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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:testosterone biosynthetic pathway
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Accession:PW:0000778 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of testosterone, a C19-steroid hormone secreted primarily in the testes and ovaries and to a lesser extend by the adrenal glands.
Synonyms:related_synonym: testosterone biosynthetic process
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testosterone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 ISO RGD PMID:18821018 RGD:2325883 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sts steroid sulfatase ISO RGD PMID:21693170 RGD:6893583 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        isoprenoid metabolic pathway 95
          isoprenoid biosynthetic pathway 82
            steroid biosynthetic pathway 82
              steroid hormone biosynthetic pathway 55
                C19-steroid hormone biosynthetic pathway 14
                  testosterone biosynthetic pathway 14
paths to the root