RPS6 (ribosomal protein S6) - Rat Genome Database

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Gene: RPS6 (ribosomal protein S6) Sus scrofa
Analyze
Symbol: RPS6
Name: ribosomal protein S6
RGD ID: 14085846
Description: ENCODES a protein that exhibits mRNA binding (ortholog); structural constituent of ribosome (ortholog); INVOLVED IN activation-induced cell death of T cells (ortholog); cellular response to ethanol (ortholog); erythrocyte development (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Experimental Autoimmune Myocarditis (ortholog); FOUND IN cytoplasm; nucleus; perinuclear region of cytoplasm; INTERACTS WITH anthra[1,9-cd]pyrazol-6(2H)-one; bifenthrin; etoxazole
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,444,450 - 203,451,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,444,360 - 203,447,643 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,094,866 - 227,098,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:23486913   PMID:30032202  


Genomics

Comparative Map Data
RPS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,444,450 - 203,451,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,444,360 - 203,447,643 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,094,866 - 227,098,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,375,715 - 19,380,236 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl919,375,715 - 19,380,236 (-)EnsemblGRCh38hg38GRCh38
GRCh37919,375,713 - 19,380,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,366,254 - 19,370,235 (-)NCBINCBI36Build 36hg18NCBI36
Build 34919,366,253 - 19,370,235NCBI
Celera919,302,350 - 19,306,331 (-)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,337,814 - 19,341,795 (-)NCBIHuRef
CHM1_1919,376,051 - 19,380,032 (-)NCBICHM1_1
T2T-CHM13v2.0919,388,517 - 19,393,023 (-)NCBIT2T-CHM13v2.0
Rps6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,772,336 - 86,775,604 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,772,897 - 86,775,649 (-)EnsemblGRCm39 Ensembl
GRCm38486,854,099 - 86,857,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,854,660 - 86,857,412 (-)EnsemblGRCm38mm10GRCm38
MGSCv37486,500,003 - 86,503,271 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,325,893 - 86,328,588 (-)NCBIMGSCv36mm8
Celera485,374,929 - 85,378,195 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
Rps6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85106,417,680 - 106,420,540 (-)NCBIGRCr8
mRatBN7.25101,371,716 - 101,374,576 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl566,681,075 - 66,681,919 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl5101,371,136 - 101,374,602 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,752,605 - 103,755,465 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05105,543,160 - 105,546,020 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05105,576,526 - 105,579,388 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05105,197,821 - 105,200,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,197,857 - 105,200,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,209,846 - 105,212,173 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,184,689 - 109,187,549 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,165,612 - 106,168,472 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5101,709,190 - 101,712,050 (+)NCBICelera
Cytogenetic Map5q32NCBI
Rps6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,744,082 - 21,746,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,744,045 - 21,745,646 (-)NCBIChiLan1.0ChiLan1.0
RPS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211105,135,133 - 105,170,654 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19105,141,077 - 105,176,598 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0919,185,455 - 19,189,504 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1919,674,380 - 19,678,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,674,380 - 19,677,722 (-)Ensemblpanpan1.1panPan2
RPS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11139,161,422 - 39,165,148 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1139,161,422 - 39,165,148 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1137,819,139 - 37,822,865 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01140,094,843 - 40,098,569 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1140,094,843 - 40,098,569 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,787,210 - 38,790,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,584,732 - 38,588,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01139,218,708 - 39,222,435 (-)NCBIUU_Cfam_GSD_1.0
Rps6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,583,479 - 153,586,550 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366521,253,025 - 1,255,906 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366521,252,986 - 1,255,987 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,353,800 - 60,357,797 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,353,817 - 60,357,759 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603848,467,090 - 48,471,105 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,328,002 - 23,336,140 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473623,332,556 - 23,336,234 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RPS6
102 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005698   ⟹   ENSSSCP00000005557
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,444,450 - 203,451,468 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000036713   ⟹   ENSSSCP00000054169
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,444,450 - 203,451,468 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000055612   ⟹   ENSSSCP00000054808
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,444,984 - 203,451,468 (+)Ensembl
RefSeq Acc Id: XM_003121890   ⟹   XP_003121938
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,444,360 - 203,447,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005660083   ⟹   XP_005660140
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,444,451 - 203,447,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063193   ⟹   XP_020918852
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,444,453 - 203,447,643 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003121938   ⟸   XM_003121890
- Peptide Label: isoform X1
- UniProtKB: A0A8D1U697 (UniProtKB/TrEMBL),   F2Z5Q6 (UniProtKB/TrEMBL),   A0A8D0IYN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005660140   ⟸   XM_005660083
- Peptide Label: isoform X2
- UniProtKB: A0A4X1WBG6 (UniProtKB/TrEMBL),   A0A8D0IQY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918852   ⟸   XM_021063193
- Peptide Label: isoform X2
- UniProtKB: A0A4X1WBG6 (UniProtKB/TrEMBL),   A0A8D0IQY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000005557   ⟸   ENSSSCT00000005698
RefSeq Acc Id: ENSSSCP00000054169   ⟸   ENSSSCT00000036713
RefSeq Acc Id: ENSSSCP00000054808   ⟸   ENSSSCT00000055612


