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ONTOLOGY REPORT - ANNOTATIONS

Term:protein K63-linked ubiquitination
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Accession:GO:0070534 term browser browse the term
Definition:A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
Synonyms:exact_synonym: protein K63-linked polyubiquitination


show annotations for term's descendants           Sort by:
protein K63-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IDA (PMID:19340006) UniProt PMID:19340006 NCBI chr 3:48,918,842...48,986,382
Ensembl chr 3:48,918,821...48,986,382 		JBrowse link
G ARRDC4 arrestin domain containing 4 involved_in IDA (PMID:28594402) UniProt PMID:28594402 NCBI chr15:97,960,703...97,973,833
Ensembl chr15:97,960,703...97,973,833 		JBrowse link
G BFAR bifunctional apoptosis regulator involved_in IDA (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:14,632,951...14,669,236
Ensembl chr16:14,632,931...14,669,236 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in IDA (PMID:18305112) UniProt PMID:18305112 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G HECTD1 HECT domain E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:22431752) GO_Central
MGI
TreeGrafter		 PMID:22431752 GO_REF:0000033 GO_REF:0000118 NCBI chr14:31,100,117...31,207,793
Ensembl chr14:31,100,117...31,207,804 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in IBA
IDA
IEA		 (PMID:18718448), (PMID:19592251), (PMID:29378950) GO_Central
UniProt
TreeGrafter		 PMID:18718448 PMID:19592251 PMID:29378950 GO_REF:0000033 GO_REF:0000118 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G KCMF1 potassium channel modulatory factor 1 involved_in IDA (PMID:34893540) UniProt PMID:34893540 NCBI chr 2:84,971,161...85,059,472
Ensembl chr 2:84,971,093...85,059,472 		JBrowse link
G LOC122513141 ring finger protein-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:137,217,494...137,219,361
Ensembl chr 9:137,217,452...137,219,361 		JBrowse link
G MAGEL2 MAGE family member L2 involved_in IMP (PMID:23452853) UniProt PMID:23452853 NCBI chr15:23,643,549...23,647,867
Ensembl chr15:23,643,549...23,647,867 		JBrowse link
G NBN nibrin involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase involved_in ISS UniProt GO_REF:0000024 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G PEDS1-UBE2V1 PEDS1-UBE2V1 readthrough involved_in IDA
IBA		 (PMID:16307917), (PMID:21512573), (PMID:31006531) UniProt
GO_Central		 PMID:16307917 PMID:21512573 PMID:31006531 GO_REF:0000033 NCBI chr20:50,081,124...50,153,723
Ensembl chr20:50,081,124...50,153,637 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in IMP
IDA		 (PMID:29883609)
(PMID:30952868), (PMID:33215753)		 UniProt PMID:29883609 PMID:30952868 PMID:33215753 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:23892723) GO_Central
MGI
TreeGrafter		 PMID:23892723 GO_REF:0000033 GO_REF:0000118 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (MGI:5780352|PMID:26774286) UniProt PMID:26774286 MGI:5780352 NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA
NAS
TAS		 (PMID:15728840), (PMID:17314283), (PMID:19880420), (PMID:25621951)
(PMID:20890124)
(PMID:18221368)		 UniProt
ParkinsonsUK-UCL		 PMID:15728840 PMID:17314283 PMID:18221368 PMID:19880420 PMID:20890124 More... NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PRPF19 pre-mRNA processing factor 19 involved_in IMP
IEA		 (PMID:20595234), (PMID:24332808) UniProt PMID:20595234 PMID:24332808 GO_REF:0000104 NCBI chr11:60,890,547...60,906,585
Ensembl chr11:60,890,547...60,906,585 		JBrowse link
G RNF115 ring finger protein 115 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095 		JBrowse link
G RNF126 ring finger protein 126 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:647,526...663,214
Ensembl chr19:647,526...663,233 		JBrowse link
G RNF135 ring finger protein 135 involved_in IDA (PMID:31006531) UniProt PMID:31006531 NCBI chr17:30,958,921...30,999,911
