Nup214 (nucleoporin 214) - Rat Genome Database

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Pathways
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Gene: Nup214 (nucleoporin 214) Rattus norvegicus
Analyze
Symbol: Nup214
Name: nucleoporin 214
RGD ID: 1304977
Description: Enables nuclear localization sequence binding activity. Predicted to be involved in regulation of nucleocytoplasmic transport. Predicted to act upstream of or within nucleocytoplasmic transport and regulation of cell cycle. Located in nuclear envelope. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Orthologous to human NUP214 (nucleoporin 214); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mRNA nuclear export pathway; NXF1-NXT1 export pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diethylstilbestrol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296634; nuclear pore complex protein Nup214; nucleoporin 214kDa; RGD1304977; similar to mKIAA0023 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8335,652,841 - 35,738,323 (+)NCBIGRCr8
mRatBN7.2315,255,111 - 15,340,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,255,119 - 15,340,568 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,328,071 - 18,410,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0326,913,061 - 26,995,162 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,160,272 - 25,245,882 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.039,227,869 - 9,236,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0310,993,584 - 11,070,638 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl39,227,823 - 9,236,736 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl310,999,186 - 11,070,640 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,351,780 - 16,423,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0314,588,337 - 14,597,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,079,165 - 11,165,173 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1310,975,349 - 11,062,057 (+)NCBI
Celera310,002,669 - 10,087,697 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex. Bastos R, etal., J Cell Biol 1997 Jun 2;137(5):989-1000.
2. Sequential recruitment of NPC proteins to the nuclear periphery at the end of mitosis. Bodoor K, etal., J Cell Sci. 1999 Jul;112 ( Pt 13):2253-64.
3. Regulation of mRNA trafficking by nuclear pore complexes. Bonnet A and Palancade B, Genes (Basel). 2014 Sep 2;5(3):767-91. doi: 10.3390/genes5030767.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Radu A, etal., Proc Natl Acad Sci U S A 1995 Feb 28;92(5):1769-73.
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Nuclear export and cytoplasmic maturation of ribosomal subunits. Zemp I and Kutay U, FEBS Lett. 2007 Jun 19;581(15):2783-93. Epub 2007 May 11.
Additional References at PubMed
PMID:8108440   PMID:8896451   PMID:10358091   PMID:10557333   PMID:11000203   PMID:12191473  


Genomics

Comparative Map Data
Nup214
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8335,652,841 - 35,738,323 (+)NCBIGRCr8
mRatBN7.2315,255,111 - 15,340,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,255,119 - 15,340,568 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,328,071 - 18,410,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0326,913,061 - 26,995,162 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,160,272 - 25,245,882 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.039,227,869 - 9,236,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0310,993,584 - 11,070,638 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl39,227,823 - 9,236,736 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl310,999,186 - 11,070,640 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,351,780 - 16,423,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0314,588,337 - 14,597,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,079,165 - 11,165,173 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1310,975,349 - 11,062,057 (+)NCBI
Celera310,002,669 - 10,087,697 (+)NCBICelera
Cytogenetic Map3p12NCBI
NUP214
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389131,125,586 - 131,234,663 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9131,125,573 - 131,234,663 (+)EnsemblGRCh38hg38GRCh38
GRCh379134,000,973 - 134,110,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369132,990,802 - 133,098,912 (+)NCBINCBI36Build 36hg18NCBI36
Build 349131,030,534 - 131,138,644NCBI
Celera9104,540,049 - 104,648,175 (+)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9103,491,679 - 103,601,026 (+)NCBIHuRef
