NUP214 (nucleoporin 214kDa) - Rat Genome Database

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Keyword

Gene: NUP214 (nucleoporin 214kDa) Homo sapiens

Symbol:

NUP214

Name:

nucleoporin 214kDa

Description:

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

214 kDa nucleoporin; CAIN; CAN; CAN protein, putative oncogene; D9S46E; MGC104525; N214; nuclear pore complex protein Nup214; nucleoporin 214kD (CAIN); nucleoporin Nup214; OTTHUMP00000022382; OTTHUMP00000022384; OTTHUMP00000229693; p250

Orthologs:

Mus musculus : Nup214 (nucleoporin 214) MGI
Rattus norvegicus : Nup214 (nucleoporin 214)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	9	134,014,029 - 134,122,200	+	NCBI
Human Genome Assembly HuRef	9	103,491,712 - 103,600,060	+	NCBI
Human Genome Assembly GRCh37	9	134,000,981 - 134,109,091	+	NCBI
Human Genome Assembly Build 36	9	132,990,802 - 133,098,912	+	NCBI
Human Cytogenetic Map	9	q34.1		NCBI
Human Genome Assembly	9	131,030,534 - 131,138,644		NCBI