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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:isoprenoid metabolic pathway
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Accession:PW:0000248 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of isoprenoids or terpenoids - a large class of organic biomolecules. Isoprenoids are precursors of sterols such as cholesterol and its derivatives and also of non-sterol molecules, many of which are used in the post-translational modification of proteins. Plant isoprenoids are among the most commonly found and have a broad range of uses and applications in plants and beyond.
Synonyms:related_synonym: isoprenoid metabolic process;   terpenoid metabolic pathway


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isoprenoid metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 IDA RGD PMID:4392955 RGD:2303525 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IDA RGD PMID:4392955 PMID:12441193 RGD:2303525, RGD:2303535 NCBI chr 2:186,008,944...186,028,417
Ensembl chr 2:186,008,943...186,020,393 		JBrowse link
aldosterone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 TAS RGD PMID:15583024 RGD:4889549 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:17926129 RGD:4892309 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
bile acid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox2 acyl-CoA oxidase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 ISO SMPDB SMP:00035 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Ch25h cholesterol 25-hydroxylase IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442 		JBrowse link
G Lipa lipase A, lysosomal acid type ISO SMPDB SMP:00035 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Scp2 sterol carrier protein 2 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 IEA
ISO		 KEGG
SMPDB		 SMP:00035 rno:00120 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
C21-steroid hormone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IDA RGD PMID:11832364 RGD:727991 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 IDA RGD PMID:7829497 RGD:1299585 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
cholesterol biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Cyp51 cytochrome P450, family 51 ISO
IDA		 SMPDB
RGD		 PMID:16876788 PMID:7581240 PMID:12668600 SMP:00023, RGD:2316857, RGD:2316902, RGD:2316868 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase ISO SMPDB
RGD		 PMID:16876788 PMID:12668600 SMP:00023, RGD:2316857, RGD:2316868 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase ISO
IMP		 RGD PMID:16876788 PMID:9831636 PMID:12668600 RGD:2316857, RGD:2316918, RGD:2316868 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase ISO SMPDB
RGD		 PMID:16876788 PMID:12668600 SMP:00023, RGD:2316857, RGD:2316868 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 IMP
ISO		 SMPDB
RGD		 PMID:16440058 PMID:16876788 SMP:00023, RGD:1626611, RGD:2316857 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 ISO SMPDB SMP:00023 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 ISO SMPDB SMP:00023 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Lbr lamin B receptor ISO RGD PMID:16876788 PMID:12668600 RGD:2316857, RGD:2316868 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Lipa lipase A, lysosomal acid type ISO SMPDB SMP:00023 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lss lanosterol synthase IMP
ISO
IDA		 SMPDB
RGD		 PMID:16440058 PMID:1429550 PMID:16876788 SMP:00023, RGD:1626611, RGD:2316919, RGD:2316857 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 ISO SMPDB SMP:00023 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Mvk mevalonate kinase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like ISO SMPDB
RGD		 PMID:16876788 PMID:12668600 SMP:00023, RGD:2316857, RGD:2316868 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Pmvk phosphomevalonate kinase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364 		JBrowse link
G Sc5d sterol-C5-desaturase ISO
IDA		 SMPDB
RGD		 PMID:16876788 PMID:7961720 PMID:12668600 SMP:00023, RGD:2316857, RGD:2316911, RGD:2316868 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Soat1 sterol O-acyltransferase 1 ISO SMPDB SMP:00023 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Sqle squalene epoxidase ISO SMPDB
RGD		 PMID:16876788 SMP:00023, RGD:2316857 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 ISO SMPDB SMP:00023 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
cortisol biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:17926129 RGD:4892309 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
estradiol biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 TAS
ISO		 RGD PMID:15583024 PMID:18821018 RGD:4889549, RGD:2325883 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 ISO RGD PMID:18821018 RGD:2325883 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:17926129 RGD:4892309 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sts steroid sulfatase ISO RGD PMID:21693170 RGD:6893583 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 ISO RGD PMID:21693170 RGD:6893583 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
primary bile acid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox2 acyl-CoA oxidase 2 IEA KEGG rno:00120 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 IEA KEGG rno:00120 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase IEA KEGG rno:00120 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase IEA KEGG rno:00120 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Ch25h cholesterol 25-hydroxylase IEA KEGG rno:00120 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 IEA KEGG rno:00120 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 IEA KEGG rno:00120 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 IEA KEGG rno:00120 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IEA KEGG rno:00120 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 IEA KEGG rno:00120 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 IEA KEGG rno:00120 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 IEA KEGG rno:00120 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IEA KEGG rno:00120 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442 		JBrowse link
G Scp2 sterol carrier protein 2 IEA KEGG rno:00120 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 IEA KEGG rno:00120 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