CHM1_19134,150,562 - 134,259,670 (+)NCBICHM1_1
T2T-CHM13v2.09143,333,818 - 143,442,978 (+)NCBIT2T-CHM13v2.0
Nup214
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39231,864,446 - 31,943,204 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl231,864,448 - 31,943,987 (+)EnsemblGRCm39 Ensembl
GRCm38231,974,408 - 32,053,975 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl231,974,436 - 32,053,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37231,829,970 - 31,909,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36231,796,448 - 31,875,984 (+)NCBIMGSCv36mm8
Celera231,677,520 - 31,757,311 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.97NCBI
Nup214
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955513955,639 - 1,038,912 (+)NCBIChiLan1.0ChiLan1.0
NUP214
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2118,117,336 - 8,227,218 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan198,119,678 - 8,229,571 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09102,246,575 - 102,355,291 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19130,893,110 - 131,001,305 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9130,893,110 - 131,001,305 (+)Ensemblpanpan1.1panPan2
NUP214
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1952,840,300 - 52,943,785 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl952,841,096 - 52,947,770 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha952,105,504 - 52,144,484 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0953,741,391 - 53,844,849 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl953,741,391 - 53,844,989 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1952,518,914 - 52,622,350 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0952,839,417 - 52,942,849 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0952,932,424 - 53,035,905 (-)NCBIUU_Cfam_GSD_1.0
Nup214
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947198,212,850 - 198,299,295 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648717,981,304 - 18,067,854 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648717,981,402 - 18,067,828 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP214
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1271,104,033 - 271,210,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11271,103,838 - 271,210,292 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21305,130,794 - 305,237,538 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUP214
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1126,905,047 - 7,014,907 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl126,903,096 - 7,014,887 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660798,486,610 - 8,597,948 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup214
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247604,655,247 - 4,739,298 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247604,655,347 - 4,738,811 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nup214
439 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:112
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000037164, ENSRNOT00000072628
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat

Markers in Region
D3Rat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,337,931 - 15,338,131 (+)MAPPERmRatBN7.2
Rnor_6.0311,068,002 - 11,068,201NCBIRnor6.0
Rnor_5.0316,420,596 - 16,420,795UniSTSRnor5.0
RGSC_v3.4311,162,537 - 11,162,736UniSTSRGSC3.4
RGSC_v3.4311,162,536 - 11,162,736RGDRGSC3.4
RGSC_v3.1311,058,909 - 11,059,108RGD
Celera310,085,061 - 10,085,260UniSTS
RH 3.4 Map363.0RGD
RH 3.4 Map363.0UniSTS
RH 2.0 Map30.0RGD
SHRSP x BN Map33.4899RGD
FHH x ACI Map34.78RGD
Cytogenetic Map3p11UniSTS
AI013738  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,253,581 - 15,253,676 (-)MAPPERmRatBN7.2
Rnor_6.039,238,301 - 9,238,395NCBIRnor6.0
Rnor_5.0314,598,618 - 14,598,712UniSTSRnor5.0
RGSC_v3.4311,077,628 - 11,077,722UniSTSRGSC3.4
Celera310,001,132 - 10,001,226UniSTS
RH 3.4 Map359.0UniSTS
Cytogenetic Map3p11UniSTS
BF386249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,261,188 - 15,261,354 (-)MAPPERmRatBN7.2
Rnor_6.039,230,624 - 9,230,789NCBIRnor6.0
Rnor_5.0314,590,941 - 14,591,106UniSTSRnor5.0
RGSC_v3.4311,085,234 - 11,085,399UniSTSRGSC3.4
Celera310,008,738 - 10,008,903UniSTS
RH 3.4 Map359.0UniSTS
Cytogenetic Map3p11UniSTS
BE115511  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,320,600 - 15,320,813 (+)MAPPERmRatBN7.2
Rnor_6.0311,050,671 - 11,050,883NCBIRnor6.0
Rnor_5.0316,403,265 - 16,403,477UniSTSRnor5.0
