| 2559 | Epo | erythropoietin | ENCODES a protein that exhibits cytokine activity (ortholog); erythropoietin receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN acute-phase response; negative regulation of cellular process; positive regulation of activated T cell proliferation; PARTICIPATES IN erythropoietin sign aling pathway; hypoxia inducible factor pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Acute-Phase Reaction; Brain Hypoxia-Ischemia; Brain Injuries; FOUND IN cell body; extracellular space; cell surface (ortholog); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 1H-indole | 12 | 24841285 | 24844725 | Rat | 453 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2560 | Epor | erythropoietin receptor | ENCODES a protein that exhibits erythropoietin receptor activity; identical protein binding (ortholog); INVOLVED IN cellular response to kainic acid; negative regulation of neuron apoptotic process; negative regulation of nitric oxide biosynthetic process; PARTICIPATES IN erythropoietin signaling pa thway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH Brain Hypoxia; Brain Injuries; brain ischemia; FOUND IN cell surface; external side of plasma membrane; plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 8 | 28765738 | 28770371 | Rat | 229 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1587434 | Epop | elongin BC and polycomb repressive complex 2 associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN neuron fate commitment (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell differentiation (ortholog); FOUND IN elongin complex (ortholog); ESC/E(Z) complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 83120767 | 83122287 | Rat | 86 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628627 | Cyp2b3 | cytochrome P450, family 2, subfamily b, polypeptide 3 | ENCODES a protein that exhibits anandamide 11,12 epoxidase activity (ortholog); anandamide 14,15 epoxidase activity (ortholog); anandamide 8,9 epoxidase activity (ortholog); INVOLVED IN response to Aroclor 1254; ketone metabolic process (ortholog); response to bacterium (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); acute myeloid leukemia (ortholog); autism spectrum disorder (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 1 | 90780468 | 90859852 | Rat | 1101 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593185 | Degs1l1 | delta(4)-desaturase, sphingolipid 1 like 1 | ENCODES a protein that exhibits sphingolipid delta-4 desaturase activity (inferred); INVOLVED IN lipid biosynthetic process (inferred); lipid metabolic process (inferred); sphingolipid biosynthetic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred) | 13 | 95304394 | 95351648 | Rat | 9 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 620088 | Cyp2b12 | cytochrome P450, family 2, subfamily b, polypeptide 12 | ENCODES a protein that exhibits arachidonate epoxygenase activity; INVOLVED IN epoxygenase P450 pathway; PARTICIPATES IN cytochrome P450 monooxygenase mediated pathway of arachidonic acid metabolism; arachidonic acid metabol ic pathway; phase I biotransformation pathway via cytochrome P450; FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH benzo[a]pyrene; copper atom; copper(0) | 1 | 91135294 | 91147094 | Rat | 43 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620370 | Cyp2c23 | cytochrome P450, family 2, subfamily c, polypeptide 23 | ENCODES a protein that exhibits arachidonate 11,12-epoxygenase activity; arachidonate 14,15-epoxygenase activity; arachidonate epoxygenase activity; INVOLVED IN epo 700;'>epoxygenase P450 pathway; icosanoid biosynthetic process; response to testosterone; PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; FOUND IN endoplasmic reticulum membrane; INTERACTS WITH (+)-schisandrin B; (R,R,R)-alpha-tocopherol; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | 1 | 252838427 | 252863081 | Rat | 103 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563697 | Cyp2c24 | cytochrome P450, family 2, subfamily c, polypeptide 24 | ENCODES a protein that exhibits arachidonate epoxygenase activity (ortholog); linoleic acid epoxygenase activity (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); linoleic acid metabolic process (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 1 | 246286341 | 246348607 | Rat | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308166 | Cyp2c79 | cytochrome P450, family 2, subfamily c, polypeptide 79 | ENCODES a protein that exhibits arachidonate epoxygenase activity (ortholog); caffeine oxidase activity (ortholog); estrogen 16-alpha-hydroxylase activity (ortholog); INVOLVED IN epoxygenase P450 pathway (ortholog); estrogen metabolic process (ortholog); icosanoid biosynthetic process (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); autism spectrum disorder (ortholog); chronic obstructive pulmonary disease (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | | | | Rat | 340 | description | gene, protein-coding |
