145.3RGD
RH 2.0 Map8871.2RGD
Cytogenetic Map8q32UniSTS
Flank 2: (D8Wox11)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.48113,364,040 - 113,364,148UniSTS
Celera8108,088,893 - 108,089,001UniSTS
RH 3.4 Map81120.8UniSTS
RH 3.4 Map81120.8RGD
RH 2.0 Map8873.1RGD
Cytogenetic Map8q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Activ1


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 Activ1  Activity QTL 1  Act1    Symbol updated 1299863 APPROVED
2003-10-17 Act1  Activity QTL 1  Ma1  Motor activity QTL 1  Symbol and Name updated 632217 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_disease model for hyperactivity 631170
qtl_gene D8Rat44 was used for linkage analysis with D2 dopamine receptor gene 631228
qtl_general also shows significance for rearings in an open field (lod=~6.4) and spontaneous activity (lod=4.4) 631170
qtl_general has strong influence on the hyperactivity phenotypes that are related to motor activity 631170
qtl_general highest LOD was observed for ambulatory activity at age 8 and 16 weeks over an hour period in activity cages which narrowed this QTL to approximately 10 cM 631228
qtl_general this QTL is weak in exploratory activity and not for ambulatory activity in the BNxWKHA cross as compared to the WKYxWKHA cross 631228