RGSC_v3.4311,145,206 - 11,145,418UniSTSRGSC3.4
Celera310,067,730 - 10,067,942UniSTS
RH 3.4 Map362.0UniSTS
Cytogenetic Map3p11UniSTS
AU046699  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,293,652 - 15,293,845 (+)MAPPERmRatBN7.2
Rnor_6.0311,023,724 - 11,023,916NCBIRnor6.0
Rnor_5.0316,376,318 - 16,376,510UniSTSRnor5.0
RGSC_v3.4311,118,259 - 11,118,451UniSTSRGSC3.4
Celera310,040,780 - 10,040,972UniSTS
Cytogenetic Map3p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 49 55 24 38 24 1 1 130 58 75 22 1
Low 1 29 53 52 52 15 20 8 10 15
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000037164   ⟹   ENSRNOP00000033579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,255,119 - 15,340,568 (+)Ensembl
Rnor_6.0 Ensembl310,999,186 - 11,070,636 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072628   ⟹   ENSRNOP00000067057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,256,213 - 15,264,103 (+)Ensembl
Rnor_6.0 Ensembl39,227,823 - 9,236,736 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl311,011,768 - 11,013,901 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl311,070,066 - 11,070,640 (+)Ensembl
RefSeq Acc Id: NM_001168559   ⟹   NP_001162031
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,652,879 - 35,738,323 (+)NCBI
mRatBN7.2315,255,119 - 15,340,568 (+)NCBI
Rnor_6.0310,993,584 - 11,070,638 (+)NCBI
Rnor_5.0314,588,337 - 14,597,175 (-)NCBI
Rnor_5.0316,351,780 - 16,423,232 (+)NCBI
RGSC_v3.4311,079,165 - 11,165,173 (+)RGD
Celera310,002,669 - 10,087,697 (+)RGD
Sequence:
RefSeq Acc Id: XM_039104750   ⟹   XP_038960678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,652,841 - 35,738,323 (+)NCBI
mRatBN7.2315,255,111 - 15,340,568 (+)NCBI
RefSeq Acc Id: XM_039104751   ⟹   XP_038960679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,652,841 - 35,738,323 (+)NCBI
mRatBN7.2315,255,111 - 15,340,568 (+)NCBI
RefSeq Acc Id: XM_039104752   ⟹   XP_038960680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,652,841 - 35,738,323 (+)NCBI
mRatBN7.2315,255,111 - 15,340,568 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001162031 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960678 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960679 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960680 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93258 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033579
  ENSRNOP00000033579.6
  ENSRNOP00000067057.3
Reference Protein Sequences
RefSeq Acc Id: NP_001162031   ⟸   NM_001168559
- UniProtKB: A6JU39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067057   ⟸   ENSRNOT00000072628
RefSeq Acc Id: ENSRNOP00000033579   ⟸   ENSRNOT00000037164
RefSeq Acc Id: XP_038960678   ⟸   XM_039104750
- Peptide Label: isoform X1
- UniProtKB: A6JU39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960679   ⟸   XM_039104751
- Peptide Label: isoform X2
- UniProtKB: A6JU39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960680   ⟸   XM_039104752
- Peptide Label: isoform X3
- UniProtKB: D4ACK1 (UniProtKB/TrEMBL),   A6JU39 (UniProtKB/TrEMBL)
Protein Domains
Anaphase-promoting complex subunit 4-like WD40   Nuclear pore complex protein Nup214 phenylalanine-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RBV9-F1-model_v2 AlphaFold M0RBV9 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304977 AgrOrtholog
BioCyc Gene G2FUF-50165 BioCyc
Ensembl Genes ENSRNOG00000023393 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000047244 Ensembl
Ensembl Transcript ENSRNOT00000037164.8 UniProtKB/TrEMBL
  ENSRNOT00000072628.3 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Apc4_WD40_dom UniProtKB/TrEMBL
  Nucleoporin UniProtKB/TrEMBL
  Nup214_FG UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
NCBI Gene 296634 ENTREZGENE
PANTHER NUCLEAR PORE COMPLEX PROTEIN NUP214 UniProtKB/TrEMBL
  PTHR23193 UniProtKB/TrEMBL
Pfam ANAPC4_WD40 UniProtKB/TrEMBL
  Nup214_FG UniProtKB/TrEMBL
PhenoGen Nup214 PhenoGen
RatGTEx ENSRNOG00000023393 RatGTEx
  ENSRNOG00000047244 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP Nucleoporin domain UniProtKB/TrEMBL
UniProt A6JU39 ENTREZGENE, UniProtKB/TrEMBL
  D4ACK1 ENTREZGENE, UniProtKB/TrEMBL
  M0RBV9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Nup214  nucleoporin 214  RGD1304977_predicted  similar to mKIAA0023 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1304977_predicted  similar to mKIAA0023 protein (predicted)  LOC296634_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296634_predicted  similar to mKIAA0023 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL