ZFP91 (ZFP91 zinc finger protein, atypical E3 ubiquitin ligase) - Rat Genome Database

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Gene: ZFP91 (ZFP91 zinc finger protein, atypical E3 ubiquitin ligase) Homo sapiens
Analyze
Symbol: ZFP91
Name: ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
RGD ID: 1354161
HGNC Page HGNC:14983
Description: Enables ubiquitin-protein transferase activity. Involved in protein K63-linked ubiquitination. Located in nucleolus and nucleoplasm. Implicated in stomach cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DMS-8; drug resistance-associated sequence in melanoma 8; DSM-8; DSM8; E3 ubiquitin-protein ligase ZFP91; FKSG11; FLJ57065; penta zinc finger protein; PZF; RING-type E3 ubiquitin transferase ZFP91; ZFP-91; ZFP91 zinc finger protein; zinc finger protein 757; zinc finger protein 91 homolog; zinc finger protein homologous to Zfp91 in mouse; ZNF757
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: ZFP91P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,579,063 - 58,621,550 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,579,063 - 58,621,550 (+)EnsemblGRCh38hg38GRCh38
GRCh371158,346,536 - 58,389,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,103,163 - 58,145,091 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,103,224 - 58,149,778NCBI
Celera1155,705,690 - 55,747,615 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1154,694,250 - 54,737,096 (+)NCBIHuRef
CHM1_11158,212,120 - 58,254,533 (+)NCBICHM1_1
T2T-CHM13v2.01158,528,573 - 58,571,048 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IDA)
nucleoplasm  (IDA)
nucleus  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. The ubiquitinase ZFP91 promotes tumor cell survival and confers chemoresistance through FOXA1 destabilization. Tang DE, etal., Carcinogenesis. 2020 Mar 13;41(1):56-66. doi: 10.1093/carcin/bgz085.
Additional References at PubMed
PMID:7835706   PMID:11058868   PMID:11361095   PMID:11483580   PMID:12477932   PMID:12738986   PMID:15009096   PMID:15302935   PMID:15342556   PMID:15489334   PMID:16582619   PMID:17081983  
PMID:18029348   PMID:19322201   PMID:20434516   PMID:20682767   PMID:20804734   PMID:21873635   PMID:22190034   PMID:22939629   PMID:23349640   PMID:24272675   PMID:24457600   PMID:24981860  
PMID:25281560   PMID:26167880   PMID:26186194   PMID:26496610   PMID:26949251   PMID:27144516   PMID:27248496   PMID:27926873   PMID:27975057   PMID:28514442   PMID:28530236   PMID:29045831  
PMID:29229926   PMID:29471891   PMID:29568061   PMID:29706618   PMID:30182366   PMID:30190590   PMID:30385546   PMID:31091453   PMID:31527615   PMID:31753913   PMID:31980649   PMID:32296183  
PMID:32416067   PMID:32572027   PMID:32630670   PMID:32707033   PMID:32754263   PMID:32807901   PMID:32945499   PMID:33226137   PMID:33301849   PMID:33717650   PMID:33742100   PMID:33755268  
PMID:33961781   PMID:34079125   PMID:34189442   PMID:34403361   PMID:34729304   PMID:34825365   PMID:34921745   PMID:34936696   PMID:34942311   PMID:35140242   PMID:35165513   PMID:35253629  
PMID:35320721   PMID:35439318   PMID:35831314   PMID:35850772   PMID:36089195   PMID:36090681   PMID:36215168   PMID:36217030   PMID:36232890   PMID:36244648   PMID:36375317   PMID:36379255  
PMID:36574265   PMID:37689310  


Genomics

Comparative Map Data
ZFP91
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,579,063 - 58,621,550 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,579,063 - 58,621,550 (+)EnsemblGRCh38hg38GRCh38
GRCh371158,346,536 - 58,389,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,103,163 - 58,145,091 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,103,224 - 58,149,778NCBI
Celera1155,705,690 - 55,747,615 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1154,694,250 - 54,737,096 (+)NCBIHuRef
CHM1_11158,212,120 - 58,254,533 (+)NCBICHM1_1
T2T-CHM13v2.01158,528,573 - 58,571,048 (+)NCBIT2T-CHM13v2.0
Zfp91
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391912,744,303 - 12,773,487 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1912,744,384 - 12,773,490 (-)EnsemblGRCm39 Ensembl
GRCm381912,766,939 - 12,796,123 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1912,767,020 - 12,796,126 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1912,763,660 - 12,796,126 (-)EnsemblGRCm38mm10GRCm38
MGSCv371912,840,496 - 12,870,612 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361912,832,560 - 12,862,417 (-)NCBIMGSCv36mm8
Celera1913,431,222 - 13,463,210 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.73NCBI
Zfp91
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,316,002 - 219,353,654 (-)NCBIGRCr8
mRatBN7.21209,891,344 - 209,928,890 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1209,891,344 - 209,927,762 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,265,922 - 218,302,334 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01225,183,705 - 225,220,122 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01218,020,399 - 218,056,809 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01229,602,499 - 229,640,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1229,602,499 - 229,639,187 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01236,755,856 - 236,793,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41215,846,158 - 215,882,704 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11216,013,615 - 216,015,992 (-)NCBI
Celera1207,301,610 - 207,337,819 (-)NCBICelera
Cytogenetic Map1q43NCBI
Zfp91
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555113,500,406 - 3,524,479 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555113,500,322 - 3,527,458 (+)NCBIChiLan1.0ChiLan1.0
ZFP91
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2959,743,661 - 59,785,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,769,592 - 60,812,083 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,833,437 - 53,875,435 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11157,294,324 - 57,336,369 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1157,294,678 - 57,333,088 (+)Ensemblpanpan1.1panPan2
ZFP91
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11837,762,200 - 37,809,070 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1837,299,028 - 37,345,762 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01838,415,107 - 38,461,982 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1838,411,474 - 38,461,913 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,014,444 - 38,061,617 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01837,585,181 - 37,632,297 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,207,431 - 38,254,559 (-)NCBIUU_Cfam_GSD_1.0
Zfp91
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494713,603,184 - 13,634,482 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365813,720,229 - 3,748,198 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365813,716,921 - 3,748,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFP91
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl212,495,558 - 12,531,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1212,495,548 - 12,532,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,133,497 - 12,163,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFP91
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,733,279 - 14,776,333 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,735,662 - 14,776,167 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038112,061,861 - 112,103,626 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfp91
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248641,788,879 - 1,815,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZFP91
23 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q11-12.1(chr11:55319519-58998777)x3 copy number gain See cases [RCV000142757] Chr11:55319519..58998777 [GRCh38]
Chr11:55086995..58766250 [GRCh37]
Chr11:54843571..58522826 [NCBI36]
Chr11:11q11-12.1		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_053023.5(ZFP91):c.43G>A (p.Asp15Asn) single nucleotide variant not specified [RCV004314214] Chr11:58579324 [GRCh38]
Chr11:58346797 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11p11.12-q12.1(chr11:49313405-59008426)x3 copy number gain not provided [RCV000683370] Chr11:49313405..59008426 [GRCh37]
Chr11:11p11.12-q12.1		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_053023.5(ZFP91):c.1613G>A (p.Ser538Asn) single nucleotide variant not specified [RCV004318489] Chr11:58617606 [GRCh38]
Chr11:58385079 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11q12.1(chr11:58237819-58800374)x3 copy number gain not provided [RCV001249328] Chr11:58237819..58800374 [GRCh37]
Chr11:11q12.1		 not provided
NM_053023.5(ZFP91):c.1333G>A (p.Val445Ile) single nucleotide variant not specified [RCV004295200] Chr11:58617326 [GRCh38]
Chr11:58384799 [GRCh37]
Chr11:11q12.1		 uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh37/hg19 11p11.2-q12.2(chr11:51581311-54891247)x3 copy number gain See cases [RCV002286338] Chr11:51581311..54891247 [GRCh37]
Chr11:11p11.2-q12.2		 pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_053023.5(ZFP91):c.1466G>T (p.Gly489Val) single nucleotide variant not specified [RCV004321996] Chr11:58617459 [GRCh38]
Chr11:58384932 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.255C>G (p.Ser85Arg) single nucleotide variant not specified [RCV004237904] Chr11:58579536 [GRCh38]
Chr11:58347009 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1702G>T (p.Ala568Ser) single nucleotide variant not specified [RCV004169493] Chr11:58617695 [GRCh38]
Chr11:58385168 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.448C>T (p.Arg150Trp) single nucleotide variant not specified [RCV004119633] Chr11:58609907 [GRCh38]
Chr11:58377380 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.526G>A (p.Gly176Ser) single nucleotide variant not specified [RCV004206659] Chr11:58609985 [GRCh38]
Chr11:58377458 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.167G>A (p.Arg56Gln) single nucleotide variant not specified [RCV004116427] Chr11:58579448 [GRCh38]
Chr11:58346921 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.286C>G (p.Pro96Ala) single nucleotide variant not specified [RCV004099141] Chr11:58579567 [GRCh38]
Chr11:58347040 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1402G>A (p.Ala468Thr) single nucleotide variant not specified [RCV004150202] Chr11:58617395 [GRCh38]
Chr11:58384868 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.307T>G (p.Ser103Ala) single nucleotide variant not specified [RCV004102549] Chr11:58579588 [GRCh38]
Chr11:58347061 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.199G>T (p.Ala67Ser) single nucleotide variant not specified [RCV004168175] Chr11:58579480 [GRCh38]
Chr11:58346953 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.427A>T (p.Ile143Phe) single nucleotide variant not specified [RCV004269726] Chr11:58609886 [GRCh38]
Chr11:58377359 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.872G>A (p.Arg291Gln) single nucleotide variant not specified [RCV004275196] Chr11:58612292 [GRCh38]
Chr11:58379765 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.95G>A (p.Arg32Gln) single nucleotide variant not specified [RCV004333917] Chr11:58579376 [GRCh38]
Chr11:58346849 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.140G>A (p.Ser47Asn) single nucleotide variant not specified [RCV004359868] Chr11:58579421 [GRCh38]
Chr11:58346894 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.400G>A (p.Asp134Asn) single nucleotide variant not specified [RCV004339284] Chr11:58609859 [GRCh38]
Chr11:58377332 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3 copy number gain not specified [RCV003986918] Chr11:50398499..63924462 [GRCh37]
Chr11:11p11.12-q13.1		 likely pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
NM_053023.5(ZFP91):c.128G>A (p.Gly43Glu) single nucleotide variant not specified [RCV004486131] Chr11:58579409 [GRCh38]
Chr11:58346882 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.53G>A (p.Gly18Glu) single nucleotide variant not specified [RCV004486142] Chr11:58579334 [GRCh38]
Chr11:58346807 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.133A>C (p.Thr45Pro) single nucleotide variant not specified [RCV004486132] Chr11:58579414 [GRCh38]
Chr11:58346887 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1657A>T (p.Ile553Leu) single nucleotide variant not specified [RCV004486134] Chr11:58617650 [GRCh38]
Chr11:58385123 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1705G>A (p.Gly569Arg) single nucleotide variant not specified [RCV004486136] Chr11:58617698 [GRCh38]
Chr11:58385171 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.278G>C (p.Gly93Ala) single nucleotide variant not specified [RCV004486138] Chr11:58579559 [GRCh38]
Chr11:58347032 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.488G>T (p.Arg163Leu) single nucleotide variant not specified [RCV004486140] Chr11:58609947 [GRCh38]
Chr11:58377420 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.53G>T (p.Gly18Val) single nucleotide variant not specified [RCV004486143] Chr11:58579334 [GRCh38]
Chr11:58346807 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1663G>T (p.Gly555Cys) single nucleotide variant not specified [RCV004486135] Chr11:58617656 [GRCh38]
Chr11:58385129 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.251C>T (p.Pro84Leu) single nucleotide variant not specified [RCV004486137] Chr11:58579532 [GRCh38]
Chr11:58347005 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.848C>T (p.Pro283Leu) single nucleotide variant not specified [RCV004486144] Chr11:58611729 [GRCh38]
Chr11:58379202 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.331C>T (p.Pro111Ser) single nucleotide variant not specified [RCV004486139] Chr11:58579612 [GRCh38]
Chr11:58347085 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.502A>G (p.Thr168Ala) single nucleotide variant not specified [RCV004486141] Chr11:58609961 [GRCh38]
Chr11:58377434 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_053023.5(ZFP91):c.1507A>G (p.Thr503Ala) single nucleotide variant not specified [RCV004486133] Chr11:58617500 [GRCh38]
Chr11:58384973 [GRCh37]
Chr11:11q12.1		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR29Ahsa-miR-29a-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:1515
Count of miRNA genes:831
Interacting mature miRNAs:988
Transcripts:ENST00000316059
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D11S4202  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,366,189 - 58,366,419UniSTSGRCh37
Build 361158,122,765 - 58,122,995RGDNCBI36
Celera1155,725,292 - 55,725,518RGD
Cytogenetic Map11q12UniSTS
Cytogenetic Map11q12.2UniSTS
HuRef1154,713,845 - 54,714,071UniSTS
Marshfield Genetic Map1158.4UniSTS
Marshfield Genetic Map1158.4RGD
Genethon Genetic Map1163.0UniSTS
deCODE Assembly Map1164.21UniSTS
Whitehead-YAC Contig Map11 UniSTS
STS-AA036951  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,385,043 - 58,385,217UniSTSGRCh37
Build 361158,141,619 - 58,141,793RGDNCBI36
Celera1155,744,143 - 55,744,317RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,733,116 - 54,733,290UniSTS
GeneMap99-GB4 RH Map11218.49UniSTS
WI-12111  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,388,304 - 58,388,403UniSTSGRCh37
Build 361158,144,880 - 58,144,979RGDNCBI36
Celera1155,747,404 - 55,747,503RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,736,377 - 54,736,476UniSTS
GeneMap99-GB4 RH Map11218.49UniSTS
Whitehead-RH Map11284.0UniSTS
SHGC-30116  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,386,810 - 58,386,959UniSTSGRCh37
Build 361158,143,386 - 58,143,535RGDNCBI36
Celera1155,745,910 - 55,746,059RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,734,883 - 54,735,032UniSTS
TNG Radiation Hybrid Map1125753.0UniSTS
GeneMap99-G3 RH Map112477.0UniSTS
RH79883  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,386,699 - 58,386,940UniSTSGRCh37
Build 361158,143,275 - 58,143,516RGDNCBI36
Celera1155,745,799 - 55,746,040RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,734,772 - 54,735,013UniSTS
D11S3594  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,359,925 - 58,360,088UniSTSGRCh37
Build 361158,116,501 - 58,116,664RGDNCBI36
Celera1155,719,028 - 55,719,191RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,707,582 - 54,707,745UniSTS
SHGC-106382  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,347,852 - 58,348,169UniSTSGRCh37
Build 361158,104,428 - 58,104,745RGDNCBI36
Celera1155,706,955 - 55,707,272RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,695,515 - 54,695,832UniSTS
TNG Radiation Hybrid Map1125758.0UniSTS
RH78256  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,386,702 - 58,386,823UniSTSGRCh37
Build 361158,143,278 - 58,143,399RGDNCBI36
Celera1155,745,802 - 55,745,923RGD
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map11q12UniSTS
HuRef1154,734,775 - 54,734,896UniSTS
GeneMap99-GB4 RH Map11219.66UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2426 2550 1617 523 1679 365 4353 2054 3608 391 1441 1605 171 1203 2788 5
Low 13 441 109 101 272 100 3 142 126 28 19 8 4 1 1 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000316059   ⟹   ENSP00000339030
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1158,579,063 - 58,621,550 (+)Ensembl
RefSeq Acc Id: NM_001197051   ⟹   NP_001183980
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,579,063 - 58,621,550 (+)NCBI
GRCh371158,346,587 - 58,389,023 (+)ENTREZGENE
HuRef1154,694,250 - 54,737,096 (+)ENTREZGENE
CHM1_11158,212,120 - 58,254,533 (+)NCBI
T2T-CHM13v2.01158,528,573 - 58,571,048 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053023   ⟹   NP_444251
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,579,063 - 58,621,550 (+)NCBI
GRCh371158,346,587 - 58,389,023 (+)ENTREZGENE
Build 361158,103,163 - 58,145,091 (+)NCBI Archive
Celera1155,705,690 - 55,747,615 (+)RGD
HuRef1154,694,250 - 54,737,096 (+)ENTREZGENE
CHM1_11158,212,120 - 58,254,533 (+)NCBI
T2T-CHM13v2.01158,528,573 - 58,571,048 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_444251   ⟸   NM_053023
- Peptide Label: isoform 1
- UniProtKB: Q96JP4 (UniProtKB/Swiss-Prot),   Q86V47 (UniProtKB/Swiss-Prot),   A8MSG7 (UniProtKB/Swiss-Prot),   A6NHC4 (UniProtKB/Swiss-Prot),   Q96QA3 (UniProtKB/Swiss-Prot),   Q96JP5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001183980   ⟸   NM_001197051
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSP00000339030   ⟸   ENST00000316059

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96JP5-F1-model_v2 AlphaFold Q96JP5 1-570 view protein structure

Promoters
RGD ID:6789603
Promoter ID:HG_KWN:12965
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:ENST00000389918,   ENST00000389919,   OTTHUMT00000268674,   UC001NMY.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361158,102,686 - 58,103,642 (+)MPROMDB
RGD ID:7220387
Promoter ID:EPDNEW_H15939
Type:initiation region
Name:ZFP91_3
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,577,764 - 58,577,824EPDNEW
RGD ID:7220389
Promoter ID:EPDNEW_H15940
Type:initiation region
Name:ZFP91_12
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,578,177 - 58,578,237EPDNEW
RGD ID:7220393
Promoter ID:EPDNEW_H15942
Type:initiation region
Name:ZFP91_1
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,578,498 - 58,578,558EPDNEW
RGD ID:7220397
Promoter ID:EPDNEW_H15943
Type:initiation region
Name:ZFP91_2
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,579,155 - 58,579,215EPDNEW
RGD ID:7220395
Promoter ID:EPDNEW_H15944
Type:initiation region
Name:ZFP91_5
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,579,559 - 58,579,619EPDNEW
RGD ID:7220401
Promoter ID:EPDNEW_H15945
Type:initiation region
Name:ZFP91_7
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,611,027 - 58,611,087EPDNEW
RGD ID:7220399
Promoter ID:EPDNEW_H15946
Type:initiation region
Name:ZFP91_10
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,611,605 - 58,611,665EPDNEW
RGD ID:7220403
Promoter ID:EPDNEW_H15947
Type:initiation region
Name:ZFP91_6
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,617,459 - 58,617,519EPDNEW
RGD ID:7220405
Promoter ID:EPDNEW_H15948
Type:initiation region
Name:ZFP91_4
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15949  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,618,423 - 58,618,483EPDNEW
RGD ID:7220407
Promoter ID:EPDNEW_H15949
Type:initiation region
Name:ZFP91_8
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15950  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,618,996 - 58,619,056EPDNEW
RGD ID:7220409
Promoter ID:EPDNEW_H15950
Type:initiation region
Name:ZFP91_11
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15951  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,620,244 - 58,620,304EPDNEW
RGD ID:7220411
Promoter ID:EPDNEW_H15951
Type:initiation region
Name:ZFP91_9
Description:ZFP91 zinc finger protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15939  EPDNEW_H15940  EPDNEW_H15942  EPDNEW_H15944  EPDNEW_H15943  EPDNEW_H15946  EPDNEW_H15945  EPDNEW_H15947  EPDNEW_H15948  EPDNEW_H15949  EPDNEW_H15950  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,620,672 - 58,620,732EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14983 AgrOrtholog
COSMIC ZFP91 COSMIC
Ensembl Genes ENSG00000186660 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000316059 ENTREZGENE
  ENST00000316059.7 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000186660 GTEx
HGNC ID HGNC:14983 ENTREZGENE
Human Proteome Map ZFP91 Human Proteome Map
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:80829 UniProtKB/Swiss-Prot
NCBI Gene 80829 ENTREZGENE
OMIM 619289 OMIM
PANTHER ZINC FINGER PROTEIN 142 UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 653 UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA37955 PharmGKB
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A6NHC4 ENTREZGENE
  A8MSG7 ENTREZGENE
  Q86V47 ENTREZGENE
  Q96JP4 ENTREZGENE
  Q96JP5 ENTREZGENE
  Q96QA3 ENTREZGENE
  ZFP91_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A6NHC4 UniProtKB/Swiss-Prot
  A8MSG7 UniProtKB/Swiss-Prot
  Q86V47 UniProtKB/Swiss-Prot
  Q96JP4 UniProtKB/Swiss-Prot
  Q96QA3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-04-20 ZFP91  ZFP91 zinc finger protein, atypical E3 ubiquitin ligase  ZFP91  ZFP91 zinc finger protein  Symbol and/or name change 19259463 PROVISIONAL
2012-12-04 ZFP91  ZFP91 zinc finger protein    zinc finger protein 91 homolog (mouse)  Symbol and/or name change 5135510 APPROVED