| 631442 | Cyp2j3 | cytochrome P450, family 2, subfamily j, polypeptide 3 | ENCODES a protein that exhibits arachidonate 11,12-epoxygenase activity (inferred); arachidonate 14,15-epoxygenase activity (inferred); arachidonate epoxygenase activity (inferred); INVO LVED IN epoxygenase P450 pathway (inferred); icosanoid metabolic process (inferred); linoleic acid metabolic process (inferred); PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 116335755 | 116360677 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2557 | Ephx1 | epoxide hydrolase 1 | ENCODES a protein that exhibits cis-stilbene-oxide hydrolase activity; enzyme binding; epoxide hydrolase activity; INVOLVED IN cellular response to glucocorticoid stimulus; diol biosynthetic process; epoxide metabolic proces s; PARTICIPATES IN carbamazepine pharmacokinetics pathway; phenytoin pharmacodynamics pathway; bile acid transport pathway; ASSOCIATED WITH aflatoxins-related hepatocellular carcinoma; Experimental Liver Neoplasms; Abnormalities, Drug-Induced (ortholog); FOUND IN membrane; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 1-nitropropane | 13 | 95246079 | 95275852 | Rat | 649 | old_gene_name , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 620732 | Ephx2 | epoxide hydrolase 2 | ENCODES a protein that exhibits epoxide hydrolase activity; magnesium ion binding; phosphatase activity; INVOLVED IN epoxide metabolic process; linoleic acid metabolic process; positive regulation of blood pressure; PARTICIP ATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Acute Lung Injury; cerebral infarction; Hyperalgesia; FOUND IN peroxisome; cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 15 | 44465447 | 44503157 | Rat | 441 | old_gene_name , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307206 | Ephx3 | epoxide hydrolase 3 | ENCODES a protein that exhibits epoxide hydrolase activity (ortholog); INVOLVED IN epoxide metabolic process (ortholog); ASSOCIATED WITH melanoma (ortholog); Stomach Neoplasms (ortholog); FOUND IN membrane (ortholog); INTERA CTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; bisphenol A | 7 | 11857367 | 11862674 | Rat | 59 | name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303107 | Vkorc1 | vitamin K epoxide reductase complex, subunit 1 | ENCODES a protein that exhibits vitamin-K-epoxide reductase (warfarin-insensitive) activity; vitamin-K-epoxide reductase (warfarin-sensitive) activity; INVOLVED IN regulation of blood coagulation; blood coagulation (ortholog ); bone development (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Aortic Calcification; warfarin sensitivity; Aortic Rupture (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum lumen (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,4-dithiothreitol; 17alpha-ethynylestradiol | 1 | 191932969 | 191935490 | Rat | 242 | old_gene_name , name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 3755 | Sqle | squalene epoxidase | ENCODES a protein that exhibits squalene monooxygenase activity; FAD binding (ortholog); INVOLVED IN cholesterol metabolic process; response to biphenyl; cholesterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol e ster storage disease pathway; ASSOCIATED WITH cholelithiasis (ortholog); Experimental Liver Neoplasms (ortholog); Hypercholesterolemia (ortholog); FOUND IN cytoplasmic side of endoplasmic reticulum membrane (ortholog); endoplasmic reticulum membrane (ortholog); membrane (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 7 | 92758175 | 92773049 | Rat | 416 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308891 | Ephx4 | epoxide hydrolase 4 | ENCODES a protein that exhibits catalytic activity (inferred); epoxide hydrolase activity (inferred); hydrolase activity (inferred); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; cadmium dichloride | 14 | 2488282 | 2517558 | Rat | 40 | name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9191316 | LOC103693688 | epoxide hydrolase 1-like | | 13 | 95312882 | 95321716 | Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 1598239 | Btg1b | BTG anti-proliferation factor 1B | INTERACTS WITH epoxiconazole (ortholog) | X | 121665324 | 121671141 | Rat | 4 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 7555836 | Fam240a | family with sequence similarity 240 member A | INTERACTS WITH epoxiconazole (ortholog) | 8 | 119773705 | 119786169 | Rat | 1 | description | gene, protein-coding, MODEL [RefSeq] |
| 9071826 | Smim41 | small integral membrane protein 41 | INTERACTS WITH epoxiconazole (ortholog) | 7 | 134288923 | 134291997 | Rat | 1 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1303249 | Vkorc1l1 | vitamin K epoxide reductase complex subunit 1L1 | ENCODES a protein that exhibits vitamin-K-epoxide reductase (warfarin-sensitive) activity; INVOLVED IN vitamin K metabolic process; cellular response to oxidative stress (ortholog); peptidyl-glutamic acid carboxylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 32354078 | 32404327 | Rat | 124 | old_gene_name , name , description , ensembl_full_name | gene, protein-coding, VALIDATED [RefSeq] |
| 25394529 | Ephx2em2Mcwi | epoxide hydrolase 2;CRISPR/Cas9 induced mutant 2, Mcwi | CRISPR/Cas9 system was used to introduce a mutation in the Crl:SD rat embryos. The resulting mutation is a a 23-bp deletion in exon 3. | | | | Rat | | name | gene, allele |
| 402385208 | LOC134480120 | vitamin K epoxide reductase complex subunit 1-like protein 1 | | 8 | 22576013 | 22576681 | Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 2321540 | Vkorc1l1-ps1 | vitamin K epoxide reductase complex, subunit 1-like 1, pseudogene 1 | | X | 86350524 | 86350909 | Rat | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 70493 | Alox15 | arachidonate 15-lipoxygenase | ENCODES a protein that exhibits arachidonate 12(S)-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; INVOLVED IN arachidonate metabolic process; hepo ;'>epoxilin biosynthetic process; linoleic acid metabolic process; PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; ASSOCIATED WITH brain ischemia; congestive heart failure; glomerulonephritis; FOUND IN cytosol; cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 55559060 | 55567535 | Rat | 370 | old_gene_name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 41140059 | Snora78 | small nucleolar RNA, H/ACA box 78 | INTERACTS WITH benzo[a]pyrene diol epoxide I (ortholog); sodium arsenite (ortholog) | 10 | 14251417 | 14251544 | Rat | 2 | description | gene, snorna, MODEL [RefSeq] |
| 620955 | Lss | lanosterol synthase | ENCODES a protein that exhibits lanosterol synthase activity; INVOLVED IN cholesterol biosynthetic process; sterol metabolic process; cholesterol biosynthetic process via desmosterol (ortholog); PARTICIPATES IN cholesterol biosynthetic pathway; alendronate pharmacodynamics pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH alopecia-mental retardation syndrome 4 (ortholog); cataract (ortholog); cataract 44 (ortholog); FOUND IN cytoplasmic side of endoplasmic reticulum membrane (ortholog); endoplasmic reticulum membrane (ortholog); lipid droplet (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 20 | 12090641 | 12118230 | Rat | 392 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 7587328 | Smim35 | small integral membrane protein 35 | INTERACTS WITH bisphenol A (ortholog); epoxiconazole (ortholog); fulvestrant (ortholog) | 8 | 54395878 | 54457757 | Rat | 3 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620957 | Ebp | EBP, cholestenol delta-isomerase | ENCODES a protein that exhibits C-8 sterol isomerase activity; cholestenol delta-isomerase activity (ortholog); cholesterol-5,6-oxide hydrolase activity (ortholog); INVOLVED IN cholesterol biosynthetic process; cholesterol biosynthetic process via desmosterol (ortholog); cholesterol biosynthetic pro cess via lathosterol (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH autosomal recessive congenital ichthyosis (ortholog); chondrodysplasia punctata (ortholog); connective tissue disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); nuclear