steroid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cel carboxyl ester lipase IEA KEGG rno:00100 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IEA KEGG rno:00100 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 IEA KEGG rno:00100 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp51 cytochrome P450, family 51 IEA KEGG rno:00100 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase IEA KEGG rno:00100 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IEA KEGG rno:00100 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase IEA KEGG rno:00100 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 IEA KEGG rno:00100 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 IEA KEGG rno:00100 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Lipa lipase A, lysosomal acid type IEA KEGG rno:00100 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lss lanosterol synthase IEA KEGG rno:00100 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like IEA KEGG rno:00100 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Sc5d sterol-C5-desaturase IEA KEGG rno:00100 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Soat1 sterol O-acyltransferase 1 IEA KEGG rno:00100 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Soat2 sterol O-acyltransferase 2 IEA KEGG rno:00100 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915 		JBrowse link
G Sqle squalene epoxidase IEA KEGG rno:00100 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 IEA KEGG rno:00100 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
steroid hormone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 ISO SMPDB SMP:00130 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 IEA
ISO		 KEGG
SMPDB		 SMP:00130 rno:00140 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Comt catechol-O-methyltransferase IEA KEGG rno:00140 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO
IEA		 SMPDB
KEGG
RGD		 PMID:18821018 SMP:00130 rno:00140, RGD:2325883 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IEA KEGG rno:00140 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IEA
ISO		 KEGG
SMPDB		 SMP:00130 rno:00140 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 IEA
ISO		 KEGG
SMPDB		 SMP:00130 rno:00140 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO
IEA		 SMPDB
KEGG
RGD		 PMID:18821018 SMP:00130 rno:00140, RGD:2325883 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO
IEA		 KEGG
RGD		 PMID:15583024 rno:00140, RGD:4889549 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEA KEGG rno:00140 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEA KEGG rno:00140 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 IEA KEGG rno:00140 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923 		JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 IEA KEGG rno:00140 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IEA KEGG rno:00140 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IEA KEGG rno:00140 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 IEA KEGG rno:00140 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IEA KEGG rno:00140 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 IEA KEGG rno:00140 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00130 rno:00140 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00130 rno:00140 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 IEA KEGG rno:00140 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 IEA KEGG rno:00140 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 IEA KEGG rno:00140 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEA KEGG rno:00140 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 IEA KEGG rno:00140 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 IEA KEGG rno:00140 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 IEA KEGG rno:00140 NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO SMPDB
RGD		 PMID:15583024 SMP:00130, RGD:4889549 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEA
ISO		 KEGG
SMPDB
RGD		 PMID:15583024 SMP:00130 rno:00140, RGD:4889549 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IEA KEGG rno:00140 NCBI chr 2:186,008,944...186,028,417
Ensembl chr 2:186,008,943...186,020,393 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEA KEGG rno:00140 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEA KEGG rno:00140 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 IEA KEGG rno:00140 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sts steroid sulfatase IEA KEGG rno:00140 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 IEA KEGG rno:00140 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 IEA KEGG rno:00140 NCBI chr 1:75,909,585...75,976,600
Ensembl chr 1:75,839,716...75,976,579 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 IEA KEGG rno:00140 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IEA KEGG rno:00140 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 IEA KEGG rno:00140 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 IEA KEGG rno:00140 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 IEA KEGG rno:00140 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IEA KEGG rno:00140 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IEA KEGG rno:00140 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 IEA KEGG rno:00140 NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 IEA KEGG rno:00140 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 IEA KEGG rno:00140 NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 IEA KEGG rno:00140 NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B IEA KEGG rno:00140 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IEA KEGG rno:00140 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 IEA KEGG rno:00140 NCBI chr14:20,817,285...20,833,917
Ensembl chr14:20,817,285...20,833,917 		JBrowse link
testosterone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 ISO RGD PMID:18821018 RGD:2325883 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:18821018 RGD:2325883 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sts steroid sulfatase ISO RGD PMID:21693170 RGD:6893583 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        isoprenoid metabolic pathway 95
          abscisic acid metabolic pathway + 0
          altered isoprenoid metabolic pathway + 0
          isoprenoid biosynthetic pathway + 82
          steroid metabolic pathway + 94
paths to the root