Ensembl chr17:30,970,984...30,999,911 		JBrowse link
G RNF152 ring finger protein 152 involved_in IMP (PMID:25936802) UniProt PMID:25936802 NCBI chr18:61,808,067...61,894,412
Ensembl chr18:61,808,067...61,894,247 		JBrowse link
G RNF167 ring finger protein 167 involved_in IDA (PMID:35114100) UniProt PMID:35114100 NCBI chr17:4,940,092...4,945,222
Ensembl chr17:4,940,008...4,945,222 		JBrowse link
G RNF168 ring finger protein 168 involved_in IDA (PMID:22266820) UniProt PMID:22266820 NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768 		JBrowse link
G RNF186 ring finger protein 186 involved_in IDA
IBA		 (PMID:23896122) UniProt
GO_Central		 PMID:23896122 GO_REF:0000033 NCBI chr 1:19,814,029...19,815,283
Ensembl chr 1:19,814,029...19,815,283 		JBrowse link
G RNF213 ring finger protein 213 involved_in IDA (PMID:32139119), (PMID:33842849) UniProt PMID:32139119 PMID:33842849 NCBI chr17:80,260,852...80,398,794
Ensembl chr17:80,260,852...80,398,794 		JBrowse link
G RNF4 ring finger protein 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:2,469,106...2,515,857
Ensembl chr 4:2,462,220...2,515,857 		JBrowse link
G RNF5 ring finger protein 5 involved_in IDA (PMID:19269966) UniProt PMID:19269966 NCBI chr 6:32,178,405...32,180,793
Ensembl chr 6:32,178,405...32,180,793 		JBrowse link
G RNF8 ring finger protein 8 involved_in IDA (PMID:21911360) UniProt PMID:21911360 NCBI chr 6:37,353,983...37,394,734
Ensembl chr 6:37,353,979...37,394,734 		JBrowse link
G SKP2 S-phase kinase associated protein 2 involved_in IDA
IEA		 (PMID:22464731) UniProt
Ensembl		 PMID:22464731 GO_REF:0000107 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IDA (PMID:16307917) UniProt PMID:16307917 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G TRAF1 TNF receptor associated factor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IDA
IEA
IBA		 (PMID:15258597), (PMID:20577214) UniProt
TreeGrafter
GO_Central		 PMID:15258597 PMID:20577214 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IDA (PMID:19825828) UniProt PMID:19825828 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TRAF4 TNF receptor associated factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:28,744,011...28,750,956
Ensembl chr17:28,744,011...28,750,956 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,615...211,374,946 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IGI
IBA
IDA
IEA		 (PMID:17135271), (PMID:19675569)
(PMID:19713527), (PMID:20038579), (PMID:21068390), (PMID:23015697), (PMID:23524951), (PMID:33799071)		 UniProt
GO_Central
ParkinsonsUK-UCL
Ensembl		 PMID:17135271 PMID:19675569 PMID:19713527 PMID:20038579 PMID:21068390 More... GO_REF:0000033 GO_REF:0000107 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIM21 tripartite motif containing 21 involved_in IMP
IDA		 (PMID:26342464)
(PMID:36692217), (PMID:37816088)		 UniProt PMID:26342464 PMID:36692217 PMID:37816088 NCBI chr11:4,384,897...4,393,702
Ensembl chr11:4,384,897...4,393,702 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in IDA (PMID:36159777) UniProt PMID:36159777 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TRIM27 tripartite motif containing 27 involved_in IMP
IEA
IBA		 (PMID:23452853) UniProt
TreeGrafter
GO_Central		 PMID:23452853 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988 		JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IDA (PMID:32878999) UniProt PMID:32878999 NCBI chr11:6,448,613...6,474,459
Ensembl chr11:6,448,613...6,474,459 		JBrowse link
G TRIM31 tripartite motif containing 31 involved_in IDA (PMID:27992402) UniProt PMID:27992402 NCBI chr 6:30,102,897...30,113,090
Ensembl chr 6:30,102,897...30,113,090 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:37943659) UniProt PMID:37943659 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
G TRIM5 tripartite motif containing 5 involved_in IDA (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967 		JBrowse link
G TRIM65 tripartite motif containing 65 involved_in IDA
IEA		 (PMID:28594402) UniProt
Ensembl		 PMID:28594402 GO_REF:0000107 NCBI chr17:75,879,537...75,896,951
Ensembl chr17:75,880,335...75,896,951 		JBrowse link
G TRIM8 tripartite motif containing 8 involved_in IDA (PMID:27995356) UniProt PMID:27995356 NCBI chr10:102,644,479...102,658,319
Ensembl chr10:102,642,503...102,658,318 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B involved_in IDA (PMID:20061386) UniProt PMID:20061386 NCBI chr 5:134,371,569...134,392,108
Ensembl chr 5:134,371,184...134,392,108 		JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) involved_in IDA
IBA
IEA		 (PMID:20061386) UniProt
GO_Central
TreeGrafter		 PMID:20061386 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136 		JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 involved_in IDA
IBA		 (PMID:20061386) UniProt
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr 3:23,203,098...23,591,925
Ensembl chr 3:23,203,020...23,591,794 		JBrowse link
G UBE2E3 ubiquitin conjugating enzyme E2 E3 involved_in IDA
IBA		 (PMID:20061386) UniProt
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr 2:180,980,360...181,063,425
Ensembl chr 2:180,967,248...181,076,585 		JBrowse link
G UBE2G1 ubiquitin conjugating enzyme E2 G1 involved_in IDA (PMID:20061386) UniProt PMID:20061386 NCBI chr17:4,269,259...4,366,675
Ensembl chr17:4,269,259...4,366,675 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in IDA
IBA
IEA
IMP		 (PMID:16307917), (PMID:20061386), (PMID:21512573), (PMID:31006531)
(PMID:25936802)		 UniProt
GO_Central
Ensembl
TreeGrafter		 PMID:16307917 PMID:20061386 PMID:21512573 PMID:25936802 PMID:31006531 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G UBE2NL ubiquitin conjugating enzyme E2 N like (gene/pseudogene) NOT|involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:143,884,071...143,885,255
Ensembl chr  X:143,884,071...143,885,255 		JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O involved_in IMP (PMID:23452853) UniProt PMID:23452853 NCBI chr17:76,389,456...76,453,152
Ensembl chr17:76,389,456...76,453,152 		JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S involved_in IDA (PMID:20061386) UniProt PMID:20061386 NCBI chr19:55,399,745...55,407,788
Ensembl chr19:55,399,745...55,407,788 		JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T involved_in IDA (PMID:20061386) UniProt PMID:20061386 NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984 		JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 involved_in IDA
IBA		 (PMID:16307917), (PMID:21512573), (PMID:31006531) UniProt
GO_Central		 PMID:16307917 PMID:21512573 PMID:31006531 GO_REF:0000033 NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:47,997,437...48,064,708
Ensembl chr 8:48,008,415...48,064,708 		JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 involved_in IDA (PMID:38225265) UniProt PMID:38225265 NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505 		JBrowse link
G WWP2 WW domain containing E3 ubiquitin protein ligase 2 involved_in ISS
IEA
IBA		 UniProt
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:69,762,332...69,941,739
Ensembl chr16:69,762,328...69,941,741 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:29452636) UniProt PMID:29452636 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase involved_in IDA (PMID:20682767) UniProt PMID:20682767 NCBI chr11:58,579,063...58,621,550
Ensembl chr11:58,579,063...58,621,550 		JBrowse link
G ZNF598 zinc finger protein 598, E3 ubiquitin ligase involved_in IDA (PMID:36302773) UniProt PMID:36302773 NCBI chr16:1,997,654...2,009,821
Ensembl chr16:1,997,654...2,009,821 		JBrowse link
negative regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP63 centrosomal protein 63 involved_in IDA (PMID:35989368) UniProt PMID:35989368 NCBI chr 3:134,485,724...134,782,559
Ensembl chr 3:134,485,699...134,587,789 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564 		JBrowse link
G MIR138-1 microRNA 138-1 involved_in IMP (PMID:23319823) ARUK-UCL PMID:23319823 NCBI chr 3:44,114,212...44,114,310
Ensembl chr 3:44,114,212...44,114,310 		JBrowse link
G MIR138-2 microRNA 138-2 involved_in IMP (PMID:23319823) ARUK-UCL PMID:23319823 NCBI chr16:56,858,518...56,858,601
Ensembl chr16:56,858,518...56,858,601 		JBrowse link
G PARP10 poly(ADP-ribose) polymerase family member 10 involved_in IMP (PMID:23575687) UniProt PMID:23575687 NCBI chr 8:143,977,158...144,012,764
Ensembl chr 8:143,977,153...144,012,772 		JBrowse link
G PLAA phospholipase A2 activating protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:26,903,372...26,947,242
Ensembl chr 9:26,903,372...26,947,242 		JBrowse link
positive regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 involved_in IDA (PMID:21931591) UniProt PMID:21931591 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:27980081) UniProt PMID:27980081 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IMP (PMID:25891078) UniProt PMID:25891078 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PEDS1-UBE2V1 PEDS1-UBE2V1 readthrough involved_in IDA (PMID:11057907) ComplexPortal PMID:11057907 NCBI chr20:50,081,124...50,153,723
Ensembl chr20:50,081,124...50,153,637 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IMP
IEA		 (PMID:23871208) UniProt
TreeGrafter
Ensembl		 PMID:23871208 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in IDA (PMID:17562858) UniProt PMID:17562858 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in IDA (PMID:10089880), (PMID:11057907) ComplexPortal PMID:10089880 PMID:11057907 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 involved_in IDA (PMID:11057907) ComplexPortal PMID:11057907 NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 involved_in IDA (PMID:10089880) ComplexPortal PMID:10089880 NCBI chr 8:47,997,437...48,064,708
Ensembl chr 8:48,008,415...48,064,708 		JBrowse link
regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SASH1 SAM and SH3 domain containing 1 acts_upstream_of_or_within IDA (PMID:23776175) MGI PMID:23776175 NCBI chr 6:148,193,468...148,552,044
Ensembl chr 6:148,272,304...148,552,044 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 12437
      primary metabolic process 10668
        protein metabolic process 4395
          protein modification process 2184
            post-translational protein modification 1003
              protein modification by small protein conjugation or removal 962
                protein modification by small protein conjugation 882
                  protein ubiquitination 796
                    protein polyubiquitination 297
                      protein K63-linked ubiquitination 76
                        negative regulation of protein K63-linked ubiquitination 6
                        positive regulation of protein K63-linked ubiquitination 9
                        regulation of protein K63-linked ubiquitination + 16
Path 2
Term Annotations click to browse term
  biological_process 19612
    metabolic process 12437
      organic substance metabolic process 11940
        macromolecule metabolic process 10219
          protein metabolic process 4395
            protein modification process 2184
              post-translational protein modification 1003
                protein modification by small protein conjugation or removal 962
                  protein modification by small protein conjugation 882
                    protein ubiquitination 796
                      protein polyubiquitination 297
                        protein K63-linked ubiquitination 76
                          negative regulation of protein K63-linked ubiquitination 6
                          positive regulation of protein K63-linked ubiquitination 9
                          regulation of protein K63-linked ubiquitination + 16
paths to the root