envelope (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine | X | 16971372 | 16977782 | Rat | 272 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621769 | Dhcr7 | 7-dehydrocholesterol reductase | ENCODES a protein that exhibits 7-dehydrocholesterol reductase activity; cholesterol-5,6-oxide hydrolase activity (ortholog); NADP binding (ortholog); INVOLVED IN cholesterol biosynthetic process; regulation of cholesterol biosynthetic process; blood vessel development (ortholog); PARTICIPATES IN ch olesterol biosynthetic pathway; steroid biosynthetic pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Animal Disease Models (ortholog); autistic disorder (ortholog); FOUND IN endoplasmic reticulum (ortholog); nuclear outer membrane (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 1 | 208444434 | 208460408 | Rat | 374 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 15004259 | AABR07039936.1 | | ENCODES a protein that exhibits vitamin-K-epoxide reductase (warfarin-sensitive) activity (inferred); INVOLVED IN vitamin K metabolic process (inferred) | | | | Rat | 4 | description | gene, protein-coding |
| 1559644 | Aadacl4fm3 | AADACL4 family member 3 | ENCODES a protein that exhibits hydrolase activity (inferred); INTERACTS WITH Cuprizon; 4,4'-sulfonyldiphenol (ortholog); epoxiconazole (ortholog) | 5 | 161846218 | 161884648 | Rat | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 620311 | Akr7a2 | aldo-keto reductase family 7, member A2 | ENCODES a protein that exhibits alcohol dehydrogenase (NADP+) activity; phenanthrene-9,10-epoxide hydrolase activity (ortholog); INVOLVED IN daunorubicin metabolic process (ortholog); doxorubicin metabolic process (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); autism spectrum disorder (ortholog); pancreatic ductal adenocarcinoma (ortholog); FOUND IN cytosol; Golgi apparatus; nuclear envelope; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol | 5 | 156835589 | 156844127 | Rat | 219 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1595434 | Cldn34b3 | claudin 34B3 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred); INTERACTS WITH epoxiconazole (ortholog) | X | 44126472 | 44131251 | Rat | 6 | description | gene, protein-coding, MODEL [RefSeq] |
| 2318711 | Cldn34b4 | claudin 34B4 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred); INTERACTS WITH epoxiconazole (ortholog); sodium arsenite (ortholog) | X | 44329083 | 44362148 | Rat | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 1597405 | Cstdc2 | cystatin domain containing 2 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH crocidolite asbestos (ortholog); epoxiconazole (ortholog); ozone (ortholo g) | 3 | 156756863 | 156789790 | Rat | 9 | description | gene, protein-coding, PREDICTED [RefSeq] |
| 2469 | Cyp2c11 | cytochrome P450, subfamily 2, polypeptide 11 | ENCODES a protein that exhibits arachidonate 11,12-epoxygenase activity; arachidonate 14,15-epoxygenase activity; monooxygenase activity; INVOLVED IN epoxygenase P450 pathway; icosanoid biosynthetic process; retinoic acid metabolic process (ortholog); PARTICIPATES IN forkhead class A signaling pathway; warfarin pharmacokinetics pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH abnormal xenobiotic pharmacokinetics; decreased litter size; delayed fertility; ASSOCIATED WITH Cardiomegaly; Chemical and Drug Induced Liver Injury; depressive disorder; FOUND IN endoplasmic reticulum membrane; INTERACTS WITH 1,2-dichloroethene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 1 | 246175216 | 246211445 | Rat | 356 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619934 | Cyp2c6 | cytochrome P450, family 2, subfamily C, polypeptide 6 | ENCODES a protein that exhibits monooxygenase activity; arachidonate 14,15-epoxygenase activity (ortholog); enzyme binding (ortholog); INVOLVED IN response to nutrient levels; response to oxygen-containing compound; response to xenobiotic stimulus; PARTICIPATES IN axitinib pharmacokinetics pathway; carbamazepine pharmacokinetics pathway; citalopram pharmacodynamics pathway; ASSOCIATED WITH type 2 diabetes mellitus; Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1,2-dichloroethene; 17alpha-ethynylestradiol | 1 | 247879058 | 247916804 | Rat | 847 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620007 | Cyp2j4 | cytochrome P450, family 2, subfamily j, polypeptide 4 | ENCODES a protein that exhibits arachidonate monooxygenase activity; NADPH-hemoprotein reductase activity; arachidonate 11,12-epoxygenase activity (ortholog); INVOLVED IN arachidonate metabolic process; female pregnancy; negative regulation of collagen biosynthe tic process; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH abnormal extracellular matrix morphology; abnormal tumor necrosis factor level; increased body weight; ASSOCIATED WITH bacterial pneumonia; nephritis; pre-eclampsia; FOUND IN endoplasmic reticulum membrane; endoplasmic reticulum (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 1H-pyrazole | 5 | 116295691 | 116323219 | Rat | 305 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628719 | Cyp4x1 | cytochrome P450, family 4, subfamily x, polypeptide 1 | ENCODES a protein that exhibits anandamide 14,15 epoxidase activity (ortholog); INVOLVED IN lipid metabolic process (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 6-propyl-2-thi ouracil; ammonium chloride; bisphenol A | 5 | 133888439 | 133923254 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2320917 | Dytn | dystrotelin | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN synapse (inferred); INTERACTS WITH benzo[a]pyrene (ortholog); chlorpyrifos (ortholog); epoxiconazole (ortholog) | 9 | 72531151 | 72592486 | Rat | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 1564437 | Foxr2 | forkhead box R2 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Nerve Sheath Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxin e (ortholog); epoxiconazole (ortholog) | X | 21618111 | 21651791 | Rat | 13 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1590640 | Ftdc2 | ferritin domain containing 2 | ENCODES a protein that exhibits ferric iron binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl (ortholog); epo ght:700;'>epoxiconazole (ortholog) | 11 | 55437980 | 55441566 | Rat | 8 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311333 | Lta4h | leukotriene A4 hydrolase | ENCODES a protein that exhibits leukotriene-A4 hydrolase activity; aminopeptidase activity (ortholog); epoxide hydrolase activity (ortholog); INVOLVED IN leukotriene metabolic process; response to peptide hormone; response to zinc ion; PARTICIPATES IN acetylsali cylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH adenocarcinoma; asthma; squamous cell carcinoma; FOUND IN cytosol (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 7 | 29856846 | 29888642 | Rat | 220 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2323009 | Mdfic2 | MyoD family inhibitor domain containing 2 | INVOLVED IN regulation of gene expression (inferred); INTERACTS WITH 17beta-estradiol (ortholog); bisphenol A (ortholog); epoxiconazole (ortholog) | 4 | 132401899 | 132504412 | Rat | 8 | description | gene, protein-coding, MODEL [RefSeq] |
| 7639871 | Ms4a20 | membrane-spanning 4-domains, subfamily A, member 20 | INTERACTS WITH Butylbenzyl phthalate (ortholog); epoxiconazole (ortholog); titanium dioxide (ortholog) | 1 | 217176490 | 217223881 | Rat | 3 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1333039 | Or10g9 | olfactory receptor family 10 subfamily G member 9 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH benzo[a]pyrene (ortholog); epoxiconazole (ortholog); titanium dioxide (ortholog) | 8 | 49249594 | 49250529 | Rat | 22 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 7545650 | Potefam2 | POTE ankyrin domain family member 2 | INTERACTS WITH atrazine (ortholog); bis(2-ethylhexyl) phthalate (ortholog); epoxiconazole (ortholog) | 1 | 125680543 | 125859269 | Rat | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 11384727 | Smim43 | small integral membrane protein 43 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN mesendoderm development (ortholog); positive regulation of D-glucose transmembrane transport (ortholog); ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); benzo[a]pyrene (ortholog); benzo[a]pyrene diol epoxide I (ortholog) | 2 | 121304262 | 121314779 | Rat | 24 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 6486156 | Zfp936 | zinc finger protein 936 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); epoxiconazole (ortholog); sodium arsenite (ortholog) | 1 | 102080136 | 102084246 | Rat | 5 | description | gene, pseudo, MODEL [RefSeq] |