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005016347 UniProtKB/TrEMBL
  ENSSSCG00015005739 UniProtKB/TrEMBL
  ENSSSCG00030063978 UniProtKB/TrEMBL
  ENSSSCG00040010636 UniProtKB/TrEMBL
  ENSSSCG00045012859 UniProtKB/TrEMBL
  ENSSSCG00050043372 UniProtKB/TrEMBL
  ENSSSCG00055019311 UniProtKB/TrEMBL
  ENSSSCG00070030240 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005698 ENTREZGENE
  ENSSSCT00000005698.4 UniProtKB/TrEMBL
  ENSSSCT00000036713.3 UniProtKB/TrEMBL
  ENSSSCT00000055612 ENTREZGENE
  ENSSSCT00000055612.3 UniProtKB/TrEMBL
  ENSSSCT00005025856.1 UniProtKB/TrEMBL
  ENSSSCT00005025895.1 UniProtKB/TrEMBL
  ENSSSCT00005025917.1 UniProtKB/TrEMBL
  ENSSSCT00015007674.1 UniProtKB/TrEMBL
  ENSSSCT00015007682.1 UniProtKB/TrEMBL
  ENSSSCT00015007695.1 UniProtKB/TrEMBL
  ENSSSCT00030089540.1 UniProtKB/TrEMBL
  ENSSSCT00030089574.1 UniProtKB/TrEMBL
  ENSSSCT00040013933.1 UniProtKB/TrEMBL
  ENSSSCT00040013977.1 UniProtKB/TrEMBL
  ENSSSCT00045022016.1 UniProtKB/TrEMBL
  ENSSSCT00045022032.1 UniProtKB/TrEMBL
  ENSSSCT00045022070.1 UniProtKB/TrEMBL
  ENSSSCT00050059067.1 UniProtKB/TrEMBL
  ENSSSCT00050059070.1 UniProtKB/TrEMBL
  ENSSSCT00055037989.1 UniProtKB/TrEMBL
  ENSSSCT00055038063.1 UniProtKB/TrEMBL
  ENSSSCT00070060850.1 UniProtKB/TrEMBL
  ENSSSCT00070060851.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.2650 UniProtKB/TrEMBL
InterPro Ribosomal_S6_euk UniProtKB/TrEMBL
  Ribosomal_S6e UniProtKB/TrEMBL
  Ribosomal_S6e_CS UniProtKB/TrEMBL
KEGG Report ssc:100038023 UniProtKB/TrEMBL
NCBI Gene RPS6 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S6 UniProtKB/TrEMBL
  PTHR11502 UniProtKB/TrEMBL
Pfam Ribosomal_S6e UniProtKB/TrEMBL
PIRSF Ribosom_S6_euk UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S6E UniProtKB/TrEMBL
SMART Ribosomal_S6e UniProtKB/TrEMBL
UniProt A0A287BCW5_PIG UniProtKB/TrEMBL
  A0A287BE54_PIG UniProtKB/TrEMBL
  A0A4X1W613_PIG UniProtKB/TrEMBL
  A0A4X1WBG6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IQY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IW47_PIG UniProtKB/TrEMBL
  A0A8D0IYN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1U697 ENTREZGENE, UniProtKB/TrEMBL
  A1XQU8_PIG UniProtKB/TrEMBL
  F2Z5Q6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:103166 ENTREZGENE